Testing the Effect of Rare Compound-Heterozygous and Recessive Mutations in Case-Parent Sequencing Studies

Genetic Epidemiology

Volumn 39, Issue 3, 2015, Pages 166-172

  Jiang, Yu ^a   Mccarthy, Janice M ^a   Allen, Andrew S ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Compound heterozygous; Rare variant analyses; Transmission disequilibrium test

Indexed keywords

ARTICLE; COMPOUND HETEROZYGOUS MUTATION; CONTROLLED STUDY; DISEASE SIMULATION; FAMILY; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC ALGORITHM; GENOTYPE; HETEROZYGOTE; HUMAN; NULL HYPOTHESIS; PARENT; POPULATION; PROGENY; RECESSIVE GENE; RECESSIVE MUTATION; SAMPLE SIZE; BIOLOGICAL MODEL; COMPUTER SIMULATION; DNA SEQUENCE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; MUTATION; PROCEDURES; QUANTITATIVE TRAIT;

COMPUTER SIMULATION; GENES, RECESSIVE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HETEROZYGOTE; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MUTATION; PARENTS; QUANTITATIVE TRAIT, HERITABLE; SEQUENCE ANALYSIS, DNA;

EID: 84925101699     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21885     Document Type: Article

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