Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington’s disease

Journal of Neuroscience

Volumn 35, Issue 10, 2015, Pages 4440-4451

  Estrada Sánchez, Ana María ^a,c   Burroughs, Courtney L ^a   Cavaliere, Stephen ^a   Barton, Scott J ^a   Chen, Shirley ^a   William Yang, X ^b   Rebec, George V ^a  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BAC Cre; BACHD mice; Huntington s disease; In vivo electrophysiology; Motor cortex; Striatum

Indexed keywords

HUNTINGTIN; EMPTY SPIRACLES HOMEOBOX PROTEINS; HOMEODOMAIN PROTEIN; HUNTINGTON PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BEHAVIOR ASSESSMENT; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; CELL INTERACTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; FEMALE; GENOTYPE; HUNTINGTON CHOREA; MALE; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; SPIKE; SPIKE WAVE; STRIATE CORTEX; ACTION POTENTIAL; ANIMAL; BRAIN CORTEX; COMPLICATION; CONDITIONING; CORPUS STRIATUM; DISEASE MODEL; EFFERENT NERVE; ELECTROENCEPHALOGRAM; EXPLORATORY BEHAVIOR; GENETICS; LEARNING DISORDERS; NERVE CELL; NESTING; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; TRINUCLEOTIDE REPEAT;

ACTION POTENTIALS; ANIMALS; BRAIN WAVES; CEREBRAL CORTEX; CONDITIONING (PSYCHOLOGY); CORPUS STRIATUM; DISEASE MODELS, ANIMAL; EFFERENT PATHWAYS; EXPLORATORY BEHAVIOR; FEMALE; HOMEODOMAIN PROTEINS; HUNTINGTON DISEASE; LEARNING DISORDERS; MALE; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NESTING BEHAVIOR; NEURONS; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS; TRINUCLEOTIDE REPEATS;

EID: 84924447395     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2812-14.2015     Document Type: Article

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