Altered profile of circulating microparticles in rheumatoid arthritis patients

Clinical Science

Volumn 128, Issue 7, 2015, Pages 437-448

  Rodríguez Carrio, Javier ^a   Alperi López, Mercedes ^b   López, Patricia ^a   Alonso Castro, Sara ^b   Carro Esteban, Santiago R ^a   Ballina García, Francisco J ^b   Suárez, Ana ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

Author keywords

Angiogenic T cell; Cardiovascular risk factor; Endothelial damage; Microparticle; Rheumatoid arthritis

Indexed keywords

ANTIGEN; CD14 ANTIGEN; CD146 ANTIGEN; CD3 ANTIGEN; CD31 ANTIGEN; CD66 ANTIGEN; FIBRINOGEN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ADULT; AGED; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CARDIOVASCULAR RISK; CONTROLLED STUDY; DAS28; DIABETES MELLITUS; DYSLIPIDEMIA; ENDOTHELIUM CELL; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; HYPERTENSION; IMMUNOLOGICAL PARAMETERS; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MEMBRANE MICROPARTICLE; MONOCYTE; OBESITY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; THROMBOCYTE; THROMBOCYTE POOR PLASMA; BLOOD; CARDIOVASCULAR DISEASE; FLOW CYTOMETRY; METABOLISM; MIDDLE AGED; PRINCIPAL COMPONENT ANALYSIS; RISK FACTOR; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; CELL-DERIVED MICROPARTICLES; ENDOTHELIAL CELLS; FEMALE; FLOW CYTOMETRY; GRANULOCYTES; HUMANS; MALE; MIDDLE AGED; MONOCYTES; PRINCIPAL COMPONENT ANALYSIS; RISK FACTORS; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84925282778     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20140675     Document Type: Article

References (53)

1. Beyer, C. and Pisetsky, D. S. (2010) The role of microparticles in the pathogenesis of rheumatic diseases. Nat. Rev. Rheumatol. 6, 21-29
2. Burger, D., Schock, S., Thompson, C. S., Montezano, A. C., Hakim, A. M. and Touyz, R. M. (2013) Microparticles: biomarkers and beyond. Clin. Sci. 124, 423-441
3. Hugel, B., Martinez, M. C., Kunzelmann, C. and Freyssinet, J. M. (2005) Membrane microparticles: two sides of the coin. Physiology 20, 22-27
4. Guiducci, S., Distler, J. H., Jungel, A., Huscher, D., Huber, L. C., Michel, B. A., Gay, R. E., Pisetsky, D. S., Gay, S., Matucci-Cerinic, M. and Distler, O. (2008) The relationship between plasma microparticles and disease manifestations in patients with systemic sclerosis. Arthritis Rheum. 58, 2845-2853
5. Barteneva, N. S., Fasler-Kan, E., Bernimoulin, M., Stern, J. N., Ponomarev, E. D., Duckett, L. and Vorobjev, I. A. (2013) Circulating microparticles: square the circle. BMC Cell Biol. 14, 23
6. Thery, C., Ostrowski, M. and Segura, E. (2009) Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol. 9, 581-593
7. Amabile, N., Heiss, C., Real, W. M., Minasi, P., McGlothlin, D., Rame, E. J., Grossman, W., De, M. T. and Yeghiazarians, Y. (2008) Circulating endothelial microparticle levels predict hemodynamic severity of pulmonary hypertension. Am. J. Respir. Crit. Care Med. 177, 1268-1275
8. Rautou, P. E., Vion, A. C., Amabile, N., Chironi, G., Simon, A., Tedgui, A. and Boulanger, C. M. (2011) Microparticles, vascular function, and atherothrombosis. Circ. Res. 109, 593-606
9. Lee, Y. J., Jy, W., Horstman, L. L., Janania, J., Reyes, Y., Kelley, R. E. and Ahn, Y. S. (1993) Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias. Thromb. Res. 72, 295-304
10. Mesri, M. and Altieri, D. C. (1999) Leukocyte microparticles stimulate endothelial cell cytokine release and tissue factor induction in a JNK1 signaling pathway. J. Biol. Chem. 274, 23111-23118
11. Barry, O. P. and FitzGerald, G. A. (1999) Mechanisms of cellular activation by platelet microparticles. Thromb. Haemost. 82, 794-800
12. Jy, W., Mao, W. W., Horstman, L., Tao, J. and Ahn, Y. S. (1995) Platelet microparticles bind, activate and aggregate neutrophils in vitro. Blood Cells Mol. Dis. 21, 217-231
13. Kambas, K., Chrysanthopoulou, A., Vassilopoulos, D., Apostolidou, E., Skendros, P., Girod, A., Arelaki, S., Froudarakis, M., Nakopoulou, L., Giatromanolaki, A. et al. (2013) Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease. Ann. Rheum. Dis. 73, 1854-1863
14. Gonzalez-Gay, M. A., Gonzalez-Juanatey, C., Lopez-Diaz, M. J., Pineiro, A., Garcia-Porrua, C., Miranda-Filloy, J. A., Ollier, W. E., Martin, J. and Llorca, J. (2007) HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritis. Arthritis Rheum. 57, 125-132
15. Sattar, N., McCarey, D. W., Capell, H. and McInnes, I. B. (2003) Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation 108, 2957-2963
16. Dey-Hazra, E., Hertel, B., Kirsch, T., Woywodt, A., Lovric, S., Haller, H., Haubitz, M. and Erdbruegger, U. (2010) Detection of circulating microparticles by flow cytometry: influence of centrifugation, filtration of buffer, and freezing. Vasc. Health Risk Manag. 6, 1125-1133
17. Connor, D. E., Exner, T., Ma, D. D. and Joseph, J. E. (2010) The majority of circulating platelet-derived microparticles fail to bind annexin V, lack phospholipid-dependent procoagulant activity and demonstrate greater expression of glycoprotein Ib. Thromb. Haemost. 103, 1044-1052
18. Ullal, A. J., Pisetsky, D. S. and Reich, III, C. F. (2010) Use of SYTO 13, a fluorescent dye binding nucleic acids, for the detection of microparticles in in vitro systems. Cytometry A 77, 294-301
19. Nielsen, C. T., Ostergaard, O., Johnsen, C., Jacobsen, S. and Heegaard, N. H. (2011) Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus. Arthritis Rheum. 63, 3067-3077
20. Enjeti, A. K., Lincz, L. F. and Seldon, M. (2007) Detection and measurement of microparticles: an evolving research tool for vascular biology. Semin. Thromb. Hemost. 33, 771-779
21. Rodriguez-Carrio, J., Alperi-Lopez, M., Lopez, P., Alonso-Castro, S., Ballina-Garcia, F. J. and Suarez, A. (2014) Angiogenic T cells are decreased in rheumatoid arthritis patients. Ann. Rheum. Dis., doi: 10.1136/annrheumdis-2013-204250
22. Gonzalez, A., Maradit, K. H., Crowson, C. S., Ballman, K. V., Roger, V. L., Jacobsen, S. J., O'Fallon, W. M. and Gabriel, S. E. (2008) Do cardiovascular risk factors confer the same risk for cardiovascular outcomes in rheumatoid arthritis patients as in non-rheumatoid arthritis patients? Ann. Rheum. Dis. 67, 64-69
23. Rodriguez-Rodriguez, L., Gonzalez-Juanatey, C., Palomino-Morales, R., Vazquez-Rodriguez, T. R., Miranda-Filloy, J. A., Fernandez-Gutierrez, B., Llorca, J., Martin, J. and Gonzalez-Gay, M. A. (2011) TNFA -308 (rs1800629) polymorphism is associated with a higher risk of cardiovascular disease in patients with rheumatoid arthritis. Atherosclerosis 216, 125-130
24. Lacroix, R., Robert, S., Poncelet, P. and Dignat-George, F. (2010) Overcoming limitations of microparticle measurement by flow cytometry. Semin. Thromb. Hemost. 36, 807-818
25. Aass, H. C., Ovstebo, R., Troseid, A. M., Kierulf, P., Berg, J. P. and Henriksson, C. E. (2011) Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis. Cytometry A 79, 990-999
26. Ayers, L., Kohler, M., Harrison, P., Sargent, I., Dragovic, R., Schaap, M., Nieuwland, R., Brooks, S. A. and Ferry, B. (2011) Measurement of circulating cell-derived microparticles by flow cytometry: sources of variability within the assay. Thromb. Res. 127, 370-377
27. Berckmans, R. J., Nieuwland, R., Tak, P. P., Boing, A. N., Romijn, F. P., Kraan, M. C., Breedveld, F. C., Hack, C. E. and Sturk, A. (2002) Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism. Arthritis Rheum. 46, 2857-2866
28. Knijff-Dutmer, E. A., Koerts, J., Nieuwland, R., Kalsbeek-Batenburg, E. M. and van de Laar, M. A. (2002) Elevated levels of platelet microparticles are associated with disease activity in rheumatoid arthritis. Arthritis Rheum. 46, 1498-1503
29. Sellam, J., Proulle, V., Jungel, A., Ittah, M., Miceli, R. C., Gottenberg, J. E., Toti, F., Benessiano, J., Gay, S., Freyssinet, J. M. and Mariette, X. (2009) Increased levels of circulating microparticles in primary Sjogren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity. Arthritis Res. Ther. 11, R156
30. Iversen, L. V., Ostergaard, O., Ullman, S., Nielsen, C. T., Halberg, P., Karlsmark, T., Heegaard, N. H. and Jacobsen, S. (2013) Circulating microparticles and plasma levels of soluble E- and P-selectins in patients with systemic sclerosis. Scand. J. Rheumatol. 42, 473-482
31. Jimenez, J. J., Jy, W., Mauro, L. M., Soderland, C., Horstman, L. L. and Ahn, Y. S. (2003) Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis. Thromb. Res. 109, 175-180
32. Key, N. S. (2010) Analysis of tissue factor positive microparticles. Thromb. Res. 125 (Suppl. 1), S42-S45
33. Szodoray, P., Tarr, T., Tumpek, J., Kappelmayer, J., Lakos, G., Poor, G., Szegedi, G. and Kiss, E. (2009) Identification of rare anti-phospholipid/protein co-factor autoantibodies in patients with systemic lupus erythematosus. Autoimmunity 42, 497-506
34. Albanyan, A. M., Murphy, M. F., Rasmussen, J. T., Heegaard, C. W. and Harrison, P. (2009) Measurement of phosphatidylserine exposure during storage of platelet concentrates using the novel probe lactadherin: a comparison study with annexin V. Transfusion 49, 99-107
35. Bernimoulin, M., Waters, E. K., Foy, M., Steele, B. M., Sullivan, M., Falet, H., Walsh, M. T., Barteneva, N., Geng, J. G., Hartwig, J. H. et al. (2009) Differential stimulation of monocytic cells results in distinct populations of microparticles. J. Thromb. Haemost. 7, 1019-1028
36. Dasgupta, S. K., Abdel-Monem, H., Niravath, P., Le, A., Bellera, R. V., Langlois, K., Nagata, S., Rumbaut, R. E. and Thiagarajan, P. (2009) Lactadherin and clearance of platelet-derived microvesicles. Blood 113, 1332-1339
37. Enjeti, A. K., Lincz, L. and Seldon, M. (2008) Bio-maleimide as a generic stain for detection and quantitation of microparticles. Int. J. Lab. Hematol. 30, 196-199
38. Innala, L., Moller, B., Ljung, L., Magnusson, S., Smedby, T., Sodergren, A., Ohman, M. L., Rantapaa-Dahlqvist, S. and Wallberg-Jonsson, S. (2011) Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study. Arthritis Res. Ther. 13, R131
39. Symmons, D. P. and Gabriel, S. E. (2011) Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE. Nat. Rev. Rheumatol. 7, 399-408
40. Del, R. I., Freeman, G. L., Haas, R. W., O'Leary, D. H. and Escalante, A. (2005) Relative contribution of cardiovascular risk factors and rheumatoid arthritis clinical manifestations to atherosclerosis. Arthritis Rheum. 52, 3413-3423
41. Wallberg-Jonsson, S., Johansson, H., Ohman, M. L. and Rantapaa-Dahlqvist, S. (1999) Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis. A retrospective cohort study from disease onset. J. Rheumatol. 26, 2562-2571
42. Hur, J., Yang, H. M., Yoon, C. H., Lee, C. S., Park, K. W., Kim, J. H., Kim, T. Y., Kim, J. Y., Kang, H. J., Chae, I. H. et al. (2007) Identification of a novel role of T cells in postnatal vasculogenesis: characterization of endothelial progenitor cell colonies. Circulation 116, 1671-1682
43. Ostergaard, O., Nielsen, C. T., Iversen, L. V., Tanassi, J. T., Knudsen, S., Jacobsen, S. and Heegaard, N. H. (2013) Unique protein signature of circulating microparticles in systemic lupus erythematosus. Arthritis Rheum. 65, 2680-2690
44. Gyorgy, B., Szabo, T. G., Turiak, L., Wright, M., Herczeg, P., Ledeczi, Z., Kittel, A., Polgar, A., Toth, K., Derfalvi, B. et al. (2012) Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. PLoS ONE 7, e49726
45. Berckmans, R. J., Nieuwland, R., Kraan, M. C., Schaap, M. C., Pots, D., Smeets, T. J., Sturk, A. and Tak, P. P. (2005) Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes. Arthritis Res. Ther. 7, R536-R544
46. Constans, J. and Conri, C. (2006) Circulating markers of endothelial function in cardiovascular disease. Clin. Chim. Acta 368, 33-47
47. Dessein, P. H., Joffe, B. I. and Singh, S. (2005) Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Arthritis Res. Ther. 7, R634-R643
48. Boulanger, C. M., Scoazec, A., Ebrahimian, T., Henry, P., Mathieu, E., Tedgui, A. and Mallat, Z. (2001) Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction. Circulation 104, 2649-2652
49. Distler, J. H., Akhmetshina, A., Dees, C., Jungel, A., Sturzl, M., Gay, S., Pisetsky, D. S., Schett, G. and Distler, O. (2011) Induction of apoptosis in circulating angiogenic cells by microparticles. Arthritis Rheum. 63, 2067-2077
50. Perez-Casal, M., Downey, C., Fukudome, K., Marx, G. and Toh, C. H. (2005) Activated protein C induces the release of microparticle-associated endothelial protein C receptor. Blood 105, 1515-1522
51. Perez-Casal, M., Downey, C., Cutillas-Moreno, B., Zuzel, M., Fukudome, K. and Toh, C. H. (2009) Microparticle-associated endothelial protein C receptor and the induction of cytoprotective and anti-inflammatory effects. Haematologica 94, 387-394
52. Tans, G., Rosing, J., Thomassen, M. C., Heeb, M. J., Zwaal, R. F. and Griffin, J. H. (1991) Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles. Blood 77, 2641-2648
53. Mesri, M. and Altieri, D. C. (1998) Endothelial cell activation by leukocyte microparticles. J. Immunol. 161, 4382-4387