The prevalence of BRCA1 and BRCA2 mutations among young Mexican women with triple-negative breast cancer

Breast Cancer Research and Treatment

Volumn 150, Issue 2, 2015, Pages 389-394

  Villarreal Garza, C ^a,b   Weitzel, J N ^c   Llacuachaqui, M ^d   Sifuentes, E ^a   Magallanes Hoyos, M C ^a   Gallardo, L ^a   Alvarez Gomez R M ^a   Herzog, J ^c   Castillo, D ^c   Royer, R ^d   Akbari, Mohammad ^d   Lara Medina, F ^a   Herrera, L A ^a   Mohar, A ^a   Narod, S A ^d  

^a INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

^b SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^d WOMEN S COLLEGE HOSPITAL   (Canada)

Author keywords

BRCA1; BRCA2; Mexico; Triple negative breast cancer

Indexed keywords

BRCA1 PROTEIN; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN; BRCA2 PROTEIN, HUMAN;

ADULT; FEMALE; GENETICS; HUMAN; MEXICO; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PREVALENCE; TRIPLE NEGATIVE BREAST NEOPLASMS; YOUNG ADULT;

ADULT; BRCA1 PROTEIN; BRCA2 PROTEIN; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; MEXICO; MIDDLE AGED; MUTATION; PREVALENCE; TRIPLE NEGATIVE BREAST NEOPLASMS; YOUNG ADULT;

EID: 84925389000     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-015-3312-8     Document Type: Article

References (50)

1. Data. ISabciM-Ot-N. [cited November 14, 2014]. Available from: http://www.inegi.org.mx/inegi/contenidos/espanol/prensa/Contenidos/estadisticas/2014/mama0.pdf
2. Knaul FM, Nigenda G, Lozano R, Arreola-Ornelas H, Langer A, Frenk J (2008) Breast cancer in Mexico: a pressing priority. Reprod Health Matters 16:113–123
3. Chavarri-Guerra Y, Villarreal-Garza C, Liedke PE et al (2012) Breast cancer in Mexico: a growing challenge to health and the health system. Lancet Oncol 13:e335–e343
4. Weissman BE, Saxon PJ, Pasquale SR, Jones GR, Geiser AG, Stanbridge EJ (1987) Introduction of a normal human chromosome 11 into a Wilms’ tumor cell line controls its tumorigenic expression. Science 236:175–180
5. Rodriguez-Cuevas S, Guisa-Hohenstein F, Labastida-Almendaro S (2009) First breast cancer mammography screening program in Mexico: initial results 2005-2006. Breast J 15:623–631
6. Mohar A, Bargallo E, Ramirez MT, Lara F, Beltran-Ortega A (2009) Available resources for the treatment of breast cancer in Mexico. Salud Publica Mex 51(Suppl 2):s263–s269
7. Lara-Medina F, Perez-Sanchez V, Saavedra-Perez D et al (2011) Triple-negative breast cancer in Hispanic patients: high prevalence, poor prognosis, and association with menopausal status, body mass index, and parity. Cancer 117:3658–3669
8. Villarreal-Garza C, Aguila C, Magallanes-Hoyos MC et al (2013) Breast cancer in young women in Latin America: an unmet, growing burden. Oncologist 18(Suppl):26–34
9. Trudeau M, Pritchard KI et al (2007) Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 13:4429–4434
10. Solano AR, Aceto GM, Delettieres D et al (2012) BRCA1 And BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin. Springerplus 1:20
11. Gomes MC, Costa MM, Borojevic R et al (2007) Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Brazil. Breast Cancer Res Treat 103:349–353
12. Gonzalez-Hormazabal P, Gutierrez-Enriquez S et al (2011) Spectrum of BRCA1/2 point mutations and genomic rearrangements in high-risk breast/ovarian cancer Chilean families. Breast Cancer Res Treat 126:705–716
13. Hernandez JE, Llacuachaqui M, Palacio GV et al (2014) Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from medellin, Colombia. Hered Cancer Clin Pract 12:11
14. Gutierrez Espeleta GA, Llacuachaqui M, Garcia-Jimenez L et al (2012) BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica. Clin Genet 82(5):484–488
15. Vidal-Millan S, Taja-Chayeb L, Gutierrez-Hernandez O et al (2009) Mutational analysis of BRCA1 and BRCA2 genes in Mexican breast cancer patients. Eur J Gynaecol Oncol 30:527–530
16. Calderón-Garcidueñas AL, Ruiz-Flores P, Cerda-Flores RM, Barrera-Saldaña HA (2005) Clinical follow up of Mexican women with early onset of breast cancer and mutations in the BRCA1 and BRCA2 genes. Salud Publica Mex 47(2):110–115
17. Vaca-Paniagua F, Alvarez-Gomez RM, Fragoso-Ontiveros V et al (2012) Full-Exon pyrosequencing screening of BRCA germline mutations in Mexican women with inherited breast and ovarian cancer. PLoS ONE 7:e37432
18. Villarreal-Garza C, Alvarez-Gomez RM, Perez-Plasencia C et al (2014) Significant clinical impact of recurrent BRCA1 and BRCA2 mutations in Mexico, September 18. Cancer. doi:10.1002/cncr.29058
19. Torres-Mejia G, Royer R, Llacuachaqui M, et al (2014) Recurrent BRCA1 and BRCA2 mutations in Mexican women with breast cancer. Cancer Epidemiol Biomark Prev
20. Delgado L, Fernandez G, Grotiuz G et al (2011) BRCA1 and BRCA2 germline mutations in Uruguayan breast and breast-ovarian cancer families. Identification of novel mutations and unclassified variants. Breast Cancer Res Treat 128(1):211–218
21. Lara K, Consigliere N, Perez J, Porco A (2012) BRCA1 and BRCA2 mutations in breast cancer patients from Venezuela. Biol Res 45:117–130
22. Narod SA (2009) Screening for BRCA1 and BRCA2 mutations in breast cancer patients from Mexico: the public health perspective. Salud Publica Mex 51(Suppl 2):s191–s196
23. Weitzel JN, Lagos V, Blazer KR et al (2005) Prevalence of BRCA mutations and founder effect in high-risk Hispanic families. Cancer Epidemiol Biomark Prev 14:1666–1671
24. Weitzel JN, Lagos VI, Herzog JS et al (2007) Evidence for common ancestral origin of a recurring BRCA1 genomic rearrangement identified in high-risk Hispanic families. Cancer Epidemiol Biomark Prev 16:1615–1620
25. Weitzel JN, Clague J, Martir-Negron A et al (2013) Prevalence and type of BRCA mutations in Hispanics undergoing genetic cancer risk assessment in the southwestern United States: a report from the Clinical Cancer Genetics Community Research Network. J Clin Oncol 31:210–216
26. Gallardo M, Silva A, Rubio L et al (2006) Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations. Breast Cancer Res Treat 95:81–87
27. Torres D, Rashid MU, Gil F et al (2007) High proportion of BRCA1/2 founder mutations in Hispanic breast/ovarian cancer families from Colombia. Breast Cancer Res Treat 103:225–232
28. Vogel KJ, Atchley DP, Erlichman J et al (2007) BRCA1 and BRCA2 genetic testing in Hispanic patients: mutation prevalence and evaluation of the BRCAPRO risk assessment model. J Clin Oncol 25:4635–4641
29. Jara L, Ampuero S, Santibanez E et al (2004) Molecular analysis of the eighteen most frequent mutations in the BRCA1 gene in 63 Chilean breast cancer families. Biol Res 37:469–481
30. Diez O, Osorio A, Duran M et al (2003) Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects. Hum Mutat 22:301–312
31. de la Hoya M, Gutierrez-Enriquez S, Velasco E et al (2006) Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ovarian cancer. Clin Chem 52:1480–1485
32. Blesa JR, Garcia JA, Ochoa E (2000) Frequency of germ-line BRCA1 mutations among Spanish families from a Mediterranean area. Hum Mutat 15:381–382
33. Campos B, Diez O, Domenech M et al (2001) BRCA2 mutation analysis of 87 Spanish breast/ovarian cancer families. Ann Oncol 12:1699–1703
34. Green ED, Olson MV (1990) Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping. Science 250:94–98
35. Hall MJ, Reid JE, Burbridge LA, Pruss D, Deffenbaugh AM et al (2009) BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast -ovarian cancer. Cancer 115(10):2222–2233
36. Olopade OI, Fackenthal JD, Dunston G, Tainsky MA, Collins F, Whitfield-Broome C (2003) Breast cancer genetics in African Americans. Cancer 97(1 Suppl):236–245
37. Donenberg T, Lunn J, Curling D et al (2011) A high prevalence of BRCA1 mutations among breast cancer patients from the Bahamas. Breast Cancer Res Treat 125:591–596
38. Breast Cancer Information Core (BIC). An open access online breast cancer mutation data base. 2010
39. Vega A, Campos B, Bressac-De-Paillerets B et al (2001) The R71G BRCA1 is a founder Spanish mutation and leads to aberrant splicing of the transcript. Hum Mutat 17:520–521
40. Jara L, Ampuero S, Santibanez E et al (2006) BRCA1 and BRCA2 mutations in a South American population. Cancer Genet Cytogenet 166:36–45
41. Abugattas J, Llacuachaqui M, Allende YS et al (2014) Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Peru. Clin Genet. doi:10.1111/cge.12505
42. Torres D, Umaña A, Robledo JF et al (2009) Estudio de factores genéticos para cáncer de mama en Colombia, Spanish. Univ Med Bogotá (Colombia) 50:297–301
43. Martinez ME ea. Family history of breast and ovarian cancer prevalence and its association with triple negative subtype in hispanic women. American Association for Cancer Research Science of Cancer Health Disparities Meeting; San Antonio, TX November 9–12, 2014
44. Young SR, Pilarski RT, Donenberg T et al (2009) The prevalence of BRCA1 mutations among young women with triple-negative breast cancer. BMC Cancer 9:86
45. Fostira F, Tsitlaidou M, Gogas H, et al (2010) Prevalence of BRCA1 mutations among 284 women with triple-negative breast cancer. ASCO Meeting Abstracts 28(15_suppl %U http://meeting.ascopubs.org/cgi/content/abstract/28/15_suppl/1511):1511
46. Gonzalez-Angulo AM, Timms KM et al (2011) Incidence and outcome of BRCA mutations in unselected patients with triple receptor-negative breast cancer, February 22. Clin Cancer Res 17(5):1082–1089
47. Couch FJ, Hart SN, Sharma P, et al. Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. J Clin Oncol In press
48. Byrski T, Huzarski T, Dent R et al (2014) Pathologic complete response to neoadjuvant cisplatin in BRCA1-positive breast cancer patients. Breast Cancer Res Treat 147:401–405
49. Huzarski T, Byrski T, Gronwald J et al (2013) Ten-year survival in patients with BRCA1-negative and BRCA1-positive breast cancer. J Clin Oncol 31:3191–3196
50. Metcalfe K, Gershman S, Ghadirian P et al (2014) Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis. BMJ 348:g226