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Volumn 111, Issue 52, 2014, Pages 18661-18666

Genetic modifiers of EGFR dependence in non-small cell lung cancer

Author keywords

Epidermal growth factor receptor; Non small cell lung cancer; ORF

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; ITK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MOS PROTEIN; MSTR1R PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; EMT PROTEIN-TYROSINE KINASE; FGFR1 PROTEIN, HUMAN; FGFR2 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE A; RAF PROTEIN; RON PROTEIN; TROPOMYOSIN-RELATED KINASE-B, HUMAN;

EID: 84924325933     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1412228112     Document Type: Article
Times cited : (43)

References (36)
  • 1
    • 0037025173 scopus 로고    scopus 로고
    • Cancer. Addiction to oncogenes - The Achilles heal of cancer
    • Weinstein IB (2002) Cancer. Addiction to oncogenes - the Achilles heal of cancer. Science 297(5578):63-64.
    • (2002) Science , vol.297 , Issue.5578 , pp. 63-64
    • Weinstein, I.B.1
  • 2
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, et al. (2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304(5676):1497-1500.
    • (2004) Science , vol.304 , Issue.5676 , pp. 1497-1500
    • Paez, J.G.1
  • 3
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, et al. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350(21):2129-2139.
    • (2004) N Engl J Med , vol.350 , Issue.21 , pp. 2129-2139
    • Lynch, T.J.1
  • 4
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, et al. (2004) EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 101(36):13306-13311.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.36 , pp. 13306-13311
    • Pao, W.1
  • 5
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, et al. (2009) Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 361(10):947-957.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1
  • 6
    • 69949186250 scopus 로고    scopus 로고
    • Screening for epidermal growth factor receptor mutations in lung cancer
    • Rosell R, et al.; Spanish Lung Cancer Group (2009) Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 361(10):958-967.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 958-967
    • Rosell, R.1
  • 7
    • 43749107912 scopus 로고    scopus 로고
    • Acquired resistance to tyrosine kinase inhibitors during cancer therapy
    • Engelman JA, Settleman J (2008) Acquired resistance to tyrosine kinase inhibitors during cancer therapy. Curr Opin Genet Dev 18(1):73-79.
    • (2008) Curr Opin Genet Dev , vol.18 , Issue.1 , pp. 73-79
    • Engelman, J.A.1    Settleman, J.2
  • 8
    • 79953046542 scopus 로고    scopus 로고
    • FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR
    • Bivona TG, et al. (2011) FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR. Nature 471(7339):523-526.
    • (2011) Nature , vol.471 , Issue.7339 , pp. 523-526
    • Bivona, T.G.1
  • 9
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, et al. (2007) MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316(5827):1039-1043.
    • (2007) Science , vol.316 , Issue.5827 , pp. 1039-1043
    • Engelman, J.A.1
  • 10
    • 84867760241 scopus 로고    scopus 로고
    • HER2 amplification: A potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation
    • Takezawa K, et al. (2012) HER2 amplification: A potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation. Cancer Discov 2(10):922-933.
    • (2012) Cancer Discov , vol.2 , Issue.10 , pp. 922-933
    • Takezawa, K.1
  • 11
    • 84864621910 scopus 로고    scopus 로고
    • Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers
    • Cheung HW, et al. (2011) Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers. Cancer Discov 1(7):608-625.
    • (2011) Cancer Discov , vol.1 , Issue.7 , pp. 608-625
    • Cheung, H.W.1
  • 12
    • 84864402225 scopus 로고    scopus 로고
    • Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
    • Zhang Z, et al. (2012) Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer. Nat Genet 44(8):852-860.
    • (2012) Nat Genet , vol.44 , Issue.8 , pp. 852-860
    • Zhang, Z.1
  • 13
    • 56249137901 scopus 로고    scopus 로고
    • HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells
    • Bachleitner-Hofmann T, et al. (2008) HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells. Mol Cancer Ther 7(11):3499-3508.
    • (2008) Mol Cancer Ther , vol.7 , Issue.11 , pp. 3499-3508
    • Bachleitner-Hofmann, T.1
  • 14
    • 84868007134 scopus 로고    scopus 로고
    • Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth
    • Harbinski F, et al. (2012) Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth. Cancer Discov 2(10):948-959.
    • (2012) Cancer Discov , vol.2 , Issue.10 , pp. 948-959
    • Harbinski, F.1
  • 15
    • 84864286442 scopus 로고    scopus 로고
    • Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
    • Wilson TR, et al. (2012) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature 487(7408):505-509.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 505-509
    • Wilson, T.R.1
  • 16
    • 35348822482 scopus 로고    scopus 로고
    • Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
    • Stommel JM, et al. (2007) Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 318(5848):287-290.
    • (2007) Science , vol.318 , Issue.5848 , pp. 287-290
    • Stommel, J.M.1
  • 17
    • 79960987021 scopus 로고    scopus 로고
    • A public genome-scale lentiviral expression library of human ORFs
    • Yang X, et al. (2011) A public genome-scale lentiviral expression library of human ORFs. Nat Methods 8(8):659-661.
    • (2011) Nat Methods , vol.8 , Issue.8 , pp. 659-661
    • Yang, X.1
  • 18
    • 78650309875 scopus 로고    scopus 로고
    • COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
    • Johannessen CM, et al. (2010) COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 468(7326):968-972.
    • (2010) Nature , vol.468 , Issue.7326 , pp. 968-972
    • Johannessen, C.M.1
  • 19
    • 77954425045 scopus 로고    scopus 로고
    • Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations
    • Yeo WL, et al. (2010) Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations. J Thorac Oncol 5(7):1048-1053.
    • (2010) J Thorac Oncol , vol.5 , Issue.7 , pp. 1048-1053
    • Yeo, W.L.1
  • 20
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi S, et al. (2005) EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 352(8):786-792.
    • (2005) N Engl J Med , vol.352 , Issue.8 , pp. 786-792
    • Kobayashi, S.1
  • 21
    • 33847323129 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in lung cancer
    • Sharma SV, Bell DW, Settleman J, Haber DA (2007) Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 7(3):169-181.
    • (2007) Nat Rev Cancer , vol.7 , Issue.3 , pp. 169-181
    • Sharma, S.V.1    Bell, D.W.2    Settleman, J.3    Haber, D.A.4
  • 22
    • 67651006061 scopus 로고    scopus 로고
    • Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
    • Sos ML, et al. (2009) Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 119(6):1727-1740.
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1727-1740
    • Sos, M.L.1
  • 23
    • 36949007159 scopus 로고    scopus 로고
    • Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha
    • Lu Y, Liang K, Li X, Fan Z (2007) Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha. Mol Cancer 6:63.
    • (2007) Mol Cancer , vol.6 , pp. 63
    • Lu, Y.1    Liang, K.2    Li, X.3    Fan, Z.4
  • 24
    • 77949685981 scopus 로고    scopus 로고
    • RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
    • Hatzivassiliou G, et al. (2010) RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature 464(7287):431-435.
    • (2010) Nature , vol.464 , Issue.7287 , pp. 431-435
    • Hatzivassiliou, G.1
  • 25
    • 0033583220 scopus 로고    scopus 로고
    • c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
    • Biscardi JS, et al. (1999) c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem 274(12):8335-8343.
    • (1999) J Biol Chem , vol.274 , Issue.12 , pp. 8335-8343
    • Biscardi, J.S.1
  • 26
    • 73349129405 scopus 로고    scopus 로고
    • Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition
    • Faber AC, et al. (2009) Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition. Proc Natl Acad Sci USA 106(46):19503-19508.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.46 , pp. 19503-19508
    • Faber, A.C.1
  • 27
    • 4544235743 scopus 로고    scopus 로고
    • c-Src and cooperating partners in human cancer
    • Ishizawar R, Parsons SJ (2004) c-Src and cooperating partners in human cancer. Cancer Cell 6(3):209-214.
    • (2004) Cancer Cell , vol.6 , Issue.3 , pp. 209-214
    • Ishizawar, R.1    Parsons, S.J.2
  • 28
    • 84872562509 scopus 로고    scopus 로고
    • c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met
    • Stabile LP, et al. (2013) c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met. Clin Cancer Res 19(2):380-392.
    • (2013) Clin Cancer Res , vol.19 , Issue.2 , pp. 380-392
    • Stabile, L.P.1
  • 29
    • 34548546535 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab
    • Lu Y, et al. (2007) Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab. Cancer Res 67(17):8240-8247.
    • (2007) Cancer Res , vol.67 , Issue.17 , pp. 8240-8247
    • Lu, Y.1
  • 30
    • 66149083997 scopus 로고    scopus 로고
    • Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab
    • Wheeler DL, et al. (2009) Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab. Cancer Biol Ther 8(8):696-703.
    • (2009) Cancer Biol Ther , vol.8 , Issue.8 , pp. 696-703
    • Wheeler, D.L.1
  • 31
    • 84903767202 scopus 로고    scopus 로고
    • CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance
    • Park KS, et al. (2014) CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance. J Clin Invest 124(7):3003-3015.
    • (2014) J Clin Invest , vol.124 , Issue.7 , pp. 3003-3015
    • Park, K.S.1
  • 32
    • 84886002801 scopus 로고    scopus 로고
    • Erlotinib resistance in lung cancer cells mediated by integrinbeta1/Src/Akt-driven bypass signaling
    • Kanda R, et al. (2013) Erlotinib resistance in lung cancer cells mediated by integrinbeta1/Src/Akt-driven bypass signaling. Cancer Res 73(20):6243-6253.
    • (2013) Cancer Res , vol.73 , Issue.20 , pp. 6243-6253
    • Kanda, R.1
  • 33
    • 84880525684 scopus 로고    scopus 로고
    • A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop
    • Ware KE, et al. (2013) A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop. Oncogenesis 2:e39.
    • (2013) Oncogenesis , vol.2 , pp. e39
    • Ware, K.E.1
  • 34
    • 84880547779 scopus 로고    scopus 로고
    • Activation of the FGF2-FGFR1 autocrine pathway: A novel mechanism of acquired resistance to gefitinib in NSCLC
    • Terai H, et al. (2013) Activation of the FGF2-FGFR1 autocrine pathway: A novel mechanism of acquired resistance to gefitinib in NSCLC. Mol Cancer Res 11(7):759-767.
    • (2013) Mol Cancer Res , vol.11 , Issue.7 , pp. 759-767
    • Terai, H.1
  • 35
    • 79955675804 scopus 로고    scopus 로고
    • Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression
    • Ware KE, et al. (2010) Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression. PLoS ONE 5(11):e14117.
    • (2010) PLoS ONE , vol.5 , Issue.11 , pp. e14117
    • Ware, K.E.1
  • 36
    • 79953118839 scopus 로고    scopus 로고
    • Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
    • Sequist LV, et al. (2011) Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 3(75):75ra26.
    • (2011) Sci Transl Med , vol.3 , Issue.75 , pp. 75ra26
    • Sequist, L.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.