The offspring of the diabetic mother - Short- and long-term implications

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volumn 29, Issue 2, 2015, Pages 256-269

  Mitanchez, D ^a,e   Yzydorczyk, C ^b   Siddeek, B ^b   Boubred, F ^c   Benahmed, M ^b,d   Simeoni, U ^b  

^a ARMAND TROUSSEAU HOSPITAL   (France)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c Hospital and University Centre   (France)

^d INSERM   (France)

^e SORBONNE UNIVERSITÉ   (France)

Author keywords

breast feeding; cardiovascular diseases; gestational diabetes; hypoglycemia; macrosomia; obesity; pregnancy

Indexed keywords

BREAST FEEDING; CARDIOVASCULAR DISEASE; FEMALE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; HYPOCALCEMIA; HYPOGLYCEMIA; KIDNEY DISEASE; LOWEST INCOME GROUP; MACROSOMIA; MATERNAL DIABETES MELLITUS; META ANALYSIS; NEONATAL HYPERBILIRUBINEMIA; NEONATAL HYPOCALCEMIA; NEONATAL HYPOGLYCEMIA; NEONATAL POLYCYTHEMIA; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEWBORN DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PANDEMIC; PERINATAL DEATH; POLYCYTHEMIA; PREGNANCY; PREMATURE LABOR; PRENATAL EXPOSURE; PRENATAL GROWTH; PRIORITY JOURNAL; PROGENY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW; CARDIOVASCULAR DISEASES; DEVELOPED COUNTRY; DIABETES MELLITUS, TYPE 2; HEALTH DISPARITY; INFANT, NEWBORN, DISEASES; KIDNEY DISEASES; NEWBORN; PREGNANCY DIABETES MELLITUS; RISK FACTOR;

CARDIOVASCULAR DISEASES; DEVELOPED COUNTRIES; DIABETES MELLITUS, TYPE 2; DIABETES, GESTATIONAL; FEMALE; HEALTH STATUS DISPARITIES; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; KIDNEY DISEASES; OBESITY; PREGNANCY; PREGNANCY IN DIABETICS; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS;

EID: 84925270965     PISSN: 15216934     EISSN: 15321932     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2014.08.004     Document Type: Article

References (100)

1. V. Anna, H.P. van der Ploeg, and N.W. Cheung Sociodemographic correlates of the increasing trend in prevalence of gestational diabetes mellitus in a large population of women between 1995 and 2005 Diabetes Care 31 2008 2288 2293
2. U. Simeoni, and D.J. Barker Offspring of diabetic pregnancy: long-term outcomes Semin Fetal Neonatal Med 14 2009 119 124
3. D. Mitanchez Foetal and neonatal complications in gestational diabetes: perinatal mortality, congenital malformations, macrosomia, shoulder dystocia, birth injuries, neonatal complications Diabetes Metab 36 2010 617 627
4. D. Mitanchez Management of infants born to mothers with gestational diabetes. Paediatric environment Diabetes Metab 36 2010 587 594
5. K. Horvath, K. Koch, and K. Jeitler Effects of treatment in women with gestational diabetes mellitus: systematic review and meta-analysis Bmj 340 2010 c1395
6. M. Falavigna, M.I. Schmidt, and J. Trujillo Effectiveness of gestational diabetes treatment: a systematic review with quality of evidence assessment Diabetes Res Clin Pract 98 2012 396 405
7. D. Mitanchez, A. Burguet, and U. Simeoni Infants born to mothers with gestational diabetes mellitus: mild neonatal effects, a long-term threat to global health J Pediatr 164 2014 445 450
8. D.J. Barker Intrauterine programming of adult disease Mol Med Today 1 1995 418 423
9. S.Y. Chu, W.M. Callaghan, and S.Y. Kim Maternal obesity and risk of gestational diabetes mellitus Diabetes Care 30 2007 2070 2076
10. R. Bell, K. Bailey, and T. Cresswell Trends in prevalence and outcomes of pregnancy in women with pre-existing type I and type II diabetes Bjog 115 2008 445 452
11. T. Henriksen The macrosomic fetus: a challenge in current obstetrics Acta Obstet Gynecol Scand 87 2008 134 145
12. J. Pedersen Weight and length at birth of infants of diabetic mothers Acta Endocrinol (Copenh) 16 1954 330 342
13. B.E. Metzger, L.P. Lowe, and A.R. Dyer Hyperglycemia and adverse pregnancy outcomes N Engl J Med 358 2008 1991 2002
14. P.M. Catalano, and S. Hauguel-De Mouzon Is it time to revisit the Pedersen hypothesis in the face of the obesity epidemic? Am J Obstet Gynecol 204 2011 479 487
15. T. Radaelli, J. Lepercq, and A. Varastehpour Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus Am J Obstet Gynecol 201 2009 209 e201-209 e210
16. T. Radaelli, A. Varastehpour, and P. Catalano Gestational diabetes induces placental genes for chronic stress and inflammatory pathways Diabetes 52 2003 2951 2958
17. A.A. Houde, M.F. Hivert, and L. Bouchard Fetal epigenetic programming of adipokines Adipocyte 2 2013 41 46
18. Z. Yu, S. Han, and J. Zhu Pre-pregnancy body mass index in relation to infant birth weight and offspring overweight/obesity: a systematic review and meta-analysis PLoS One 8 2013 e61627
19. M.F. Sewell, L. Huston-Presley, and D.M. Super Increased neonatal fat mass, not lean body mass, is associated with maternal obesity Am J Obstet Gynecol 195 2006 1100 1103
20. J.A. Hutcheon, R.W. Platt, and S.J. Meltzer Is birth weight modified during pregnancy? Using sibling differences to understand the impact of blood glucose, obesity, and maternal weight gain in gestational diabetes Am J Obstet Gynecol 195 2006 488 494
21. S. Alberico, M. Montico, and V. Barresi The role of gestational diabetes, pre-pregnancy body mass index and gestational weight gain on the risk of newborn macrosomia: results from a prospective multicentre study BMC Pregnancy Childbirth 14 2014 23
22. Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: associations with neonatal anthropometrics Diabetes 58 2009 453 459
23. I.M. Evers, H.W. de Valk, and B.W. Mol Macrosomia despite good glycaemic control in Type I diabetic pregnancy; results of a nationwide study in The Netherlands Diabetologia 45 2002 1484 1489
24. A. Lapolla, M.G. Dalfra, and D. Fedele Pregnancy complicated by type 2 diabetes: an emerging problem Diabetes Res Clin Pract 80 2008 2 7
25. M. Balsells, A. Garcia-Patterson, and I. Gich Maternal and fetal outcome in women with type 2 versus type 1 diabetes mellitus: a systematic review and metaanalysis J Clin Endocrinol Metab 94 2009 4284 4291
26. X. Zhang, A. Decker, and R.W. Platt How big is too big? the perinatal consequences of fetal macrosomia Am J Obstet Gynecol 198 517 2008 e511 516
27. A. Weissmann-Brenner, M.J. Simchen, and E. Zilberberg Maternal and neonatal outcomes of large for gestational age pregnancies Acta Obstet Gynecol Scand 91 2012 844 849
28. G. Evans-Jones, S.P. Kay, and A.M. Weindling Congenital brachial palsy: incidence, causes, and outcome in the United Kingdom and Republic of Ireland Arch Dis Child Fetal Neonatal Ed 88 2003 F185 F189
29. A. Weindling Offspring of diabetic pregnancy: short term outcomes Semin Fetal Neonatal Med 14 2009 111 118
30. E.A. Reece Diabetes-induced birth defects: what do we know? what can we do? Curr Diab Rep 12 2012 24 32
31. L. McLeod, and J.G. Ray Prevention and detection of diabetic embryopathy Community Genet 5 2002 33 39
32. M.C. Macintosh, K.M. Fleming, and J.A. Bailey Perinatal mortality and congenital anomalies in babies of women with type 1 or type 2 diabetes in England, Wales, and Northern Ireland: population based study BMJ 333 2006 177
33. M. Balsells, A. Garcia-Patterson, and I. Gich Major congenital malformations in women with gestational diabetes mellitus: a systematic review and meta-analysis Diabetes Metab Res Rev 28 2012 252 257
34. D.J. Schneider, and J.W. Moore Patent ductus arteriosus Circulation 114 2006 1873 1882
35. T.I. Chang, M. Horal, and S.K. Jain Oxidant regulation of gene expression and neural tube development: insights gained from diabetic pregnancy on molecular causes of neural tube defects Diabetologia 46 2003 538 545
36. Z. Zhao, P. Yang, and R.L. Eckert Caspase-8: a key role in the pathogenesis of diabetic embryopathy Birth Defects Res B Dev Reprod Toxicol 86 2009 72 77
37. D.J. Dudley Diabetic-associated stillbirth: incidence, pathophysiology, and prevention Obstet Gynecol Clin North Am 34 2007 293 307 [ix]
38. T. Cundy, G. Gamble, and K. Townend Perinatal mortality in Type 2 diabetes mellitus Diabet Med 17 2000 33 39
39. E.R. Mathiesen, L. Ringholm, and P. Damm Stillbirth in diabetic pregnancies Best Pract Res Clin Obstet Gynaecol 25 2011 105 111
40. S. Ullmo, Y. Vial, and S. Di Bernardo Pathologic ventricular hypertrophy in the offspring of diabetic mothers: a retrospective study Eur Heart J 28 2007 1319 1325
41. J. Garcia-Flores, M. Janez, and M.C. Gonzalez Fetal myocardial morphological and functional changes associated with well-controlled gestational diabetes Eur J Obstet Gynecol Reprod Biol 154 2011 24 26
42. C. Chu, Y.H. Gui, and Y.Y. Ren The impacts of maternal gestational diabetes mellitus (GDM) on fetal hearts Biomed Environ Sci 25 2012 15 22
43. A. Vambergue, and I. Fajardy Consequences of gestational and pregestational diabetes on placental function and birth weight World J Diabetes 2 2011 196 203
44. S.V. Glinianaia, P.W. Tennant, and R.W. Bilous HbA(1c) and birthweight in women with pre-conception type 1 and type 2 diabetes: a population-based cohort study Diabetologia 55 2012 3193 3203
45. J. Yang, E.A. Cummings, and C. O'Connell Fetal and neonatal outcomes of diabetic pregnancies Obstet Gynecol 108 2006 644 650
46. N.L. Gonzalez-Gonzalez, O. Ramirez, and J. Mozas Factors influencing pregnancy outcome in women with type 2 versus type 1 diabetes mellitus Acta Obstet Gynecol Scand 87 2008 43 49
47. M.M. Hedderson, A. Ferrara, and D.A. Sacks Gestational diabetes mellitus and lesser degrees of pregnancy hyperglycemia: association with increased risk of spontaneous preterm birth Obstet Gynecol 102 2003 850 856
48. Y. Yogev, and O. Langer Spontaneous preterm delivery and gestational diabetes: the impact of glycemic control Arch Gynecol Obstet 276 2007 361 365
49. J.M. Piper, E.M. Xenakis, and O. Langer Delayed appearance of pulmonary maturation markers is associated with poor glucose control in diabetic pregnancies J Matern Fetal Med 7 1998 148 153
50. T.R. Moore A comparison of amniotic fluid fetal pulmonary phospholipids in normal and diabetic pregnancy Am J Obstet Gynecol 186 2002 641 650
51. H.M. Salihu, H.E. Weldeselasse, and K. Rao The impact of obesity on maternal morbidity and feto-infant outcomes among macrosomic infants J Matern Fetal Neonatal Med 24 2011 1088 1094
52. B.E. Metzger, B. Persson, and L.P. Lowe Hyperglycemia and adverse pregnancy outcome study: neonatal glycemia Pediatrics 126 2010 e1545 1552
53. S. Demarini, F. Mimouni, and R.C. Tsang Impact of metabolic control of diabetes during pregnancy on neonatal hypocalcemia: a randomized study Obstet Gynecol 83 1994 918 922
54. M. Alzaim, and R.J. Wood Vitamin D and gestational diabetes mellitus Nutr Rev 71 2013 158 167
55. D. Dabelea, and D.J. Pettitt Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility J Pediatr Endocrinol Metab 14 2001 1085 1091
56. D. Dabelea The predisposition to obesity and diabetes in offspring of diabetic mothers Diabetes Care 30 Suppl. 2 2007 S169 S174
57. D. Dabelea, R.L. Hanson, and R.S. Lindsay Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships Diabetes 49 2000 2208 2211
58. M.W. Gillman, S. Rifas-Shiman, and C.S. Berkey Maternal gestational diabetes, birth weight, and adolescent obesity Pediatrics 111 2003 e221 226
59. D.A. Lawlor, P. Lichtenstein, and N. Langstrom Association of maternal diabetes mellitus in pregnancy with offspring adiposity into early adulthood: sibling study in a prospective cohort of 280,866 men from 248,293 families Circulation 123 2011 258 265
60. D. Dabelea, E.J. Mayer-Davis, and A.P. Lamichhane Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study Diabetes Care 31 2008 1422 1426
61. S.Y. Kim, J.L. England, and J.A. Sharma Gestational diabetes mellitus and risk of childhood overweight and obesity in offspring: a systematic review Exp Diabetes Res 2011 2011 541308
62. L.H. Philipps, S. Santhakumaran, and C. Gale The diabetic pregnancy and offspring BMI in childhood: a systematic review and meta-analysis Diabetologia 54 2011 1957 1966
63. N.A. West, T.L. Crume, and M.A. Maligie Cardiovascular risk factors in children exposed to maternal diabetes in utero Diabetologia 54 2011 504 507
64. J.C. Bunt, P.A. Tataranni, and A.D. Salbe Intrauterine exposure to diabetes is a determinant of hemoglobin A(1)c and systolic blood pressure in pima Indian children J Clin Endocrinol Metab 90 2005 3225 3229
65. A. Aceti, S. Santhakumaran, and K.M. Logan The diabetic pregnancy and offspring blood pressure in childhood: a systematic review and meta-analysis Diabetologia 55 2012 3114 3127
66. S. Taddei, A. Virdis, and P. Mattei Endothelium-dependent forearm vasodilation is reduced in normotensive subjects with familial history of hypertension J Cardiovasc Pharmacol 20 Suppl. 12 1992 S193 S195
67. D.A. Ingram, I.Z. Lien, and L.E. Mead In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony-forming cell numbers and function Diabetes 57 2008 724 731
68. E.K. Blue, R. DiGiuseppe, and E. Derr-Yellin Gestational diabetes induces alterations in the function of neonatal endothelial colony-forming cells Pediatr Res 75 2014 266 272
69. T. Kobayashi, T. Nogami, and K. Taguchi Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK Br J Pharmacol 155 2008 974 983
70. Y.F. Bian, H.Y. Yang, and Z.M. Yang Amlodipine treatment prevents angiotensin II-induced human umbilical vein endothelial cell apoptosis Arch Med Res 42 2011 22 27
71. F. Zhang, X. Xiao, and D. Liu Increased cord blood angiotensin II concentration is associated with decreased insulin sensitivity in the offspring of mothers with gestational diabetes mellitus J Perinatol 33 2013 9 14
72. R.C. Atkins, and P. Zimmet Diabetic kidney disease: act now or pay later Acta Diabetol 47 2010 1 4
73. R.G. Nelson, H. Morgenstern, and P.H. Bennett Intrauterine diabetes exposure and the risk of renal disease in diabetic Pima Indians Diabetes 47 1998 1489 1493
74. M. Kinalski, A. Sledziewski, and B. Telejko Lipid peroxidation, antioxidant defence and acid-base status in cord blood at birth: the influence of diabetes Horm Metab Res 33 2001 227 231
75. J. Xu, J. Ye, and Y. Wu Reduced fetal telomere length in gestational diabetes PLoS One 9 2014 e86161
76. C. Yzydorczyk, F. Gobeil Jr., and G. Cambonie Exaggerated vasomotor response to ANG II in rats with fetal programming of hypertension associated with exposure to a low-protein diet during gestation Am J Physiol Regul Integr Comp Physiol 291 2006 R1060 R1068
77. J. Abe, and B.C. Berk Reactive oxygen species as mediators of signal transduction in cardiovascular disease Trends Cardiovasc Med 8 1998 59 64
78. L. Monasta, G.D. Batty, and A. Cattaneo Early-life determinants of overweight and obesity: a review of systematic reviews Obes Rev 11 2010 695 708
79. C.M. Boney, A. Verma, and R. Tucker Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus Pediatrics 115 2005 e290 296
80. P. Hovi, S. Andersson, and J.G. Eriksson Glucose regulation in young adults with very low birth weight N Engl J Med 356 2007 2053 2063
81. P.L. Hofman, F. Regan, and W.E. Jackson Premature birth and later insulin resistance N Engl J Med 351 2004 2179 2186
82. J. Rotteveel, M.M. van Weissenbruch, and J.W. Twisk Infant and childhood growth patterns, insulin sensitivity, and blood pressure in prematurely born young adults Pediatrics 122 2008 313 321
83. K. Pilgaard, K. Faerch, and B. Carstensen Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes Diabetologia 53 2010 2526 2530
84. C. Crump, M.A. Winkleby, and K. Sundquist Risk of diabetes among young adults born preterm in Sweden Diabetes Care 34 2011 1109 1113
85. K. Poplawska, K. Dudek, and M. Koziarz Prematurity-related hypertension in children and adolescents Int J Pediatr 2012 2012 537936
86. P.F. Vassallo, S. Simoncini, and I. Ligi Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression Blood 2014
87. I. Ligi, S. Simoncini, and E. Tellier A switch toward angiostatic gene expression impairs the angiogenic properties of endothelial progenitor cells in low birth weight preterm infants Blood 118 2011 1699 1709
88. I. Ligi, S. Simoncini, and E. Tellier Altered angiogenesis in low birth weight individuals: a role for anti-angiogenic circulating factors J Matern Fetal Neonatal Med 27 2014 233 238
89. T. Harder, R. Bergmann, and G. Kallischnigg Duration of breastfeeding and risk of overweight: a meta-analysis Am J Epidemiol 162 2005 397 403
90. A. Singhal, and J. Lanigan Breastfeeding, early growth and later obesity Obes Rev 8 Suppl. 1 2007 51 54
91. N. Stettler, V.A. Stallings, and A.B. Troxel Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula Circulation 111 2005 1897 1903
92. C. Druet, N. Stettler, and S. Sharp Prediction of childhood obesity by infancy weight gain: an individual-level meta-analysis Paediatr Perinat Epidemiol 26 2012 19 26
93. T.L. Crume, L. Ogden, and M. Maligie Long-term impact of neonatal breastfeeding on childhood adiposity and fat distribution among children exposed to diabetes in utero Diabetes Care 34 2011 641 645
94. T.L. Crume, L.G. Ogden, and E.J. Mayer-Davis The impact of neonatal breast-feeding on growth trajectories of youth exposed and unexposed to diabetes in utero: the EPOCH Study Int J Obes (Lond) 36 2012 529 534
95. E.J. Mayer-Davis, S.L. Rifas-Shiman, and L. Zhou Breast-feeding and risk for childhood obesity: does maternal diabetes or obesity status matter? Diabetes Care 29 2006 2231 2237
96. D.J. Pettitt, and W.C. Knowler Long-term effects of the intrauterine environment, birth weight, and breast-feeding in Pima Indians Diabetes Care 21 Suppl. 2 1998 B138 B141
97. A. Singhal, T.J. Cole, and M. Fewtrell Breastmilk feeding and lipoprotein profile in adolescents born preterm: follow-up of a prospective randomised study Lancet 363 2004 1571 1578
98. L. Guariguata Contribute data to the 6th edition of the IDF Diabetes Atlas Diabetes Res Clin Pract 100 2013 280 281
99. V. Seshiah, V. Balaji, and M.S. Balaji Pregnancy and diabetes scenario around the world: India Int J Gynaecol Obstet 104 Suppl. 1 2009 S35 S38
100. A. Koyanagi, J. Zhang, and A. Dagvadorj Macrosomia in 23 developing countries: an analysis of a multicountry, facility-based, cross-sectional survey Lancet 381 2013 476 483