Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+,K+-ATPase α2 activity

Journal of Physiology

Volumn 593, Issue 6, 2015, Pages 1509-1521

  Aronsen, J M ^a,b   Skogestad, J ^a,c   Lewalle, A ^d   Louch, W E ^a,c   Hougen, K ^a,c   Stokke, M K ^a,c   Swift, F ^a,c   Niederer, S ^d   Smith, N P ^d   Sejersted, O M ^a,c   Sjaastad, I ^a,c  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b BJØRKNES UNIVERSITY COLLEGE   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA2; CALCIUM ION; OUABAIN; POTASSIUM; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; UNCLASSIFIED DRUG; PROTEIN SUBUNIT;

ACTION POTENTIAL DURATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM OVERLOAD; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL STIMULATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART VENTRICLE; HEART VENTRICLE ARRHYTHMIA; HYPERPOLARIZATION; HYPOKALEMIA; MALE; MATHEMATICAL MODEL; METABOLIC DISORDER; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; SODIUM CELL LEVEL; ACTION POTENTIAL; ANIMAL; CELL CULTURE; CYTOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN SUBUNIT; WISTAR RAT;

ACTION POTENTIALS; ANIMALS; CALCIUM SIGNALING; CELLS, CULTURED; HEART VENTRICLES; HYPOKALEMIA; MALE; MYOCYTES, CARDIAC; POTASSIUM; PROTEIN SUBUNITS; RATS; RATS, WISTAR; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84924565565     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.279893     Document Type: Article

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