MiR-133b Contributes to Arsenic-Induced Apoptosis in U251 Glioma Cells by Targeting the hERG Channel

Journal of Molecular Neuroscience

Volumn 55, Issue 4, 2015, Pages 985-994

  Wang, Jian ^a   Li, Yongli ^a   Jiang, Chuanlu ^a  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Arsenic trioxide; Glioma; hERG; miR 133b; miR 34a

Indexed keywords

ARSENIC TRIOXIDE; MICRORNA; MICRORNA 34A; MIRNA 133B; POTASSIUM CHANNEL HERG; SERUM RESPONSE FACTOR; UNCLASSIFIED DRUG; ERG1 POTASSIUM CHANNEL; MIRN133 MICRORNA, HUMAN; MIRN34 MICRORNA, HUMAN; ORGANOARSENIC DERIVATIVE; OXIDE;

APOPTOSIS; ARTICLE; BIOINFORMATICS; CANCER CHEMOTHERAPY; CANCER PATIENT; CELL CULTURE; CELL VIABILITY; ELECTRON MICROSCOPY; GENE EXPRESSION; GENETIC TRANSFECTION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LUCIFERASE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; DRUG EFFECTS; GENETICS; GLIOMA; METABOLISM; NERVE CELL; TUMOR CELL LINE;

APOPTOSIS; ARSENICALS; CELL LINE, TUMOR; CELLS, CULTURED; ETHER-A-GO-GO POTASSIUM CHANNELS; GLIOMA; HUMANS; MICRORNAS; NEURONS; OXIDES;

EID: 84924370624     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0455-8     Document Type: Article

References (30)

1. Asher V, Sowter H, Shaw R, Bali A, Khan R (2010) Eag and HERG potassium channels as novel therapeutic targets in cancer. World J Surg Oncol 8:113
2. Asher V, Warren A, Shaw R, Sowter H, Bali A, Khan R (2011) The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. Cancer Cell Int 11:6
3. Bai Y, Liao H, Liu T, Zeng X, Xiao F, Luo L, Guo H, Guo L (2013) MiR-296-3p regulates cell growth and multi-drug resistance of human glioblastoma by targeting ether-a-go-go (EAG1). Eur J Cancer 49:710–724
4. Chu W, Li C, Qu X, Zhao D, Wang X, Yu X, Cai F, Liang H, Zhang Y, Zhao X, Li B, Qiao G, Dong D, Lu Y, Du Z, Yang B (2012) Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome. Cardiovasc Res 96:90–98
5. Cohen KJ, Gibbs IC, Fisher PG, Hayashi RJ, Macy ME, Gore L (2013) A phase I trial of arsenic trioxide chemoradiotherapy for infiltrating astrocytomas of childhood. Neuro Oncol 15:783–787
6. Ficker E, Kuryshev YA, Dennis AT, Obejero-Paz C, Wang L, Hawryluk P, Wible BA, Brown AM (2004) Mechanisms of arsenic-induced prolongation of cardiac repolarization. Mol Pharmacol 66:33–44
7. Gonzalez-Juanatey JR, Iglesias MJ, Alcaide C, Pineiro R, Lago F (2003) Doxazosin induces apoptosis in cardiomyocytes cultured in vitro by a mechanism that is independent of alpha1-adrenergic blockade. Circulation 107:127–131
8. Grimm SA, Marymont M, Chandler JP, Muro K, Newman SB, Levy RM, Jovanovic B, McCarthy K, Raizer JJ (2012) Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas. J Neurooncol 110:237–243
9. He JH, Li YM, Li YG, Xie XY, Wang L, Chun SY, Cheng WJ (2013) hsa-miR-203 enhances the sensitivity of leukemia cells to arsenic trioxide. Exp Ther Med 5:1315–1321
10. Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D (2008) MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell 2:219–229
11. Kanzawa T, Zhang L, Xiao L, Germano IM, Kondo Y, Kondo S (2005) Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3. Oncogene 24:980–991
12. Koshkin PA, Chistiakov DA, Chekhonin VP (2013) Role of microRNAs in mechanisms of glioblastoma resistance to radio- and chemotherapy. Biochemistry (Mosc) 78:325–334
13. Li Y, Guessous F, Zhang Y, Dipierro C, Kefas B, Johnson E, Marcinkiewicz L, Jiang J, Yang Y, Schmittgen TD, Lopes B, Schiff D, Purow B, Abounader R (2009) MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res 69:7569–7576
14. Lin H, Li Z, Chen C, Luo X, Xiao J, Dong D, Lu Y, Yang B, Wang Z (2011) Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether a go-go K + channel. PLoS One 6:e20362
15. Liu L, Shao X, Gao W, Zhang Z, Liu P, Wang R, Huang P, Yin Y, Shu Y (2012) MicroRNA-133b inhibits the growth of non-small-cell lung cancer by targeting the epidermal growth factor receptor. FEBS J 279:3800–3812
16. Luan S, Sun L, Huang F (2010) MicroRNA-34a: a novel tumor suppressor in p53-mutant glioma cell line U251. Arch Med Res 41:67–74
17. Masi A, Becchetti A, Restano-Cassulini R, Polvani S, Hofmann G, Buccoliero AM, Paglierani M, Pollo B, Taddei GL, Gallina P, Di Lorenzo N, Franceschetti S, Wanke E, Arcangeli A (2005) hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines. Br J Cancer 93:781–792
18. Patil SA, Hosni-Ahmed A, Jones TS, Patil R, Pfeffer LM, Miller DD (2013) Novel approaches to glioma drug design and drug screening. Expert Opin Drug Discov 8:1135–1151
19. Patron JP, Fendler A, Bild M, Jung U, Muller H, Arntzen MO, Piso C, Stephan C, Thiede B, Mollenkopf HJ, Jung K, Kaufmann SH, Schreiber J (2012) MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis. PLoS One 7:e35345
20. Primon M, Huszthy PC, Motaln H, Talasila KM, Torkar A, Bjerkvig R, Lah Turnsek T (2013) Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids. Exp Cell Res 319:2637–2648
21. Qin W, Dong P, Ma C, Mitchelson K, Deng T, Zhang L, Sun Y, Feng X, Ding Y, Lu X, He J, Wen H, Cheng J (2012) MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways. Oncogene 31:4067–4075
22. Shan H, Zhang Y, Cai B, Chen X, Fan Y, Yang L, Chen X, Liang H, Zhang Y, Song X, Xu C, Lu Y, Yang B, Du Z (2013) Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling. Int J Cardiol 167:2798–2805
23. Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG (2008) miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 6:14
24. Villar AV, Merino D, Wenner M, Llano M, Cobo M, Montalvo C, Garcia R, Martin-Duran R, Hurle JM, Hurle MA, Nistal JF (2011) Myocardial gene expression of microRNA-133a and myosin heavy and light chains, in conjunction with clinical parameters, predict regression of left ventricular hypertrophy after valve replacement in patients with aortic stenosis. Heart 97:1132–1137
25. Wang Y, Jiang T (2013) Understanding high grade glioma: molecular mechanism, therapy and comprehensive management. Cancer Lett 331:139–146
26. Wu Y, Li XF, Yang JH, Liao XY, Chen YZ (2012) microRNAs expression profile in acute promyelocytic leukemia cell differentiation induced by all-trans retinoic acid and arsenic trioxide. Zhonghua Xue Ye Xue Za Zhi 33:546–551
27. Xin H, Li Y, Buller B, Katakowski M, Zhang Y, Wang X, Shang X, Zhang ZG, Chopp M (2012) Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth. Stem Cells 30:1556–1564
28. Xin H, Li Y, Liu Z, Wang X, Shang X, Cui Y, Gang Zhang Z, Chopp M (2013) Mir-133b Promotes Neural Plasticity and Functional Recovery after Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles. Stem Cells
29. Zhang Y, Xiao J, Wang H, Luo X, Wang J, Villeneuve LR, Zhang H, Bai Y, Yang B, Wang Z (2006) Restoring depressed HERG K + channel function as a mechanism for insulin treatment of abnormal QT prolongation and associated arrhythmias in diabetic rabbits. Am J Physiol Heart Circ Physiol 291:H1446–H1455
30. Zhao H, Lai F, Nonn L, Brooks JD, Peehl DM (2005) Molecular targets of doxazosin in human prostatic stromal cells. Prostate 62:400–410