메뉴 건너뛰기




Volumn 35, Issue 3, 2015, Pages 1437-1446

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, with irinotecan hydrochloride on human colorectal and gastric cancer xenografts

Author keywords

5 FU resistance; Colorectal cancer; Gastric cancer; Irinotecan hydrochloride; TAS 102

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; IRINOTECAN; TAS 102; UNCLASSIFIED DRUG; CAMPTOTHECIN; DRUG COMBINATION; TRIFLURIDINE; URACIL;

EID: 84924973826     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (33)
  • 1
    • 84925015279 scopus 로고    scopus 로고
    • http://globocan.iarc.fr/Default.aspx.
  • 7
    • 1442329642 scopus 로고    scopus 로고
    • An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA
    • Emura T, Nakagawa F, Fujioka A, Ohshimo H, Yokogawa T, Okabe H and Kitazato K: An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA. Int J Mol Med 13: 249-255, 2004.
    • (2004) Int J Mol Med , vol.13 , pp. 249-255
    • Emura, T.1    Nakagawa, F.2    Fujioka, A.3    Ohshimo, H.4    Yokogawa, T.5    Okabe, H.6    Kitazato, K.7
  • 10
    • 0034657004 scopus 로고    scopus 로고
    • Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides
    • Fukushima M, Suzuki N, Emura T, Yano S, Kazuno H, Tada Y, Yamada Y and Asao T: Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides. Biochem Pharmacol 59: 1227-1236, 2000.
    • (2000) Biochem Pharmacol , vol.59 , pp. 1227-1236
    • Fukushima, M.1    Suzuki, N.2    Emura, T.3    Yano, S.4    Kazuno, H.5    Tada, Y.6    Yamada, Y.7    Asao, T.8
  • 11
    • 33644669986 scopus 로고    scopus 로고
    • Potentiation of the antitumor activity of α, α, α-trifluorothymidine by the co-administration of an inhibitor of thymidine phosphorylase at a suitable molar ratio in vivo
    • Emura T, Suzuki N, Fujioka A, Ohshimo H and Fukushima M: Potentiation of the antitumor activity of α, α, α-trifluorothymidine by the co-administration of an inhibitor of thymidine phosphorylase at a suitable molar ratio in vivo. Int J Oncol 27: 449-455, 2005.
    • (2005) Int J Oncol , vol.27 , pp. 449-455
    • Emura, T.1    Suzuki, N.2    Fujioka, A.3    Ohshimo, H.4    Fukushima, M.5
  • 12
    • 16644397018 scopus 로고    scopus 로고
    • A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA
    • Emura T, Suzuki N, Yamaguchi M, Ohshimo H, Fukushima M. A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA. Int J Oncol 25: 571-578, 2004.
    • (2004) Int J Oncol , vol.25 , pp. 571-578
    • Emura, T.1    Suzuki, N.2    Yamaguchi, M.3    Ohshimo, H.4    Fukushima, M.5
  • 13
    • 2542450966 scopus 로고    scopus 로고
    • A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells
    • Emura T, Murakami Y, Nakagawa F, Fukushima M and Kitazato K: A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells. Int J Mol Med 13: 545-549, 2004.
    • (2004) Int J Mol Med , vol.13 , pp. 545-549
    • Emura, T.1    Murakami, Y.2    Nakagawa, F.3    Fukushima, M.4    Kitazato, K.5
  • 14
    • 0034243820 scopus 로고    scopus 로고
    • Different mechanisms of acquired resistance to fluorinated pyrimidines in human colorectal cancer cells
    • Murakami Y, Kazuno H, Emura T, Tsujimoto H, Suzuki N and Fukushima M: Different mechanisms of acquired resistance to fluorinated pyrimidines in human colorectal cancer cells. Int J Oncol 17: 277-283, 2000.
    • (2000) Int J Oncol , vol.17 , pp. 277-283
    • Murakami, Y.1    Kazuno, H.2    Emura, T.3    Tsujimoto, H.4    Suzuki, N.5    Fukushima, M.6
  • 15
    • 84885101279 scopus 로고    scopus 로고
    • New challenges and inspired answers for anticancer drug discovery and development
    • Utsugi T: New challenges and inspired answers for anticancer drug discovery and development. Jpn J Clin Oncol 43: 945-953, 2013.
    • (2013) Jpn J Clin Oncol , vol.43 , pp. 945-953
    • Utsugi, T.1
  • 21
    • 71249128928 scopus 로고    scopus 로고
    • Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: A randomised phase III study
    • Boku N, Yamamoto S, Fukuda H, Shirao K, Doi T, Sawaki A, Koizumi W, Saito H, Yamaguchi K, Takiuchi H, Nasu J, Ohtsu A; Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group: Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase III study. Lancet Oncol 10: 1063-1069, 2009.
    • (2009) Lancet Oncol , vol.10 , pp. 1063-1069
    • Boku, N.1    Yamamoto, S.2    Fukuda, H.3    Shirao, K.4    Doi, T.5    Sawaki, A.6    Koizumi, W.7    Saito, H.8    Yamaguchi, K.9    Takiuchi, H.10    Nasu, J.11    Ohtsu, A.12
  • 22
    • 0024272364 scopus 로고
    • Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice
    • Morikawa K, Walker SM, Nakajima M, Pathak S, Jessup JM and Fidler IJ: Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res 48: 6863-6871, 1988.
    • (1988) Cancer Res , vol.48 , pp. 6863-6871
    • Morikawa, K.1    Walker, S.M.2    Nakajima, M.3    Pathak, S.4    Jessup, J.M.5    Fidler, I.J.6
  • 23
    • 0034885982 scopus 로고    scopus 로고
    • Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo
    • Fukushima M, Fujioka A, Uchida J, Nakagawa F and Takechi T: Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo. Eur J Cancer 37: 1681-1687, 2001.
    • (2001) Eur J Cancer , vol.37 , pp. 1681-1687
    • Fukushima, M.1    Fujioka, A.2    Uchida, J.3    Nakagawa, F.4    Takechi, T.5
  • 25
    • 33645749886 scopus 로고    scopus 로고
    • In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR
    • Balin-Gauthier D, Delord JP, Rochaix P, Mallard V, Thomas F, Hennebelle I, Bugat R, Canal P and Allal C: In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR. Cancer Chemother Pharmacol 57: 709-718, 2006.
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 709-718
    • Balin-Gauthier, D.1    Delord, J.P.2    Rochaix, P.3    Mallard, V.4    Thomas, F.5    Hennebelle, I.6    Bugat, R.7    Canal, P.8    Allal, C.9
  • 26
    • 0032582081 scopus 로고    scopus 로고
    • Testing strategies in multi-dose experiments including active control
    • Bauer P, Röhmel J, Maurer W and Hothorn L: Testing strategies in multi-dose experiments including active control. Stat Med 17: 2133-2146, 1998.
    • (1998) Stat Med , vol.17 , pp. 2133-2146
    • Bauer, P.1    Röhmel, J.2    Maurer, W.3    Hothorn, L.4
  • 28
    • 0027358510 scopus 로고
    • Synergism and lack of cross-resistance between short-term and continuous exposure to fluorouracil in human colon adenocarcinoma cells
    • Sobrero AF, Aschele C, Guglielmi AP, Mori AM, Melioli GG, Rosso R, Bertino JR: Synergism and lack of cross-resistance between short-term and continuous exposure to fluorouracil in human colon adenocarcinoma cells. J Natl Cancer Inst 85: 1937-44, 1993.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1937-1944
    • Sobrero, A.F.1    Aschele, C.2    Guglielmi, A.P.3    Mori, A.M.4    Melioli, G.G.5    Rosso, R.6    Bertino, J.R.7
  • 30
    • 0035418619 scopus 로고    scopus 로고
    • The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells
    • Jacob S, Aguado M, Fallik D and Praz F: The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells. Cancer Res 61: 6555-6562, 2001.
    • (2001) Cancer Res , vol.61 , pp. 6555-6562
    • Jacob, S.1    Aguado, M.2    Fallik, D.3    Praz, F.4
  • 31
    • 84867390244 scopus 로고    scopus 로고
    • Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase i inhibitors
    • Tomicic MT and Kaina B: Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase I inhibitors. Biochim Biophys Acta 1835: 11-27, 2013.
    • (2013) Biochim Biophys Acta , vol.1835 , pp. 11-27
    • Tomicic, M.T.1    Kaina, B.2
  • 32
    • 0025335797 scopus 로고
    • Anticachectic activity of 5'-deoxy-5-fluorouridine in a murine tumor cachexia model, colon 26 adenocarcinoma
    • Tanaka Y, Eda H, Fujimoto K, Tanaka T, Ishikawa T and Ishitsuka H: Anticachectic activity of 5'-deoxy-5-fluorouridine in a murine tumor cachexia model, colon 26 adenocarcinoma. Cancer Res 50: 4528-4532, 1990.
    • (1990) Cancer Res , vol.50 , pp. 4528-4532
    • Tanaka, Y.1    Eda, H.2    Fujimoto, K.3    Tanaka, T.4    Ishikawa, T.5    Ishitsuka, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.