Preliminary investigation of high-dose tranexamic acid for controlling intraoperative blood loss in patients undergoing spine correction surgery

Spine Journal

Volumn 15, Issue 4, 2015, Pages 647-654

  Xie, Jingming ^a   Lenke, Lawrence G ^b   Li, Tao ^a   Si, Yongyu ^a   Zhao, Zhi ^a   Wang, Yingsong ^a   Zhang, Ying ^a   Xiao, Jie ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood loss; Blood transfusion; Posterior spinal deformity corrective surgery; Posterior vertebral column resection; Spinal deformities; Tranexamic acid

Indexed keywords

CREATININE; FRESH FROZEN PLASMA; HEMOGLOBIN; LIVER ENZYME; TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

ACUTE KIDNEY FAILURE; ADOLESCENT; ADULT; ARTICLE; BLOOD CELL COUNT; BLOOD CLOTTING; BLOOD TRANSFUSION; BLOOD VOLUME; BREATHING; CHEST TIGHTNESS; CHILD; COLLOID; CONSCIOUSNESS LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRYSTALLOID; DEEP VEIN THROMBOSIS; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; FEMALE; HEART INFARCTION; HEMATOCRIT; HUMAN; KIDNEY FUNCTION; LEG THROMBOSIS; LIVER FAILURE; LIVER FUNCTION; LIVER TOXICITY; LOADING DRUG DOSE; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; OPERATIVE BLOOD LOSS; OUTCOME ASSESSMENT; PARTIAL THROMBOPLASTIN TIME; PLASTIC SURGERY; POSTERIOR VERTEBRAL COLUMN RESECTION; PRIORITY JOURNAL; PROTHROMBIN TIME; RETROSPECTIVE STUDY; SEIZURE; SKIN INCISION; SPINE MALFORMATION; SPINE SURGERY; STATISTICAL SIGNIFICANCE; THROMBOCYTE TRANSFUSION; URINE VOLUME; BLOOD LOSS, SURGICAL; CONTROLLED CLINICAL TRIAL; MIDDLE AGED; SPINE; SURGERY;

ADOLESCENT; ADULT; ANTIFIBRINOLYTIC AGENTS; BLOOD LOSS, SURGICAL; CHILD; FEMALE; HUMANS; MALE; MIDDLE AGED; SPINE; TRANEXAMIC ACID;

EID: 84925446838     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2014.11.023     Document Type: Article

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