Simultaneous determination of propofol and its glucuronide in whole blood by liquid chromatography-electrospray tandem mass spectrometry and the influence of sample storage conditions on the reliability of the test results

Journal of Pharmaceutical and Biomedical Analysis

Volumn 109, Issue , 2015, Pages 158-163

  Sørensen, Lambert K ^a   Hasselstrøm, Jørgen B ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Blood; LC MS MS; Propofol; Propofol glucuronide; Stability

Indexed keywords

ACETONITRILE; ALFENTANIL; AMIODARONE; ATROPINE; BUPIVACAINE; CITALOPRAM; CLONAZEPAM; DIAZEPAM; DIMETHYL SULFOXIDE; EDETIC ACID; EPHEDRINE; ETIRACETAM; FENTANYL; FLUORIDE; HALOPERIDOL; IBUPROFEN; KETAMINE; LIDOCAINE; METHANOL; METOCLOPRAMIDE; MIDAZOLAM; MORPHINE; NORDAZEPAM; OXALIC ACID; PARACETAMOL; PROFOLOL BETA DEXTRO GLUCURONIDE; PROPOFOL; PROPOFOL D 17; PROPOFOL D 17 BETA DEXTRO GLUCURONIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; GLUCURONIDE; INTRAVENOUS ANESTHETIC AGENT;

ARTICLE; CONTROLLED STUDY; DILUTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG STABILITY; DRUG STORAGE; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; SOLID PHASE EXTRACTION; STORAGE TEMPERATURE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS; BLOOD; CALIBRATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LABORATORY DIAGNOSIS; SUBSTANCE ABUSE;

ANESTHETICS, INTRAVENOUS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDES; HUMANS; LIMIT OF DETECTION; PROPOFOL; REPRODUCIBILITY OF RESULTS; SPECIMEN HANDLING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

EID: 84924347698     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.02.035     Document Type: Article

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