Inhibition of sphingosine kinase prevents lipopolysaccharide-induced preterm birth and suppresses proinflammatory responses in a murine model

American Journal of Pathology

Volumn 185, Issue 3, 2015, Pages 862-869

  Vyas, Vibhuti ^a   Ashby, Charles R ^a   Olgun, Nicole S ^a,b   Sundaram, Sruthi ^a   Salami, Oluwabukola ^a   Munnangi, Swapna ^c   Pekson, Ryan ^a   Mahajan, Prathamesh ^a   Reznik, Sandra E ^a,d  

^a ST JOHN'S UNIVERSITY   (United States)

^b WINTHROP UNIVERSITY HOSPITAL   (United States)

^c NASSAU UNIVERSITY MEDICAL CENTER   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN CONVERTING ENZYME; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PHOSPHOTRANSFERASE INHIBITOR; SPHINGOSINE KINASE; SPHINGOSINE KINASE INHIBITOR II; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; CYTOKINE; ENZYME INHIBITOR; PHOSPHOTRANSFERASE;

ABORTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; INFLAMMATION; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PREMATURE LABOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; METABOLISM; PLACENTA; PREGNANCY; PREMATURE BIRTH;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMALE; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLACENTA; PREGNANCY; PREMATURE BIRTH;

EID: 84925064801     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.10.026     Document Type: Article

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