Anaemia in HIV-infected children: Severity, types and effect on response to HAART

BMC Pediatrics

Volumn 12, Issue , 2012, Pages

  Nyesigire Ruhinda, Eunice ^a   Bajunirwe, Francis ^a   Kiwanuka, Julius ^a  

^a University of Science and Technology   (Uganda)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; COTRIMOXAZOLE; EFAVIRENZ; HEMOGLOBIN; LAMIVUDINE; NEVIRAPINE; RIFAMPICIN; STAVUDINE; ZIDOVUDINE;

ADOLESCENT; ADULT; ANEMIA; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; COHORT ANALYSIS; DISEASE SEVERITY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; SCHOOL CHILD; TUBERCULOSIS; VIRUS LOAD;

ADOLESCENT; ANEMIA; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HIV INFECTIONS; HIV-1; HUMANS; INFANT; LAMIVUDINE; LOGISTIC MODELS; MALE; NEVIRAPINE; PREVALENCE; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; UGANDA; ZIDOVUDINE;

EID: 84868249973     PISSN: None     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-12-170     Document Type: Article

References (26)

1. Revicki DA, Brown RE, Henry DH, McNeill MV, Rios A, Watson T. Recombinant human erythropoietin and health-related quality of life of AIDS patients with anemia. J Acquir Immune Defic Syndr 1994, 7:474-484.
2. Cleeland CS, Demeri GD, Glapsy J. Identifying haemoglobin level for optimal quality of life: results of an incremental analysis [Abstract] 1999, American Society of Clinical Oncology, Meeting Abstract No: 2215.
3. Volberding PA. The impact of anaemia on quality of life in human immunodeficiency virus-infected patients. J Infect Dis 2002, 185(suppl 2):S110-S114.
4. Kreuzer KA, Rockstroh JK. Pathogenesis and pathophysiology of anaemia in HIV infection. Ann Hematol 1997, 75:179-187. 10.1007/s002770050340, 9433373.
5. Calis CJ, Van Boele Hensbroek M, De Haan RJ, Moons P, Brabin BJ, Imelda B. HIV-associated anaemia in children: a systematic review from a global perspective. AIDS 2008, 22:1099-1112. 10.1097/QAD.0b013e3282fa759f, 18525255.
6. Clark TD, Mmiro F, Ndugwa C, Perry RT, Jackson JB, Melikian G. Risk factors and cumulative incidence of anaemia among human immunodeficiency virus-infected children in Uganda. Ann Trop Paediatr 2002, 22:11-17. 10.1179/027249302125000102, 11926044.
7. Sullivan P, Hanson DL, Chu SY, Jones JL, Ward JW. Epidemiology of anaemia in HIV-infected persons: results from a multistate adult and adolescent spectrum of the HIV disease surveillance project. Blood 1998, 91:301-308.
8. Morfeldt-Manson L, Bottiger B, Nilsson B, von Stedingk LV. Clinical signs and laboratory markers in predicting progression to AIDS in HIV-1 infected patients. Scand J Infect Dis 1991, 23:443-449. 10.3109/00365549109075092, 1683492.
9. Moore RD, Keruly, Jeanne C, Chaisson, Richard E. Anaemia and survival in HIV infection. JAIDS 1998, 19(1):29-33.
10. Creagh T, Mildvan D, Bohn H, Moore R, Ray L. A case-control study to examine the association of HIV/AIDS progression with the development and treatment of anaemia: results from 1996 enrolment cohort, [Poster presentation]. Program and abstracts of the 1st IAS Conference on HIV Pathogenesis and Treatment 2001, Buenos Aires, Abstract No. 318.
11. Raphael WL, Ssemwanga D, Alash'le A, Ndembi N. Update on HIV-1 diversity in Africa: a decade in review. AIDS Rev 2012, 14:83-100.
12. Beckman Coulter Counter, Inc Fullerton CA, USA https://www.beckmancoulter.com/wsrportal/wsr/diagnostics/clinical-products/hematology/coulter-act-5diff-cp/index.htm/coulter-act-5diff-cp/index.htm, Beckman Coulter Counter, Inc Fullerton CA, USA.
13. Dacie J, Lewis S. Basic Haematological Techniques. Practical haematology 2006, 36-40. London: Churchill Livingstone, Barbara JB, Mitchell LS, Imelda B, 10th.
14. Heiserma DL. Manual Cell Counts, Blood Specimens. Methods of hematology 2004, SweetHaven Publishing Services, Part V.
15. Becton Dickinson, NJ, USA http://www.bdbiosciences.com/instruments/facscalibur/index.jsp, Becton Dickinson, NJ, USA.
16. Roche Diagnostics, Indiana, USA http://molecular.roche.com/instruments/Pages/COBASAMPLICORAnalyzer.aspx, Roche Diagnostics, Indiana, USA.
17. World Health Organization When start ART in infants and children. Antiretroviral therapy of HIV infection in infants and children in resource-limited settings: Towards universal access 2006, Geneva, Part V:14, World Health Organization.
18. World Health Organization Haemoglobin levels to diagnose anaemia at sea level. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity 2001, 3. Geneva, World Health Organization.
19. Eley BS, Sive AA, Margaret S, Hussey GD. A prospective, cross-sectional study of anaemia and peripheral iron status in antiretroviral naïve HIV-1 infected children in Cape Town, South Africa. BMC Infect Dis 2002, 2:3. 10.1186/1471-2334-2-3, 65689, 11866864.
20. Silva EB, Grotto HZW, Vilela MMS. Clinical aspects and complete blood counts in children exposed to HIV-1: comparison between infected patients and seroreverters. J Pediatr (Rio J) 2001, 77(6):503-511.
21. Tsiakalos A, Kordossis T, Ziakas PD, Kontos A, Kyriaki D, Sipsas NV. Circulating antibodies to endogenous erythropoietin and risk for HIV-1- related anemia. J Infect 2010, 60:238-243. 10.1016/j.jinf.2009.12.013, 20036688.
22. World Health Organization Revised WHO clinical staging of HIV/AIDS for infants and children. Interim World Health Organization Clinical staging of HIV/AIDS and HIV/AIDS case definitions for surveillance: African region 2005, 11-12. Geneva, World Health Organization.
23. Mocroft A, Kirk O, Barton SE, Dietrich M, Proenca R, Colebunders R, Pradier C, Monforte A, Arminioh L, Brunoi L, Jens DB. Anaemia is an independent predictive marker for clinical prognosis in HIV-infected patients from across Europe. AIDS 1999, 13(8):943-950. 28, 10.1097/00002030-199905280-00010, 10371175.
24. Musoke PM, Mudiope P, Barlow-Mosha LN, Ajuna P, Bagenda D, Mubiru MM, Tylleskar T, Fowler MG. Growth, immune and viral responses in HIV infected African children receiving highly active antiretroviral therapy: a prospective cohort study. BMC Pediatr 2010, 10:56. 10.1186/1471-2431-10-56, 2923128, 20691045.
25. Puthanakit T, Kerr SJ, Ananworanich J, Bunupuradah T, Boonrak P, Sirisanthana T. Pattern and predictors of immunologic recovery in human immunodeficiency virus-infected children receiving non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy. Pediatr Infect Dis J 2009, 28(6):488-492. 10.1097/INF.0b013e318194eea6, 19504731.
26. Sullivan P, Buskin S. Early diagnosis and appropriate treatment of HIV-related anemia important to survival of the HIV-positive. The body Pro covers 2003, The 2nd international AIDS society conference on HIV pathogenesis and treatment, Poster 1154.