Immortal time bias in drug safety cohort studies: Spontaneous abortion following nonsteroidal antiinflammatory drug exposure

American Journal of Obstetrics and Gynecology

Volumn 212, Issue 3, 2015, Pages 307.e1-307.e6

  Daniel, Sharon ^a,b   Koren, Gideon ^b,c   Lunenfeld, Eitan ^a   Levy, Amalia ^a,b  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BeMORE Collaboration (Ben Gurion Motherisk Obstetric Registry of Exposure Collaboration)   (Israel)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

ibuprofen; immortal time bias; miscarriage; NSAIDs; spontaneous abortions

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; ETODOLAC; ETORICOXIB; IBUPROFEN; INDOMETACIN; LORNOXICAM; NABUMETONE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT;

ABORTION; ARTICLE; COHORT ANALYSIS; DRUG SAFETY; FOLLOW UP; HIGH RISK PREGNANCY; HUMAN; PREGNANCY; PREGNANCY OUTCOME; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RISK ASSESSMENT; SPONTANEOUS ABORTION; STATISTICAL ANALYSIS; TERATOGENICITY; ADOLESCENT; ADULT; CHEMICALLY INDUCED; DRUG SURVEILLANCE PROGRAM; EVALUATION STUDY; FEMALE; METHODOLOGY; MIDDLE AGED; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICAL BIAS; STATISTICAL MODEL; TIME; YOUNG ADULT;

ABORTION, SPONTANEOUS; ADOLESCENT; ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIAS (EPIDEMIOLOGY); DATA INTERPRETATION, STATISTICAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; MIDDLE AGED; MODELS, STATISTICAL; PREGNANCY; PROPORTIONAL HAZARDS MODELS; RESEARCH DESIGN; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; YOUNG ADULT;

EID: 84924678239     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2014.09.028     Document Type: Article

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