Circulating IGF-1 may mediate improvements in haemoglobin associated with vitamin A status during pregnancy in rural Nepalese women

Asia Pacific Journal of Clinical Nutrition

Volumn 24, Issue 1, 2015, Pages 128-137

  Arguello, Margia A ^a   Schulze, Kerry J ^a   Wu, Lee S F ^a   Dreyfuss, Michele L ^a   Khatry, Subarna K ^b   Christian, Parul ^a   West, Keith P ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Nepal Nutrition Intervention Project Sarlahi   (Nepal)

Author keywords

Anaemia; Haemoglobin; Insulin like growth factor 1; Pregnancy; Vitamin A

Indexed keywords

BETA CAROTENE; FERRITIN; HEMOGLOBIN; IRON; IRON INTAKE; RETINOL; SOMATOMEDIN C;

ADMINISTRATION AND DOSAGE; ADULT; ANEMIA; BLOOD; COMPLICATION; CONTROLLED STUDY; DIETARY SUPPLEMENT; DOUBLE BLIND PROCEDURE; ERYTHROPOIESIS; FEMALE; GESTATIONAL AGE; HUMAN; IRON INTAKE; NEPAL; NUTRITIONAL STATUS; PHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATION; RANDOMIZED CONTROLLED TRIAL; RETINOL DEFICIENCY; RURAL POPULATION; YOUNG ADULT;

ADULT; ANEMIA; BETA CAROTENE; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; ERYTHROPOIESIS; FEMALE; FERRITINS; GESTATIONAL AGE; HEMOGLOBINS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; IRON; IRON, DIETARY; NEPAL; NUTRITIONAL STATUS; PREGNANCY; PREGNANCY COMPLICATIONS; RURAL POPULATION; VITAMIN A; VITAMIN A DEFICIENCY; YOUNG ADULT;

EID: 84925157687     PISSN: 09647058     EISSN: None     Source Type: Journal    
DOI: 10.6133/apjcn.2015.24.1.12     Document Type: Article

References (45)

1. WHO. Global prevalence of vitamin A deficiency in populations at risk 1995-2005. WHO Global Database on Vitamin A Deficiency. Geneva: World Health Organization; 2009.
2. West KP Jr, Katz J, Khatry SK, LeClerq SC, Pradhan EK, Shrestha SR et al. Double blind, cluster randomised trial of low dose supplementation with vitamin A or beta carotene on mortality related to pregnancy in Nepal. The NNIPS-2 Study Group. BMJ. 1999;318:570-5. doi: 10.1136/bmj.318.7183.570.
3. Christian P, West KP Jr, Khatry SK, Kimbrough-Pradhan E, LeClerq SC, Katz J, Shrestha SR, Dali SM, Sommer A. Night blindness during pregnancy and subsequent mortality among women in Nepal: effects of vitamin A and betacarotene supplementation. Am J Epidemiol. 2000;152:542-7. doi: 10.1093/aje/152.6.542.
4. Christian P, West KP Jr, Khatry SK, Katz J, LeClerq SC, Kimbrough-Pradhan E, Dali SM, Shrestha SR. Vitamin A or beta-carotene supplementation reduces symptoms of illness in pregnant and lactating Nepali women. J Nutr. 2000;130:2675-82.
5. Dreyfuss ML. Anemia and iron deficiency during pregnancy: etiologies and effects on birth outcomes in Nepal [dissertation]. Baltimore (MD): Johns Hopkins University School of Public Health; 1998.
6. WHO. Global prevalence of anaemia 1993-2005. WHO global database on anaemia. Geneva: World Health Organization; 2008.
7. West KJ, Gernand A, Sommer A. Vitamin A in nutritional anemia. In: Kramer M, Zimmermann MB, editors. Nutritional Anemia. Basel, Switzerland: SIGHT AND LIFE Press; 2007. pp.133-153.
8. Semba RD, Bloem MW. The anemia of vitamin A deficiency: epidemiology and pathogenesis. Eur J Clin Nutr. 2002;56:271-81. doi: 10.1038/sj.ejcn.1601320.
9. Brugnara C. Iron deficiency and erythropoiesis: new diagnostic approaches. Clin Chem. 2003;49:1573-8. doi: 10.1373/49.10.1573.
10. Ratajczak J, Zhang Q, Pertusini E, Wojczyk BS, Wasik MA, Ratajczak MZ. The role of insulin (INS) and insulin-like growth factor-I (IGF-I) in regulating human erythropoiesis. Studies in vitro under serum-free conditions--comparison to other cytokines and growth factors. Leukemia. 1998;12:371-81. doi: 10.1038/sj.leu.2400927.
11. Aron DC. Insulin-like growth factor I and erythropoiesis. Biofactors. 1992;3:211-6.
12. Sawada K, Krantz SB, Dessypris EN, Koury ST, Sawyer ST. Human colony-forming units-erythroid do not require accessory cells, but do require direct interaction with insulin-like growth factor I and/or insulin for erythroid development. J Clin Invest. 1989;83:1701-9. doi: 10.1172/JCI114070.
13. Dijkhuizen MA, Wieringa FT, West CE, Muherdiyantiningsih, Muhilal. Concurrent micronutrient deficiencies in lactating mothers and their infants in Indonesia. Am J Clin Nutr. 2001;73:786-91.
14. Maskarinec G, Takata Y, Kaaks R. The relation between nutritional factors and insulin-like growth factor-I in premenopausal women of different ethnicity. Eur J Nutr. 2005;44:105. doi: 10.1007/s00394-004-0500-4.
15. Suzuki K, Ito Y, Hashimoto S, Kawado M, Inoue T, Ando M et al. Association of serum retinol and carotenoids with insulin-like growth factors and insulin-like growth factor binding protein-3 among control subjects of a nested casecontrol study in the Japan Collaborative Cohort Study. Asian Pac J Cancer Prev. 2009;10 Suppl:29-35.
16. Chellakooty M, Vangsgaard K, Larsen T, Scheike T, Falck-Larsen J, Legarth J, Andersson AM, Main KM, Skakkebaek, Juul A. A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth. J Clin Endocrinol Metab. 2004;89:384-91. doi: 10.1210/jc.2003-030282.
17. Unterman TG, Vazquez RM, Slas AJ, Martyn PA, Phillips LS. Nutrition and somatomedin. XIII. Usefulness of somatomedin-C in nutritional assessment. Am J Med. 1985; 78:228-34. doi: 10.1016/0002-9343(85)90431-0.
18. Thissen JP, Ketelslegers JM, Underwood LE. Nutritional regulation of the insulin-like growth factors. Endocr Rev. 1994;15:80-101. doi: 10.1210/er.15.1.80.
19. Morita S, Fernandez-Mejia C, Melmed S. Retinoic acid selectively stimulates growth hormone secretion and messenger ribonucleic acid levels in rat pituitary cells. Endocrinology. 1989;124:2052-6. doi: 10.1210/endo-124-5-2052.
20. Morita S, Matsuo K, Tsuruta M, Leng S, Yamashita S, Izumi M, Nagataki S. Stimulatory effect of retinoic acid on GH gene expression: the interaction of retinoic acid and triiodothyronine in rat pituitary cells. J Endocrinol. 1990;125:251-6. doi: 10.1677/joe.0.1250251.
21. Garcia-Villalba P, Au-Fliegner M, Samuels HH, Aranda A. Interaction of thyroid hormone and retinoic acid receptors on the regulation of the rat growth hormone gene promoter. Biochem Biophys Res Commun. 1993;191:580-6. doi: 10.1006/bbrc.1993.1257.
22. Dreyfuss ML, Stoltzfus RJ, Shrestha JB, Pradhan EK, LeClerq SC, Khatry SK, Shrestha SR, Katz J, Albonico M, West KP Jr. Hookworms, malaria and vitamin A deficiency contribute to anemia and iron deficiency among pregnant women in the plains of Nepal. J Nutr. 2000;130:2527-36.
23. Yamini S, West KP Jr, Wu L, Dreyfuss ML, Yang DX, Khatry SK. Circulating levels of retinol, tocopherol and carotenoid in Nepali pregnant and postpartum women following long-term beta-carotene and vitamin A supplementation. Eur J Clin Nutr. 2001;55:252-9. doi: 10.1038/sj.ejcn.1601152.
24. James WP, Mascie-Taylor GC, Norgan NG, Bistrian BR, Shetty PS, Ferro-Luzzi A. The value of arm circumference measurements in assessing chronic energy deficiency in Third World adults. Eur J Clin Nutr. 1994;48:883-94.
25. Path Analysis. Institute for Digital Research And Education. UCLA. [cited 2012/3/10]; Available from: http://www.ats.ucla.edu/stat/stata/faq/pathreg.htm.
26. Wright S. The Method of Path Coefficients. The Annals of Mathematical Statistics. 1934;5:161-215. doi: 10.1214/aoms/1177732676.
27. Boguszewski MC, Kamoi TO, Bento Radominski R, Boguszewski CL, Rosberg S, Rosario Filho NA, Sandrini Neto, Albertsson-Wikland K. Insulin-like growth factor-1, leptin, body composition, and clinical status interactions in children with cystic fibrosis. Horm Res. 2007;67:250-6. doi: 10.1159/000098480.
28. Arslan AA, Zeleniuch-Jacquotte A, Lukanova A, Afanasyeva Y, Katz J, Levitz M, Del Priore G, Toniolo P. Effects of parity on pregnancy hormonal profiles across ethnic groups with a diverse incidence of breast cancer. Cancer Epidemiol Biomarkers Prev. 2006;15:2123-30. doi: 10.1158/1055-9965.EPI-06-0470.
29. Elmlinger MW, Kuhnel W, Weber MM, Ranke MB. Reference ranges for two automated chemiluminescent assays for serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3). Clin Chem Lab Med. 2004;42:654-64. doi: 10.1515/CCLM.2004.112.
30. Holmes MD, Pollak MN, Hankinson SE. Lifestyle correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations. Cancer Epidemiol Biomarkers Prev. 2002;11:862-7.
31. Bedo G, Santisteban P, Aranda A. Retinoic acid regulates growth hormone gene expression. Nature. 1989;339:231-4. doi: 10.1038/339231a0.
32. Fu Z, Yoneyama M, Noguchi T, Kato H. Response of the insulin-like growth factor system to vitamin A depletion and repletion in rats. J Nutr Sci Vitaminol (Tokyo). 2002;48:453-60. doi: 10.3177/jnsv.48.453.
33. Fu Z, Noguchi T, Kato H. Vitamin A deficiency reduces insulin-like growth factor (IGF)-I gene expression and increases IGF-I receptor and insulin receptor gene expression in tissues of Japanese quail (Coturnix coturnix japonica). J Nutr. 2001;131:1189-94.
34. Han VK, Bassett N, Walton J, Challis JR. The expression of insulin-like growth factor (IGF) and IGF-binding protein (IGFBP) genes in the human placenta and membranes: evidence for IGF-IGFBP interactions at the feto-maternal interface. J Clin Endocrinol Metab. 1996;81:2680-93. doi: 10.1210/jcem.81.7.8675597.
35. Clagett-Dame M, DeLuca HF. The role of vitamin A in mammalian reproduction and embryonic development. Annu Rev Nutr. 2002;22:347-81.
36. Marceau G, Gallot D, Borel V, Lemery D, Dastugue B, Dechelotte P, Sapin V. Molecular and metabolic retinoid pathways in human amniotic membranes. Biochem Biophys Res Commun. 2006;346:1207-16. doi: 10.1016/j.bbrc.2006.06.024.
37. Sferruzzi-Perri AN, Owens JA, Standen P, Taylor RL, Robinson JS, Roberts CT. Early pregnancy maternal endocrine insulin-like growth factor I programs the placenta for increased functional capacity throughout gestation. Endocrinology. 2007;148:4362-70. doi: 10.1210/en.2007-0411.
38. Katz J, West KP Jr, Khatry SK, Pradhan EK, LeClerq SC, Christian P, Wu LS, Adhikari RK, Shrestha SR, Sommer A. Maternal low-dose vitamin A or beta-carotene supplementation has no effect on fetal loss and early infant mortality: a randomized cluster trial in Nepal. Am J Clin Nutr. 2000;71:1570-6.
39. Choi JW, Kim SK. Association of serum insulin-like growth factor-I and erythropoiesis in relation to body iron status. Ann Clin Lab Sci. 2004;34:324-8.
40. Nilsson-Ehle H, Bengtsson BA, Lindstedt G, Mellstrom D. Insulin-like growth factor-1 is a predictor of blood haemoglobin concentration in 70-yr-old subjects. Eur J Haematol. 2005;74:111-6. doi: 10.1111/j.16000609.2004.00374.x.
41. Sivan B, Lilos P, Laron Z. Effects of insulin-like growth factor-I deficiency and replacement therapy on the hematopoietic system in patients with Laron syndrome (primary growth hormone insensitivity). J Pediatr Endocrinol Metab. 2003;16:509-20. doi: 10.1515/JPEM.2003.16.4.509.
42. Sheashaa HA, Khalil A, Aarman MM, El-Shahat FB, Selim A, El-Gawad SS. Correction of hemodialysis anemia is associated with significant increase in serum concentration of IGF-I in patients treated with erythropoietin: a randomized controlled study. Int Urol Nephrol. 2005;37:153-8. doi: 10.1007/s11255-004-2360-5.
43. Succurro E, Arturi F, Caruso V, Rudi S, Sciacqua A, Andreozzi F, Hribal ML, Perticone R, Sesti G. Low insulinlike growth factor-1 levels are associated with anaemia in adult non-diabetic subjects. Thromb Haemost. 2011;105:365-70. doi: 10.1160/TH10-06-0379.
44. Masuda S, Chikuma M, Sasaki R. Insulin-like growth factors and insulin stimulate erythropoietin production in primary cultured astrocytes. Brain Res. 1997;746:63-70. doi: 10.1016/S0006-8993(96)01186-9.
45. Cusick SE, Tielsch JM, Ramsan M, Jape JK, Sazawal S, Black RE, Stoltzfus RJ. Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool children. Am J Clin Nutr. 2005;82:406-12.