Burden and determinants of severe anemia among HIV-infected adults: Results from a large urban HIV Program in Tanzania, East Africa

Journal of the International Association of Providers of AIDS Care

Volumn 14, Issue 2, 2015, Pages 148-155

  Makubi, Abel ^a,b   Okuma, James ^c   Spiegelman, Donna ^c   Hawkins, Claudia ^b,d   Darling, Anne Marie ^c   Jackson, Elizabeth ^c   Mugusi, Ferdinand ^a,b   Chalamilla, Guerino ^b,c   Fawzi, Wafaie ^b,c  

^a MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^b MANAGEMENT AND DEVELOPMENT FOR HEALTH   (Tanzania)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

adults; burden; determinants; HIV; severe anemia

Indexed keywords

COTRIMOXAZOLE; HEMOGLOBIN;

ADOLESCENT; ADULT; AGED; ANEMIA; ARTICLE; BODY MASS; CHRONIC DIARRHEA; CROSS-SECTIONAL STUDY; DISEASE CLASSIFICATION; FEMALE; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; KAPOSI SARCOMA; MAJOR CLINICAL STUDY; MALE; MICROCYTIC ANEMIA; MIDDLE AGED; MULTIVARIATE ANALYSIS; NORMOCYTIC ANEMIA; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; TANZANIA; UNIVARIATE ANALYSIS; CHILD; COMPLICATION; HEALTH; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANEMIA; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PREVALENCE; TANZANIA; URBAN HEALTH; YOUNG ADULT;

EID: 84925197534     PISSN: 23259574     EISSN: 23259582     Source Type: Journal    
DOI: 10.1177/2325957413488195     Document Type: Article

References (30)

1. Fangman JJ, Scadden DT. Anemia in HIV-infected adults: epidemiology, pathogenesis and clinical management. Curr Hematol Rep. 2005 ; 4 (2). 95-96
2. O'Brien ME, Kupka R, Msamanga GI, Saathoff E, Hunter DJ, Fawzi WW. Anemia is an independent predictor of mortality and immunological progression of disease among women with HIV in Tanzania. J Acquir Immune Defic Syndr. 2005 ; 40 (2). 219-220
3. Volberding PA, Levine AM, Dieterich D, Mildvan D, Mitsuyasu R, Saag M.. Anemia in HIV Infection: Clinical Impact and evidence-based management strategies. Clin Infect Dis. 2004 ; 38 (10). 1454-1457
4. Sullivan PS, Hanson DL, Chu SY, Jones JL, Ward JW. Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the multistate adult and adolescent spectrum of HIV disease surveillance project. Blood. 1998 ; 91 (1). 301-308
5. Zhou J, Jaquet A, Bissagnene E, et al. Short-term risk of anaemia following initiation of combination antiretroviral treatment in HIV- infected patients in countries in sub-Saharan Africa, Asia-Pacific, and central and South America. J Int AIDS Soc. 2012 ; 15 (1). 5
6. Johannessen A, Naman E, Gundersen SG, Bruun JN. Antiretroviral treatment reverses HIV-associated anemia in rural Tanzania. BMC Infect Dis. 2011 ; 11: 190
7. Wills TS, Nadler JP, Somboonwit C, et al. Anemia prevalence and associated risk factors in a single-center ambulatory HIV clinical cohort. AIDS Read. 2004 ; 14 (6). 305-310
8. Adesina O, Oladokun A, Akinyemi O, Akingbola T, Awolude O, Adewole I. Risk of anaemia in HIV positive pregnant women in Ibadan, south west Nigeria. Afr J Med Med Sci. 2011 ; 40 (1). 67-73
9. Okechukwu A, Gambo D, Okechukwu O.. Prevalence of anaemia in HIV-infected children at the University of Abuja Teaching Hospital, Gwagwalada. Niger J Med. 2010 ; 19 (1). 50-57
10. Johnnessen A, Naman E, Ngowi B, et al. Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania. BMC Infect Dis. 2008 ; 8: 52
11. Mugisha JO, Shafer LA, Van der Paal L, et al. Anemia in a rural Ugandan HIV cohort: prevalence at enrolment, incidence, diagnosis and associated factors. Trop Med Int Health. 2008 ; 13 (6). 788-794
12. Lewis SM, Bain BJ, Bates I. Dacie and Lewis Practical Hematology. 10 th ed. London, UK: Churchill Livingstone Elservier; 2010:133, 162-163, 206. London, UK: Churchill Livingstone Elservier ; 2010: 162-163.
13. Nyesigire R E, Bajunirwe F, Kiwanuka J. Anaemia in HIV-infected children: severity, types and effect on response to HAART. BMC Pediatr. 2012 ; 12: 170
14. Mary Lynn R, Sutin D Geriatric Medicine and Gerontology. London, UK: Churchill Livingstone, Edinburg ; 2003: 1229-1123.
15. Massawe SN, Urassa EN, Mmari M, et al. The complexity of pregnanc anemia in Dar-es-Salaam. Gynecol Obstet Invest. 47 (2). 76-82
16. Wacholder S. Binomial regression in GLIM: estimating risk ratios and risk differences. Am J Epidemiol. 1986 ; 123 (1). 174-184
17. Skov T, Deddens J, Petersen MR, Endahl L. Prevalence proportion ratios: estimation and hypothesis testing. Int J Epidemiol. 1998 ; 27 (1). 91-95
18. Spiegelman D, Hertzmark E. Easy SAS calculations for risk or prevalence ratios and differences. Am J Epidemiol. 2005 ; 162 (3). 199-200
19. Miettinen OS Theoretical Epidemiology. New York, NY: Wiley ; 1985 :
20. Smith M, Patricia L.. Splines as a useful and convenient statistical tool. Am Stat. 1979 ; 33 (2). 57
21. Harrell M, Frank E, Lee J, et al. Regression models in clinical studies: determining relationships between predictors and response. J Natl Cancer Inst. 1998 ; 80 (15). 1198-1202
22. Mocroft A, Kirk O, Barton SE, et al. Anemia is an independent predictive marker for clinical prognosis in HIV-infected patients from across Europe. AIDS. 1999 ; 13 (8). 943-950
23. Cartmell E, Natalal H, Francois I, et al. Nutritional and clinical status of children admitted to the malnutrition ward, Maputo central hospital: a comparison of data from 2001 and 1983. J Trop Pediatr. 2005 ; 51 (2). 102-105
24. Tatala S, Svanberg U, Mduma B. Low dietary iron availability is a major cause of anemia: a nutrition survey in the Lindi District of Tanzania. Am J Clin Nutr. 1998 ; 68 (1). 171-178
25. Simpore J, Zongo F, Kabore F, et al. Nutrition rehabilitation of HIV-infected and HIV-negative undernourished adults utilizing spirulina. Ann Nutr Metab. 2005 ; 49 (6). 373-380
26. Semba RD, Shah N, Klein RS, et al. Prevalence and cumulative incidence of and risk factors for anemia in a multicenter cohort study of human immunodeficiency virus-infected and -uninfected women. Clin Infect Dis. 2002 ; 34 (2). 260-266
27. Subbaraman R, Devaleenal B, Selvamuthu P, et al. Factors associated with anemia in HIV-infected individuals in southern India. Int J STD AIDS. 2009 ; 20 (7). 489-492
28. Ngowi BJ, Mfinanga SG, Bruun JN, Morkve O. Pulmonary tuberculosis among people living with HIV/AIDS attending care and treatment in rural northern Tanzania. BMC Public Health. 2008 ; 8: 341
29. Calis JC, Phiri KS, Faragher EB, et al. Severe anemia in Malawian adults. N Engl J Med. 2008 ; 358 (9). 888-899
30. Lee SW, Kang YA, Yoon YS, et al. The prevalence and evolution of anemia in patients with tuberculosis. J Korean Med Sci. 2006 ; 21 (6). 1028-1033