Roles of individual disulfide bridges in the conformation and activity of μ-conotoxin GIIIA, a peptide blocker of muscle sodium channels

International Journal of Peptide Research and Therapeutics

Volumn 20, Issue 2, 2014, Pages 253-258

  Sato, Kazuki ^a   Yamaguchi, Yoko ^a   Ishida, Yukisato ^b  

^a FUKUOKA WOMEN'S UNIVERSITY   (Japan)

^b BUNKYO GAKUIN UNIVERSITY   (Japan)

Author keywords

Disulfide bond; Sodium channel; Structure activity relation; Conotoxin GIIIA

Indexed keywords

CONOTOXIN; L CONOTOXIN GIIIA 2A1; L CONOTOXIN GIIIA 2A2; L CONOTOXIN GIIIA 2A3; L CONOTOXIN GIIIA 4A12; L CONOTOXIN GIIIA 4A13; L CONOTOXIN GIIIA 4A23; L CONOTOXIN GIIIA 6A; L CONOTOXIN GIIIA DERIVATIVE; SODIUM CHANNEL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANALYTICAL PARAMETERS; ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; DISULFIDE BOND; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PEPTIDE SYNTHESIS; PROTEIN CONFORMATION; RETENTION TIME; STRUCTURE ACTIVITY RELATION;

EID: 84924353392     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-013-9389-1     Document Type: Article

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