Hodgkin lymphoma is as common as non-Hodgkin lymphoma in HIV-positive patients with sustained viral suppression and limited immune deficiency: A prospective cohort study

HIV Medicine

Volumn 16, Issue 4, 2015, Pages 261-264

  Hoffmann, C ^a,b   Hentrich, M ^c   Gillor, D ^d   Behrens, G ^e,o   Jensen, B ^f   Stoehr, A ^g   Esser, S ^h   van Lunzen, J ⁱ   Krznaric, I ^j   Muller M ^k   Oette, M ^l   Hensel, M ^m   Thoden, J ⁿ   Fatkenheuer G ^d,o   Wyen, C ^d  

^a IPM Study Center   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c Harlaching Hospital   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f HEINRICH HEINE UNIVERSITY   (Germany)

^g Ifi Institute for Interdisciplinary Medicine   (Germany)

^h UNIVERSITY OF DUISBURG ESSEN   (Germany)

ⁱ UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^j Medical Center for Infectious Diseases (MIB)   (Germany)

^k Vivantes Auguste Viktoria Klinikum   (Germany)

^l Augustinerinnen Hospital   (Germany)

^m Hematology Oncology and Infectious Diseases Practice   (Germany)

ⁿ UNIVERSITY OF FREIBURG   (Germany)

^o German Centre for Infection Research (DZIF)   (Germany)

more..

Author keywords

AIDS related lymphoma; HIV associated Hodgkin lymphoma; HIV associated non Hodgkin lymphoma; HIV related Hodgkin lymphoma

Indexed keywords

ANTIRETROVIRUS AGENT; VIRUS RNA;

ADULT; AGED; ARTICLE; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; DRUG EXPOSURE; FEMALE; HODGKIN DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; VIRUS LOAD; CLINICAL TRIAL; COMPARATIVE STUDY; COMPLICATION; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; INCIDENCE; LYMPHOMA, AIDS-RELATED; MIDDLE AGED; MULTICENTER STUDY; PROSPECTIVE STUDY; RISK FACTOR;

ADULT; CD4 LYMPHOCYTE COUNT; HIV INFECTIONS; HIV-1; HUMANS; INCIDENCE; LYMPHOMA, AIDS-RELATED; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; VIRAL LOAD;

EID: 84924663599     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/hiv.12200     Document Type: Article

References (20)

1. Bonnet F, Burty C, Lewden C etal. Changes in cancer mortality among HIV-infected patients: the Mortalité 2005 Survey. Clin Infect Dis 2009; 48: 633-639.
2. Mocroft A, Katlama C, Johnson AM etal. AIDS across Europe, 1994-1998: the Eurosida study. Lancet 2000; 356: 291-296.
3. COHERE Study Group. Incidence and risk factors of HIV-related non-Hodgkin's lymphoma in the era of combination antiretroviral therapy: a European multicohort study. Antivir Ther 2009; 14: 1065-1074.
4. Franceschi S, Lise M, Clifford GM etal. Changing patterns of cancer incidence in the early- and late-HAART periods: the Swiss HIV Cohort Study. Br J Cancer 2010; 103: 416-422.
5. Simard EP, Pfeiffer RM, Engels EA. Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States. Cancer 2011; 117: 1089-1096.
6. Polesel J, Clifford GM, Rickenbach M etal. Non-Hodgkin lymphoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy. AIDS 2008; 22: 301-306.
7. Gérard L, Meignin V, Galicier L etal. Characteristics of non-Hodgkin lymphoma arising in HIV-infected patients with suppressed HIV replication. AIDS 2009; 23: 2301-2308.
8. Clifford GM, Polesel J, Rickenbach M etal. Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and HAART. J Natl Cancer Inst 2005; 97: 425-432.
9. Bohlius J, Schmidlin K, Boué F etal. HIV-1-related Hodgkin lymphoma in the era of combination antiretroviral therapy: incidence and evolution of CD4+ T-cell lymphocytes. Blood 2011; 117: 6100-6108.
10. Biggar RJ, Jaffe ES, Goedert JJ, Chaturvedi A, Pfeiffer R, Engels EA. Hodgkin lymphoma and immunodeficiency in persons with HIV/AIDS. Blood 2006; 108: 3786-3791.
11. Engels EA, Biggar RJ, Hall HI etal. Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer 2008; 123: 187-194.
12. Powles T, Robinson D, Stebbing J etal. Highly active antiretroviral therapy and the incidence of non-AIDS-defining cancers in people with HIV infection. J Clin Oncol 2009; 27: 884-890.
13. Wyen C, Jensen B, Hentrich M etal. Treatment of AIDS-related lymphomas: rituximab is beneficial even in severely immunosuppressed patients. AIDS 2012; 26: 457-464.
14. Hentrich M, Berger M, Wyen C etal. Stage-adapted treatment of HIV-associated Hodgkin Lymphoma: results of a prospective multicenter study. J Clin Oncol 2012; 30: 4117-4123.
15. Gloghini A, Carbone A. Why would the incidence of HIV-associated Hodgkin lymphoma increase in the setting of improved immunity? Int J Cancer 2007; 120: 2753-2754.
16. Guiguet M, Boué F, Cadranel J, Lang JM, Rosenthal E. Costagliola D, on behalf of the Clinical Epidemiology Group of the FHDH-ANRS CO4 cohort. Effect of immunodeficiency, HIV viral load, and antiretroviral therapy on the risk of individual malignancies (FHDH-ANRS CO4): a prospective cohort study. Lancet Oncol 2009; 10: 1152-2259.
17. Lanoy E, Rosenberg PS, Fily F etal. HIV-associated Hodgkin lymphoma during the first months on combination antiretroviral therapy. Blood 2011; 118: 44-49.
18. Gotti D, Danesi M, Calabresi A etal. Clinical characteristics, incidence, and risk factors of HIV-related Hodgkin lymphoma in the era of combination antiretroviral therapy. AIDS Patient Care STDS 2013; 27: 259-265.
19. Zoufaly A, Stellbrink HJ, an der Heiden MA etal. Cumulative HIV viremia during highly active antiretroviral therapy is a strong predictor of AIDS-related lymphoma. J Infect Dis 2009; 200: 79-87.
20. Zoufaly A, an der Heiden M, Marcus U etal. Late presentation for HIV diagnosis and care in Germany. HIV Med 2012; 13: 172-181.