UbiA (Rv3806c) encoding DPPR synthase involved in cell wall synthesis is associated with ethambutol resistance in Mycobacterium tuberculosis

Tuberculosis

Volumn 95, Issue 2, 2015, Pages 149-154

  He, Lei ^a,c   Wang, Xiaobo ^a   Cui, Peng ^a   Jin, Jialin ^a   Chen, Jiazhen ^a   Zhang, Wenhong ^a   Zhang, Ying ^a,b  

^a FUDAN UNIVERSITY   (China)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

DPA level; Ethambutol resistance; Mechanism of resistance; Mycobacterium tuberculosis; ubiA gene

Indexed keywords

DECAPRENYLPHOSPHATE 5 PHOSPHORIBOSYLTRANSFERASE SYNTHASE; ETHAMBUTOL; KANAMYCIN; MESSENGER RNA; PHOSPHORIBOSYLTRANSFERASE; RIFAMPICIN; STREPTOMYCIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DECAPRENYLPHOSPHORYL-5-PHOSPHORIBOSE SYNTHASE; PHOSPHOTRANSFERASE; TUBERCULOSTATIC AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL STRAIN; BACTERIUM ISOLATE; COLORIMETRY; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; GENE MUTATION; GENE OVEREXPRESSION; LIQUID CHROMATOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; BIOSYNTHESIS; CELL WALL; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MICROBIAL SENSITIVITY TEST; MUTATION; PHYSIOLOGY; PROCEDURES;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CELL WALL; DRUG RESISTANCE, BACTERIAL; ETHAMBUTOL; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); POINT MUTATION; RNA, MESSENGER;

EID: 84924907487     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2014.12.002     Document Type: Article

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