메뉴 건너뛰기




Volumn 73, Issue 2, 2015, Pages 245-252

Low serum interleukin-6 levels as a predictive marker of recurrence in patients with hepatitis B virus related hepatocellular carcinoma who underwent curative treatment

Author keywords

Cytokine; Hepatitis B, chronic; Hepatocellular carcinoma; Prognosis

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; SERUM ALBUMIN; TUMOR NECROSIS FACTOR ALPHA; IL6 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84925201192     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2015.02.027     Document Type: Article
Times cited : (15)

References (46)
  • 1
    • 84890904585 scopus 로고    scopus 로고
    • Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection
    • Lu T., Seto W.K., Zhu R.X., Lai C.L., Yuen M.F. Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection. World J Gastroenterol 2013, 19:8887-8894.
    • (2013) World J Gastroenterol , vol.19 , pp. 8887-8894
    • Lu, T.1    Seto, W.K.2    Zhu, R.X.3    Lai, C.L.4    Yuen, M.F.5
  • 2
    • 79952231921 scopus 로고    scopus 로고
    • American association for the study of liver, diseases. Management of hepatocellular carcinoma: an update
    • Bruix J., Sherman M. American association for the study of liver, diseases. Management of hepatocellular carcinoma: an update. Hepatology 2011, 53:1020-1022.
    • (2011) Hepatology , vol.53 , pp. 1020-1022
    • Bruix, J.1    Sherman, M.2
  • 3
    • 84896849610 scopus 로고    scopus 로고
    • Treatment options and surveillance strategies after therapy for hepatocellular carcinoma
    • Hatzaras I., Bischof D.A., Fahy B., Cosgrove D., Pawlik T.M. Treatment options and surveillance strategies after therapy for hepatocellular carcinoma. Ann Surg Oncol 2014, 21:758-766.
    • (2014) Ann Surg Oncol , vol.21 , pp. 758-766
    • Hatzaras, I.1    Bischof, D.A.2    Fahy, B.3    Cosgrove, D.4    Pawlik, T.M.5
  • 4
    • 79960748644 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma
    • Tiong L., Maddern G.J. Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma. Br J Surg 2011, 98:1210-1224.
    • (2011) Br J Surg , vol.98 , pp. 1210-1224
    • Tiong, L.1    Maddern, G.J.2
  • 5
    • 31844436517 scopus 로고    scopus 로고
    • Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications
    • Portolani N., Coniglio A., Ghidoni S., Giovanelli M., Benetti A., Tiberio G.A., et al. Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications. Ann Surg 2006, 243:229-235.
    • (2006) Ann Surg , vol.243 , pp. 229-235
    • Portolani, N.1    Coniglio, A.2    Ghidoni, S.3    Giovanelli, M.4    Benetti, A.5    Tiberio, G.A.6
  • 6
    • 0038460305 scopus 로고    scopus 로고
    • Liver resection for hepatocellular carcinoma on cirrhosis: univariate and multivariate analysis of risk factors for intrahepatic recurrence
    • Ercolani G., Grazi G.L., Ravaioli M., Del Gaudio M., Gardini A., Cescon M., et al. Liver resection for hepatocellular carcinoma on cirrhosis: univariate and multivariate analysis of risk factors for intrahepatic recurrence. Ann Surg 2003, 237:536-543.
    • (2003) Ann Surg , vol.237 , pp. 536-543
    • Ercolani, G.1    Grazi, G.L.2    Ravaioli, M.3    Del Gaudio, M.4    Gardini, A.5    Cescon, M.6
  • 7
    • 84867982366 scopus 로고    scopus 로고
    • Serum interleukin-6 and C-reactive protein as a prognostic indicator in hepatocellular carcinoma
    • Jang J.W., Oh B.S., Kwon J.H., You C.R., Chung K.W., Kay C.S., et al. Serum interleukin-6 and C-reactive protein as a prognostic indicator in hepatocellular carcinoma. Cytokine 2012, 60:686-693.
    • (2012) Cytokine , vol.60 , pp. 686-693
    • Jang, J.W.1    Oh, B.S.2    Kwon, J.H.3    You, C.R.4    Chung, K.W.5    Kay, C.S.6
  • 8
    • 33747029250 scopus 로고    scopus 로고
    • Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
    • Budhu A., Forgues M., Ye Q.H., Jia H.L., He P., Zanetti K.A., et al. Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 2006, 10:99-111.
    • (2006) Cancer Cell , vol.10 , pp. 99-111
    • Budhu, A.1    Forgues, M.2    Ye, Q.H.3    Jia, H.L.4    He, P.5    Zanetti, K.A.6
  • 9
    • 84864651241 scopus 로고    scopus 로고
    • A study of circulating interleukin 10 in prognostication of unresectable hepatocellular carcinoma
    • Chan S.L., Mo F.K., Wong C.S., Chan C.M., Leung L.K., Hui E.P., et al. A study of circulating interleukin 10 in prognostication of unresectable hepatocellular carcinoma. Cancer 2012, 118:3984-3992.
    • (2012) Cancer , vol.118 , pp. 3984-3992
    • Chan, S.L.1    Mo, F.K.2    Wong, C.S.3    Chan, C.M.4    Leung, L.K.5    Hui, E.P.6
  • 11
    • 84887572063 scopus 로고    scopus 로고
    • The blood neutrophil-to-lymphocyte ratio predicts survival in patients with advanced hepatocellular carcinoma receiving sorafenib
    • Zheng Y.B., Zhao W., Liu B., Lu L.G., He X., Huang J.W., et al. The blood neutrophil-to-lymphocyte ratio predicts survival in patients with advanced hepatocellular carcinoma receiving sorafenib. Asian Pac J Cancer Prev 2013, 14:5527-5531.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 5527-5531
    • Zheng, Y.B.1    Zhao, W.2    Liu, B.3    Lu, L.G.4    He, X.5    Huang, J.W.6
  • 12
    • 34249900712 scopus 로고    scopus 로고
    • High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies
    • Poon R.T., Lau C., Pang R., Ng K.K., Yuen J., Fan S.T. High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies. Ann Surg Oncol 2007, 14:1835-1845.
    • (2007) Ann Surg Oncol , vol.14 , pp. 1835-1845
    • Poon, R.T.1    Lau, C.2    Pang, R.3    Ng, K.K.4    Yuen, J.5    Fan, S.T.6
  • 13
    • 84870591777 scopus 로고    scopus 로고
    • Diagnosis: novel prognostic biomarkers in hepatocellular carcinoma
    • Pang R.W., Poon R.T. Diagnosis: novel prognostic biomarkers in hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol 2012, 9:691-692.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 691-692
    • Pang, R.W.1    Poon, R.T.2
  • 14
    • 84859433790 scopus 로고    scopus 로고
    • Molecular and serum markers in hepatocellular carcinoma: predictive tools for prognosis and recurrence
    • Singhal A., Jayaraman M., Dhanasekaran D.N., Kohli V. Molecular and serum markers in hepatocellular carcinoma: predictive tools for prognosis and recurrence. Crit Rev Oncol Hematol 2012, 82:116-140.
    • (2012) Crit Rev Oncol Hematol , vol.82 , pp. 116-140
    • Singhal, A.1    Jayaraman, M.2    Dhanasekaran, D.N.3    Kohli, V.4
  • 15
    • 0023989527 scopus 로고
    • Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21
    • Ferguson-Smith A.C., Chen Y.F., Newman M.S., May L.T., Sehgal P.B., Ruddle F.H. Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21. Genomics 1988, 2:203-208.
    • (1988) Genomics , vol.2 , pp. 203-208
    • Ferguson-Smith, A.C.1    Chen, Y.F.2    Newman, M.S.3    May, L.T.4    Sehgal, P.B.5    Ruddle, F.H.6
  • 16
    • 42649129014 scopus 로고    scopus 로고
    • Systematic review of the association between circulating interleukin-6 (IL-6) and cancer
    • Heikkila K., Ebrahim S., Lawlor D.A. Systematic review of the association between circulating interleukin-6 (IL-6) and cancer. Eur J Cancer 2008, 44:937-945.
    • (2008) Eur J Cancer , vol.44 , pp. 937-945
    • Heikkila, K.1    Ebrahim, S.2    Lawlor, D.A.3
  • 17
    • 84973466704 scopus 로고    scopus 로고
    • IL-6, a promising tumor marker and prognostic indicator in patients with HCC?
    • Kinoshita A., Nishino H. IL-6, a promising tumor marker and prognostic indicator in patients with HCC?. J Tumor 2014, 2:142-144.
    • (2014) J Tumor , vol.2 , pp. 142-144
    • Kinoshita, A.1    Nishino, H.2
  • 19
    • 79952523091 scopus 로고    scopus 로고
    • IL-6-174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma
    • Giannitrapani L., Soresi M., Giacalone A., Campagna M.E., Marasa M., Cervello M., et al. IL-6-174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma. OMICS 2011, 15:183-186.
    • (2011) OMICS , vol.15 , pp. 183-186
    • Giannitrapani, L.1    Soresi, M.2    Giacalone, A.3    Campagna, M.E.4    Marasa, M.5    Cervello, M.6
  • 20
    • 0028027039 scopus 로고
    • Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis
    • Ueda T., Shimada E., Urakawa T. Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis. J Gastroenterol 1994, 29:423-429.
    • (1994) J Gastroenterol , vol.29 , pp. 423-429
    • Ueda, T.1    Shimada, E.2    Urakawa, T.3
  • 21
    • 0026625812 scopus 로고
    • Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma
    • Blay J.Y., Negrier S., Combaret V., Attali S., Goillot E., Merrouche Y., et al. Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma. Cancer Res 1992, 52:3317-3322.
    • (1992) Cancer Res , vol.52 , pp. 3317-3322
    • Blay, J.Y.1    Negrier, S.2    Combaret, V.3    Attali, S.4    Goillot, E.5    Merrouche, Y.6
  • 23
    • 84871781976 scopus 로고    scopus 로고
    • APASL and AASLD consensus guidelines on imaging diagnosis of hepatocellular carcinoma: a review
    • Tan C.H., Low S.C., Thng C.H. APASL and AASLD consensus guidelines on imaging diagnosis of hepatocellular carcinoma: a review. Int J Hepatol 2011, 2011:519783.
    • (2011) Int J Hepatol , vol.2011 , pp. 519783
    • Tan, C.H.1    Low, S.C.2    Thng, C.H.3
  • 24
    • 34247498645 scopus 로고    scopus 로고
    • Validation of clinical AJCC/UICC TNM staging system for hepatocellular carcinoma: analysis of 5,613 cases from a medical center in southern Taiwan
    • Kee K.M., Wang J.H., Lee C.M., Chen C.L., Changchien C.S., Hu T.H., et al. Validation of clinical AJCC/UICC TNM staging system for hepatocellular carcinoma: analysis of 5,613 cases from a medical center in southern Taiwan. Int J Cancer 2007, 120:2650-2655.
    • (2007) Int J Cancer , vol.120 , pp. 2650-2655
    • Kee, K.M.1    Wang, J.H.2    Lee, C.M.3    Chen, C.L.4    Changchien, C.S.5    Hu, T.H.6
  • 27
    • 84925121452 scopus 로고    scopus 로고
    • Serum levels of interleukin-6 and interleukin-10 as biomarkers for hepatocellular carcinoma in Egyptian patients
    • Othman M.S., Aref A.M., Mohamed A.A., Ibrahim W.A. Serum levels of interleukin-6 and interleukin-10 as biomarkers for hepatocellular carcinoma in Egyptian patients. ISRN Hepatol 2013, 2013:1-9.
    • (2013) ISRN Hepatol , vol.2013 , pp. 1-9
    • Othman, M.S.1    Aref, A.M.2    Mohamed, A.A.3    Ibrahim, W.A.4
  • 28
    • 83355174169 scopus 로고    scopus 로고
    • Preoperative levels of serum interleukin-6 in patients with hepatocellular carcinoma
    • Pang X.H., Zhang J.P., Zhang Y.J., Yan J., Pei X.Q., Zhang Y.Q., et al. Preoperative levels of serum interleukin-6 in patients with hepatocellular carcinoma. Hepatogastroenterology 2011, 58:1687-1693.
    • (2011) Hepatogastroenterology , vol.58 , pp. 1687-1693
    • Pang, X.H.1    Zhang, J.P.2    Zhang, Y.J.3    Yan, J.4    Pei, X.Q.5    Zhang, Y.Q.6
  • 29
    • 43049147317 scopus 로고    scopus 로고
    • Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway
    • Moran D.M., Mattocks M.A., Cahill P.A., Koniaris L.G., McKillop I.H. Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway. J Surg Res 2008, 147:23-33.
    • (2008) J Surg Res , vol.147 , pp. 23-33
    • Moran, D.M.1    Mattocks, M.A.2    Cahill, P.A.3    Koniaris, L.G.4    McKillop, I.H.5
  • 30
    • 17044384183 scopus 로고    scopus 로고
    • Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma
    • Moran D.M., Mayes N., Koniaris L.G., Cahill P.A., McKillop I.H. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. Liver Int 2005, 25:445-457.
    • (2005) Liver Int , vol.25 , pp. 445-457
    • Moran, D.M.1    Mayes, N.2    Koniaris, L.G.3    Cahill, P.A.4    McKillop, I.H.5
  • 31
    • 0034721080 scopus 로고    scopus 로고
    • Oncostatin M and interleukin 6 inhibit cell cycle progression by prevention of p27kip1 degradation in HepG2 cells
    • Klausen P., Pedersen L., Jurlander J., Baumann H. Oncostatin M and interleukin 6 inhibit cell cycle progression by prevention of p27kip1 degradation in HepG2 cells. Oncogene 2000, 19:3675-3683.
    • (2000) Oncogene , vol.19 , pp. 3675-3683
    • Klausen, P.1    Pedersen, L.2    Jurlander, J.3    Baumann, H.4
  • 32
    • 0032788884 scopus 로고    scopus 로고
    • Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells
    • Kim H., Baumann H. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells. Mol Cell Biol 1999, 19:5326-5338.
    • (1999) Mol Cell Biol , vol.19 , pp. 5326-5338
    • Kim, H.1    Baumann, H.2
  • 33
    • 84879513296 scopus 로고    scopus 로고
    • Circulating IL-6, IL-17 and vitamin D in hepatocellular carcinoma: potential biomarkers for a more favorable prognosis?
    • Hammad L.N., Abdelraouf S.M., Hassanein F.S., Mohamed W.A., Schaalan M.F. Circulating IL-6, IL-17 and vitamin D in hepatocellular carcinoma: potential biomarkers for a more favorable prognosis?. J Immunotoxicol 2013, 10:380-386.
    • (2013) J Immunotoxicol , vol.10 , pp. 380-386
    • Hammad, L.N.1    Abdelraouf, S.M.2    Hassanein, F.S.3    Mohamed, W.A.4    Schaalan, M.F.5
  • 34
    • 84885671431 scopus 로고    scopus 로고
    • Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling
    • He G., Dhar D., Nakagawa H., Font-Burgada J., Ogata H., Jiang Y., et al. Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell 2013, 155:384-396.
    • (2013) Cell , vol.155 , pp. 384-396
    • He, G.1    Dhar, D.2    Nakagawa, H.3    Font-Burgada, J.4    Ogata, H.5    Jiang, Y.6
  • 35
    • 84859586321 scopus 로고    scopus 로고
    • Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors
    • quiz 78
    • Shiina S., Tateishi R., Arano T., Uchino K., Enooku K., Nakagawa H., et al. Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors. Am J Gastroenterol 2012, 107:569-577. quiz 78.
    • (2012) Am J Gastroenterol , vol.107 , pp. 569-577
    • Shiina, S.1    Tateishi, R.2    Arano, T.3    Uchino, K.4    Enooku, K.5    Nakagawa, H.6
  • 36
    • 0036189906 scopus 로고    scopus 로고
    • Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: implications for a strategy of salvage transplantation
    • Poon R.T., Fan S.T., Lo C.M., Liu C.L., Wong J. Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: implications for a strategy of salvage transplantation. Ann Surg 2002, 235:373-382.
    • (2002) Ann Surg , vol.235 , pp. 373-382
    • Poon, R.T.1    Fan, S.T.2    Lo, C.M.3    Liu, C.L.4    Wong, J.5
  • 37
    • 0033809358 scopus 로고    scopus 로고
    • Survival and recurrence after hepatic resection of 386 consecutive patients with hepatocellular carcinoma
    • Hanazaki K., Kajikawa S., Shimozawa N., Mihara M., Shimada K., Hiraguri M., et al. Survival and recurrence after hepatic resection of 386 consecutive patients with hepatocellular carcinoma. J Am Coll Surg 2000, 191:381-388.
    • (2000) J Am Coll Surg , vol.191 , pp. 381-388
    • Hanazaki, K.1    Kajikawa, S.2    Shimozawa, N.3    Mihara, M.4    Shimada, K.5    Hiraguri, M.6
  • 38
    • 31544451057 scopus 로고    scopus 로고
    • Correlations between serum monocyte chemotactic protein-1 levels, clinical prognostic factors, and HER-2/neu vaccine-related immunity in breast cancer patients
    • Dehqanzada Z.A., Storrer C.E., Hueman M.T., Foley R.J., Harris K.A., Jama Y.H., et al. Correlations between serum monocyte chemotactic protein-1 levels, clinical prognostic factors, and HER-2/neu vaccine-related immunity in breast cancer patients. Clin Cancer Res 2006, 12:478-486.
    • (2006) Clin Cancer Res , vol.12 , pp. 478-486
    • Dehqanzada, Z.A.1    Storrer, C.E.2    Hueman, M.T.3    Foley, R.J.4    Harris, K.A.5    Jama, Y.H.6
  • 39
    • 33744736009 scopus 로고    scopus 로고
    • Interleukin-10 polymorphisms, cancer susceptibility and prognosis
    • Howell W.M., Rose-Zerilli M.J. Interleukin-10 polymorphisms, cancer susceptibility and prognosis. Fam Cancer 2006, 5:143-149.
    • (2006) Fam Cancer , vol.5 , pp. 143-149
    • Howell, W.M.1    Rose-Zerilli, M.J.2
  • 40
    • 84908867157 scopus 로고    scopus 로고
    • Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance
    • Ganapathi S.K., Beggs A.D., Hodgson S.V., Kumar D. Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance. Br J Cancer 2014, 111:1581-1589.
    • (2014) Br J Cancer , vol.111 , pp. 1581-1589
    • Ganapathi, S.K.1    Beggs, A.D.2    Hodgson, S.V.3    Kumar, D.4
  • 42
    • 84862161008 scopus 로고    scopus 로고
    • Analysis of the risk factors for early death due to disease recurrence or progression within 1 year after hepatectomy in patients with hepatocellular carcinoma
    • Kamiyama T., Nakanishi K., Yokoo H., Kamachi H., Tahara M., Kakisaka T., et al. Analysis of the risk factors for early death due to disease recurrence or progression within 1 year after hepatectomy in patients with hepatocellular carcinoma. World J Surg Oncol 2012, 10:107.
    • (2012) World J Surg Oncol , vol.10 , pp. 107
    • Kamiyama, T.1    Nakanishi, K.2    Yokoo, H.3    Kamachi, H.4    Tahara, M.5    Kakisaka, T.6
  • 43
    • 84868641794 scopus 로고    scopus 로고
    • Association between nucleoside analogues and risk of hepatitis B virus-related hepatocellular carcinoma recurrence following liver resection
    • Wu C.Y., Chen Y.J., Ho H.J., Hsu Y.C., Kuo K.N., Wu M.S., et al. Association between nucleoside analogues and risk of hepatitis B virus-related hepatocellular carcinoma recurrence following liver resection. JAMA 2012, 308:1906-1914.
    • (2012) JAMA , vol.308 , pp. 1906-1914
    • Wu, C.Y.1    Chen, Y.J.2    Ho, H.J.3    Hsu, Y.C.4    Kuo, K.N.5    Wu, M.S.6
  • 44
    • 79955571589 scopus 로고    scopus 로고
    • Risk factors for long-term prognosis in hepatocellular carcinoma after radiofrequency ablation therapy: the clinical implication of aspartate aminotransferase-platelet ratio index
    • Kao W.Y., Chiou Y.Y., Hung H.H., Chou Y.H., Su C.W., Wu J.C., et al. Risk factors for long-term prognosis in hepatocellular carcinoma after radiofrequency ablation therapy: the clinical implication of aspartate aminotransferase-platelet ratio index. Eur J Gastroenterol Hepatol 2011, 23:528-536.
    • (2011) Eur J Gastroenterol Hepatol , vol.23 , pp. 528-536
    • Kao, W.Y.1    Chiou, Y.Y.2    Hung, H.H.3    Chou, Y.H.4    Su, C.W.5    Wu, J.C.6
  • 45
    • 0034028927 scopus 로고    scopus 로고
    • Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma
    • Chau G.Y., Wu C.W., Lui W.Y., Chang T.J., Kao H.L., Wu L.H., et al. Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma. Ann Surg 2000, 231:552-558.
    • (2000) Ann Surg , vol.231 , pp. 552-558
    • Chau, G.Y.1    Wu, C.W.2    Lui, W.Y.3    Chang, T.J.4    Kao, H.L.5    Wu, L.H.6
  • 46
    • 84873895841 scopus 로고    scopus 로고
    • IL-6 upregulation contributes to the reduction of miR-26a expression in hepatocellular carcinoma cells
    • Zhang Y., Zhang B., Zhang A., Li X., Liu J., Zhao J., et al. IL-6 upregulation contributes to the reduction of miR-26a expression in hepatocellular carcinoma cells. Braz J Med Biol Res 2013, 46:32-38.
    • (2013) Braz J Med Biol Res , vol.46 , pp. 32-38
    • Zhang, Y.1    Zhang, B.2    Zhang, A.3    Li, X.4    Liu, J.5    Zhao, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.