Garcinia kola seed ameliorates renal, hepatic, and testicular oxidative damage in streptozotocin-induced diabetic rats

Pharmaceutical Biology

Volumn 53, Issue 5, 2015, Pages 695-704

  Adedara, Isaac A ^a   Awogbindin, Ifeoluwa O ^a   Anamelechi, Joy P ^a   Farombi, Ebenezer O ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Antioxidant; Endocrine; Folklore medicine; Hyperglycemia; Lipid peroxidation

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CORN OIL; CREATININE; FOLLITROPIN; GLUCOSE; LIOTHYRONINE; LUTEINIZING HORMONE; PLANT MEDICINAL PRODUCT; STREPTOZOCIN; TESTOSTERONE; THYROXINE; UREA; PLANT EXTRACT;

AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DRUG EFFECT; ENZYME ACTIVITY; FOLLITROPIN BLOOD LEVEL; GARCINIA KOLA; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERGLYCEMIA; KIDNEY FUNCTION; KIDNEY INJURY; LIOTHYRONINE BLOOD LEVEL; LIPID PEROXIDATION; LIVER FUNCTION; LIVER INJURY; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NONHUMAN; OXIDATIVE STRESS; PLANT SEED; RAT; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS INJURY; TESTOSTERONE BLOOD LEVEL; THYROXINE BLOOD LEVEL; TREATMENT DURATION; UREA BLOOD LEVEL; ANIMAL; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ISOLATION AND PURIFICATION; KIDNEY; LIVER; METABOLISM; PHYSIOLOGY; TESTIS; WISTAR RAT;

CLUSIACEAE; GARCINIA KOLA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; GARCINIA KOLA; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; SEEDS; TESTIS;

EID: 84924352751     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2014.937504     Document Type: Article

References (56)

1. Adaramoye OA, Adeyemi EO. (2006). Hypoglycaemic and hypolipi-daemic effects of fractions from kolaviron, a biflavonoid complex from Garcinia kola in streptozotocin-induced diabetes mellitus rats. J Pharm Pharmacol 58:121-8.
2. Adedara IA, Farombi EO. (2010). Induction of oxidative damage in the testes and spermatozoa and hematotoxicity in rats exposed to multiple doses of ethylene glycol monoethyl ether. Hum Exp Toxicol 29: 801-12.
3. Adedara IA, Farombi EO. (2012). Chemoprotection of ethylene glycol monoethyl ether-induced reproductive toxicity in male rats by kolaviron, isolated biflavonoid from Garcinia kola seed. Hum Exp Toxicol 31:506-17.
4. Adedara IA, Farombi EO. (2013). Influence of kolaviron and vitamin E on ethylene glycol monoethyl ether-induced haematotoxicity and renal apoptosis in rats. Cell Biochem Function 32:31-8.
5. Adesuyi AO, Elumm IK, Adaramola FB, Nwokocha AGM. (2012). Nutritional and phytochemical screening of Garcinia kola. Adv J Food Sci Tech 4:9-14.
6. Amann RP, Johnson L, Thompson DL, Pickett BW. (1976). Daily spermatozoal production, epididymal spermatozoal reserves and transit time of spermatozoa through the epididymis of the rhesus monkey. Biol Reprod 15:586-92.
7. Baynes JW, Thorpe SR. (1999). Role of oxidative stress in diabetic complications: A new perspective on an old paradigm. Diabetes 48: 1-9.
8. Clairborne A. (1995). Catalase activity. In: Greewald AR, ed. Handbook of Methods for Oxygen Radical Research. Boca Raton: CRC Press, 237-42.
9. Cemek M, Kaga S, Simsek N, et al. (2008). Antihyperglycemic and antioxidative potential of Matricaria chamomilla L. in streptozotocin-induced diabetic rats. J Nat Med 62:284-93.
10. Demir E, Kaya B, Soriano C, et al. (2011). Genotoxic analysis of four lipid-peroxidation products in the mouse lymphoma assay. Mutat Res 726:98-103.
11. den Hollander JG, Wulkan RW, Mantel MJ, Berghout A. (2005). Correlation between severity of thyroid dysfunction and renal function. Clinic Endocrinol 62:423-7.
12. Duze BN, Sewani-Rusike CR, Nkeh-Chungag BN. (2012). Effects of an ethanolic extract of Garcinia kola on glucose and lipid levels in streptozotocin induced diabetic rats. Afr J Biotech 11:8309-15.
13. Farombi EO, Adedara IA, Oyenihi AB, et al. (2013). Hepatic, testicular and spermatozoa antioxidant status in rats chronically treated with Garcinia kola seed. J Ethnopharmacol 146:536-42.
14. Farombi EO, Tahnteng JG, Agboola AO, et al. (2000). Chemoprevention of 2-acetylaminofluorene-induced hepatotoxicity and lipid peroxida-tion in rats by kolaviron- A Garcinia kola seed extract. Food Chem Toxicol 38:535-41.
15. Fawcett JK, Scott JE. (1960). Rapid and precise method for the determination of urea. J Clinic Pathol 13:156-8.
16. Ghule AE, Jadhav SS, Bodhankar SL. (2012). Trigonelline ameliorates diabetic hypertensive nephropathy by suppression of oxidative stress in kidney and reduction in renal cell apoptosis and fibro-sis in streptozotocin induced neonatal diabetic (nSTZ) rats. Int Immunopharmacol 14:740-8.
17. Gopinath B, Harris DC, Wall JR, et al. (2013). Relationship between thyroid dysfunction and chronic kidney disease in community-dwelling older adults. Maturitas 75:159-64.
18. Halliwell B. (2007). Biochemistry of oxidative stress. Biochem Soc Transact 35:1147-50.
19. Harrison SA. (2006). Liver disease in patients with diabetes mellitus. J Clinic Gastroenterol 40:68-76.
20. Henry RJ. (1974). Clinical Chemistry, Principles and Techniques, 2nd ed. Hagerstown (MD): Harper and Row, 525.
21. Hess RA. (1990). Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: Light microscopic observations of perfusion-fixed and plastic-embedded testes. Biol Reprod 43:525-42.
22. Iglesias P, Déiez JJ. (2009). Thyroid dysfunction and kidney disease. Euro J Endocrinol 160:503-15.
23. Iwu MM. (1993). Handbook of African Medicinal Plants. CRC Press: London, 183-4.
24. Iwu MM, Igboko OA, Okunji CO, Tempesta MS. (1990). Antidiabetic and aldose reductase activities of Biflavanones of Garcinia kola. J Pharm Pharmacol 42:290-2.
25. Jelodar G, Khaksar Z, Pourahmadi M. (2010). Endocrine profile and testicular histomorphometry in neonatal rats of diabetic mothers. Veterinarski Arhiv 80:421-30.
26. Jendrassik LP, Grof P. (1983). Vereinfachte photometrische methoden zur bestimmung des blutbilirubins. Biochem Zeitschr Band 297:81-9.
27. Johnson F, Giulivi C. (2005). Superoxide dismutases and their impact upon human health. Mol Aspects Med 26:340-52.
28. Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR. (1974). Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3, 4 bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11:151-69.
29. Joyce KL, Porcelli J, Cooke PS. (1993). Neonatal goitrogen treatment increases adult testes size and sperm production in the mouse. J Androl 14:448-55.
30. Kaplan MM. (1993). Laboratory tests. In: Schiff L, Schiff ER, eds. Diseases of the Liver, 7th ed. Philadelphia: JB Lippincott, 108-44.
31. Kohen R, Nyska A. (2002). Oxidation of biological systems: Oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol 30:620-50.
32. La Vignera S, Calogero AE, Condorelli R, et al. (2009). Andrological characterization of the patient with diabetes mellitus. Minerva Endocrinol 34:1-9.
33. Loeb JN. (1996). Metabolic changes in thyrotoxicosis. In: Braverman LE, Utiger RD, Ingbar SH, Werner SC, eds. Werner and Ingbar's the Thyroid: A Fundamental and Clinical Text, 7th ed. Philadelphia: Lippincott Williams & Wilkins, 687-93.
34. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with Folin phenol reagent. J Biol Chem 193:265-75.
35. Mazzini F, Betti M, Netscher T, et al. (2009). Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia kola seeds. Chirality 21:519-24.
36. Misra HP, Fridovich I. (1972). The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247:3170-5.
37. Montenegro J, Gonzalez O, Saracho R, et al. (1996). Changes in renal function in primary hypothyroidism. Am J Kidney Dis 27:195-8.
38. Muthuvel R, Venkataraman P, Krishnamoorthy G, et al. (2006). Antioxidant effect of ascorbic acid on PCB (Aroclor 1254) induced oxidative stress in hypothalamus of albino rats. Clin Chim Acta 365: 297-303.
39. Nanjappa MK, Simon L, Akingbemi BT. (2012). The industrial chemical bisphenol A (BPA) interferes with proliferative activity and development of steroidogenic capacity in rat Leydig cells. Biol Reprod 86: 1-12.
40. Okoko T. (2009). In vitro antioxidant and free radical scavenging activities of Garcinia kola seeds. Food Chem Toxicol 47:2620-3.
41. Omage K, Erifeta OG, Uhunmwangho SE, et al. (2011). Evaluation of hypoglycemic and antioxidative properties of aqueous extract of Garcinia kola seeds in Wistar rats. Curr Res J Biol Sci 3:326-9.
42. Pant N, Srivastava SP. (2003). Testicular and spermatotoxic effects of quinalphos in rats. J Appl Toxicol 23:271-4.
43. Pompella A, Visvikis A, Paolicchi A, et al. (2003). The changing faces of glutathione, a cellular protagonist. Biochem Pharmacol 66:1499-503.
44. Ralebona N, Sewani-Rusike CR, Nkeh-Chungag, BN. (2012). Effects of ethanolic extract of Garcinia kola on sexual behaviour and sperm parameters in male Wistar rats. Afr J Pharm Pharmacol 6: 1077-82.
45. Rashid K, Das J, Sil PC. (2013). Taurine ameliorate alloxan induced oxidative stress and intrinsic apoptotic pathway in the hepatic tissue of diabetic rats. Food Chem Toxicol 51:317-29.
46. Recommendation of German Society of Clinical Chemistry (Rec. GSCC). (1972). Optimised standard colorimetric methods. J Clinic Chem Clinic Biochem 10:182-3.
47. Reitmann S, Frankel S. (1957). Colorimetric method for the determination of serum transaminase activity. Am J Clinic Pathol 28:56-68.
48. Saravanan G, Ponmurugan P. (2012). Antidiabetic effect of S-allylcysteine: Effect on thyroid hormone and circulatory antioxidant system in experimental diabetic rats. J Diabetes Complicat 26:280-5.
49. Schoeller EL, Albanna G, Frolova AI, Moley KH. (2012). Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary-gonadal axis in Akita diabetic mice and restores male fertility. Diabetes 61: 1869-78.
50. Shang G, Gao P, Zhao Z, et al. (2013). 3, 5-Diiodo-L-thyronine ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats. Biochim Biophys Acta 1832:674-84.
51. Terashima K, Takawa Y, Niwa M. (2002). Powerful antioxidative agents based on garcinoic acid from Garcinia kola. Bioorg Med Chem 10: 1619-25.
52. Wells ME, Awa OA. (1970). New technique for assessing acrosomal characteristics of spermatozoa. J Dairy Sci 53:226-7.
53. Wolff SP. (1994). Ferrous ion oxidation in the presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods Enzymol 233:182-9.
54. Yu T, Robotham JL, Yoon Y. (2006). Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci USA 103:2653-8.
55. Zafar M, Naqvi SN. (2010). Effects of STZ-induced diabetes on the relative weights of kidney, liver and pancreas in albino rats: A comparative study. Int J Morphol 28:135-42.
56. Zemjanis R. (1970). Collection and evaluation of semen. In: Zemjanis R, ed. Diagnostic and Therapeutic Technique in Animal Reproduction, 2nd ed. Baltimore (MD): William and Wilkins Company, 139-53.