Development and validation of a RP-HPLC method for the simultaneous determination of Mangiferin, Ellagic acid and Hydroxycitric acid in polyherbal formulation

Pharmacognosy Journal

Volumn 6, Issue 3, 2014, Pages 23-28

  Kammalla, Ananth Kumar ^a   Ramasamy, Mohan Kumar ^a   Agarwal, Aruna ^b   Dubey, G P ^b   Ilango, Kaliappan ^a  

^a SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Ellagic acid; Hydroxycitric acid; Mangiferin; Polyherbal formulation; RP HPLC

Indexed keywords

ELLAGIC ACID; HYDROXYCITRIC ACID; MANGIFERIN;

ARTICLE; CORRELATION COEFFICIENT; DRUG DETERMINATION; DRUG FORMULATION; FRUIT; GARCINIA; GARCINIA INDICA; LAGESTROEMIA PARVIFLORA; LYTHRACEAE; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; PLANT ROOT; QUALITY CONTROL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SALACIA;

EID: 84924295994     PISSN: 09753575     EISSN: 09753575     Source Type: Journal    
DOI: 10.5530/pj.2014.3.4     Document Type: Article

References (16)

1. Conte AA. The effects of (-)-hydroxycitrate and chromium (GTF) on obesity. Journal of American College of Nutrition. 1994;13: 535-536.
2. Dandan Han, Chen Chengjun, Zhang Cong, Zhang Yu and Tang Xing. Determination of mangiferin in rat plasma by liquid-liquid extraction with UPLC-MS/MS. Journal of pharmaceutical and biomedical analysis. 2010;51:260-263.
3. Dhalwal K, Biradar YS and Rajani M. High-performance thin-layer chromatography densitometric method for simultaneous quantitation of phyllantin, hypophyllanthin, gallic acid and ellagic acid in Phyllanthus amarus. Journal of AOAC international. 2006;89:619-623.
4. Dubey Govind Prasad, Aruna Agrawal, Nirupama Dubey, Shipra Dubey, R Dubey, and SM Deborah. Herbal formualtion for the prevention and management of Type-2 Diabetes mellitus and vascular complications associated with diabetes. Ed. SRM University. USA Patent 8337911B2. Dec 25, 2013.
5. Hayashi T, et al. Ellagitannins from Lagestroemia speciosa as activators of glucose trasport in fat cells.Planta Medica. 2002;68:173-175.
6. Igho Onakpoya, Hung Kang Shao, Perry Rachel, Wider Barbara and Ernst Edzard. The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss supplement: A systematic Review and Meta-Analysis of Randomised Clinical Trials.Journal of Obesity 2011;1-9.
7. Ilango Kaliappan, Kammalla Kumar Ananth, Ramasamy Mohan Kumar, Agarwal Aruna, and GP Dubey. Emerging need of pharmacokinetics in Ayurvedic system of medicine. International Journal of Research in Ayurveda and Pharmacy, 2013;4:647-651.
8. International Conference on Harmonization. Guideline on Validation of Analytical Procedure-Methodology. Geneva, 1996.
9. Jayaprakasha GK, Sakariah KK. Determination of organic acids in leaves and rinds of Garcinia indica (Desr.) by LC. Journal of Pharmaceutical and Biomedical Analysis. 2002; 28:379-384.
10. Jayaprakasha GK, Sakariah KK. Determination of (-) Hydroxycitric acid in commerical samples of Garcinia cambogia extract by liquid chromatography with ultraviolet detection. Journal of Liquid chromatography and relative technology. 2000;23:915-923.
11. Khanduja KL, Gandhi RK, Pathania V and Shal N. Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice. Food and Chemical Toxicology. 1999;37:313-318.
12. Ong ES. Extraction methods and chemical standardization of botanical and herbal preparations. Journal of Chromatography B. 2004;812:23-33.
13. Ronghua Dai, Gao Jun and Bi Kaishun. High performance liquid chromatographic method for the determination and pharmacokinetic study of mangifeirn in plasma of rats of rats having taken the traditional chinese medicinal preparation Zi- Shen Pill. Journal of Chromatographic science. 2004;42;88-90.
14. Vasudev SS, et al. Validated HPLC method for the simultaneous determination of taxol and ellagic acid in Punica granatum fruit extract containing combination formualtion. Pharmazie. 2012;67:834-838.
15. Yoshikawa M, Ninomiya K, Shimoda H, Nishida N, Matsuda H. Hepatoprotective and antioxidant properties of Salacia reticulate : Preventive effects of phenolic constituents on CCl4-induced injury in mice. Biological pharmaceutical bulletien. 2001;25:72-76.
16. Yoshikawa M, Nishida N, Shimoda H, Takada M, Kawahara Y, and Matsuda H. Polyphenol constituents from Salacia species: quantitative analysis of mangiferin with alpha-glucosidase and aldose reductase inhibitory activities.Yakugaku Zasshi. 2001;121:371-378.