Microfluidic Multiculture Assay to Analyze Biomolecular Signaling in Angiogenesis

Analytical Chemistry

Volumn 87, Issue 6, 2015, Pages 3239-3246

  Theberge, Ashleigh B ^a,b,c   Yu, Jiaquan ^a,c   Young, Edmond W K ^a,c,d   Ricke, William A ^b,c   Bushman, Wade ^b,c   Beebe, David J ^a,b,c  

^a Wisconsin Electric Machines and Power Electronics Consortium   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CELL CULTURE; CELLS; CROSSTALK; CYTOLOGY; ENDOTHELIAL CELLS; ENZYME ACTIVITY; MICROFLUIDICS;

CELL CULTURE METHODS; ENZYME INHIBITORS; MACULAR DEGENERATION; MATRIX METALLOPROTEINASE-12; MICROENVIRONMENTS; MICROFLUIDIC ASSAYS; MICROFLUIDIC PLATFORMS; TRADITIONAL TECHNIQUES;

BLOOD VESSELS;

MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE INHIBITOR;

ANGIOGENESIS; CELL LINE; CYTOLOGY; DEVICES; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; EQUIPMENT DESIGN; FIBROBLAST; HUMAN; MACROPHAGE; METABOLISM; MICROFLUIDIC ANALYSIS; PROCEDURES; SIGNAL TRANSDUCTION; SOLUBILITY; TUMOR MICROENVIRONMENT;

CELL LINE; CELLULAR MICROENVIRONMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; EQUIPMENT DESIGN; FIBROBLASTS; HUMANS; MACROPHAGES; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE INHIBITORS; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEOVASCULARIZATION, PHYSIOLOGIC; SIGNAL TRANSDUCTION; SOLUBILITY;

EID: 84924942217     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac503700f     Document Type: Article

References (47)

1. Carmeliet, P. Nature 2005, 438, 932-936
2. Folkman, J. Nat. Med. 1995, 1, 27-31
3. Shih, S. J.; Dall'Era, M. A.; Westphal, J. R.; Yang, J.; Sweep, C. G.; Gandour-Edwards, R.; Evans, C. P. Prostate Cancer Prostatic Dis. 2003, 6, 131-137
4. Ng, E. W.; Adamis, A. P. Can. J. Ophthalmol. 2005, 40, 352-368
5. Goel, S.; Duda, D. G.; Xu, L.; Munn, L. L.; Boucher, Y.; Fukumura, D.; Jain, R. K. Physiol. Rev. 2011, 91, 1071-1121
6. Stroock, A. D.; Fischbach, C. Tissue Eng., Part A 2010, 16, 2143-2146
7. Young, E. W. J. Lab. Autom. 2013, 18, 427-436
8. Song, J. W.; Munn, L. L. Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 15342-15347
9. Nguyen, D. H.; Stapleton, S. C.; Yang, M. T.; Cha, S. S.; Choi, C. K.; Galie, P. A.; Chen, C. S. Proc. Natl. Acad. Sci. U.S.A. 2013, 110, 6712-6717
10. Bischel, L. L.; Young, E. W.; Mader, B. R.; Beebe, D. J. Biomaterials 2013, 34, 1471-1477
11. Zheng, Y.; Chen, J.; Craven, M.; Choi, N. W.; Totorica, S.; Diaz-Santana, A.; Kermani, P.; Hempstead, B.; Fischbach-Teschl, C.; Lopez, J. A.; Stroock, A. D. Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 9342-9347
12. Miller, J. S.; Stevens, K. R.; Yang, M. T.; Baker, B. M.; Nguyen, D. H.; Cohen, D. M.; Toro, E.; Chen, A. A.; Galie, P. A.; Yu, X.; Chaturvedi, R.; Bhatia, S. N.; Chen, C. S. Nat. Mater. 2012, 11, 768-774
13. Liu, Y.; Markov, D. A.; Wikswo, J. P.; McCawley, L. J. Biomed. Microdevices 2011, 13, 837-846
14. Sudo, R.; Chung, S.; Zervantonakis, I. K.; Vickerman, V.; Toshimitsu, Y.; Griffith, L. G.; Kamm, R. D. FASEB J. 2009, 23, 2155-2164
15. Young, E. W. Integr. Biol. 2013, 5, 1096-1109
16. Bishop, E. T.; Bell, G. T.; Bloor, S.; Broom, I. J.; Hendry, N. F.; Wheatley, D. N. Angiogenesis 1999, 3, 335-344
17. Domenech, M.; Yu, H.; Warrick, J.; Badders, N. M.; Meyvantsson, I.; Alexander, C. M.; Beebe, D. J. Integr. Biol. 2009, 1, 267-274
18. Domenech, M.; Bjerregaard, R.; Bushman, W.; Beebe, D. J. Integr. Biol. 2012, 4, 142-152
19. Spencer, K. H.; Kim, M. Y.; Hughes, C. C.; Hui, E. E. Integr. Biol. 2014, 6, 382-387
20. Lang, J. D.; Berry, S. M.; Powers, G. L.; Beebe, D. J.; Alarid, E. T. Integr. Biol. 2013, 5, 807-816
21. Carney, C. M.; Muszynski, J. L.; Strotman, L. N.; Lewis, S. R.; O'Connell, R. L.; Beebe, D. J.; Theberge, A. B.; Jorgensen, J. S. Biol. Reprod. 2014, 91, 85
22. Brouzes, E.; Medkova, M.; Savenelli, N.; Marran, D.; Twardowski, M.; Hutchison, J. B.; Rothberg, J. M.; Link, D. R.; Perrimon, N.; Samuels, M. L. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 14195-14200
23. Holmes, D.; Pettigrew, D.; Reccius, C. H.; Gwyer, J. D.; van Berkel, C.; Holloway, J.; Davies, D. E.; Morgan, H. Lab Chip 2009, 9, 2881-2889
24. Young, E. W.; Pak, C.; Kahl, B. S.; Yang, D. T.; Callander, N. S.; Miyamoto, S.; Beebe, D. J. Blood 2012, 119, e76-85
25. Cooley, L. S.; Handsley, M. M.; Zhou, Z.; Lafleur, M. A.; Pennington, C. J.; Thompson, E. W.; Poschl, E.; Edwards, D. R. J. Cell Sci. 2010, 123, 3808-3816
26. Sarkanen, J. R.; Mannerstrom, M.; Vuorenpaa, H.; Uotila, J.; Ylikomi, T.; Heinonen, T. Front. Pharmacol. 2010, 1, 147
27. Oh, H.; Takagi, H.; Takagi, C.; Suzuma, K.; Otani, A.; Ishida, K.; Matsumura, M.; Ogura, Y.; Honda, Y. Invest. Ophthalmol. Visual Sci. 1999, 40, 1891-1898
28. Lin, E. Y.; Li, J. F.; Gnatovskiy, L.; Deng, Y.; Zhu, L.; Grzesik, D. A.; Qian, H.; Xue, X. N.; Pollard, J. W. Cancer Res. 2006, 66, 11238-11246
29. Lamagna, C.; Aurrand-Lions, M.; Imhof, B. A. J. Leukocyte Biol. 2006, 80, 705-713
30. Margheri, F.; Serrati, S.; Lapucci, A.; Chilla, A.; Bazzichi, L.; Bombardieri, S.; Kahaleh, B.; Calorini, L.; Bianchini, F.; Fibbi, G.; Del Rosso, M. Arthritis Rheum. 2010, 62, 2488-2498
31. Li, J.; Wang, J. J.; Peng, Q.; Chen, C.; Humphrey, M. B.; Heinecke, J.; Zhang, S. X. PloS One 2012, 7 e52699
32. Kerkela, E.; Ala-Aho, R.; Jeskanen, L.; Rechardt, O.; Grenman, R.; Shapiro, S. D.; Kahari, V. M.; Saarialho-Kere, U. J. Invest. Dermatol. 2000, 114, 1113-1119
33. Serrati, S.; Cinelli, M.; Margheri, F.; Guiducci, S.; Del Rosso, A.; Pucci, M.; Fibbi, G.; Bazzichi, L.; Bombardieri, S.; Matucci-Cerinic, M.; Del Rosso, M. J. Pathol. 2006, 210, 240-248
34. Duffy, D. C.; McDonald, J. C.; Schueller, O. J.; Whitesides, G. M. Anal. Chem. 1998, 70, 4974-4984
35. Regehr, K. J.; Domenech, M.; Koepsel, J. T.; Carver, K. C.; Ellison-Zelski, S. J.; Murphy, W. L.; Schuler, L. A.; Alarid, E. T.; Beebe, D. J. Lab Chip 2009, 9, 2132-2139
36. Kim, J.; Chaudhury, M. K.; Owen, M. J. J. Colloid Interface Sci. 2000, 226, 231-236
37. Tjiu, J. W.; Chen, J. S.; Shun, C. T.; Lin, S. J.; Liao, Y. H.; Chu, C. Y.; Tsai, T. F.; Chiu, H. C.; Dai, Y. S.; Inoue, H.; Yang, P. C.; Kuo, M. L.; Jee, S. H. J. Invest. Dermatol. 2009, 129, 1016-1025
38. Echeverria, V.; Worzella, T.; Skoien, A.; Lamers, C.; Meyvantsson, I.; Goulter, A.; Bowen, W.; Hayes, S. A Heterogeneous Angiogenesis Assay using Primary Cell Co-culture in Microchannels; BellBrook Labs: Madison, WI, 2008; http://www.bellbrooklabs.com/PDFs/SBS2008iuvoAngiogenesis.pdf.
39. Walker, G.; Beebe, D. J. Lab Chip 2002, 2, 131-134
40. Meyvantsson, I.; Warrick, J. W.; Hayes, S.; Skoien, A.; Beebe, D. J. Lab Chip 2008, 8, 717-724
41. Bussolino, F.; Di Renzo, M. F.; Ziche, M.; Bocchietto, E.; Olivero, M.; Naldini, L.; Gaudino, G.; Tamagnone, L.; Coffer, A.; Comoglio, P. M. J. Cell Biol. 1992, 119, 629-641
42. Ongusaha, P. P.; Kwak, J. C.; Zwible, A. J.; Macip, S.; Higashiyama, S.; Taniguchi, N.; Fang, L.; Lee, S. W. Cancer Res. 2004, 64, 5283-5290
43. Witzenbichler, B.; Asahara, T.; Murohara, T.; Silver, M.; Spyridopoulos, I.; Magner, M.; Principe, N.; Kearney, M.; Hu, J. S.; Isner, J. M. Am. J. Pathol. 1998, 153, 381-394
44. ten Dijke, P.; Goumans, M. J.; Pardali, E. Angiogenesis 2008, 11, 79-89
45. Natori, T.; Sata, M.; Washida, M.; Hirata, Y.; Nagai, R.; Makuuchi, M. Biochem. Biophys. Res. Commun. 2002, 297, 1058-1061
46. Simonini, A.; Moscucci, M.; Muller, D. W.; Bates, E. R.; Pagani, F. D.; Burdick, M. D.; Strieter, R. M. Circulation 2000, 101, 1519-1526
47. Newby, A. C. Arterioscler., Thromb., Vasc. Biol. 2008, 28, 2108-2114