A lipid mediator hepoxilin A3 is a natural inducer of neutrophil extracellular traps in human neutrophils

Mediators of Inflammation

Volumn 2015, Issue , 2015, Pages

  Douda, David N ^a,b,c   Grasemann, Hartmut ^a,b,d   Pace Asciak, Cecil ^a,e   Palaniyar, Nades ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEPOXILIN A; HEPOXILIN B; LIPID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; 10-HYDROXY-11,12-EPOXYEICOSA-5,8,14-TRIENOIC ACID; 8-HYDROXY-11,12-EPOXYEICOSA-5,9,14-TRIENOIC ACID; DIHOMO GAMMA LINOLENIC ACID;

ARTICLE; CELL ACTIVATION; CYSTIC FIBROSIS; EXTRACELLULAR TRAP; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; NEUTROPHIL; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; METABOLISM;

8,11,14-EICOSATRIENOIC ACID; CELLS, CULTURED; CYSTIC FIBROSIS; EXTRACELLULAR TRAPS; HUMANS; NEUTROPHILS;

EID: 84924278958     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2015/520871     Document Type: Article

References (28)

1. A. Mócsai, "Diverse novel functions of neutrophils in immunity, inflammation, and beyond," The Journal of Experimental Medicine, vol. 210, no. 7, pp. 1283-1299, 2013.
2. V. Brinkmann and A. Zychlinsky, "Neutrophil extracellular traps: is immunity the second function of chromatin?"TheJournal of Cell Biology, vol. 198, no. 5, pp. 773-783, 2012.
3. V. Brinkmann, U. Reichard, C. Goosmann et al., "Neutrophil extracellular traps kill bacteria," Science, vol. 303, no. 5663, pp. 1532-1535, 2004.
4. O. Z. Cheng and N. Palaniyar, "NET balancing: a problem in inflammatory lung diseases," Frontiers in Immunology, vol. 4, article 1, 2013.
5. M. Saffarzadeh, C. Juenemann, M. A. Queisser et al., "Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones," PLoS ONE, vol. 7, no. 2, Article ID e32366, 2012.
6. A. Caudrillier, K. Kessenbrock, B. M. Gilliss et al., "Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury,"The Journal of Clinical Investigation, vol. 122, no. 7, pp. 2661-2671, 2012.
7. G. M.Thomas, C. Carbo, B. R. Curtis et al., "ExtracellularDNA traps are associated with the pathogenesis of TRALI in humans and mice," Blood, vol. 119, no. 26, pp. 6335-6343, 2012.
8. J. Rossaint, J. M. Herter, H. van Aken et al., "Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation," Blood, vol. 123, no. 16, pp. 2573-2584, 2014.
9. N. Branzk, A. Lubojemska, S. E. Hardison et al., "Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens," Nature Immunology, vol. 15, no. 11, pp. 1017-1025, 2014.
10. T. Narasaraju, E. Yang, R. P. Samy et al., "Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis," The American Journal of Pathology, vol. 179, no. 1, pp. 199-210, 2011.
11. M. Dwyer, Q. Shan, S. D'Ortona et al., "Cystic fibrosis sputum DNA has netosis characteristics and neutrophil extracellular trap release is regulated by macrophage migration-inhibitory factor," Journal of Innate Immunity, vol. 6, no. 6, pp. 765-779, 2014.
12. C. R. Pace-Asciak and J. M. Martin, "Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets," Prostaglandins, Leukotrienes and Medicine, vol. 16, no. 2, pp. 173-180, 1984.
13. C. R. Pace-Asciak, "The hepoxilins and some analogues: a review of their biology," British Journal of Pharmacology, vol. 158, no. 4, pp. 972-981, 2009.
14. B. P. Hurley, D. Siccardi, R. J. Mrsny, and B. A. McCormick, "Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3," The Journal of Immunology, vol. 173, no. 9, pp. 5712-5720, 2004.
15. B. A.McCormick, "Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator," The FEBS Journal, vol. 274, no. 14, pp. 3513-3518, 2007.
16. S. Dho, S.Grinstein, E. J.Corey,W.-G. Su, andC.R. Pace-Asciak, "Hepoxilin A3 induces changes in cytosolic calcium, intracellular pH and membrane potential in human neutrophils," Biochemical Journal, vol. 266, no. 1, pp. 63-68, 1990.
17. H. Berkefeld, B. Fakler, and U. Schulte, "Ca2+-activated K+ channels: from protein complexes to function," Physiological Reviews, vol. 90, no. 4, pp. 1437-1459, 2010.
18. E. J. Corey and W. G. Su, "Total synthesis of biologically active metabolites of arachidonic acid. The two 8-hydroxy-11,12(S,S)-epoxyeicosa-5,14(Z), 9(E)-trienoic acids," Tetrahedron Letters, vol. 25, no. 45, pp. 5119-5122, 1984.
19. P. M. Demin and C. R. Pace-Asciak, "Synthesis of racemic 11,12-cyclopropyl analogs of hepoxilins A3 and B3," Tetrahedron Letters, vol. 34, no. 27, pp. 4305-4308, 1993.
20. F. H. Pilsczek, D. Salina, K. K. H. Poon et al., "A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus," The Journal of Immunology, vol. 185, no. 12, pp. 7413-7425, 2010.
21. E. Villanueva, S. Yalavarthi, C. C. Berthier et al., "Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus," Journal of Immunology, vol. 187, no. 1, pp. 538-552, 2011.
22. D. Reynaud, P. M. Demin, M. Sutherland, S. Nigam, and C. R. Pace-Asciak, "Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3," FEBS Letters, vol. 446, no. 2-3, pp. 236-238, 1999.
23. S. Nigam, S. Nodes, G. Cichon, E. J. Corey, and C. R. Pace-Asciak, "Receptor-mediated action of hepoxilin A3 releases diacylglycerol and arachidonic acid fromhuman neutrophils," Biochemical and Biophysical Research Communications, vol. 171, no. 3, pp. 944-948, 1990.
24. H. Parker, M. Dragunow, M. B. Hampton, A. J. Kettle, and C. C. Winterbourn, "Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus," Journal of Leukocyte Biology, vol. 92, no. 4, pp. 841-849, 2012.
25. Q. M. Parks, R. L. Young, K. R. Poch, K. C. Malcolm, M. L. Vasil, and J. A.Nick, "Neutrophil enhancement of Pseudomonas aeruginosa biofilm development: human F-actin and DNA as targets for therapy," Journal ofMedicalMicrobiology, vol. 58,part 4, pp. 492-502, 2009.
26. T. S.Walker, K. L. Tomlin, G. S.Worthen et al., "Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils," Infection and Immunity, vol. 73, no. 6, pp. 3693-3701, 2005.
27. R. B. Thornton, S. P. Wiertsema, L.-A. S. Kirkham et al., "Neutrophil extracellular traps and bacterial biofilms in middle ear effusion of children with recurrent acute otitismedia-a potential treatment target," PLoS ONE, vol. 8, no. 2,Article IDe53837, 2013.
28. D. L. Tamang,W. Pirzai, G. P. Priebe et al., "Hepoxilin A3 facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers," Journal of Immunology, vol. 189, no. 10, pp. 4960-4969, 2012.