Endemic and epidemic Acinetobacter baumannii clones: A twelve-year study in a tertiary care hospital Clinical microbiology and vaccines

BMC Microbiology

Volumn 15, Issue 1, 2015, Pages

  Villalón, Pilar ^a   Valdezate, Sylvia ^a   Cabezas, Teresa ^b   Ortega, Montserrat ^a   Garrido, Noelia ^a   Vindel, Ana ^c   Medina Pascual, María J ^a   Saez Nieto, Juan A ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL DE PONIENTE   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

A. baumannii; Clone; MLVA; PFGE; Sequence type

Indexed keywords

IMIPENEM; BACTERIAL DNA;

ACINETOBACTER BAUMANNII; ALLELE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CLONE; ENDEMIC DISEASE; EPIDEMIC; GENE INSERTION SEQUENCE; GENETIC SIMILARITY; GENETIC VARIABILITY; GENOTYPE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PULSED FIELD GEL ELECTROPHORESIS; VARIABLE NUMBER OF TANDEM REPEAT; ACINETOBACTER INFECTIONS; CLASSIFICATION; CROSS INFECTION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR EPIDEMIOLOGY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TERTIARY CARE CENTER;

ACINETOBACTER BAUMANNII;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; CROSS INFECTION; DNA, BACTERIAL; GENOTYPE; HUMANS; MINISATELLITE REPEATS; MOLECULAR EPIDEMIOLOGY; MULTILOCUS SEQUENCE TYPING; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TERTIARY CARE CENTERS;

EID: 84924993686     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/s12866-015-0383-y     Document Type: Article

References (31)

1. Gayoso CM, Mateos J, Méndez JA, Fernández-Puente P, Rumbo C, Tomás M, et al. Molecular mechanisms involved in the response to desiccation stress and persistence in Acinetobacter baumannii. J Proteome Res. 2013, doi:10.1021/pr.400603f.
2. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: emerging of a successful pathogen. Clin Microbiol Rev. 2008;21:835-82.
3. Higgins PG, Dammhayn C, Hackel M, Seifert H. Global spread of carbapenem-resistant Acinetobacter baumannii. J Antimicrob Chemother. 2010;65:233-8.
4. Villegas MV, Hartstein AI. Acinetobacter outbreaks, 1977-2000. Infect Control Hosp Epidemiol. 2003;24:284-95.
5. Towner KJ. Acinetobacter: an old friend, but a new enemy. J Hosp Infect. 2009;73:355-63.
6. Seifert H, Dolzani L, Bressan R, van der Reijden T, van Strijen B, Stefanik D, et al. Standardization and interlaboratory reproducibility assessment of pulsed-field gel electrophoresis generated fingerprints of Acinetobacter baumannii. J Clin Microbiol. 2005;43:4328-55.
7. Hamouda A, Evans BA, Towner KJ, Amyes SG. Characterization of epidemiologically unrelated Acinetobacter baumannii isolates from four continents by use of multilocus sequence typing, pulsed-field gel electrophoresis, and sequence-based typing of bla (OXA-51-like) genes. J Clin Microbiol. 2010;48:2476-83.
8. Bartual S, Seifert H, Hippler C, Domínguez MA, Wisplinghoff H, Rodríguez-Valera F. Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J Clin Microbiol. 2005;43:4382-90.
9. Diancourt L, Passet V, Nemec A, Dijkshoorn L, Brisse S. The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool. PLoS One. 2010;5:e10034.
10. Pourcel C, Minandri F, Hauck Y, D'Arezzo S, Imperi F, Vergnaud G, et al. Identification of variable-number tandem-repeat (VNTR) sequences in Acinetobacter baumannii and interlaboratory validation of an optimized multiple-locus VNTR analysis typing scheme. J Clin Microbiol. 2011;49:539-48.
11. Hu Y, Li B, Jin D, Cui Z, Tao X, Zhang B, et al. Comparison of multiple-locus variable-number tandem-repeat analysis with pulsed-field gel electrophoresis typing of Acinetobacter baumannii in China. J Clin Microbiol. 2013;51:1263-8.
12. Hauck Y, Soler C, Jault P, Mérens A, Gérome P, Mac Nab C, et al. Diversity of Acinetobacter baumannii in four French military hospitals, as assessed by multiple locus variable number of tandem repeat analysis. PLoS One. 2012;7:e44597.
13. Villalón P, Valdezate S, Medina-Pascual MJ, Rubio V, Vindel A, Saez-Nieto JA. Clonal diversity of nosocomial epidemic Acinetobacter baumanni strains isolated in Spain. J Clin Microbiol. 2011;49:875-82.
14. Hunter PR, Gaston MA. Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. J Clin Microbiol. 1998;26:2465-6.
15. Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18:268-81.
16. Di Popolo A, Giannouli M, Triassi M, Brisse S, Zarrilli R. Molecular epidemiology of multidrug-resistant Acinetobacter baumannii strains in four Mediterranean countries using a multilocus sequencing typing scheme. Clin Microbiol Infect. 2011;17:197-201.
17. Martins N, Dalla-Costa L, Uehara AA, Riley LW, Moreira BM. Emergence of Acinetobacter baumannii international clone II in Brazil: reflection of a global expansión. Infect Genet Evol. 2013;20:378-80.
18. Hojabri Z, Pajand O, Bonura C, Aleo A, Giammanco A, Mammina C. Molecular epidemiology of Acinetobacter baumannii in Iran: endemic and epidemic spread of multiresistant isolates. J Antimicrob Chemother. 2014. doi:10.1093.
19. Van Dessel H, Dijkshoorn L, van der Reijden T, Bakker N, Paauw A, van den Broek P, et al. Identification of a new geographically widespread multiresistant Acinetobacter baumannii clone from European hospitals. Res Microbiol. 2004;155:105-12.
20. Maiden MCJ. Multilocus sequence typing of bacteria. Annu Rev Microbiol. 2006;60:561-88.
21. Vergnaud G, Pourcel C. Multiple locus variable number of tandem repeats analysis. Methods Mol Biol. 2009;551:141-58.
22. Playford EG, Craig JC, Iredell JR. Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: risk factors for acquisition, infection and their consequences. J Hosp Infect. 2007;65:204-11.
23. Villalón P, Valdezate S, Medina-Pascual MJ, Carrasco G, Vindel A, Saez-Nieto JA. Epidemiology of the Acinetobacter-derived cephalosporinase, carbapenem-hydrolysing oxacillinase and metallo-β-lactamase genes, and of common insertion sequences, in epidemic clones of Acinetobacter baumannii from Spain. J Antimicrob Chemother. 2013;68:550-3.
24. Mosqueda N, Espinal P, Cosgaya C, Viota S, Plasensia V, Álvarez-Lerma F, et al. Globally expanding carbapenemase finally appears in Spain: nosocomial outbreak of Acinetobacter baumannii producing plasmid-encoded OXA-23 in Barcelona. Spain Antimicrob Agents Chemother. 2013;57:5155-7.
25. Koeleman JGM, van der Bijl MW, Stoof J, Vandenbroucke-Grauls CMJ, Savelkoul PHM. Antibiotic resistance is a major risk factor for epidemic behavior of Acinetobacter baumannii. Infect Control Hosp Epidemiol. 2001;22:284-8.
26. OXA-51-like genes for rapid assignment of acinetobacter baumannii clinical isolates to international clonal lineages. J Clin Microbiol. 2014;52:1653-7.
27. Grundmann H, Hori S, Tanner G. Determining confidence intervals when measuring genetic diversity and the discriminatory abilities of typing methods for microorganisms. J Clin Microbiol. 2001;39:4190-2.
28. Bou G, Martínez-Beltrán J. Cloning, nucleotide sequencing, and analysis of the gene encoding an AmpC β-lactamase in Acinetobacter baumannii. Antimicrob Agents Chemother. 2000;44:428-32.
29. Woodford N, Ellington MJ, Coehlo JM, Turton JF, Ward ME, Brown S, et al. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents. 2006;27:351-3.
30. Ellington MJ, Kistler J, Livermore DM, Woodford N. Multiplex PCR for rapid detection of genes encoding acquired metallo-β-lactamases. J Antimicrob Chemother. 2007;59:321-2.
31. Chen Y, Zhou Z, Jiang Y, Yu Y. Emergence of NDM-1-producing Acinetobacter baumannii in China. J Antimicrob Chemother. 2011;66:1255-9.