Atorvastatin promotes human monocyte differentiation toward alternative M2 macrophages through p38 mitogen-activated protein kinase-dependent peroxisome proliferator-activated receptor γ activation

International Immunopharmacology

Volumn 26, Issue 1, 2015, Pages 58-64

  Zhang, Ou ^a,b   Zhang, Jinying ^a  

^a ZHENGZHOU UNIVERSITY   (China)

^b First Hospital Affiliated to Nanyang Medical College   (China)

Author keywords

Atherosclerosis; Atorvastatin; M2 macrophages; Monocyte; p38 MAPK; PPAR

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ATORVASTATIN; CCL18 ANTIGEN; CD163 ANTIGEN; CD206 ANTIGEN; CELL ANTIGEN; FATTY ACID BINDING PROTEIN 4; INTERLEUKIN 10; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DOSE RESPONSE; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; M2 MACROPHAGE; MACROPHAGE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; BLOOD; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; MONONUCLEAR CELL; REAL TIME POLYMERASE CHAIN REACTION;

ATORVASTATIN CALCIUM; BIOMARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; CORONARY ARTERY DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LEUKOCYTES, MONONUCLEAR; MACROPHAGE ACTIVATION; MACROPHAGES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR GAMMA; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84925352058     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.03.005     Document Type: Article

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