Fetal exposure to nonsteroidal anti-inflammatory drugs and spontaneous abortions

CMAJ. Canadian Medical Association Journal

Volumn 186, Issue 5, 2014, Pages

  Daniel, Sharon ^a   Koren, Gideon ^a,c   Lunenfeld, Eitan ^a   Bilenko, Natalya ^a,b   Ratzon, Ronit ^a   Levy, Amalia ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b MINISTRY OF HEALTH   (Israel)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT;

ADOLESCENT; ADULT; AGE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; HYPOTHYROIDISM; INFLAMMATORY DISEASE; ISRAEL; MAJOR CLINICAL STUDY; PREGNANT WOMAN; PRENATAL DRUG EXPOSURE; RISK ASSESSMENT; SMOKING; SPONTANEOUS ABORTION;

ABORTION, SPONTANEOUS; ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE 2 INHIBITORS; FEMALE; FETUS; HUMANS; INDOMETHACIN; MIDDLE AGED; PREGNANCY; PREGNANCY OUTCOME; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 84896509551     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: 10.1503/cmaj.130605     Document Type: Article

References (36)

1. Daniel S, Matok I, Gorodischer R, et al. Major malformations following exposure to nonsteroidal antiinflammatory drugs during the first trimester of pregnancy. J Rheumatol 2012;39:2163-9.
2. Werler MM, Mitchell AA, Hernandez-Diaz S, et al. Use of overthe-counter medications during pregnancy. Am J Obstet Gynecol 2005;193:771-7.
3. Grosser T, Smyth E, Fitz Gerald G. Anti-inflammatory, antipyretic, and analgesic agents; pharmacotherapy of gout. In: Brunton L, Chabner B, Knollmann B, editors. Goodman & Gilman's the pharmacological basis of therapeutics. 12th ed. New York (NY): McGraw-Hill; 2011.
4. Prernoll M, Benson R. Early pregnancy risks. In: Alan HD, Lauren N, editors. Current diagnosis & treatment, obstetrics & gynecology. 10th ed. New York (NY): McGraw-Hill; 2007.
5. Harlap S, Shiono PH. Alcohol, smoking, and incidence of spontaneous abortions in the first and second trimester. Lancet 1980;2:173-6.
6. Wang X, Chen C, Wang L, et al. Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study. Fertil Steril 2003;79:577-84.
7. Wilcox AJ, Weinberg CR, O'Connor JF, et al. Incidence of early loss of pregnancy. N Engl J Med 1988;319:189-94.
8. Nybo Andersen AM, Wohlfahrt J, Christens P, et al. Maternal age and fetal loss: population based register linkage study. BMJ 2000;320:1708-12.
9. Pritts EA, Parker WH, Olive DL. Fibroids and infertility: an updated systematic review of the evidence. Fertil Steril 2009;91:1215-23.
10. Klatsky PC, Tran ND, Caughey AB, et al. Fibroids and reproductive outcomes: a systematic literature review from conception to delivery. Am J Obstet Gynecol 2008;198:357-66.
11. Salim R, Regan L, Woelfer B, et al. A comparative study of the morphology of congenital uterine anomalies in women with and without a history of recurrent first trimester miscarriage. Hum Reprod 2003;18:162-6.
12. Mills JL, Simpson JL, Driscoll SG, et al. Incidence of spontaneous abortion among normal women and insulin-dependent diabetic women whose pregnancies were identified within 21 days of conception. N Engl J Med 1988;319:1617-23.
13. Abalovich M, Gutierrez S, Alcaraz G, et al. Overt and subclinical hypothyroidism complicating pregnancy. Thyroid 2002;12:63-8.
14. Clifford K, Rai R, Watson H, et al. Does suppressing luteinising hormone secretion reduce the miscarriage rate? Results of a randomised controlled trial. BMJ 1996;312:1508-11.
15. Robertson L, Wu O, Langhorne P, et al. Thrombophilia in pregnancy: a systematic review. Br J Haematol 2006;132:171-96.
16. Branch DW, Khamashta MA. Antiphospholipid syndrome: obstetric diagnosis, management, and controversies. Obstet Gynecol 2003;101:1333-44.
17. ESHRE Capri Workshop Group. Nutrition and reproduction in women. Hum Reprod Update 2006;12:193-207.
18. Mishra GD, Dobson AJ, Schofield MJ. Cigarette smoking, menstrual symptoms and miscarriage among young women. Aust N Z J Public Health 2000;24:413-20.
19. Henriksen TB, Hjollund NH, Jensen TK, et al. Alcohol consumption at the time of conception and spontaneous abortion. Am J Epidemiol 2004;160:661-7.
20. Weng X, Odouli R, Li DK. Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. Am J Obstet Gynecol 2008;198:279.e1-8.
21. Keim SA, Klebanoff MA. Aspirin use and miscarriage risk. Epidemiology 2006;17:435-9.
22. Nielsen GL, Skriver M V, Pedersen L, et al. Danish group reanalyses miscarriage in NSAID users. BMJ 2004;328:109.
23. Li DK, Liu L, Odouli R. Exposure to non-steroidal anti-inflammatory drugs during pregnancy and risk of miscarriage: population based cohort study. BMJ 2003;327:368.
24. Nakhai-Pour HR, Broy P, Sheehy O, et al. Use of nonaspirin nonsteroidal anti-inflammatory drugs during pregnancy and the risk of spontaneous abortion. CMAJ 2011;183:1713-20.
25. Finer LB, Zolna MR. Unintended pregnancy in the United States: incidence and disparities, 2006. Contraception 2011 2011;84:478-85.
26. Angel D. Patterns of fertility in 2006 [article in Hebrew]. Central Bureau of Statistics: Jerusalem (Israel); 2007. Available: www.cbs.gov. il/hodaot2007n/01-07-215b.pdf (accessed 2014 Jan. 15).
27. Rafaela C. National Insurance Institute of Israel, periodic survey [article in Hebrew]. National Insurance Institute of Israel: Jerusalem (Israel); 2012. Available: www.btl.gov. il/Publications/survey/Documents/seker-238.pdf (accessed 2013 Sept. 1).
28. Suissa S. Immortal time bias in pharmaco-epidemiology. Am J Epidemiol 2008;167:492-9.
29. Roman APM. Late pregnancy complications. In: Alan HD, Lauren N, editors. Current diagnosis & treatment, obstetrics & gynecology. 10th ed. New York (NY): McGraw-Hill; 2007.
30. Schiavetti B, Clavenna A, Campi R, et al. NSAIDs during pregnancy and risk of miscarriage: true risks or only suspicions? BMJ 2004;328:108, author reply 108-9.
31. Clark CA, Spitzer KA, Laskin CA, et al. Spontaneous abortion and NSAIDs. CMAJ 2011;183:2145, author reply 2145-6.
32. Bérard A, Lacasse A. Validity of perinatal pharmacoepidemiologic studies using data from the RAMQ administrative database. Can J Clin Pharmacol 2009;16:e360-9.
33. Lanas A, Polo-Tomas M, Roncales P, et al. Prescription of and adherence to non-steroidal anti-inflammatory drugs and gastroprotective agents in at-risk gastrointestinal patients. Am J Gastroenterol 2012;107:707-14.
34. Ray WA, Griffin MR. Use of Medicaid data for pharmacoepidemiology. Am J Epidemiol 1989;129:837-49.
35. West SL, Savitz DA, Koch G, et al. Recall accuracy for prescription medications: self-report compared with database information. Am J Epidemiol 1995;142:1103-12.
36. Johnson RE, Vollmer WM. Comparing sources of drug data about the elderly. J Am Geriatr Soc 1991;39:1079-84.