Evaluating vaccination strategies for reducing infant respiratory syncytial virus infection in low-income settings

BMC Medicine

Volumn 13, Issue 1, 2015, Pages

  Poletti, Piero ^a,b   Merler, Stefano ^b   Ajelli, Marco ^b   Manfredi, Piero ^c   Munywoki, Patrick K ^d   James Nokes, D ^d,e   Melegaro, Alessia ^a  

^a BOCCONI UNIVERSITY   (Italy)

^b FONDAZIONE BRUNO KESSLER   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Computational models; Household transmission; Infectious diseases; RSV; Vaccination

Indexed keywords

AGE DISTRIBUTION; ANTIBODY RESPONSE; ARTICLE; CHILD; CHILD CARE; CONTROLLED STUDY; DATA ANALYSIS; DRUG EFFICACY; ELEMENTARY STUDENT; EPIDEMIC; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INCIDENCE; INFECTION RESISTANCE; INFECTION SENSITIVITY; LOWEST INCOME GROUP; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; MOTHER FETUS RELATIONSHIP; NONHUMAN; POPULATION RESEARCH; POPULATION STRUCTURE; PRENATAL CARE; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RISK ASSESSMENT; RISK REDUCTION; RURAL POPULATION; SCHOOL CHILD; VACCINATION; VIRUS TRANSMISSION; ADOLESCENT; DEVELOPING COUNTRY; FEMALE; INFANT; KENYA; MALE; POVERTY; PREGNANCY; PRESCHOOL CHILD; PREVENTIVE HEALTH SERVICE; PROCEDURES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; TRANSMISSION;

RESPIRATORY SYNCYTIAL VIRUS VACCINE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DEVELOPING COUNTRIES; FEMALE; HUMANS; IMMUNIZATION PROGRAMS; INFANT; KENYA; MALE; POVERTY; PREGNANCY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS VACCINES; RURAL POPULATION;

EID: 84925233920     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-015-0283-x     Document Type: Article

References (38)

1. Waris M. Pattern of respiratory syncytial virus epidemics in Finland: two-year cycles with alternating prevalence of groups A and B. J Infect Dis. 1991; 163:464-9.
2. Mlinaric-Galinovic G, Welliver RC, Vilibic-Cavlek T, Ljubin-Sternak S, Drazenovic V, Galinovic I, et al. The biennial cycle of respiratory syncytial virus outbreaks in Croatia. Virol J. 2008; 5:18.
3. Nokes DJ, Okiro EA, Ngama M, Ochola R, White LJ, Scott PD, et al. Respiratory syncytial virus infection and disease in infants and young children observed from birth in Kilifi District, Kenya. Clin Infect Dis. 2008; 46:50-7.
4. Ohuma EO, Okiro EA, Ochola R, Sande CJ, Cane PA, Medley GF, et al. The natural history of respiratory syncytial virus in a birth cohort: the influence of age and previous infection on reinfection and disease. Am J Epidemiol. 2012; 176:794-802.
5. Nokes DJ, Ngama M, Bett A, Abwao J, Munywoki PK, English M, et al. Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance. Clin Infect Dis. 2009; 49:1341-9.
6. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010; 375:1545-55.
7. Berkley JA, Munywoki P, Ngama M, Kazungu S, Abwao J, Bett A, et al. Viral etiology of severe pneumonia among Kenyan infants and children. J Am Med Assoc. 2010; 303:2051-7.
8. Glezen WP, Taber LH, Frank AL, Kasel JA. Risk of primary infection and reinfection with respiratory syncytial virus. Am J Dis Child. 1986; 140:543-6.
9. Hall CB, Geiman JM, Biggar R, Kotok DI, Hogan PM, Douglas RG. Respiratory syncytial virus infections within families. N Engl J Med. 1976; 294:414-41.
10. Hall CB, Weinberg GA, Iwane MK, Blumkin AK, Edwards KM, Staat MA, et al. The burden of respiratory syncytial virus infection in young children. N Engl J Med. 2009; 360:588-98.
11. Okiro EA, White LJ, Ngama M, Cane PA, Medley GF, Nokes DJ. Duration of shedding of respiratory syncytial virus in a community study of Kenyan children. BMC Infect Dis. 2010; 10:15.
12. Fletcher JN, Smyth RL, Thomas HM, Ashby D, Hart CA. Respiratory syncytial virus genotypes and disease severity among children in hospital. Arch Dis Child. 1997; 77:508-11.
13. Polack FP, Karron RA. The future of respiratory syncytial virus vaccine development. Pediatr Infect Dis J. 2004; 23:65-73.
14. Anderson LJ, Dormitzer PR, Nokes DJ, Rappuoli R, Roca A, Graham BS. Strategic priorities for respiratory syncytial virus (RSV) vaccine development. Vaccine. 2013; 31:209-15.
15. Munywoki PK, Koech DC, Agoti CN, Lewa C, Cane PA, Medley GF, et al.The source of respiratory syncytial virus infection in infants: a household cohort study in rural Kenya. J Infect Dis. 2013; 209(10):1685-1692.
16. Ferguson NM, Cummings DAT, Cauchemez S, Fraser C, Riley S, Meeyai A, et al. Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature. 2005; 437:209-14.
17. Merler S, Ajelli M. The role of population heterogeneity and human mobility in the spread of pandemic influenza. Proc R Soc B. 2010; 277(1681):557-65.
18. Merler S, Ajelli M, Pugliese A, Ferguson NM. Determinants of the spatiotemporal dynamics of the 2009 H1N1 pandemic in Europe: implications for real-time modelling. PLOS Comput Biol. 2011; 7:1002205.
19. Merler S, Ajelli M, Fumanelli L, Vespignani A. Containing the accidental laboratory escape of potential pandemic influenza viruses. BMC Med. 2013; 11(3):252.
20. The DHS Program, Demographic and Health Surveys. http://dhsprogram.com/data/.
21. Kenya Open Data. https://opendata.go.ke/.
22. United Nations, Department of Economic and Social Affairs. World Population Prospects. http://www.un.org/en/development/desa/population/.
23. Gomes MGM, White LJ, Medley GF. Infection, reinfection, and vaccination under suboptimal immune protection: epidemiological perspectives. J Theor Biol. 2004; 228:539-49.
24. Weber A, Weber M, Milligan P. Modeling epidemics caused by respiratory syncytial virus (RSV). Math Biosci. 2001; 172:95-113.
25. White LJ, Mandl NJ, Gomes MGM, Bodely-Tickell AT, Cane PA, Perez-Brena P, et al. Understanding the transmission dynamics of respiratory syncytial virus using multiple time series and nested models. Math Biosci. 2007; 209:222-39.
26. Ochola R, Sande C, Fegan G, Scott PD, Medley GF, Cane PA, et al. The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya. PLOS ONE. 2009; 4:8088.
27. Munywoki PK, Koech DC, Agoti CN, Kibirige N, Kipoech J, Cane PA, et al. Influence of age, severity of infection, and co-infection on the duration of respiratory syncytial virus (RSV) shedding. Epidemiol Infect. 2014. http://dx.doi.org/10.1017/S0950268814001393.
28. UNESCO, International Bureau of Education. http://www.ibe.unesco.org/.
29. Cauchemez S, Carrat F, Viboud C, Valleron AJ, Boëlle PY. A Bayesian MCMC approach to study transmission of influenza: application to household longitudinal data. Stat Med. 2004; 23:3469-87.
30. Merler S, Ajelli M. Deciphering the relative weights of demographic transition and vaccination in the descrease of measles incidence in Italy. Proc R Soc B. 2014; 281:20132676.
31. Nokes DJ, Okiro EA, Ngama M, White LJ, Ochola R, Scott PD, et al. Respiratory syncytial virus epidemiology in a birth cohort from Kilifi District, Kenya: infection during the first year of life. J Infect Dis. 2004; 190:1828-32.
32. Baguelin M, Flasche S, Camacho A, Demiris N, Miller E, Edmunds WJ. Assessing optimal target populations for influenza vaccination programmes: an evidence synthesis and modelling study. PLOS Med. 2013; 10:1001527.
33. PATH's Work in Vaccine Development. http://sites.path.org/vaccinedevelopment/.
34. Glezen WP, Paredes A, Allison JE, Taber LH, Frank AL. Risk of respiratory syncytial virus infection for infants from low-income families in relationship to age, sex, ethnic group, and maternal antibody level. J Pediatr. 1981; 98:708-15.
35. Ferguson NM, Cummings DAT, Fraser C, Cajka JC, Cooley PC, Burke DS. Strategies for mitigating an influenza pandemic. Nature. 2006; 442:448-52.
36. Ajelli M, Merler S. The impact of the unstructured contacts component in influenza pandemic modeling. PLOS ONE. 2008; 3:1519.
37. Graham BS. Protecting the family to protect the child: vaccination strategy guided by RSV transmission dynamics. J Infect Dis. 2014; 209:1679-81.
38. d'Onofrio A, Manfredi P, Poletti P. The interplay of public intervention and private choices in determining the outcome of vaccination programmes. PLOS ONE. 2012; 7:45653.