Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML

Oncotarget

Volumn 5, Issue 20, 2014, Pages 9930-9938

  Zaitseva, Lyubov ^a   Murray, Megan Y ^a   Shafat, Manar S ^a   Lawes, Matthew J ^c   MacEwan, David J ^b   Bowles, Kristian M ^a,c   Rushworth, Stuart A ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

AML; BTK; CXCR4; Ibrutinib; SDF1

Indexed keywords

BETA ACTIN; BRUTON TYROSINE KINASE; CHEMOKINE RECEPTOR CXCR4; G PROTEIN COUPLED RECEPTOR; IBRUTINIB; INTERLEUKIN 2; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; PLERIXAFOR; PROTEIN KINASE B; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR RUNX1; AGAMMAGLOBULINAEMIA TYROSINE KINASE; CXCL12 PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; BONE MARROW STROMA CELL; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALE; MULTIPLE MYELOMA; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; TUMOR MICROENVIRONMENT; VERY ELDERLY; ANTAGONISTS AND INHIBITORS; CELL MOTION; DRUG EFFECTS; GENE SILENCING; GENETICS; LEUKEMIA, MYELOID, ACUTE; METABOLISM; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADULT; AGED; AGED, 80 AND OVER; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINE CXCL12; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; PROTEIN-TYROSINE KINASES; PYRAZOLES; PYRIMIDINES;

EID: 84924963486     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2479     Document Type: Article

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