The Transient Dermal Exposure II: Post-Exposure Absorption and Evaporation of Volatile Compounds

Journal of Pharmaceutical Sciences

Volumn 104, Issue 4, 2015, Pages 1499-1507

  Frasch, H Frederick ^a   Bunge, Annette L ^b  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b Department of Metallurgical and Materials Engineering   (United States)

Author keywords

absorption potential; passive diffusion transport; percutaneous; skin; solvent evaporation; transdermal

Indexed keywords

4 NITROANILINE; ALCOHOL; BENZYLBUTYLPHTHALATE; DIPHENYLAMINE; PHTHALIC ACID DERIVATIVE; UNCLASSIFIED DRUG; VOLATILE AGENT; 4-NITROANILINE; ANILINE DERIVATIVE; PHTHALIC ACID BENZYL BUTYL ESTER;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DERMIS; DRUG ABSORPTION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EXPOSURE; ENVIRONMENTAL EXPOSURE; EVAPORATION; FINAL VOLUME THEOREM; FINITE ELEMENT ANALYSIS; HUMAN; OCCUPATIONAL EXPOSURE; PARTITION COEFFICIENT; RISK ASSESSMENT; SKIN ABSORPTION; SKIN PERMEABILITY; SKIN SURFACE; STEADY STATE; THEORETICAL MODEL; THEORETICAL STUDY; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; INTRADERMAL DRUG ADMINISTRATION; KINETICS; METABOLISM; SKIN; VOLATILIZATION;

ADMINISTRATION, CUTANEOUS; ANILINE COMPOUNDS; ANIMALS; DIPHENYLAMINE; ETHANOL; HUMANS; KINETICS; MODELS, BIOLOGICAL; PHTHALIC ACIDS; SKIN; SKIN ABSORPTION; VOLATILIZATION;

EID: 84924765817     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24334     Document Type: Article

References (42)

1. Kasting GB. 2001. Kinetics of finite dose absorption through skin 1. Vanillylnonanamide. J Pharm Sci 90(2):202-212.
2. Kasting GB, Miller MA. 2006. Kinetics of finite dose absorption through skin 2: Volatile compounds. J Pharm Sci 95(2):268-280.
3. Anissimov YG, Roberts MS. 2001. Diffusion modeling of percutaneous absorption kinetics: 2. Finite vehicle volume and solvent deposited solids. J Pharm Sci 90(4):504-520.
4. Anissimov YG. 2008. Mathematical models for different exposure conditions. In Dermal absorption and toxicity assessment; Roberts MS, Walters KA, Eds. New York: Informa Healthcare, pp. 271-286.
5. Frasch HF. 2012. Dermal absorption of finite doses of volatile compounds. J Pharm Sci 101(7):2616-2619.
6. nd International Conference on Occupational and Environmental Exposure of Skin to Chemicals. Stockholm, Sweden: Karolinska Institute Accessed June 2005, at: https://ia600500.us.archive.org/21/items/OEESC2/AbPost081Bunge.html, accessed 08/16/2014.
7. Frasch HF, Barbero AM. 2008. The transient dermal exposure: Theory and experimental examples using skin and silicone membranes. J Pharm Sci 97(4):1578-1592.
8. nd ed. Oxford: Oxford University Press, p. 50.
9. th ed. Boca Raton: CRC Press, Differential Equations Table III, p. 376.
10. Gajjar RM, Miller MA, Kasting GB. 2013. Evaporation of volatile organic compounds from human skin in vitro. Ann Occup Hyg 57(7):853-865.
11. WHO (World Health Organization). 2006. Environmental health criteria 235, dermal absorption. Geneva, Switzerland: WHO Press.
12. USEPA (United States Environmental Protection Agency). 1998. Health effects test guidelines, OPPTS 870.7600 dermal penetration, EPA 712-C-98-350, August. Washington, DC: USEPA.
13. OECD (Organization for Economic Co-operation and Development). 2004a. OECD guideline for the testing of chemical, skin absorption: In vitro method, 428, Adopted April 13. Paris, France: OECD.
14. OECD (Organization for Economic Co-operation and Development). 2004b. OECD guideline for the testing of chemical, skin absorption: In vivo method, No. 427, Adopted April 13. Paris, France: OECD.
15. OECD (Organization for Economic Co-operation and Development). 2004c. Guidance document for the conduct of skin absorption studies. OECD series on testing and assessment, No. 28, Adopted March 5. Paris, France: OECD.
16. ECETOC (European Centre for Ecotoxicology and Toxicology of Chemicals). 1993. Percutaneous absorption. Monograph No 20, ISSN-0773-6347-20. Brussels, Belgium: ECETOC.
17. EC (European Commission). 2004. Guidance document on dermal absorption, health & consumer protection directorate-general, Sanco/222/2000 rev. 7, March 19.
18. US EPA. 2004. In vitro dermal absorption rate testing of certain chemicals of interest to the Occupational Safety and Health Administration, Fed Reg, 69 (April 26, 2004): 22402-22441, DOCID:fr26ap04-21. Washington, DC: US EPA. Accessed August 29, 2014, at: http://www.epa.gov/fedrgstr/EPA-TOX/2004/April/Day-26/t9409.htm.
19. COLIPA (European Cosmetic Toiletry and Perfumery Association). 1995. Cosmetic ingredients: Guidelines for percutaneous absorption/penetration. Brussels, Belgium: COLIPA Publications.
20. th plenary of 28 March 2006, European Commission, Health &Consumer Protection Directorate-General, Directorate C-Public Health and Risk assessment, C7-Risk assessment, SCCP/0970/06.
21. Steiling W, Kreutz J, Hofer H. 2001. Percutaneous penetration/dermal absorption of hair dyes in vitro. Toxicol in Vitro 15:565-570.
22. th plenary meeting of October 20, 2003, SCCNFP/0690/03 Final.
23. Diembeck W, Beck H, Benech-Kieffer F, Courtellemont P, Dupuis J, Lovell W, Paye M, Spengler J, Steiling W. 1999. Test guidelines for in vitro assessment of dermal absorption and percutaneous penetration of cosmetic ingredients. Food Chem Toxicol 37:191-205.
24. EFSA (European Food Safety Authority). 2012. Guidance on dermal absorption, panel on plant protection products and their residues (PPR). EFSA J 10(4):2665, 30 pp.
25. NIOSH. 2009. Current intelligence bulletin 61: A strategy for assigning new NIOSH skin notations. DHHS (NIOSH) Publication No. 2009-147, Cincinnati, Ohio. Accessed July 28, 2009, at: http://www.cdc.gov/niosh/docs/2009-147/default.html.
26. Liu Z, Ye W, Little JC. 2013. Predicting emissions of volatile and semivolatile organic compounds from building materials: A review. Build Environ 64:7-25.
27. th Ed. Upper Saddle River, New Jersey: Prentice Hall.
28. Wolfram|Alpha. 2014. Wolfram Alpha LLC. Accessed August 20, 2014, at: http://www.wolframalpha.com/input/?i=air±viscosity±at±25C±and±1plusmn;atmosphere±divided±by±air±density±at±25C±and±1±atmosphere.
29. Cussler EL. 1984. Diffusion-mass transfer in fluid systems. Cambridge: Cambridge University Press, p. 112.
30. th Ed. New York: McGraw-Hill Inc.
31. Girman JR. 1993. Simple modeling to determine appropriate operating conditions for emission testing in small chambers, In Modeling of indoor air quality and exposure, ASTM STP 1205; Niren L. Nagda, Ed. Philadelphia: American Society for Testing and Materials, pp. 145-148.
32. Evans M. 1980. Housing, climate, and comfort. New York: J Wiley & Sons, Inc., p. 175.
33. Knudsen HN, Kjaer UD, Nielsen PA, Wolkoff P. 1999. Sensory and chemical characterization of VOC emissions from building products: Impact of concentration and air velocity. Atmos Environ 33:1217-1230.
34. VENT-AXIA. 2010. Ventilation handbook. Vent-Axia. Accessed August 15, 2014, at: http://www.scribd.com/doc/25144576/VENT-AXIA-Ventilation-Handbook.
35. Chemtura. 2006. Determination of the in vitro absorption rate of diphenylamine, ID No. EPA-HQ-OPPT-2003-0006-0330, Final report to US EPA for TSCA Section 4 (Docket identification number OPPT-2003-006). Accessed August 20, 2014, at: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2003-0006-0330).
36. Scheuplein RJ, Blank IH. 1973. Mechanism of percutaneous absorption. IV. Penetration of nonelectrolytes (alcohols) from aqueous solutions and from pure liquids. J Invest Dermatol 60:286-296.
37. 14C]-nitroaniline in vitro, ID No. EPA-HQ-OPPT-2003-0006-0320, Final report to US EPA for TSCA Section 4 (Docket identification number OPPT-2003-006). Accessed August 29, 2014, at: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2003-0006-0320).
38. Reddy MB, Bunge AL. 2005. Does desquamation reduce permeation? In Percutaneous absorption, drugs-cosmetics-mechanismsmethodology; Bronaugh RL, Maibach HI, Eds. Boca Raton, Florida; Taylor & Francis, pp. 1414-1419.
39. Reddy MB, Guy RH, Bunge AL. 2000. Does epidermal turnover reduce percutaneous penetration? Pharm Res 17:1414-1419.
40. USEPA. 2004. Risk assessment guidance for superfund, volume I: Human health evaluation manual (Part E, supplemental guidance for dermal risk assessment), Final, EPA/540/R/99/005, OSWER 9285.7-02EP, PB99-963312, July, 2004. Washington, DC: Office of Superfund Remediation and Technology Innovation. Accessed August 29, 2014, at: http://www.epa.gov/oswer/riskassessment/ragse/index.htm.
41. Anissimov YG, Roberts MS. 2009. Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics. J Pharm Sci 98(2): 772-781.
42. Frasch HF, Barbero AM, Hettic JM, Nitsche JM. 2011. Tissue binding affects the kinetics of theophylline diffusion through the stratum corneum barrier layer of skin. J Pharm Sci 100(7):2989-2995.