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Volumn 55, Issue 2, 2015, Pages e72-e86

Hepatitis C therapy: Looking toward interferon-sparing regimens

Author keywords

[No Author keywords available]

Indexed keywords

BOCEPREVIR; PEGINTERFERON; RIBAVIRIN; SIMEPREVIR; SOFOSBUVIR; TELAPREVIR; ANTIVIRUS AGENT; INTERFERON;

EID: 84924348161     PISSN: 15443191     EISSN: 15443450     Source Type: Journal    
DOI: 10.1331/JAPhA.2015.15508     Document Type: Review
Times cited : (9)

References (54)
  • 1
    • 84872650467 scopus 로고    scopus 로고
    • Geneva, Switzerland: World Health Organization Accessed July 24, 2014
    • Hepatitis C. Fact Sheet No. 164. Geneva, Switzerland: World Health Organization. www.who.int/mediacentre/factsheets/fs164/en/. Accessed July 24, 2014.
    • Fact Sheet No. 164
  • 2
    • 33646852746 scopus 로고    scopus 로고
    • The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
    • 2006
    • Armstrong GL, Wasley A, Simard EP, et al. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med. 2006;144(10):705-714.
    • Ann Intern Med , vol.144 , Issue.10 , pp. 705-714
    • Armstrong, G.L.1    Wasley, A.2    Simard, E.P.3
  • 4
    • 84857144025 scopus 로고    scopus 로고
    • The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007
    • Ly KN, Xing J, Klevens RM, et al. The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007. Ann Intern Med. 2012;156:271-278.
    • (2012) Ann Intern Med , vol.156 , pp. 271-278
    • Ly, K.N.1    Xing, J.2    Klevens, R.M.3
  • 5
    • 84867299184 scopus 로고    scopus 로고
    • HIV coinfection with hepatitis C virus: Evolving epidemiology and treatment paradigms
    • Taylor LE, Swan T, Mayer KH. HIV coinfection with hepatitis C virus: evolving epidemiology and treatment paradigms. Clin Infect Dis. 2012;55:S33-S42.
    • (2012) Clin Infect Dis , vol.55 , pp. S33-S42
    • Taylor, L.E.1    Swan, T.2    Mayer, K.H.3
  • 6
    • 84867321665 scopus 로고    scopus 로고
    • Evolving epidemiology of hepatitis C virus in the United States
    • Klevens RM, Hu DJ, Jiles R, et al. Evolving epidemiology of hepatitis C virus in the United States. Clin Infect Dis. 2012;55:S3-S9.
    • (2012) Clin Infect Dis , vol.55 , pp. S3-S9
    • Klevens, R.M.1    Hu, D.J.2    Jiles, R.3
  • 7
    • 84893559399 scopus 로고    scopus 로고
    • The risk of long-term morbidity and mortality in patients with chronic hepatitis C: Results from an analysis of data from a Department of Veterans Affairs Clinical Registry
    • McCombs J, Matsuda T, Tonnu-Mihara I. The risk of long-term morbidity and mortality in patients with chronic hepatitis C: results from an analysis of data from a Department of Veterans Affairs Clinical Registry. JAMA Intern Med. 2014;174:204-212.
    • (2014) JAMA Intern Med , vol.174 , pp. 204-212
    • McCombs, J.1    Matsuda, T.2    Tonnu-Mihara, I.3
  • 8
    • 84902548335 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to new specifically targeted antiviral therapy: A public health perspective
    • Salvatierra K, Fareleski S, Forcada A, et al. Hepatitis C virus resistance to new specifically targeted antiviral therapy: a public health perspective. World J Virol. 2013;2:6-15.
    • (2013) World J Virol , vol.2 , pp. 6-15
    • Salvatierra, K.1    Fareleski, S.2    Forcada, A.3
  • 9
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 2009;461:399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 10
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pre-treatment predictor of sustained virologic response in hepatitis C virus
    • Thompson AJ, Muir AJ, Sulkowski MS, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pre-treatment predictor of sustained virologic response in hepatitis C virus. Gastroenterology. 2010;139:120-9.
    • (2010) Gastroenterology , vol.139 , pp. 120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3
  • 11
    • 78951477270 scopus 로고    scopus 로고
    • Direct economic burden of chronic hepatitis C virus in a United States managed care population
    • Davis KL, Mitra D, Medjedovic J, et al. Direct economic burden of chronic hepatitis C virus in a United States managed care population. J Clin Gastroenterol. 2011;45:e17-e24.
    • (2011) J Clin Gastroenterol , vol.45 , pp. e17-e24
    • Davis, K.L.1    Mitra, D.2    Medjedovic, J.3
  • 12
    • 84902104150 scopus 로고    scopus 로고
    • Virus-related liver cirrhosis: Molecular basis and therapeutic options
    • Lin J, Wu J, Zhang Q, et al. Virus-related liver cirrhosis: molecular basis and therapeutic options. World J Gastroenterol. 2014;20(21):6457-6469.
    • (2014) World J Gastroenterol , vol.20 , Issue.21 , pp. 6457-6469
    • Lin, J.1    Wu, J.2    Zhang, Q.3
  • 13
    • 0037342870 scopus 로고    scopus 로고
    • The mechanisms that control intracellular penetration of the HIV protease inhibitors
    • Hoggard PG, Owen A. The mechanisms that control intracellular penetration of the HIV protease inhibitors. J Antimicrob Chemother. 2003;51:493-496.
    • (2003) J Antimicrob Chemother , vol.51 , pp. 493-496
    • Hoggard, P.G.1    Owen, A.2
  • 14
    • 84897564568 scopus 로고    scopus 로고
    • How hepatitis C virus invades hepatocytes: The mystery of viral entry
    • Zhu YZ, Qian XJ, Zhao P, et al. How hepatitis C virus invades hepatocytes: the mystery of viral entry. World J Gastroenterol. 2014;20:3457-3467.
    • (2014) World J Gastroenterol , vol.20 , pp. 3457-3467
    • Zhu, Y.Z.1    Qian, X.J.2    Zhao, P.3
  • 15
    • 84880938142 scopus 로고    scopus 로고
    • Hepatitis C virus- related hepatocellular carcinoma: An insight into molecular mechanisms and therapeutic strategies
    • Selimovic D, El-Khattouti A, Ghozlan H, et al. Hepatitis C virus- related hepatocellular carcinoma: an insight into molecular mechanisms and therapeutic strategies. World J Hepatol. 2012;4:342-355.
    • (2012) World J Hepatol , vol.4 , pp. 342-355
    • Selimovic, D.1    El-Khattouti, A.2    Ghozlan, H.3
  • 16
    • 84855742665 scopus 로고    scopus 로고
    • Association between hepatitis C and hepatocellular carcinoma
    • Andrade LJ, D'Oliveira A, Melo RC, et al. Association between hepatitis C and hepatocellular carcinoma. J Glob Infect Dis. 2009;1:33-37.
    • (2009) J Glob Infect Dis , vol.1 , pp. 33-37
    • Andrade, L.J.1    D'Oliveira, A.2    Melo, R.C.3
  • 17
    • 84924416368 scopus 로고    scopus 로고
    • Hepatitis C FAQs for health professionals
    • Accessed July 31, 2014
    • Hepatitis C FAQs for health professionals. Centers for Disease Control and Prevention. www.cdc.gov/hepatitis/HCV/HCVfaq.htm. Accessed July 31, 2014.
    • Centers for Disease Control and Prevention
  • 18
    • 0038575483 scopus 로고    scopus 로고
    • Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
    • Gerlach JT, Diepolder HM, Zachoval R, et al. Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance. Gastroenterology. 2003;125:80-88.
    • (2003) Gastroenterology , vol.125 , pp. 80-88
    • Gerlach, J.T.1    Diepolder, H.M.2    Zachoval, R.3
  • 19
    • 80055020919 scopus 로고    scopus 로고
    • The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: An international study of 2411 cases
    • Sebastinani G, Castera L, Halfon P, et al. The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases. Aliment Pharmacol Ther. 2011;34:1202-1216.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 1202-1216
    • Sebastinani, G.1    Castera, L.2    Halfon, P.3
  • 20
    • 0036792679 scopus 로고    scopus 로고
    • Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection
    • abstract
    • Regev A, Berho M, Jeffers LJ, et al. Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection [abstract]. Am J Gastroenterol. 2002;97:2614-2618.
    • (2002) Am J Gastroenterol , vol.97 , pp. 2614-2618
    • Regev, A.1    Berho, M.2    Jeffers, L.J.3
  • 21
    • 61849120770 scopus 로고    scopus 로고
    • Review article: Investigational agents for chronic hepatitis C
    • Thompson AJ, McHutchison JG. Review article: investigational agents for chronic hepatitis C. Aliment Pharmacol Ther. 2009;29:689-705.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 689-705
    • Thompson, A.J.1    McHutchison, J.G.2
  • 23
    • 57449108564 scopus 로고    scopus 로고
    • Alcohol and viral hepatitis: A mini-review
    • Gitto S, Micco L, Conti F, et al. Alcohol and viral hepatitis: a mini-review. Dig Liver Dis. 2009;41:67-70.
    • (2009) Dig Liver Dis , vol.41 , pp. 67-70
    • Gitto, S.1    Micco, L.2    Conti, F.3
  • 24
    • 85030394976 scopus 로고    scopus 로고
    • Nutley, NJ: Hoffmann-La Roche, Inc.
    • Pegasys [product labeling]. Nutley, NJ: Hoffmann-La Roche, Inc.; 2002.
    • (2002) Pegasys [Product Labeling]
  • 25
    • 85030390942 scopus 로고    scopus 로고
    • Kenilworth, NJ: Schering Corp.
    • Peg-Intron [product labeling]. Kenilworth, NJ: Schering Corp.; 2001.
    • (2001) Peg-Intron [Product Labeling]
  • 26
    • 84924416365 scopus 로고    scopus 로고
    • South San Francisco, CA: Genentech USA, Inc.
    • Copegus [product labeling]. South San Francisco, CA: Genentech USA, Inc.; 2011.
    • (2011) Copegus [Product Labeling]
  • 27
    • 85030387668 scopus 로고    scopus 로고
    • Whitehouse Station, NJ: Merck & Co, Inc.
    • Rebetol [product labeling]. Whitehouse Station, NJ: Merck & Co, Inc.; 2013.
    • (2013) Rebetol [Product Labeling]
  • 28
    • 85030401700 scopus 로고    scopus 로고
    • Whitehouse Station, NJ: Merck & Co, Inc.
    • Victrelis [product labeling]. Whitehouse Station, NJ: Merck & Co, Inc.; 2011.
    • (2011) Victrelis [Product Labeling]
  • 29
    • 84924416362 scopus 로고    scopus 로고
    • Cambridge, MA: Vertex Pharmaceuticals, Inc.
    • Incivek [product labeling]. Cambridge, MA: Vertex Pharmaceuticals, Inc.; 2013.
    • (2013) Incivek [Product Labeling]
  • 30
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med. 2011;364:1195-1206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone, J.2    Bacon, B.R.3
  • 31
    • 84865494240 scopus 로고    scopus 로고
    • Factors that predict response of patients with hepatitis C virus infection to boceprevir
    • Poordad F, Bronowicki JP, Gordon SC, et al. Factors that predict response of patients with hepatitis C virus infection to boceprevir. Gastroenterology. 2012;143:608-618.e1-e5.
    • (2012) Gastroenterology , vol.143
    • Poordad, F.1    Bronowicki, J.P.2    Gordon, S.C.3
  • 32
    • 84905503101 scopus 로고    scopus 로고
    • Boceprevir and telaprevir- based triple therapy for chronic hepatitis C: Virological efficacy and impact on kidney function and model for end-stage liver disease score
    • Virlogeux V, Pradat P, Bailly F, et al. Boceprevir and telaprevir- based triple therapy for chronic hepatitis C: virological efficacy and impact on kidney function and model for end-stage liver disease score. J Viral Hepat. 2014;2:e98-e107.
    • (2014) J Viral Hepat , vol.2 , pp. e98-e107
    • Virlogeux, V.1    Pradat, P.2    Bailly, F.3
  • 33
    • 84897372446 scopus 로고    scopus 로고
    • Telaprevir or boceprevir- based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure
    • Macartney MJ, Irish D, Bridge SH, et al. Telaprevir or boceprevir- based therapy for chronic hepatitis C infection: development of resistance-associated variants in treatment failure. Antiviral Res. 2014;105:112-117.
    • (2014) Antiviral Res , vol.105 , pp. 112-117
    • Macartney, M.J.1    Irish, D.2    Bridge, S.H.3
  • 34
    • 84924416361 scopus 로고    scopus 로고
    • Titusville, NJ: Janssen Therapeutics, LP
    • Olysio [product labeling]. Titusville, NJ: Janssen Therapeutics, LP; 2013.
    • (2013) Olysio [Product Labeling]
  • 35
    • 84901508513 scopus 로고    scopus 로고
    • New treatments for genotype 1 chronic hepatitis C - Focus on simeprevir
    • Kanda T, Nakamoto S, Wu S. New treatments for genotype 1 chronic hepatitis C - focus on simeprevir. Ther Clin Risk Manag. 2014;10:387-394.
    • (2014) Ther Clin Risk Manag , vol.10 , pp. 387-394
    • Kanda, T.1    Nakamoto, S.2    Wu, S.3
  • 36
    • 84901217985 scopus 로고    scopus 로고
    • Simeprevir with peginterferon and ribavirin leads to high rates of SVR in patients with HCV genotype 1 who relapsed after previous therapy: A phase 3 trial
    • Forns X, Lawitz E, Zeuzem S, et al. Simeprevir with peginterferon and ribavirin leads to high rates of SVR in patients with HCV genotype 1 who relapsed after previous therapy: a phase 3 trial. Gastroenterology. 2014;146:1669-1679.e3.
    • (2014) Gastroenterology , vol.146 , pp. 1669-1679.e3
    • Forns, X.1    Lawitz, E.2    Zeuzem, S.3
  • 37
    • 85030398145 scopus 로고    scopus 로고
    • Foster City, CA: Gilead Sciences, Inc.
    • Sovaldi [product labeling]. Foster City, CA: Gilead Sciences, Inc.; 2013.
    • (2013) Sovaldi [Product Labeling]
  • 38
    • 84877730954 scopus 로고    scopus 로고
    • Sofosbuvir for previously untreated chronic hepatitis C infection
    • Lawitz E, Mangia A, Wyles D, et al. Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med. 2013;368:1878-1887.
    • (2013) N Engl J Med , vol.368 , pp. 1878-1887
    • Lawitz, E.1    Mangia, A.2    Wyles, D.3
  • 39
    • 84877739274 scopus 로고    scopus 로고
    • Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options
    • Jacobson IM, Gordon SC, Kowdley KV, et al. Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options. N Engl J Med. 2013;368:1867-1877.
    • (2013) N Engl J Med , vol.368 , pp. 1867-1877
    • Jacobson, I.M.1    Gordon, S.C.2    Kowdley, K.V.3
  • 41
    • 84902181691 scopus 로고    scopus 로고
    • WHO issues guidelines on HCV amid drug cost controversy
    • Slomski A. WHO issues guidelines on HCV amid drug cost controversy. JAMA. 2014;311:2262-2263.
    • (2014) JAMA , vol.311 , pp. 2262-2263
    • Slomski, A.1
  • 42
    • 84906218627 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of sofosbuvir plus peginterferon/ribavirin in the treatment of chronic hepatitis C virus genotype 1 infection
    • Saab S, Gordon SC, Park H, et al. Cost-effectiveness analysis of sofosbuvir plus peginterferon/ribavirin in the treatment of chronic hepatitis C virus genotype 1 infection. Aliment Pharmacol Ther. 2014;40(6):657-675.
    • (2014) Aliment Pharmacol Ther , vol.40 , Issue.6 , pp. 657-675
    • Saab, S.1    Gordon, S.C.2    Park, H.3
  • 43
    • 84902797741 scopus 로고    scopus 로고
    • Letter: Estimating the cost-neutral price of sofosbuvir-based triple therapy for the treatment of naïve patients with genotype 1 HCV infection in Italy
    • Messori A, Maratea D, Fadda V, Trippoli S. Letter: estimating the cost-neutral price of sofosbuvir-based triple therapy for the treatment of naïve patients with genotype 1 HCV infection in Italy. Aliment Pharmacol Ther. 2014;40(2):217-218. doi: 10.1111/apt.12823.
    • (2014) Aliment Pharmacol Ther , vol.40 , Issue.2 , pp. 217-218
    • Messori, A.1    Maratea, D.2    Fadda, V.3    Trippoli, S.4
  • 44
    • 84875028702 scopus 로고    scopus 로고
    • Rapid progression to decompensated cirrhosis, liver transplant, and death in HIV-infected men after primary hepatitis C virus infection
    • Fierer DS, Dieterich DT, Fiel MI, et al. Rapid progression to decompensated cirrhosis, liver transplant, and death in HIV-infected men after primary hepatitis C virus infection. Clin Infect Dis. 2013;56:1038-1043.
    • (2013) Clin Infect Dis , vol.56 , pp. 1038-1043
    • Fierer, D.S.1    Dieterich, D.T.2    Fiel, M.I.3
  • 45
    • 84904570994 scopus 로고    scopus 로고
    • Sofosbuvir and ribavirin for hepatitis C in patients with HIV coinfection
    • Sulkowski MS, Naggie S, Lalezari J, et al. Sofosbuvir and ribavirin for hepatitis C in patients with HIV coinfection. JAMA. 2014;312:353-361.
    • (2014) JAMA , vol.312 , pp. 353-361
    • Sulkowski, M.S.1    Naggie, S.2    Lalezari, J.3
  • 46
    • 84911409020 scopus 로고    scopus 로고
    • Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: The COSMOS randomised study
    • Lawitz E, Sulkowski MS, Ghalib R, et al. Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study. Lancet. 2014;384(9956):1756-1765.
    • (2014) Lancet , vol.384 , Issue.9956 , pp. 1756-1765
    • Lawitz, E.1    Sulkowski, M.S.2    Ghalib, R.3
  • 47
    • 84926308755 scopus 로고    scopus 로고
    • Silver Spring, MD: U.S. Food and Drug Administration; October 10 Accessed November 1, 2014
    • FDA approves first combination pill to treat hepatitis C [news release]. Silver Spring, MD: U.S. Food and Drug Administration; October 10, 2014. www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm418365.htm. Accessed November 1, 2014.
    • (2014) FDA Approves First Combination Pill to Treat Hepatitis C [News Release]
  • 48
    • 85030388218 scopus 로고    scopus 로고
    • Foster City, CA: Gilead Sciences, Inc.
    • Harvoni [product labeling]. Foster City, CA: Gilead Sciences, Inc.; 2014.
    • (2014) Harvoni [Product Labeling]
  • 50
    • 84924416356 scopus 로고    scopus 로고
    • North Chicago, IL: AbbVie Inc.
    • Viekira Pak [package insert]. North Chicago, IL: AbbVie Inc.; 2014.
    • (2014) Viekira Pak [Package Insert]


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