메뉴 건너뛰기




Volumn 7, Issue , 2014, Pages 349-356

Applications of pharmacogenetics in children with attention-deficit/hyperactivity disorder

Author keywords

ADHD; Alpha 2 agonists; COMT; Dopamine receptors; Dopamine transporter; Stimulant side effects

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CENTRAL STIMULANT AGENT; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; METHYLPHENIDATE; NICOTINE;

EID: 84924916231     PISSN: None     EISSN: 11787066     Source Type: Journal    
DOI: 10.2147/PGPM.S52844     Document Type: Review
Times cited : (11)

References (37)
  • 3
    • 38349020431 scopus 로고    scopus 로고
    • Catecholamine and second messenger influences on pre­frontal cortical networks of “representational knowledge”: A rational bridge between genetics and the symptoms of mental illness
    • Arnsten AF. Catecholamine and second messenger influences on pre­frontal cortical networks of “representational knowledge”: a rational bridge between genetics and the symptoms of mental illness. Cereb Cortex. 2007;17 Suppl 1:i6-i15.
    • (2007) Cereb Cortex , vol.17 , pp. i6-i15
    • Arnsten, A.F.1
  • 4
    • 21244434801 scopus 로고    scopus 로고
    • Association and linkage of α-2A adrenergic receptor gene polymorphisms with childhood ADHD
    • Park L, Nigg JT, Waldman ID, et al. Association and linkage of α-2A adrenergic receptor gene polymorphisms with childhood ADHD. Mol Psychiatry. 2005;10(6):572-580.
    • (2005) Mol Psychiatry , vol.10 , Issue.6 , pp. 572-580
    • Park, L.1    Nigg, J.T.2    Waldman, I.D.3
  • 5
    • 58849144237 scopus 로고    scopus 로고
    • Dopamine vs noradrenaline: Inverted-U effects and ADHD theories
    • Levy F. Dopamine vs noradrenaline: inverted-U effects and ADHD theories. Aust N Z J Psychiatry. 2009;43(2):101-108.
    • (2009) Aust N Z J Psychiatry , vol.43 , Issue.2 , pp. 101-108
    • Levy, F.1
  • 6
    • 84880562760 scopus 로고    scopus 로고
    • Stimulant side effects and inverted-U: Implications for ADHD guidelines
    • Levy F. Stimulant side effects and inverted-U: implications for ADHD guidelines. Aust N Z J Psychiatry. 2013a;47(3):217-221.
    • (2013) Aust N Z J Psychiatry , vol.47 , Issue.3 , pp. 217-221
    • Levy, F.1
  • 7
    • 27744605990 scopus 로고    scopus 로고
    • Methylphenidate improves prefrontal cortical cognitive function through α2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in Attention Deficit Hyperactivity Disorder
    • Arnsten AFT, Dudley AG. Methylphenidate improves prefrontal cortical cognitive function through α2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in Attention Deficit Hyperactivity Disorder. Behav Brain Funct. 2005;1(1):2.
    • (2005) Behav Brain Funct , vol.1 , Issue.1
    • Arnsten, A.1    Dudley, A.G.2
  • 8
    • 77956971527 scopus 로고    scopus 로고
    • Methylphenidate and atomoxetine enhance prefrontal function through α2-adrenergic and dopamine D1 receptors
    • Gamo NJ, Wang M, Arnsten AFT. Methylphenidate and atomoxetine enhance prefrontal function through α2-adrenergic and dopamine D1 receptors. J Am Acad Child Adolesc Psychiatry. 2010;49(10):1011-1023.
    • (2010) J am Acad Child Adolesc Psychiatry , vol.49 , Issue.10 , pp. 1011-1023
    • Gamo, N.J.1    Wang, M.2    Arnsten, A.3
  • 9
    • 84924858616 scopus 로고    scopus 로고
    • Role of prefrontal cortex dopamine and noradrenaline circuitry in addiction
    • Belin D, editors, Rijeka, Croatia: InTech
    • Carboni E, Cadeddu R, Carta AR. Role of prefrontal cortex dopamine and noradrenaline circuitry in addiction. In: Belin D, editors. Addictions: From Pathophysiology to Treatment. Rijeka, Croatia: InTech; 2012:129-168.
    • (2012) Addictions: From Pathophysiology to Treatment , pp. 129-168
    • Carboni, E.1    Cadeddu, R.2    Carta, A.R.3
  • 10
    • 33847191328 scopus 로고    scopus 로고
    • Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory
    • Vijayraghavan S, Wang M, Birnbaum SG, Williams GV, Arnsten AF. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat Neurosci. 2007;10(3):376-384.
    • (2007) Nat Neurosci , vol.10 , Issue.3 , pp. 376-384
    • Vijayraghavan, S.1    Wang, M.2    Birnbaum, S.G.3    Williams, G.V.4    Arnsten, A.F.5
  • 11
    • 8444233260 scopus 로고    scopus 로고
    • The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes
    • Bilder RM, Volavka J, Lachman HM, Grace AA. The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology. 2004;29(11):1943-1961.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.11 , pp. 1943-1961
    • Bilder, R.M.1    Volavka, J.2    Lachman, H.M.3    Grace, A.A.4
  • 12
    • 84906224237 scopus 로고    scopus 로고
    • Functional implications of dop­amine D1 vs D2 receptors: A ‘prepare and select’ model of the striatal direct vs indirect pathways
    • Keeler JF, Pretsell DO, Robbins TW. Functional implications of dop­amine D1 vs D2 receptors: A ‘prepare and select’ model of the striatal direct vs indirect pathways. Neuroscience. 2014;282C:156-175.
    • (2014) Neuroscience , vol.282C , pp. 156-175
    • Keeler, J.F.1    Pretsell, D.O.2    Robbins, T.W.3
  • 13
    • 34247480145 scopus 로고    scopus 로고
    • D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons
    • Surmeier DJ, Ding J, Day M, Wang Z, Shen W. D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons. Trends Neurosci. 2007;30(5):228-235.
    • (2007) Trends Neurosci , vol.30 , Issue.5 , pp. 228-235
    • Surmeier, D.J.1    Ding, J.2    Day, M.3    Wang, Z.4    Shen, W.5
  • 14
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends Neurosci. 1989;12(10):366-375.
    • (1989) Trends Neurosci , vol.12 , Issue.10 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 15
    • 9344251126 scopus 로고    scopus 로고
    • Mechanisms underlying differential D1 versus D2 dopamine receptor regula­tion of inhibition in prefrontal cortex
    • Trantham-Davidson H, Neely LC, Lavin A, Seamans JK. Mechanisms underlying differential D1 versus D2 dopamine receptor regula­tion of inhibition in prefrontal cortex. J Neurosci. 2004;24(47): 10652-10659.
    • (2004) J Neurosci , vol.24 , Issue.47 , pp. 10652-10659
    • Trantham-Davidson, H.1    Neely, L.C.2    Lavin, A.3    Seamans, J.K.4
  • 16
    • 77957158276 scopus 로고    scopus 로고
    • Functional analysis of intron 8 and 3′ UTR variable number of tandem repeats of SLC6A3: Differ­ential activity of intron 8 variants
    • Hill M, Anney RJ, Gill M, Hawi Z. Functional analysis of intron 8 and 3′ UTR variable number of tandem repeats of SLC6A3: differ­ential activity of intron 8 variants. Pharmacogenomics J. 2010;10(5):442-447.
    • (2010) Pharmacogenomics J , vol.10 , Issue.5 , pp. 442-447
    • Hill, M.1    Anney, R.J.2    Gill, M.3    Hawi, Z.4
  • 17
    • 0028987091 scopus 로고
    • Association of attention-deficit disorder and the dopamine transporter gene
    • Cook EH Jr, Stein MA, Krasowski MD, et al. Association of attention-deficit disorder and the dopamine transporter gene. Am J Hum Genet. 1995;56(4):993-998.
    • (1995) Am J Hum Genet , vol.56 , Issue.4 , pp. 993-998
    • Cook, E.H.1    Stein, M.A.2    Krasowski, M.D.3
  • 18
    • 0030844034 scopus 로고    scopus 로고
    • Confirmation of asso­ciation between attention deficit hyperactivity disorder and a dopamine transporter polymorphism
    • Gill M, Daly G, Heron S, Hawi Z, Fitzgerald M. Confirmation of asso­ciation between attention deficit hyperactivity disorder and a dopamine transporter polymorphism. Mol Psychiatry. 1997;2(4):311-313.
    • (1997) Mol Psychiatry , vol.2 , Issue.4 , pp. 311-313
    • Gill, M.1    Daly, G.2    Heron, S.3    Hawi, Z.4    Fitzgerald, M.5
  • 19
    • 0032217057 scopus 로고    scopus 로고
    • Association and linkage of the dopamine transporter gene and attention-deficit hyperactivity disorder in children: Heterogeneity owing to diagnostic subtype and severity
    • Waldman ID, Rowe DC, Abramowitz A, et al. Association and linkage of the dopamine transporter gene and attention-deficit hyperactivity disorder in children: heterogeneity owing to diagnostic subtype and severity. Am J Hum Genet. 1998;63(6):1767-1776.
    • (1998) Am J Hum Genet , vol.63 , Issue.6 , pp. 1767-1776
    • Waldman, I.D.1    Rowe, D.C.2    Abramowitz, A.3
  • 20
    • 24944521591 scopus 로고    scopus 로고
    • Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: Sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype
    • Bellgrove MA, Hawi Z, Kirley A, Gill M, Robertson IH. Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype. Neuropsychologia. 2005a;43(13):1847-1857.
    • (2005) Neuropsychologia , vol.43 , Issue.13 , pp. 1847-1857
    • Bellgrove, M.A.1    Hawi, Z.2    Kirley, A.3    Gill, M.4    Robertson, I.H.5
  • 21
    • 0043092558 scopus 로고    scopus 로고
    • Enhancing the sensitivity of a sustained attention task to frontal damage: Convergent clinical and functional imaging evidence
    • Manly T, Owen AM, McAvinue L, et al. Enhancing the sensitivity of a sustained attention task to frontal damage: convergent clinical and functional imaging evidence. Neurocase. 2003;9(4):340-349.
    • (2003) Neurocase , vol.9 , Issue.4 , pp. 340-349
    • Manly, T.1    Owen, A.M.2    McAvinue, L.3
  • 22
    • 27844473803 scopus 로고    scopus 로고
    • Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder
    • Bellgrove MA, Hawi Z, Kirley A, Fitzgerald M, Gill M, Robertson IH. Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder. Neuropsychopharmacology. 2005;30(12):2290-2297.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.12 , pp. 2290-2297
    • Bellgrove, M.A.1    Hawi, Z.2    Kirley, A.3    Fitzgerald, M.4    Gill, M.5    Robertson, I.H.6
  • 23
    • 70449706011 scopus 로고    scopus 로고
    • Dopamine transporters in stria­tum correlate with deactivation in the default mode network during visuospatial attention
    • Tomasi D, Volkow ND, Wang R, et al. Dopamine transporters in stria­tum correlate with deactivation in the default mode network during visuospatial attention. PLoS ONE. 2009;4(6):e6102.
    • (2009) Plos ONE , vol.4 , Issue.6
    • Tomasi, D.1    Volkow, N.D.2    Wang, R.3
  • 24
    • 84893646320 scopus 로고    scopus 로고
    • Meta-analysis of the association between dopamine transporter genotype and response to methylpheni­date treatment in ADHD
    • Kambeitz J, Romanos M, Ettinger U. Meta-analysis of the association between dopamine transporter genotype and response to methylpheni­date treatment in ADHD. Pharmacogenomics J. 2014;14(1):77-84.
    • (2014) Pharmacogenomics J , vol.14 , Issue.1 , pp. 77-84
    • Kambeitz, J.1    Romanos, M.2    Ettinger, U.3
  • 25
    • 79956126861 scopus 로고    scopus 로고
    • FMRI activation during response inhibition and error processing: The role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD
    • Braet W, Johnson KA, Tobin CT, et al. fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD. Neuropsychologia. 2011;49(7):1641-1650.
    • (2011) Neuropsychologia , vol.49 , Issue.7 , pp. 1641-1650
    • Braet, W.1    Johnson, K.A.2    Tobin, C.T.3
  • 26
    • 84867896071 scopus 로고    scopus 로고
    • Dopamine transporter geno­type predicts behavioural and neural measures of response inhibition
    • Cummins TD, Hawi Z, Hocking J, et al. Dopamine transporter geno­type predicts behavioural and neural measures of response inhibition. Mol Psychiatry. 2012;17(11):1086-1092.
    • (2012) Mol Psychiatry , vol.17 , Issue.11 , pp. 1086-1092
    • Cummins, T.D.1    Hawi, Z.2    Hocking, J.3
  • 27
    • 84877585551 scopus 로고    scopus 로고
    • Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder
    • Kim BN, Kim JW, Cummins TDR, et al. Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder. J Clin Psychopharmacol. 2013;33(3):356-362.
    • (2013) J Clin Psychopharmacol , vol.33 , Issue.3 , pp. 356-362
    • Kim, B.N.1    Kim, J.W.2    Cummins, T.3
  • 28
    • 33646073783 scopus 로고    scopus 로고
    • Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs
    • Han DD, Gu HH. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs. BMC Pharmacol. 2006;6(1):6.
    • (2006) BMC Pharmacol , vol.6 , Issue.1
    • Han, D.D.1    Gu, H.H.2
  • 29
    • 84882773367 scopus 로고    scopus 로고
    • Dopamine receptors and the pharmacogenetics of side-effects of stimulant treat­ment for attention-deficit/hyperactivity disorder
    • Levy F, Wimalaweera S, Moul C, Brennan J, Dadds MR. Dopamine receptors and the pharmacogenetics of side-effects of stimulant treat­ment for attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23(6):423-425.
    • (2013) J Child Adolesc Psychopharmacol , vol.23 , Issue.6 , pp. 423-425
    • Levy, F.1    Wimalaweera, S.2    Moul, C.3    Brennan, J.4    Dadds, M.R.5
  • 30
    • 84924855020 scopus 로고    scopus 로고
    • Dopamine transporter genotype and stimulant dose-response in youth with attention-deficit/hyperactivity disorder
    • Stein MA, Waldman I, Newcorn J, Bishop J, Kittles R, Cook EH Jr. Dopamine transporter genotype and stimulant dose-response in youth with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2014;24(5):238-244.
    • (2014) J Child Adolesc Psychopharmacol , vol.24 , Issue.5 , pp. 238-244
    • Stein, M.A.1    Waldman, I.2    Newcorn, J.3    Bishop, J.4    Kittles, R.5    Cook, E.H.6
  • 31
    • 84879507861 scopus 로고    scopus 로고
    • Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dop­amine transporter binding in ADHD and healthy control subjects
    • Spencer TJ, Biederman J, Faraone SV, et al. Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dop­amine transporter binding in ADHD and healthy control subjects. Biol Psychiatry. 2013;74(2):84-89.
    • (2013) Biol Psychiatry , vol.74 , Issue.2 , pp. 84-89
    • Spencer, T.J.1    Biederman, J.2    Faraone, S.V.3
  • 32
    • 84890713561 scopus 로고    scopus 로고
    • Isopropylphenidate: An ester homolog of methylphenidate with sustained and selective dopamin­ergic activity and reduced drug interaction liability
    • Markowitz JS, Zhu H-J, Patrick KS. Isopropylphenidate: an ester homolog of methylphenidate with sustained and selective dopamin­ergic activity and reduced drug interaction liability. J Child Adolesc Psychopharmacol. 2013;23(10):648-654.
    • (2013) J Child Adolesc Psychopharmacol , vol.23 , Issue.10 , pp. 648-654
    • Markowitz, J.S.1    Zhu, H.-J.2    Patrick, K.S.3
  • 33
    • 8744228882 scopus 로고    scopus 로고
    • Effects of acute nicotine administration on behavioral inhibition in adolescents with attention-deficit/hyperactivity disorder
    • Potter AS, Newhouse PA. Effects of acute nicotine administration on behavioral inhibition in adolescents with attention-deficit/hyperactivity disorder. Psychopharmacology (Berl). 2004;176(2):182-194.
    • (2004) Psychopharmacology (Berl) , vol.176 , Issue.2 , pp. 182-194
    • Potter, A.S.1    Newhouse, P.A.2
  • 34
    • 32844461888 scopus 로고    scopus 로고
    • Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization
    • Levin ED, McClernon FJ, Rezvani AH. Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization. Psychopharmacology (Berl). 2006;184(3-4): 523-539.
    • (2006) Psychopharmacology (Berl) , vol.184 , Issue.3-4 , pp. 523-539
    • Levin, E.D.1    McClernon, F.J.2    Rezvani, A.H.3
  • 35
    • 0036237780 scopus 로고    scopus 로고
    • Persistence of nicotinic agonist RJR 2403 induced working memory improvement in rats
    • Levin ED, Christopher NC. Persistence of nicotinic agonist RJR 2403 induced working memory improvement in rats. Drug Dev Res. 2002;55(2):97-103.
    • (2002) Drug Dev Res , vol.55 , Issue.2 , pp. 97-103
    • Levin, E.D.1    Christopher, N.C.2
  • 36
    • 0033237390 scopus 로고    scopus 로고
    • AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats
    • Levin ED, Bettegowda C, Blosser J, Gordon J. AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats. Behav Pharmacol. 1999;10(6-7):675-680.
    • (1999) Behav Pharmacol , vol.10 , Issue.6-7 , pp. 675-680
    • Levin, E.D.1    Bettegowda, C.2    Blosser, J.3    Gordon, J.4
  • 37
    • 0032726966 scopus 로고    scopus 로고
    • A pilot controlled clinical trial of ABT-418, a cholinergic agonist, in the treatment of adults with attention deficit hyperactivity disorder
    • Wilens TE, Biederman J, Spencer TJ, et al. A pilot controlled clinical trial of ABT-418, a cholinergic agonist, in the treatment of adults with attention deficit hyperactivity disorder. Am J Psychiatry. 1999;156(12): 1931-1937.
    • (1999) Am J Psychiatry , vol.156 , Issue.12 , pp. 1931-1937
    • Wilens, T.E.1    Biederman, J.2    Spencer, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.