Biomarkers of Coronary Artery Disease Differ Between Asians and Caucasians in the General Population

Global Heart

Volumn 10, Issue 4, 2015, Pages 301-311.e11

  Gijsberts, Crystel M ^a,b   den Ruijter, Hester M ^a   Asselbergs, Folkert W ^a,b,c   Chan, Mark Y ^d,e   de Kleijn, Dominique P V ^a,d,e   Hoefer, Imo E ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e DEPARTMENT OF CARDIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; FIBRINOGEN; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRIACYLGLYCEROL; BLOOD CLOTTING FACTOR; GLUCOSE BLOOD LEVEL;

ASIAN; BLOOD CLOTTING; CAUCASIAN; CHINESE; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; CORONARY ARTERY DISEASE; CORONARY RISK; ETHNIC DIFFERENCE; ETHNIC GROUP; ETHNICITY; FIBRINOGEN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HEMOGLOBIN BLOOD LEVEL; HUMAN; INCIDENCE; INSULIN BLOOD LEVEL; JAPANESE (PEOPLE); LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; PREDICTIVE VALUE; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; REVIEW; SYSTEMATIC REVIEW; TRIACYLGLYCEROL BLOOD LEVEL; ASIA; ASIAN CONTINENTAL ANCESTRY GROUP; ETHNOLOGY; EUROPE; FEMALE; MALE; META ANALYSIS; METABOLISM; MIGRATION;

ASIA, WESTERN; ASIAN CONTINENTAL ANCESTRY GROUP; BIOMARKERS; BLOOD COAGULATION FACTORS; BLOOD GLUCOSE; C-REACTIVE PROTEIN; COHORT STUDIES; CORONARY ARTERY DISEASE; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; LIPID METABOLISM; MALE; PREVALENCE; TRANSIENTS AND MIGRANTS;

EID: 84924143281     PISSN: 22118160     EISSN: 22118179     Source Type: Journal    
DOI: 10.1016/j.gheart.2014.11.004     Document Type: Review

References (73)

1. 1 Ford, E.S., Ajani, U.A., Croft, J.B., et al. Explaining the decrease in U.S. deaths from coronary disease, 1980–2000. N Engl J Med 356 (2007), 2388–2398.
2. 2 Mathers, C.D., Loncar, D., Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med, 3, 2006, e442.
3. 3 Kannel, W.B., McGee, D., Gordon, T., A general cardiovascular risk profile: the Framingham Study. Am J Cardiol 38 (1976), 46–51.
4. 4 Anand, S.S., Yusuf, S., Vuksan, V., et al. Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE). Lancet 356 (2000), 279–284.
5. 5 Zheng, Y., Ma, W., Zeng, Y., et al. Comparative study of clinical characteristics between Chinese Han and German Caucasian patients with coronary heart disease. Clin Res Cardiol 99 (2010), 45–50.
6. 6 Joshi, P., Islam, S., Pais, P., et al. Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA 297 (2007), 286–294.
7. 7 Goff, D.C., Lloyd-Jones, D.M., Bennett, G., et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129 (2014), S49–73.
8. 8 Tillin, T., Hughes, A.D., Whincup, P., et al., for the SABRE Study Group. Ethnicity and prediction of cardiovascular disease: performance of QRISK2 and Framingham scores in a U.K. tri-ethnic prospective cohort study (SABRE–Southall And Brent REvisited). Heart 100 (2014), 60–67.
9. 9 Kandula, N.R., Diez-Roux, A.V., Chan, C., et al. Association of acculturation levels and prevalence of diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care 31 (2008), 1621–1628.
10. 10 Diez Roux, A.V., Detrano, R., Jackson, S., et al. Acculturation and socioeconomic position as predictors of coronary calcification in a multiethnic sample. Circulation 112 (2005), 1557–1565.
11. 11 Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., the PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med, 6, 2009, e1000097.
12. 12 Cappuccio, F.P., Bell, R., Perry, I.J., et al. Homocysteine levels in men and women of different ethnic and cultural background living in England. Atherosclerosis 164 (2002), 95–102.
13. 13 Siezenga, M.A., Chandie Shaw, P.K., van der Geest, R.N., et al. Enhanced complement activation is part of the unfavourable cardiovascular risk profile in South Asians. Clin Exp Immunol 157 (2009), 98–103.
14. 14 Shamaei-Tousi, A., Stephens, J.W., Bin, R., et al. Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus. Eur Heart J 27 (2006), 1565–1570.
15. 15 Adler, A.I., Neil, H.A.W., Stratton, I.M., Holman, R.R., Turner, R.C., Ethnicity and cardiovascular disease: the incidence of myocardial infarction in white, South Asian, and Afro-Caribbean patients with type 2 diabetes (U.K. Prospective Diabetes Study 32). Diabetes Care 21 (1998), 1271–1277.
16. 16 Ajjan, R., Carter, A., Somani, R., Ethnic differences in cardiovascular risk factors in healthy Caucasian and South Asian individuals with the metabolic syndrome. J Thromb Haemost 5 (2007), 754–760.
17. 17 Kain, K., Blaxill, J.M., Catto, A.J., Grant, P.J., Carter, A.M., Increased fibrinogen levels among South Asians versus Whites in the United Kingdom are not explained by common polymorphisms. Am J Epidemiol 156 (2002), 174–179.
18. 18 Anand, S.S., Razak, F., Yi, Q., et al. C-reactive protein as a screening test for cardiovascular risk in a multiethnic population. Arterioscler Thromb Vasc Biol 24 (2004), 1509–1515.
19. 19 Bathula, R., Hughes, A.D., Panerai, R., et al. Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease. Diabetologia 53 (2010), 2120–2128.
20. 20 Bellary, S., O'Hare, J.P., Raymond, N.T., et al. Premature cardiovascular events and mortality in south Asians with type 2 diabetes in the United Kingdom Asian Diabetes Study - effect of ethnicity on risk. Curr Med Res Opin 26 (2010), 1873–1879.
21. 21 Bhalodkar, N.C., Blum, S., Rana, T., et al. Comparison of levels of large and small high-density lipoprotein cholesterol in Asian Indian men compared with Caucasian men in the Framingham Offspring Study. Am J Cardiol 94 (2004), 1561–1563.
22. 22 Bhopal, R., Fischbacher, C., Vartiainen, E., Unwin, N., White, M., Alberti, G., Predicted and observed cardiovascular disease in South Asians: application of FINRISK, Framingham and SCORE models to Newcastle Heart Project data. J Public Health (Oxf) 27 (2005), 93–100.
23. 23 Reynolds, R.M., Fischbacher, C., Bhopal, R., et al. Differences in cortisol concentrations in South Asian and European men living in the United Kingdom. Clin Endocrinol (Oxf) 64 (2006), 530–534.
24. 24 Cappuccio, F.P., Oakeshott, P., Strazzullo, P., Kerry, S.M., Application of Framingham risk estimates to ethnic minorities in United Kingdom and implications for primary prevention of heart disease in general practice: cross sectional population based study. BMJ, 325, 2002, 1271.
25. 25 Cook, D.G., Cappuccio, F.P., Atkinson, R.W., et al. Ethnic differences in fibrinogen levels: the role of environmental factors and the beta-fibrinogen gene. Am J Epidemiol 153 (2001), 799–806.
26. 26 Miller, M.A., Sagnella, G.A., Kerry, S.M., Strazzullo, P., Cook, D.G., Cappuccio, F.P., Ethnic differences in circulating soluble adhesion molecules: the Wandsworth Heart and Stroke Study. Clin Sci (Lond) 104 (2003), 591–598.
27. 27 Miller, M.A., McTernan, P.G., Harte, A.L., et al. Ethnic and sex differences in circulating endotoxin levels: a novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population. Atherosclerosis 203 (2009), 494–502.
28. 28 Chambers, J.C., McGregor, A., Jean-Marie, J., Kooner, J.S., Abnormalities of vascular endothelial function may contribute to increased coronary heart disease risk in UK Indian Asians. Heart 81 (1999), 501–504.
29. 29 Chambers, J.C., Eda, S., Bassett, P., et al. C-reactive protein, insulin resistance, central obesity, and coronary heart disease risk in Indian Asians from the United Kingdom compared with European whites. Circulation 104 (2001), 145–150.
30. 30 Chandalia, M., Cabo-Chan, A.V. Jr., Devaraj, S., Jialal, I., Grundy, S.M., Abate, N., Elevated plasma high-sensitivity C-reactive protein concentrations in Asian Indians living in the United States. J Clin Endocrinol Metab 88 (2003), 3773–3776.
31. 31 Chowdhury, T.A., Lasker, S.S., Complications and cardiovascular risk factors in South Asians and Europeans with early-onset type 2 diabetes. QJM 95 (2002), 241–246.
32. 32 Chowdhury, T.A., Lasker, S.S., Mahfuz, R., Ethnic differences in control of cardiovascular risk factors in patients with type 2 diabetes attending an Inner London diabetes clinic. Postgrad Med J 82 (2006), 211–215.
33. 33 Forouhi, N.G., Sattar, N., Tillin, T., McKeigue, P.M., Chaturvedi, N., Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK. Diabetologia 49 (2006), 2580–2588.
34. 34 Gama, R., Elfatih, A.B., Anderson, N.R., Ethnic differences in total and HDL cholesterol concentrations: Caucasians compared with predominantly Punjabi Sikh Indo-Asians. Ann Clin Biochem 39 (2002), 609–611.
35. 35 Chatha, K., Anderson, N.R., Gama, R., Ethnic variation in C-reactive protein: UK resident Indo-Asians compared with Caucasians. J Cardiovasc Risk 9 (2002), 139–141.
36. 36 Heald, A.H., Anderson, S.G., Ivison, F., Laing, I., Gibson, J.M., Cruickshank, K., C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis 170 (2003), 79–86.
37. 37 Iso, H., Koike, K.A., Folsom, A.R., et al. Lipoprotein(a) and its correlates in Japanese and U.S. population samples. Ann Epidemiol 6 (1996), 324–330.
38. 38 Kamath, S.K., Hussain, E.A., Amin, D., et al. Cardiovascular disease risk factors in 2 distinct ethnic groups: Indian and Pakistani compared with American premenopausal women. Am J Clin Nutr 69 (1999), 621–631.
39. 39 Kanaya, A.M., Kandula, N.R., Ewing, S.K., et al. Comparing coronary artery calcium among U.S. South Asians with four racial/ethnic groups: the MASALA and MESA studies. Atherosclerosis 234 (2014), 102–107.
40. 40 Bild, D.E., Detrano, R., Peterson, D., et al. Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation 111 (2005), 1313–1320.
41. 41 Veeranna, V., Zalawadiya, S.K., Niraj, A., Kumar, A., Ference, B., Afonso, L., Association of novel biomarkers with future cardiovascular events is influenced by ethnicity: results from a multi-ethnic cohort. Int J Cardiol 166 (2013), 487–493.
42. 42 Kelley-Hedgepeth, A., Lloyd-Jones, D.M., Colvin, A., et al., for the SWAN Investigators. Ethnic differences in C-reactive protein concentrations. Clin Chem 54 (2008), 1027–1037.
43. 43 Matthews, K.A., Sowers, M.F., Derby, C.A., et al. Ethnic differences in cardiovascular risk factor burden among middle-aged women: Study of Women's Health Across the Nation (SWAN). Am Heart J 149 (2005), 1066–1073.
44. 44 Liew, C.F., Seah, E.S., Yeo, K.P., Lee, K.O., Wise, S.D., Lean, nondiabetic Asian Indians have decreased insulin sensitivity and insulin clearance, and raised leptin compared to Caucasians and Chinese subjects. Int J Obes Relat Metab Disord 27 (2003), 784–789.
45. 45 Lyratzopoulos, G., McElduff, P., Heller, R.F., Hanily, M., Lewis, P.S., Comparative levels and time trends in blood pressure, total cholesterol, body mass index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme. BMC Public Health, 5, 2005, 125.
46. 46 Miller, G.J., Kotecha, S., Wilkinson, W.H., et al. Dietary and other characteristics relevant for coronary heart disease in men of Indian, West Indian and European descent in London. Atherosclerosis 70 (1988), 63–72.
47. 47 Mulukutla, S.R., Venkitachalam, L., Marroquin, O.C., et al. Population variations in atherogenic dyslipidemia: a report from the HeartSCORE and IndiaSCORE Studies. J Clin Lipidol 2 (2008), 410–417.
48. 48 Nagi, D.K., Knowler, W.C., Hanson, R.L., Ali, V.M., Yudkin, J.S., Plasminogen activator inhibitor (PAI-1) and non-insulin-dependent diabetes in Pima Indians, south Asians and Europeans: populations at varying risk of NIDDM and coronary artery disease. Thromb Haemost 75 (1996), 921–927.
49. 49 Okamura, T., Sekikawa, A., Sawamura, T., et al., for the JUMP Study Group. LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men. Atherosclerosis 229 (2013), 240–245.
50. 50 Sekikawa, A., Ueshima, H., Kadowaki, T., et al. Less subclinical atherosclerosis in Japanese men in Japan than in White men in the United States in the post-World War II birth cohort. Am J Epidemiol 165 (2007), 617–624.
51. 51 Patel, R.T., Lev, E.I., Vaduganathan, M., et al. Platelet reactivity among Asian Indians and Caucasians. Platelets 18 (2007), 261–265.
52. 52 Raji, A., Seely, E.W., Arky, R.A., Simonson, D.C., Body fat distribution and insulin resistance in healthy Asian Indians and Caucasians. J Clin Endocrinol Metab 86 (2001), 5366–5371.
53. 53 Raji, A., Gerhard-Herman, M.D., Warren, M., et al. Insulin resistance and vascular dysfunction in nondiabetic Asian Indians. J Clin Endocrinol Metab 89 (2004), 3965–3972.
54. 54 Rapeport, N., Schamroth, C.L., Blom, D.J., Gender and ethnic differences in the control of hyperlipidaemia and other vascular risk factors: insights from the CEntralised Pan-South African survey on tHE Under-treatment of hypercholeSterolaemia (CEPHEUS SA) study. Cardiovasc J Afr 24 (2013), 238–242.
55. 55 Smith, J., Cianflone, K., Al-Amri, M., Sniderman, A., Body composition and the apoB/apoA-I ratio in migrant Asian Indians and white Caucasians in Canada. Clin Sci (Lond) 111 (2006), 201–207.
56. 56 Zhang, W., Evans, A.E., Cambien, F., et al. Distribution of lipid variables in subjects in Belfast, Northern Ireland and Taiyuan, P R China. Atherosclerosis 102 (1993), 175–180.
57. 57 Zoratti, R., Godsland, I.F., Chaturvedi, N., et al. Relation of plasma lipids to insulin resistance, nonesterified fatty acid levels, and body fat in men from three ethnic groups: relevance to variation in risk of diabetes and coronary disease. Metabolism 49 (2000), 245–252.
58. 58 Egusa, G., Watanabe, H., Ohshita, K., et al. Influence of the extent of westernization of lifestyle on the progression of preclinical atherosclerosis in Japanese subjects. J Atheroscler Thromb 9 (2002), 299–304.
59. 59 Lamarche, B., Lemieux, I., Després, J.P., The small, dense LDL phenotype and the risk of coronary heart disease: epidemiology, patho-physiology and therapeutic aspects. Diabetes Metab 25 (1999), 199–211.
60. 60 Raschke, V., Elmadfa, I., Bermingham, M.A., Steinbeck, K., Low density lipoprotein subclasses in Asian and Caucasian adolescent boys. Asia Pac J Clin Nutr 15 (2006), 496–501.
61. 61 McKeigue, P.M., Coronary heart disease in Indians, Pakistanis, and Bangladeshis: aetiology and possibilities for prevention. Br Heart J 67 (1992), 341–342.
62. 62 Yusuf, S., Hawken, S., Ounpuu, S., et al., for the INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 364 (2004), 937–952.
63. 63 Kain, K., Catto, A.J., Grant, P.J., Clustering of thrombotic factors with insulin resistance in South Asian patients with ischaemic stroke. Thromb Haemost 88 (2002), 950–953.
64. 64 Kain, K., Catto, A.J., Young, J., Bamford, J., Bavington, J., Grant, P.J., Increased fibrinogen, von Willebrand factor and tissue plasminogen activator levels in insulin resistant South Asian patients with ischaemic stroke. Atherosclerosis 163 (2002), 371–376.
65. 65 Wensley, F., Gao, P., Burgess, S., et al., for the C Reactive Protein Coronary Heart Disease Genetics Collaboration. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ, 342, 2011, d548.
66. 66 Ridker, P.M., Glynn, R.J., Hennekens, C.H., C-Reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation 97 (1998), 2007–2011.
67. 67 Tracy, R.P., Lemaitre, R.N., Psaty, B.M., et al. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly: results from the Cardiovascular Health Study and the Rural Health Promotion Project. Arterioscler Thromb Vasc Biol 17 (1997), 1121–1127.
68. 68 Woodward, M., Huxley, H., Lam, T.H., et al., for the Asia Pacific Cohort Studies Collaboration. A comparison of the associations between risk factors and cardiovascular disease in Asia and Australasia. Eur J Cardiovasc Prev Rehabil 12 (2005), 484–491.
69. 69 Stampfer, M.J., Sacks, F.M., Salvini, S., Willett, W.C., Hennekens, C.H., A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N Engl J Med 325 (1991), 373–381.
70. 70 Huxley, R.R., Barzi, F., Lam, T.H., et al., for the Asia Pacific Cohort Studies Collaboration and the Obesity in Asia Collaboration. Isolated low levels of high-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease: an individual participant data meta-analysis of 23 studies in the Asia-Pacific region. Circulation 124 (2011), 2056–2064.
71. 71 Danesh, J., Lewington, S., Thompson, S.G., et al., for the Fibrinogen Studies Collaboration. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA 294 (2005), 1799–1809.
72. 72 Bhopal, R., Unwin, N., White, M., et al. Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Bangladeshi, and European origin populations: cross sectional study. BMJ, 1999, 215–220.
73. 73 D'Agostino, R.B. Sr., Vasan, R.S., Pencina, M.J., et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 117 (2008), 743–753.