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Volumn 347, Issue 6227, 2015, Pages 1253-1256
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Controlled-release mitochondrial protonophore reverses diabetes and protonophore reverses diabetes and steatohepatitis in rats
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Author keywords
[No Author keywords available]
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Indexed keywords
2,4 DINITROPHENOL;
ACYLCARNITINE;
ADIPONECTIN;
ALANINE AMINOTRANSFERASE;
ALBUMIN;
AMINOTRANSFERASE;
ASPARTATE AMINOTRANSFERASE;
CASPASE;
CERAMIDE;
CONTROLLED RELEASE MITOCHONDRIAL PROTONOPHORE;
CREATININE;
FATTY ACID;
FIBROBLAST GROWTH FACTOR 21;
GLUCOSE;
HYDROXYPROLINE;
INSULIN;
MESSENGER RNA;
NITROGEN;
SMOOTH MUSCLE ACTIN;
TRIACYLGLYCEROL;
UNCLASSIFIED DRUG;
UREA;
VERY LOW DENSITY LIPOPROTEIN;
DELAYED RELEASE FORMULATION;
GLUCOSE BLOOD LEVEL;
PROTON IONOPHORE;
CONCENTRATION (COMPOSITION);
DIABETES;
METABOLISM;
MITOCHONDRION;
OBESITY;
ORAL HEALTH;
RODENT;
ALANINE AMINOTRANSFERASE BLOOD LEVEL;
ALBUMIN BLOOD LEVEL;
AMINOTRANSFERASE BLOOD LEVEL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
AREA UNDER THE CURVE;
ARTICLE;
ASPARTATE AMINOTRANSFERASE BLOOD LEVEL;
BODY TEMPERATURE;
CONTROLLED RELEASE FORMULATION;
CREATININE BLOOD LEVEL;
DIABETES MELLITUS;
DRUG BLOOD LEVEL;
DRUG EFFICACY;
DRUG SAFETY;
ENERGY EXPENDITURE;
ENERGY METABOLISM;
FAT CONTENT;
FATTY LIVER;
GLUCONEOGENESIS;
GLUCOSE BLOOD LEVEL;
GLUCOSE TOLERANCE;
GLUCOSE TOLERANCE TEST;
GLYCOGEN ANALYSIS;
GLYCOGEN LIVER LEVEL;
HYPERTRIGLYCERIDEMIA;
INSULIN BLOOD LEVEL;
INSULIN RESISTANCE;
INSULIN SENSITIVITY;
LIPID DIET;
LIQUID CHROMATOGRAPHY;
LIVER CIRRHOSIS;
LIVER FIBROSIS;
LOW DRUG DOSE;
NICK END LABELING;
NONALCOHOLIC FATTY LIVER;
NONHUMAN;
NUCLEAR MAGNETIC RESONANCE;
OXIDATIVE PHOSPHORYLATION UNCOUPLING;
PRIORITY JOURNAL;
RAT;
TANDEM MASS SPECTROMETRY;
TREATMENT DURATION;
TRIACYLGLYCEROL BLOOD LEVEL;
UREA NITROGEN BLOOD LEVEL;
ADMINISTRATION AND DOSAGE;
ANIMAL;
DELAYED RELEASE FORMULATION;
DIABETES MELLITUS, TYPE 2;
DRUG EFFECTS;
LIPID METABOLISM;
LIVER MITOCHONDRION;
MALE;
METABOLISM;
MOUSE;
NON-ALCOHOLIC FATTY LIVER DISEASE;
OXIDATION REDUCTION REACTION;
RANDOMIZATION;
SKELETAL MUSCLE;
TOXICITY;
ZUCKER RAT;
RATTUS;
2,4-DINITROPHENOL;
ANIMALS;
BLOOD GLUCOSE;
DELAYED-ACTION PREPARATIONS;
DIABETES MELLITUS, TYPE 2;
GLUCOSE TOLERANCE TEST;
INSULIN RESISTANCE;
LIPID METABOLISM;
LIVER CIRRHOSIS;
MALE;
MICE;
MITOCHONDRIA, LIVER;
MUSCLE, SKELETAL;
NON-ALCOHOLIC FATTY LIVER DISEASE;
OXIDATION-REDUCTION;
PROTON IONOPHORES;
RANDOM ALLOCATION;
RATS;
RATS, ZUCKER;
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EID: 84924778498
PISSN: 00368075
EISSN: 10959203
Source Type: Journal
DOI: 10.1126/science.aaa0672 Document Type: Article |
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Times cited : (234)
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References (7)
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