Celox-coated gauze for the treatment of civilian penetrating trauma: A randomized clinical trial

Trauma Monthly

Volumn 20, Issue 1, 2015, Pages 42-46

  Hatamabadi, Hamid Reza ^a,b   Zarchi, Fatemeh Asayesh ^b   Kariman, Hamid ^b   Dolatabadi, Ali Arhami ^b   Tabatabaey, Ali ^c   Amini, Afshin ^b  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c QOM UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Hemostasis; Occlusive Dressing; Stab Wound

Indexed keywords

CHITOSAN;

ADULT; ARM INJURY; ARTICLE; BLEEDING; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EMERGENCY HEALTH SERVICE; FEMALE; FOOT INJURY; GAUZE DRESSING; HAND INJURY; HEMOSTASIS; HUMAN; INTERMETHOD COMPARISON; INTERVENTION STUDY; LEG INJURY; LIMB INJURY; MAJOR CLINICAL STUDY; MALE; OCCLUSIVE DRESSING; PENETRATING TRAUMA; PRESSURE DRESSING; RANDOMIZED CONTROLLED TRIAL; STAB WOUND; SYSTOLIC BLOOD PRESSURE; WOUND DRESSING;

EID: 84924630221     PISSN: 22517464     EISSN: 22517472     Source Type: Journal    
DOI: 10.5812/traumamon.23862     Document Type: Article

References (21)

1. Sauaia A, Moore FA, Moore EE, Moser KS, Brennan R, Read RA, et al. Epidemiology of trauma deaths: a reassessment. J Trauma. 1995; 38 (2): 185-93.
2. Mabry R, McManus JG. Prehospital advances in the management of severe penetrating trauma. Crit Care Med. 2008; 36 (7 Suppl): S258-66.
3. Atls Subcommittee , American College of Surgeons' Committee on T, International AWG. Advanced trauma life support (ATLS (R)): the ninth edition. J Trauma Acute Care Surg. 2013; 74 (5): 1363-6.
4. Alam HB, Burris D, DaCorta JA, Rhee P. Hemorrhage control in the battlefield: role of new hemostatic agents. Mil Med. 2005; 170 (1): 63-9.
5. Pusateri AE, Holcomb JB, Kheirabadi BS, Alam HB, Wade CE, Ryan KL. Making sense of the preclinical literature on advanced hemostatic products. J Trauma. 2006; 60 (3): 674-82.
6. Acheson EM, Kheirabadi BS, Deguzman R, Dick EJ, Holcomb JB. Comparison of hemorrhage control agents applied to lethal extremity arterial hemorrhages in swine. J Trauma. 2005; 59 (4): 865-74.
7. Kozen BG, Kircher SJ, Henao J, Godinez FS, Johnson AS. An alternative hemostatic dressing: comparison of CELOX, HemCon, and QuikClot. Acad Emerg Med. 2008; 15 (1): 74-81.
8. Devlin JJ, Kircher S, Kozen BG, Littlejohn LF, Johnson AS. Comparison of ChitoFlex (R), CELOX, and QuikClot (R) in control of hemorrhage. J Emerg Med. 2011; 41 (3): 237-45.
9. Littlejohn LF, Devlin JJ, Kircher SS, Lueken R, Melia MR, Johnson AS. Comparison of Celox-A, ChitoFlex, WoundStat, and combat gauze hemostatic agents versus standard gauze dressing in control of hemorrhage in a swine model of penetrating trauma. Acad Emerg Med. 2011; 18 (4): 340-50.
10. Sondeen JL, Pusateri AE, Coppes VG, Gaddy CE, Holcomb JB. Comparison of 10 different hemostatic dressings in an aortic injury. J Trauma. 2003; 54 (2): 280-5.
11. Koksal O, Ozdemir F, Cam Etoz B, Isbil Buyukcoskun N, Sigirli D. Hemostatic effect of a chitosan linear polymer (Celox (R) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy. Ulus Travma Acil Cerrahi Derg. 2011; 17 (3): 199-204.
12. Wedmore I, McManus JG, Pusateri AE, Holcomb JB. A special report on the chitosan-based hemostatic dressing: experience in current combat operations. J Trauma. 2006; 60 (3): 655-8.
13. Aktop S, Emekli-Alturfan E, Ozer C, Gonul O, Garip H, Yarat A, et al. Effects of Ankaferd Blood Stopper and Celox on the tissue factor activities of warfarin-treated rats. Clin Appl Thromb Hemost. 2014; 20 (1): 16-21.
14. Arul GS, Bowley DM, DiRusso S. The use of Celox gauze as an adjunct to pelvic Packing in otherwise uncontrollable pelvic haemorrhage secondary to penetrating trauma. J R Army Med Corps. 2012; 158 (4): 331-3.
15. Burgert J, Gegel B, Neal AR, Kammer KE, Paul ME, Schwartz DJ, et al. The effects of arterial blood pressure on rebleeding when BleedArrest, Celox and TraumaDex are used in a porcine model of lethal femoral injury. Mil Med. 2012; 177 (3): 340-4.
16. Burgert JM, Gegel BT, Austin R3, Davila A, Deeds J, Hodges L, et al. Effects of arterial blood pressure on rebleeding using Celox and TraumaDEX in a porcine model of lethal femoral injury. AANA J. 2010; 78 (3): 230-6.
17. Mendis D, Vesely M. Improvements in the management of trauma patients with the introduction of a lower limb trauma coordinator. Trauma Mon. 2012; 16 (4): 201-2.
18. Pozza M, Millner RW. Celox (chitosan) for haemostasis in massive traumatic bleeding: experience in Afghanistan. Eur J Emerg Med. 2011; 18 (1): 31-3.
19. Millner RW, Lockhart AS, Bird H, Alexiou C. A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery. Ann Thorac Surg. 2009; 87 (2): e13-4.
20. Bostrom L, Heinius G, Nilsson B. Trends in the incidence and severity of stab wounds in Sweden 1987-1994. Eur J Surg. 2000; 166 (10): 765-70.
21. Pallett JR, Sutherland E, Glucksman E, Tunnicliff M, Keep JW. A cross-sectional study of knife injuries at a London major trauma centre. Ann R Coll Surg Engl. 2014; 96 (1): 23-6.