Hodgkin transformation of chronic lymphocytic leukemia: Incidence, outcomes, and comparison to de novo Hodgkin lymphoma

American Journal of Hematology

Volumn 90, Issue 4, 2015, Pages 334-338

  Parikh, Sameer A ^a   Habermann, Thomas M ^a   Chaffee, Kari G ^a   Call, Timothy G ^a   Ding, Wei ^a   Leis, Jose F ^b   Macon, William R ^a   Schwager, Susan M ^a   Ristow, Kay M ^a   Porrata, Luis F ^a   Kay, Neil E ^a   Slager, Susan L ^a   Shanafelt, Tait D ^a  

^a MAYO CLINIC   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER INCIDENCE; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DE NOVO HODGKIN LYMPHOMA; FEMALE; FOLLOW UP; HODGKIN DISEASE; HUMAN; IN SITU HYBRIDIZATION; INTERNATIONAL PROGNOSTIC SCORING SYSTEM; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; CELL TRANSFORMATION; COMPARATIVE STUDY; COMPLICATION; DISEASE FREE SURVIVAL; FACTUAL DATABASE; INCIDENCE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MIDDLE AGED; PATHOLOGY; PROSPECTIVE STUDY; RISK FACTOR; VERY ELDERLY;

ANTINEOPLASTIC AGENT;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL TRANSFORMATION, NEOPLASTIC; DATABASES, FACTUAL; DISEASE-FREE SURVIVAL; FEMALE; HODGKIN DISEASE; HUMANS; INCIDENCE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84925325517     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.23939     Document Type: Article

References (32)

1. Parikh SA, Kay NE, Shanafelt TD. How we treat Richter syndrome. Blood 2014;123:1647-1657.
2. Parikh SA, Rabe KG, Call TG, et al. Diffuse large B-cell lymphoma (Richter syndrome) in patients with chronic lymphocytic leukaemia (CLL): A cohort study of newly diagnosed patients. Br J Haematol 2013;162:774-782.
3. Rossi D, Spina V, Deambrogi C, et al. The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation. Blood 2011;117:3391-3401.
4. Tsimberidou AM, O'Brien S, Khouri I, et al. Clinical outcomes and prognostic factors in patients with Richter's syndrome treated with chemotherapy or chemoimmunotherapy with or without stem-cell transplantation. J Clin Oncol Off J Am Soc Clin Oncol 2006;24:2343-2351.
5. Krause JR, Drinkard LC, Keglovits LC. Hodgkin lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma. Proc Baylor Univ Med Center 2013;26:16-18.
6. Tseng D, Jones CD, Anderson M, et al. Clonally identical Hodgkin's disease develops after allogeneic hematopoietic cell transplant for CLL. Bone Marrow Transplant 2011;46:1576-1578.
7. Vasilj A, Kojic-Katovic S, Maricevic I, et al. Hodgkin's lymphoma variant of Richter's syndrome. Collegium Antropol 2010;34:295-299.
8. Tzankov A, Fong D. Hodgkin's disease variant of Richter's syndrome clonally related to chronic lymphocytic leukemia arises in ZAP-70 negative mutated CLL. Med Hypotheses 2006;66:577-579.
9. Fabbri A, Cencini E, Bocchia M. Hodgkin's lymphoma as Richter's transformation in chronic lymphocytic leukemia. Med Oncol 2014;31:904.
10. Kazmierczak M, Kroll-Balcerzak R, Balcerzak A, et al. Hodgkin lymphoma transformation of chronic lymphocytic leukemia: Cases report and discussion. Med Oncol 2014;31:800.
11. Fayad L, Robertson LE, O'Brien S, et al. Hodgkin's disease variant of Richter's syndrome: Experience at a single institution. Leuk Lymph 1996;23:333-337.
12. Dujardin F, Lefrancq T, Blechet C, et al. Hodgkin's disease variant of Richter's syndrome. Two cases and literature review. Ann Pathol 2008;28:311-316.
13. Jamroziak K, Grzybowska-Izydorczyk O, Jesionek-Kupnicka D, et al. Poor prognosis of Hodgkin variant of Richter transformation in chronic lymphocytic leukemia treated with cladribine. Br J Haematol 2012;158:286-288. author reply 289.
14. Momose H, Jaffe ES, Shin SS, et al. Chronic lymphocytic leukemia/small lymphocytic lymphoma with Reed-Sternberg-like cells and possible transformation to Hodgkin's disease. Mediation by Epstein-Barr virus. Am J Surg Pathol 1992;16:859-867.
15. Tadmor T, Shvidel L, Goldschmidt N, et al. Hodgkin's variant of Richter transformation in chronic lymphocytic leukemia: A retrospective study from the Israeli CLL study group. Anticancer Res 2014;34:785-790.
16. Mao Z, Quintanilla-Martinez L, Raffeld M, et al. IgVH mutational status and clonality analysis of Richter's transformation: Diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution. Am J Surg Pathol 2007;31:1605-1614.
17. Tsimberidou AM, O'Brien S, Kantarjian HM, et al. Hodgkin transformation of chronic lymphocytic leukemia: The M. D. Anderson cancer center experience. Cancer 2006;107:1294-1302.
18. Bockorny B, Codreanu I, Dasanu CA. Hodgkin lymphoma as Richter transformation in chronic lymphocytic leukaemia: A retrospective analysis of world literature. Br J Haematol 2012;156:50-66.
19. Maddocks-Christianson K, Slager SL, Zent CS, et al. Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia. Br J Haematol 2007;139:398-404.
20. Shanafelt TD, Rabe KG, Kay NE, et al. Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia. Cancer 2010;116:4777-4787.
21. Parikh SA, Rabe KG, Kay NE, et al. Chronic lymphocytic leukemia in young (≤55 years) patients: a comprehensive analysis of prognostic factors and outcomes. Haematologica 2014;99(1):140-147.
22. Moccia AA, Donaldson J, Chhanabhai M, et al. International prognostic score in advanced-stage Hodgkin's lymphoma: Altered utility in the modern era. J Clin Oncol Off J Am Soc Clin Oncol 2012;30:3383-3388.
23. Hasenclever D, Diehl V. A prognostic score for advanced Hodgkin's disease. International prognostic factors project on advanced Hodgkin's disease. N Engl J Med 1998;339:1506-1514.
24. Diefenbach C, Li H, Hong F, et al. Evaluation of a novel 3 factor prognostic score (PS-3) for patients with advanced Hodgkin lymphoma (HL) treated on US intergroup E2496. ASH Annual Abstracts 2013; Blood 122 (21): Abstract 4277.
25. Travis LB, Curtis RE, Hankey BF, et al. Second cancers in patients with chronic lymphocytic leukemia. J Natl Cancer Inst 1992;84:1422-1427.
26. Roschewski M, Wilson WH. EBV-associated lymphomas in adults. Best Practice Res Clin Haematol 2012;25:75-89.
27. Available at: www.nccn.org. Hodgkin Lymphoma. NCCN Clinical Guidelines in Oncology: Hodgkin Lymphoma.
28. Younes A, Bartlett NL, Leonard JP, et al. Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas. N Engl J Med 2010;363:1812-1821.
29. Jagadeesh D, Diefenbach C, Evens AM XII. Hodgkin lymphoma in older patients: Challenges and opportunities to improve outcomes. Hematol Oncol 2013;31 (Suppl 1):69-75.
30. Landgren O, Algernon C, Axdorph U, et al. Hodgkin's lymphoma in the elderly with special reference to type and intensity of chemotherapy in relation to prognosis. Haematologica 2003;88:438-444.
31. Evens AM, Helenowski I, Ramsdale E, et al. A retrospective multicenter analysis of elderly Hodgkin lymphoma: Outcomes and prognostic factors in the modern era. Blood 2012;119:692-695.
32. Enblad G, Gustavsson A, Sundstrom C, et al. Patients above sixty years of age with Hodgkin's lymphoma treated with a new strategy. Acta Oncol 2002;41:659-667.