MicroRNA-204 targets signal transducer and activator of transcription 5 expression and inhibits proliferation of B-cell lymphoma cells

Molecular Medicine Reports

Volumn 11, Issue 6, 2015, Pages 4567-4572

  Wu, Li ^a   Li, Yong ^a   Fan, Jian Min ^b   Zhang, Zhi Min ^b   Ouyang, Jin Ling ^a   Ni, Ting Ting ^a   Wu, Hai Xia ^a   Li, Hang ^a  

^a GUIZHOU PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b GUIYANG UNIVERSITY   (China)

Author keywords

B cell lymphoma; MicroRNA 204; Proliferation; Signal transducer and activator of transcription 5

Indexed keywords

B RAF KINASE; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; NON RECEPTOR TYROSINE KINASE C STEROID RECEPTOR CO ACTIVATOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ANTISENSE OLIGONUCLEOTIDE; MICRORNA; MIRN204 MICRORNA, HUMAN; STAT5 PROTEIN;

ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVATION; GASTRIC CANCER CELL LINE; GENE SILENCING; HUMAN; HUMAN CELL; POSITIVE FEEDBACK; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH CANCER; 3' UNTRANSLATED REGION; ANTAGONISTS AND INHIBITORS; B CELL LYMPHOMA; CELL PROLIFERATION; CELL TRANSFORMATION; CHEMISTRY; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; SEQUENCE ALIGNMENT; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LYMPHOMA, B-CELL; MICRORNAS; OLIGONUCLEOTIDES, ANTISENSE; SEQUENCE ALIGNMENT; STAT5 TRANSCRIPTION FACTOR;

EID: 84924678346     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3298     Document Type: Article

References (19)

1. Seton-Rogers S: Lymphoma: Epigenetic therapy gains momentum. Nat Rev Cancer 12: 798, 2012.
2. Young RM and Staudt LM: Targeting pathological B cell receptor signalling in lymphoid malignancies. Nat Rev Drug Discov 12: 229-243, 2013.
3. Ameres SL and Zamore PD: Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol 14: 475-488, 2013.
4. Sun K and Lai EC: Adult-specific functions of animal microRNAs. Nat Rev Genet 14: 535-548, 2013.
5. Lawrie CH: MicroRNA expression in lymphoma. Expert Opin Biol Ther 7: 1363-1374, 2007.
6. Wang LQ, Liang R and Chim CS: Methylation of tumor suppressor microRNAs: lessons from lymphoid malignancies. Expert Rev Mol Diagn 12: 755-765, 2012.
7. Lawrie CH: MicroRNAs and lymphomagenesis: a functional review. Br J Haematol 160: 571-581, 2013.
8. Sandhu SK, Volinia S, Costinean S, et al: miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the E-miR-155 transgenic mouse model. Proc Natl Acad Sci USA 109: 20047-20052, 2012.
9. Ralfkiaer U, Hagedorn PH, Bangsgaard N, et al: Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL). Blood 118: 5891-5900, 2011.
10. Huang J, Zhao L, Xing L and Chen D: MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 28: 357-364, 2010.
11. Wang FE, Zhang C, Maminishkis A, et al: MicroRNA-204/211 alters epithelial physiology. FASEB J 24: 1552-1571, 2010.
12. Conte I, Carrella S, Avellino R, et al: miR-204 is required for lens and retinal development via Meis2 targeting. Proc Natl Acad Sci USA 107: 15491-15496, 2010.
13. Paulin R, Courboulin A, Barrier M and Bonnet S: From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension. J Mol Med (Berl) 89: 1089-1101, 2011.
14. Chung TK, Lau TS, Cheung TH, et al: Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1. Int J Cancer 130: 1036-1045, 2012.
15. Sacconi A, Biagioni F, Canu V, et al: miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer. Cell Death Dis 3: e423, 2012.
16. Ying Z, Li Y, Wu J, et al: Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype. Cancer Res 73: 990-999, 2013.
17. Malin S, McManus S and Busslinger M: STAT5 in B cell development and leukemia. Curr Opin Immunol 22: 168-176, 2010.
18. Blix ES, Irish JM, Husebekk A, et al: Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma. BMC Cancer 12: 478, 2012.
19. Kirk R: Haematological cancer: Hit the lymphoma, JAK. Nat Rev Clin Oncol 9: 608, 2012.