Neuro-imaging findings in infants with congenital cytomegalovirus infection: Relation to trimester of infection

Neonatology

Volumn 107, Issue 4, 2015, Pages 289-296

  Oosterom, Natanja ^a   Nijman, Joppe ^a   Gunkel, Julia ^a   Wolfs, Tom F W ^b   Groenendaal, Floris ^a   Verboon Maciolek, Malgosia A ^a   De Vries, Linda S ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Congenital infection; Cytomegalovirus; Neuro imaging; Outcome; Trimester of pregnancy

Indexed keywords

APGAR SCORE; ARTICLE; BAYLEY SCALES OF INFANT DEVELOPMENT; BRAIN DISEASE; BRAIN MALFORMATION; BRAIN VENTRICLE DILATATION; CEREBELLUM HYPOPLASIA; CEREBRAL PALSY; CLINICAL ARTICLE; COGNITIVE DEFECT; CONGENITAL CYTOMEGALOVIRUS INFECTION; CONGENITAL INFECTION; CONVULSION; CYTOMEGALOVIRUS INFECTION; DEMOGRAPHY; ECHOENCEPHALOGRAPHY; EPILEPSY; EVALUATION STUDY; FEMALE; FIRST TRIMESTER PREGNANCY; FOLLOW UP; GERMINOLYTIC CYST; HEPATITIS; HUMAN; HYPERBILIRUBINEMIA; INFANT; INFANT DISEASE; LENTICULOSTRIATE VASCULOPATHY; MALE; MICROCEPHALY; MIGRATIONAL DISORDER; NEONATAL THROMBOCYTOPENIA; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCEPTION DEAFNESS; PREGNANCY; PREGNANCY OUTCOME; PRIORITY JOURNAL; REAL TIME ULTRASOUND SCANNER; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; THROMBOCYTOPENIA; VASCULAR DISEASE; WHOLE BODY SCANNER; BRAIN DISEASES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; NETHERLANDS; NEWBORN; PREGNANCY COMPLICATION; PREMATURITY; VIROLOGY;

CYTOMEGALOVIRUS;

BRAIN DISEASES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; ECHOENCEPHALOGRAPHY; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MAGNETIC RESONANCE IMAGING; MALE; NETHERLANDS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY OUTCOME; PREGNANCY TRIMESTERS;

EID: 84925389915     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000375439     Document Type: Article

References (28)

1. Dollard SC, Grosse SD, Ross DS: New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Rev Med Virol 2007;17:355-363.
2. Malm G, Engman ML: Congenital cytomegalovirus infections. Semin Fetal Neonatal Med 2007;12:154-159.
3. Lombardi G, Garofoli F, Stronati M: Congenital cytomegalovirus infection: treatment, sequelae and follow-up. J Matern Fetal Neonatal Med 2010;23(suppl 3):45-48.
4. Foulon I, Naessens A, Foulon W, Casteels A, Gordts F: A 10-year prospective study of sensorineural hearing loss in children with congenital cytomegalovirus infection. J Pediatr 2008;153:84-88.
5. Enders G, Daiminger A, Bader U, Exler S, Enders M: Intrauterine transmission and clinical outcome of 248 pregnancies with primary cytomegalovirus infection in relation to gestational age. J Clin Virol 2011;52:244-246.
6. Ancora G, Lanari M, Lazzarotto T, Venturi V, Tridapalli E, Sandri F, Menarini M, Ferretti E, Faldella G: Cranial ultrasound scanning and prediction of outcome in newborns with congenital cytomegalovirus infection. J Pediatr 2007;150:157-161.
7. Noyola DE, Demmler GJ, Nelson CT, Griesser C, Williamson WD, Atkins JT, Rozelle J, Turcich M, Llorente AM, Sellers-Vinson S, Reynolds A, Bale JF Jr, Gerson P, Yow MD; Houston Congenital CMV Longitudinal Study Group: Early predictors of neurodevelopmental outcome in symptomatic congenital cytomegalovirus infection. J Pediatr 2001;138:325-331.
8. De Vries LS, Gunardi H, Barth PG, Bok LA, Verboon-Maciolek MA, Groenendaal F: The spectrum of cranial ultrasound and magnetic resonance imaging abnormalities in congenital cytomegalovirus infection. Neuropediatrics 2004;35:113-119.
9. Lanari M, Capretti MG, Lazzarotto T, Gabrielli L, Rizzollo S, Mostert M, Manzoni P: Neuroimaging in CMV congenital infected neonates: how and when. Early Hum Dev 2012;88(suppl 2):S3-S5.
10. Manara R, Balao L, Baracchini C, Drigo P, D'Elia R, Ruga EM: Brain magnetic resonance findings in symptomatic congenital cytomegalovirus infection. Pediatr Radiol 2011; 41: 962-970.
11. Boesch C, Issakainen J, Kewitz G, Kikinis R, Martin E, Boltshauser E: Magnetic resonance imaging of the brain in congenital cytomegalovirus infection. Pediatr Radiol 1989; 19: 91-93.
12. Alarcon A, Martinez-Biarge M, Cabanas F, Hernanz A, Quero J, Garcia-Alix A, Ancora G, Lanari M, Lazzarotto T, Venturi V, Tridapalli E, Sandri F, Menarini M, Ferretti E, Faldella G: Clinical, biochemical, and neuroimaging findings predict long-term neurodevelopmental outcome in symptomatic congenital cytomegalovirus infection. Cranial ultrasound scanning and prediction of outcome in newborns with congenital cytomegalovirus infection. J Pediatr 2013;163:828-834.
13. Van Doornum GJ, Guldemeester J, Osterhaus AD, Niesters HG: Diagnosing herpesvirus infections by real-time amplification and rapid culture. J Clin Microbiol 2003; 41: 576-580.
14. Nijman J, de Vries LS, Koopman-Esseboom C, Uiterwaal CS, van Loon AM, Verboon-Maciolek MA: Postnatally acquired cytomegalovirus infection in preterm infants: A prospective study on risk factors and cranial ultrasound findings. Arch Dis Child Fetal Neonatal Ed 2012;97:F259-F263.
15. Visser GH, Eilers PH, Elferink-Stinkens PM, Merkus HM, Wit JM: New Dutch reference curves for birthweight by gestational age. Early Hum Dev 2009;85:737-744.
16. Griffiths R: The Abilities of Young Children. A Comprehensive System of Mental Measurement for the First Eight Years of Life. London, The Test Agency, 1984.
17. Bayley N: Bayley Scales of Infant and Toddler Development. San Antonio, Harcourt, 2006.
18. Schneeberger PM, Groenendaal F, de Vries LS, van Loon AM, Vroom TM: Variable outcome of a congenital cytomegalovirus infection in a quadruplet after primary infection of the mother during pregnancy. Acta Paediatr 1994; 83: 986-989.
19. Lipitz S, Yinon Y, Malinger G, Yagel S, Levit L, Hoffman C, Rantzer R, Weisz B: Risk of cytomegalovirus-associated sequelae in relation to time of infection and findings on prenatal imaging. Ultrasound Obstet Gynecol 2013;41:508-514.
20. Picone O, Vauloup-Fellous C, Cordier AG, Guitton S, Senat MV, Fuchs F, Ayoubi JM, Grangeot Keros L, Benachi A: A series of 238 cytomegalovirus primary infections during pregnancy: description and outcome. Prenat Diagn 2013;33:751-758.
21. Barkovich AJ, Lindan CE: Congenital cytomegalovirus infection of the brain: imaging analysis and embryologic considerations. AJNR Am J Neuroradiol 1994; 15: 703-715.
22. Picone O, Simon I, Benachi A, Brunelle F, Sonigo P: Comparison between ultrasound and magnetic resonance imaging in assessment of fetal cytomegalovirus infection. Prenat Diagn 2008;28:753-758.
23. Capretti MG, Lanari M, Tani G, Ancora G, Sciutti R, Marsico C, Lazzarotto T, Gabrielli L, Guerra B, Corvaglia L, Faldella G: Role of cerebral ultrasound and magnetic resonance imaging in newborns with congenital cytomegalovirus infection. Brain Dev 2014; 36:203-211.
24. Chang BS, Piao X, Giannini C, Cascino GD, Scheffer I, Woods CG, Topcu M, Tezcan K, Bodell A, Leventer RJ, Barkovich AJ, Grant PE, Walsh CA: Bilateral generalized polymicrogyria (BGP): A distinct syndrome of cortical malformation. Neurology 2004; 62: 1722-1728.
25. Van der Knaap MS, Vermeulen G, Barkhof F, Hart AA, Loeber JG, Weel JF: Pattern of white matter abnormalities at MR imaging: use of polymerase chain reaction testing of Guthrie cards to link pattern with congenital cytomegalovirus infection. Radiology 2004;230:529-536.
26. Nijman J, Gunkel J, de Vries LS, van Kooij BJ, van Haastert IC, Benders MJ, Kersbergen KJ, Verboon-Maciolek MA, Groenendaal F: Reduced occipital fractional anisotropy on cerebral diffusion tensor imaging in preterm infants with postnatally acquired cytomegalovirus infection. Neonatology 2013;104:143-150.
27. Fowler KB, Stagno S, Pass RF, Britt WJ, Boll TJ, Alford CA: The outcome of congenital cytomegalovirus infection in relation to maternal antibody status. N Engl J Med 1992;326:663-667.
28. Lanari M, Lazzarotto T, Venturi V, Papa I, Gabrielli L, Guerra B, Landini MP, Faldella G: Neonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic congenitally infected newborns. Pediatrics 2006;117:e76-e83.