메뉴 건너뛰기




Volumn 35, Issue 12, 2014, Pages 11851-11854

Somatic mutations of the HER2 in metastatic breast cancer

Author keywords

Dimerization; ErbB2; HER2; Phosphorylation; Somatic mutations; Therapeutic antibody

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GENOMIC DNA; TRASTUZUMAB; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; KRAS PROTEIN, HUMAN; MONOCLONAL ANTIBODY; ONCOPROTEIN; RAS PROTEIN;

EID: 84925285811     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2414-y     Document Type: Article
Times cited : (12)

References (17)
  • 1
    • 67649472398 scopus 로고    scopus 로고
    • Novel anticancer targets: revisiting ERBB2 and discovering ERBB3
    • COI: 1:CAS:528:DC%2BD1MXnsVagtbs%3D, PID: 19536107
    • Baselga J, Swain SM. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer. 2009;9(7):463–75.
    • (2009) Nat Rev Cancer , vol.9 , Issue.7 , pp. 463-475
    • Baselga, J.1    Swain, S.M.2
  • 2
    • 0346339584 scopus 로고    scopus 로고
    • Current status and future directions in breast cancer therapy
    • PID: 14667277
    • Hudis CA. Current status and future directions in breast cancer therapy. Clin Breast Cancer. 2003;4 Suppl 2:S70–5.
    • (2003) Clin Breast Cancer , vol.4 , pp. S70-S75
    • Hudis, C.A.1
  • 3
    • 84865165294 scopus 로고    scopus 로고
    • Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling
    • COI: 1:CAS:528:DC%2BC38XhsValtbfL, PID: 22733765
    • Zhang Q et al. Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling. Proc Natl Acad Sci U S A. 2012;109(33):13237–42.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.33 , pp. 13237-13242
    • Zhang, Q.1
  • 4
    • 0037429779 scopus 로고    scopus 로고
    • The deaf and the dumb: the biology of ErbB-2 and ErbB-3
    • COI: 1:CAS:528:DC%2BD3sXitVyltrg%3D, PID: 12648465
    • Citri A, Skaria KB, Yarden Y. The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res. 2003;284(1):54–65.
    • (2003) Exp Cell Res , vol.284 , Issue.1 , pp. 54-65
    • Citri, A.1    Skaria, K.B.2    Yarden, Y.3
  • 5
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment
    • COI: 1:CAS:528:DC%2BD3sXksVahtLs%3D, PID: 12653668
    • Normanno N et al. Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer. 2003;10(1):1–21.
    • (2003) Endocr Relat Cancer , vol.10 , Issue.1 , pp. 1-21
    • Normanno, N.1
  • 6
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • COI: 1:CAS:528:DyaL2sXhtVSht7s%3D, PID: 3798106
    • Slamon DJ et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987;235(4785):177–82.
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1
  • 7
    • 0034787857 scopus 로고    scopus 로고
    • Expression of Her-2/neu in human lung cancer cell lines by immunohistochemistry and fluorescence in situ hybridization and its relationship to in vitro cytotoxicity by trastuzumab and chemotherapeutic agents
    • COI: 1:CAS:528:DC%2BD3MXnvF2rs70%3D, PID: 11595720
    • Bunn PA et al. Expression of Her-2/neu in human lung cancer cell lines by immunohistochemistry and fluorescence in situ hybridization and its relationship to in vitro cytotoxicity by trastuzumab and chemotherapeutic agents. Clin Cancer Res. 2001;7(10):3239–50.
    • (2001) Clin Cancer Res , vol.7 , Issue.10 , pp. 3239-3250
    • Bunn, P.A.1
  • 8
    • 33645130990 scopus 로고    scopus 로고
    • Signaling through ERBB receptors: multiple layers of diversity and control
    • COI: 1:CAS:528:DC%2BD28XivVaktbo%3D, PID: 16460914
    • Warren CM, Landgraf R. Signaling through ERBB receptors: multiple layers of diversity and control. Cell Signal. 2006;18(7):923–33.
    • (2006) Cell Signal , vol.18 , Issue.7 , pp. 923-933
    • Warren, C.M.1    Landgraf, R.2
  • 9
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • COI: 1:CAS:528:DC%2BD38XhsVGmt7o%3D, PID: 11821453
    • Vogel CL et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol. 2002;20(3):719–26.
    • (2002) J Clin Oncol , vol.20 , Issue.3 , pp. 719-726
    • Vogel, C.L.1
  • 10
    • 84969435629 scopus 로고    scopus 로고
    • Molecular mechanisms of trastuzumab resistance
    • Nahta R, Esteva FJ. Molecular mechanisms of trastuzumab resistance. Breast Cancer Res. 2006;8(6):667–74.
    • (2006) Breast Cancer Res , vol.8 , Issue.6 , pp. 667-674
    • Nahta, R.1    Esteva, F.J.2
  • 11
    • 33646712747 scopus 로고    scopus 로고
    • Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer
    • COI: 1:CAS:528:DC%2BD28Xltlagtbg%3D, PID: 16683005
    • Nahta R et al. Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer. Nat Clin Pract Oncol. 2006;3(5):269–80.
    • (2006) Nat Clin Pract Oncol , vol.3 , Issue.5 , pp. 269-280
    • Nahta, R.1
  • 12
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • COI: 1:CAS:528:DC%2BD2MXitV2jsb4%3D, PID: 15741570
    • Shigematsu H et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005;97(5):339–46.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.5 , pp. 339-346
    • Shigematsu, H.1
  • 13
    • 4944232647 scopus 로고    scopus 로고
    • Lung cancer: intragenic ERBB2 kinase mutations in tumours
    • COI: 1:CAS:528:DC%2BD2cXnvFCntLg%3D, PID: 15457249
    • Stephens P et al. Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature. 2004;431(7008):525–6.
    • (2004) Nature , vol.431 , Issue.7008 , pp. 525-526
    • Stephens, P.1
  • 14
    • 0942287963 scopus 로고    scopus 로고
    • Randomized phase II trial of gemcitabine–cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer
    • COI: 1:STN:280:DC%2BD3srps1Kntg%3D%3D, PID: 14679114
    • Gatzemeier U et al. Randomized phase II trial of gemcitabine–cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer. Ann Oncol. 2004;15(1):19–27.
    • (2004) Ann Oncol , vol.15 , Issue.1 , pp. 19-27
    • Gatzemeier, U.1
  • 15
    • 4644274700 scopus 로고    scopus 로고
    • Mutations and addiction to EGFR the Achilles ‘heal’ of lung cancers?
    • COI: 1:CAS:528:DC%2BD2cXotF2is78%3D, PID: 15464447
    • Gazdar AF et al. Mutations and addiction to EGFR: the Achilles ‘heal’ of lung cancers? Trends Mol Med. 2004;10(10):481–6.
    • (2004) Trends Mol Med , vol.10 , Issue.10 , pp. 481-486
    • Gazdar, A.F.1
  • 16
    • 4544302751 scopus 로고    scopus 로고
    • Switching on kinases: oncogenic activation of BRAF and the PDGFR family
    • COI: 1:CAS:528:DC%2BD2cXntFCmtr4%3D, PID: 15343278
    • Dibb NJ, Dilworth SM, Mol CD. Switching on kinases: oncogenic activation of BRAF and the PDGFR family. Nat Rev Cancer. 2004;4(9):718–27.
    • (2004) Nat Rev Cancer , vol.4 , Issue.9 , pp. 718-727
    • Dibb, N.J.1    Dilworth, S.M.2    Mol, C.D.3
  • 17
    • 7444239715 scopus 로고    scopus 로고
    • Targeting ErbB receptor signaling: a pan-ErbB approach to cancer
    • COI: 1:CAS:528:DC%2BD2cXosVSrsLo%3D, PID: 15486201
    • Britten CD. Targeting ErbB receptor signaling: a pan-ErbB approach to cancer. Mol Cancer Ther. 2004;3(10):1335–42.
    • (2004) Mol Cancer Ther , vol.3 , Issue.10 , pp. 1335-1342
    • Britten, C.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.