Advanced glycation end products upregulate the endoplasmic reticulum stress in human periodontal ligament cells

Journal of Periodontology

Volumn 86, Issue 3, 2015, Pages 440-447

  Xu, Jie ^a   Xiong, Ming ^a   Huang, Bin ^a   Chen, Huangqin ^a  

^a HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Advanced; Diabetes mellitus; Endoplasmic reticulum stress; Glycation end products; Inflammation; Nuclear factorkappa B; Periodontal diseases

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ADVANCED GLYCATION END PRODUCT; ATF6 PROTEIN, HUMAN; AUTACOID; CASP12 PROTEIN, HUMAN; CASPASE 12; CCAAT ENHANCER BINDING PROTEIN; CHEMOKINE; DDIT3 PROTEIN, HUMAN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; INTERLEUKIN 6; INTERLEUKIN 8; MOLECULAR CHAPERONE GRP78; PERK KINASE; PROTEIN KINASE R;

ADOLESCENT; ADULT; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMAN; MALE; PERIODONTAL LIGAMENT; PROTEIN TRANSPORT; YOUNG ADULT;

ACTIVATING TRANSCRIPTION FACTOR 6; ADOLESCENT; ADULT; CASPASE 12; CCAAT-ENHANCER-BINDING PROTEINS; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; FEMALE; GLYCOSYLATION END PRODUCTS, ADVANCED; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; INTERLEUKIN-8; MALE; NF-KAPPA B; PERIODONTAL LIGAMENT; PROTEIN TRANSPORT; TRANSCRIPTION FACTOR CHOP; YOUNG ADULT;

EID: 84924968963     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2014.140446     Document Type: Article

References (28)

1. Cianciola LJ, Park BH, Bruck E, Mosovich L, Genco RJ. Prevalence of periodontal disease in insulin-dependent diabetes mellitus (juvenile diabetes). J Am Dent Assoc 1982;104:653-660.
2. Cutler CW, Machen RL, Jotwani R, Iacopino AM. Heightened gingival inflammation and attachment loss in type 2 diabetics with hyperlipidemia. J Periodontol 1999;70:1313-1321.
3. Bascones-Martínez A, González-Febles J, Sanz-Esporrín J. Diabetes and periodontal disease. Review of the literature. Am J Dent 2014;27:63-67.
4. Negrato CA, Tarzia O, Jovanovic L, Chinellato LE. Periodontal disease and diabetes mellitus. J Appl Oral Sci 2013;21:1-12.
5. Vlassara H, Uribarri J, Cai W, Striker G. Advanced glycation end product homeostasis: Exogenous oxidants and innate defenses. Ann N Y Acad Sci 2008; 1126:46-52.
6. Singh VP, Bali A, Singh N, Jaggi AS. Advanced glycation end products and diabetic complications. Korean J Physiol Pharmacol 2014;18:1-14.
7. Chawla D, Bansal S, Banerjee BD, Madhu SV, Kalra OP, Tripathi AK. Role of advanced glycation end product (AGE)-induced receptor (RAGE) expression in diabetic vascular complications. Microvasc Res 2014;95: 1-6.
8. Pusterla T, Nèmeth J, Stein I, et al. Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammationassociated liver carcinogenesis in mice. Hepatology 2013;58:363-373.
9. Pietropaoli D, Monaco A, Del Pinto R, Cifone MG, Marzo G, Giannoni M. Advanced glycation end products: Possible link between metabolic syndrome and periodontal diseases. Int J Immunopathol Pharmacol 2012;25:9-17.
10. Katz J, Bhattacharyya I, Farkhondeh-Kish F, Perez FM, Caudle RM, Heft MW. Expression of the receptor of advanced glycation end products in gingival tissues of type 2 diabetes patients with chronic periodontal disease: A study utilizing immunohistochemistry and RT-PCR. J Clin Periodontol 2005;32:40-44.
11. Abbass MM, Korany NS, Salama AH, Dmytryk JJ, Safiejko-Mroczka B. The relationship between receptor for advanced glycation end products expression and the severity of periodontal disease in the gingiva of diabetic and non diabetic periodontitis patients. Arch Oral Biol 2012;57:1342-1354.
12. Pietropaoli D, Tatone C, D'Alessandro AM, Monaco A. Possible involvement of advanced glycation end products in periodontal diseases. Int J Immunopathol Pharmacol 2010;23:683-691.
13. Smith MH, Ploegh HL, Weissman JS. Road to ruin: Targeting proteins for degradation in the endoplasmic reticulum. Science 2011;334:1086-1090.
14. Stutzmann GE, Mattson MP. Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease. Pharmacol Rev 2011;63:700-727.
15. Domon H, Takahashi N, Honda T, et al. Up-regulation of the endoplasmic reticulum stress-response in periodontal disease. Clin Chim Acta 2009;401:134-140.
16. Verfaillie T, Garg AD, Agostinis P. Targeting ER stress induced apoptosis and inflammation in cancer. Cancer Lett 2013;332:249-264.
17. Toth A, Nickson P, Mandl A, Bannister ML, Toth K, Erhardt P. Endoplasmic reticulum stress as a novel therapeutic target in heart diseases. Cardiovasc Hematol Disord Drug Targets 2007;7:205-218.
18. Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S. Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach. Am J Respir Cell Mol Biol 2008;38:541-550.
19. Poppek D, Grune T. Proteasomal defense of oxidative protein modifications. Antioxid Redox Signal 2006;8: 173-184.
20. Lee S-I, Kang K-L, Shin S-I, Herr Y, Lee Y-M, Kim E-C. Endoplasmic reticulumstress modulates nicotine-induced extracellular matrix degradation in human periodontal ligament cells. J Periodontal Res 2012;47:299-308.
21. AdamopoulosC, Farmaki E, Spilioti E, Kiaris H, Piperi C, Papavassiliou AG. Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells. Clin ChemLabMed 2014;52:151-160.
22. Tanaka K, Yamaguchi T, Kaji H, Kanazawa I, Sugimoto T. Advanced glycation end products suppress osteoblastic differentiation of stromal cells by activating endoplasmic reticulum stress. Biochem Biophys Res Commun 2013;438:463-467.
23. Liu J, Huang K, Cai GY, et al. Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling. Cell Signal 2014;26:110-121.
24. Shi L, Yu X, Yang H, Wu X. Advanced glycation end products induce human corneal epithelial cells apoptosis through generation of reactive oxygen species and activation of JNK and p38 MAPK pathways. PLoS ONE 2013;8:e66781.
25. Mealey BL, Rose LF. Diabetes mellitus and inflammatory periodontal diseases. Curr Opin Endocrinol Diabetes Obes 2008;15:135-141.
26. Chang PC, Chien LY, Yeo JF, et al. Progression of periodontal destruction and the roles of advanced glycation end products in experimental diabetes. J Periodontol 2013;84:379-388.
27. Kosakowska-Cholody T, Lin J, Srideshikan SM, Scheffer L, Tarasova NI, Acharya JK. HKH40A downregulates GRP78/BiP expression in cancer cells. Cell Death Dis 2014;5:e1240.
28. Wu J, Kaufman RJ. From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 2006;13:374-384.