메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages 33-40

Fetal asphyctic preconditioning protects against perinatal asphyxia- induced apoptosis and astrogliosis in neonatal brain

Author keywords

Apoptosis; Astrogliosis; Fetal preconditioning; Hypoxia ischemia; Neonatal brain; Perinatal asphyxia

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN;

EID: 84924135300     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527314666150116112032     Document Type: Article
Times cited : (11)

References (49)
  • 1
    • 4243059572 scopus 로고    scopus 로고
    • Determining the contribution of asphyxia to brain damage in the neonate
    • Low JA. Determining the contribution of asphyxia to brain damage in the neonate. J Obstet Gynaecol Res 2004; 30(4): 276-86.
    • (2004) J Obstet Gynaecol Res , vol.30 , Issue.4 , pp. 276-286
    • Low, J.A.1
  • 2
    • 3242704354 scopus 로고    scopus 로고
    • Reflections on the occurrence and significance of antepartum fetal asphyxia
    • Low JA. Reflections on the occurrence and significance of antepartum fetal asphyxia. Best Pract Res Clin Obstet Gynaecol 2004; 18(3): 375-82.
    • (2004) Best Pract Res Clin Obstet Gynaecol , vol.18 , Issue.3 , pp. 375-382
    • Low, J.A.1
  • 3
    • 3843064781 scopus 로고    scopus 로고
    • Why are 4 million newborn babies dying each year?
    • Lawn JE, Cousens S, Bhutta ZA, et al. Why are 4 million newborn babies dying each year? Lancet 2004; 364(9432): 399-401.
    • (2004) Lancet , vol.364 , Issue.9432 , pp. 399-401
    • Lawn, J.E.1    Cousens, S.2    Bhutta, Z.A.3
  • 4
    • 24044548649 scopus 로고    scopus 로고
    • Neuropsychological and educational problems at school age associated with neonatal encephalopathy
    • Marlow N, Rose AS, Rands CE, Draper ES. Neuropsychological and educational problems at school age associated with neonatal encephalopathy. Arch Dis Child Fetal Neonatal Ed 2005; 90(5): F380-7.
    • (2005) Arch Dis Child Fetal Neonatal Ed , vol.90 , Issue.5 , pp. F380-F387
    • Marlow, N.1    Rose, A.S.2    Rands, C.E.3    Draper, E.S.4
  • 6
    • 63849103066 scopus 로고    scopus 로고
    • Effects of therapeutic hypothermia on multiorgan dysfunction in asphyxiated newborns: Whole-body cooling versus selective head cooling
    • Sarkar S, Barks JD, Bhagat I, Donn SM. Effects of therapeutic hypothermia on multiorgan dysfunction in asphyxiated newborns: whole-body cooling versus selective head cooling. Am J Perinatol 2009; 26(4): 265-70.
    • (2009) Am J Perinatol , vol.26 , Issue.4 , pp. 265-270
    • Sarkar, S.1    Barks, J.D.2    Bhagat, I.3    Donn, S.M.4
  • 7
    • 26444452073 scopus 로고    scopus 로고
    • Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    • Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005; 353(15): 1574-84.
    • (2005) N Engl J Med , vol.353 , Issue.15 , pp. 1574-1584
    • Shankaran, S.1    Laptook, A.R.2    Ehrenkranz, R.A.3
  • 8
    • 54049103227 scopus 로고    scopus 로고
    • Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy
    • Shankaran S, Pappas A, Laptook AR, et al. Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy. Pediatrics 2008; 122(4): e791-8.
    • (2008) Pediatrics , vol.122 , Issue.4 , pp. e791-e798
    • Shankaran, S.1    Pappas, A.2    Laptook, A.R.3
  • 9
    • 13844321255 scopus 로고    scopus 로고
    • Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: Multicentre randomised trial
    • Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 2005; 365(9460): 663-70.
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 663-670
    • Gluckman, P.D.1    Wyatt, J.S.2    Azzopardi, D.3
  • 10
    • 0034071863 scopus 로고    scopus 로고
    • Cerebral hypothermia for prevention of brain injury following perinatal asphyxia
    • Gunn AJ. Cerebral hypothermia for prevention of brain injury following perinatal asphyxia. Curr Opin Pediatr 2000; 12(2): 111-5.
    • (2000) Curr Opin Pediatr , vol.12 , Issue.2 , pp. 111-115
    • Gunn, A.J.1
  • 11
    • 34548400798 scopus 로고    scopus 로고
    • Head cooling for neonatal encephalopathy: The state of the art
    • Gunn AJ, Gluckman PD. Head cooling for neonatal encephalopathy: the state of the art. Clin Obstet Gynecol 2007; 50(3): 636-51.
    • (2007) Clin Obstet Gynecol , vol.50 , Issue.3 , pp. 636-651
    • Gunn, A.J.1    Gluckman, P.D.2
  • 12
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986; 74(5): 1124-36.
    • (1986) Circulation , vol.74 , Issue.5 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 13
    • 0028221633 scopus 로고
    • Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat
    • Gidday JM, Fitzgibbons JC, Shah AR, Park TS. Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat. Neurosci Lett 1994; 168(1-2): 221-4.
    • (1994) Neurosci Lett , vol.168 , Issue.1-2 , pp. 221-224
    • Gidday, J.M.1    Fitzgibbons, J.C.2    Shah, A.R.3    Park, T.S.4
  • 14
    • 0031868459 scopus 로고    scopus 로고
    • Hypoxic preconditioning and hypoxic-ischemic brain damage in the immature rat: Pathologic and metabolic correlates
    • Vannucci RC, Towfighi J, Vannucci SJ. Hypoxic preconditioning and hypoxic-ischemic brain damage in the immature rat: pathologic and metabolic correlates. J Neurochem 1998; 71(3): 1215-20.
    • (1998) J Neurochem , vol.71 , Issue.3 , pp. 1215-1220
    • Vannucci, R.C.1    Towfighi, J.2    Vannucci, S.J.3
  • 15
    • 0031739507 scopus 로고    scopus 로고
    • Hypoxic-ischemic tolerance phenomenon observed in neonatal rat brain
    • Ota A, Ikeda T, Abe K, et al. Hypoxic-ischemic tolerance phenomenon observed in neonatal rat brain. Am J Obstet Gynecol 1998; 179(4): 1075-8.
    • (1998) Am J Obstet Gynecol , vol.179 , Issue.4 , pp. 1075-1078
    • Ota, A.1    Ikeda, T.2    Abe, K.3
  • 16
    • 0038302338 scopus 로고    scopus 로고
    • Hypoxic preconditioning reduces apoptosis in a rat model of immature brain hypoxiaischaemia
    • Cantagrel S, Krier C, Ducrocq S, et al. Hypoxic preconditioning reduces apoptosis in a rat model of immature brain hypoxiaischaemia. Neurosci Lett 2003; 347(2): 106-10.
    • (2003) Neurosci Lett , vol.347 , Issue.2 , pp. 106-110
    • Cantagrel, S.1    Krier, C.2    Ducrocq, S.3
  • 17
    • 0034840276 scopus 로고    scopus 로고
    • Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain
    • Jones NM, Bergeron M. Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain. J Cereb Blood Flow Metab 2001; 21(9): 1105-14.
    • (2001) J Cereb Blood Flow Metab , vol.21 , Issue.9 , pp. 1105-1114
    • Jones, N.M.1    Bergeron, M.2
  • 18
    • 12844266701 scopus 로고    scopus 로고
    • Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats
    • Gustavsson M, Anderson MF, Mallard C, Hagberg H. Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats. Pediatr Res 2005; 57(2): 305-9.
    • (2005) Pediatr Res , vol.57 , Issue.2 , pp. 305-309
    • Gustavsson, M.1    Anderson, M.F.2    Mallard, C.3    Hagberg, H.4
  • 19
    • 58549085810 scopus 로고    scopus 로고
    • CREB activation in the rapid, intermediate, and delayed ischemic preconditioning against hypoxic-ischemia in neonatal rat
    • Lin WY, Chang YC, Lee HT, Huang CC. CREB activation in the rapid, intermediate, and delayed ischemic preconditioning against hypoxic-ischemia in neonatal rat. J Neurochem 2009; 108(4): 847-59.
    • (2009) J Neurochem , vol.108 , Issue.4 , pp. 847-859
    • Lin, W.Y.1    Chang, Y.C.2    Lee, H.T.3    Huang, C.C.4
  • 20
    • 23244434256 scopus 로고    scopus 로고
    • Perinatal hypoxic-ischemic brain damage: Evolution of an animal model
    • Vannucci RC, Vannucci SJ. Perinatal hypoxic-ischemic brain damage: evolution of an animal model. Dev Neurosci 2005; 27(2-4): 81-6.
    • (2005) Dev Neurosci , vol.27 , Issue.2-4 , pp. 81-86
    • Vannucci, R.C.1    Vannucci, S.J.2
  • 21
    • 0030964214 scopus 로고    scopus 로고
    • Prenatal ischemia reduces neuronal injury caused by neonatal hypoxia-ischemia in rats
    • Cai Z, Fratkin JD, Rhodes PG. Prenatal ischemia reduces neuronal injury caused by neonatal hypoxia-ischemia in rats. Neuroreport 1997; 8(6): 1393-8.
    • (1997) Neuroreport , vol.8 , Issue.6 , pp. 1393-1398
    • Cai, Z.1    Fratkin, J.D.2    Rhodes, P.G.3
  • 22
    • 0036118682 scopus 로고    scopus 로고
    • Perinatal asphyxia induced neuronal loss by apoptosis in the neonatal rat striatum: A combined TUNEL and stereological study
    • Van de Berg WD, Schmitz C, Steinbusch HW, Blanco CE. Perinatal asphyxia induced neuronal loss by apoptosis in the neonatal rat striatum: a combined TUNEL and stereological study. Exp Neurol 2002; 174(1): 29-36.
    • (2002) Exp Neurol , vol.174 , Issue.1 , pp. 29-36
    • Van de Berg, W.D.1    Schmitz, C.2    Steinbusch, H.W.3    Blanco, C.E.4
  • 23
    • 0030911477 scopus 로고    scopus 로고
    • Delayed neuronal death following perinatal asphyxia in rat
    • Dell'Anna E, Chen Y, Engidawork E, et al. Delayed neuronal death following perinatal asphyxia in rat. Exp Brain Res 1997; 115(1): 105-15.
    • (1997) Exp Brain Res , vol.115 , Issue.1 , pp. 105-115
    • Dell'Anna, E.1    Chen, Y.2    Engidawork, E.3
  • 24
    • 77549086546 scopus 로고    scopus 로고
    • Brain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning
    • Strackx E, Zoer B, Van den Hove D, et al. Brain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning. Front Biosci (Schol Ed) 2010; 2: 781-90.
    • (2010) Front Biosci (Schol Ed) , vol.2 , pp. 781-790
    • Strackx, E.1    Zoer, B.2    Van den Hove, D.3
  • 25
    • 1642489140 scopus 로고    scopus 로고
    • Neonatal hypoxia triggers transient apoptosis followed by neurogenesis in the rat CA1 hippocampus
    • Daval JL, Pourie G, Grojean S, et al. Neonatal hypoxia triggers transient apoptosis followed by neurogenesis in the rat CA1 hippocampus. Pediatr Res 2004; 55(4): 561-7.
    • (2004) Pediatr Res , vol.55 , Issue.4 , pp. 561-567
    • Daval, J.L.1    Pourie, G.2    Grojean, S.3
  • 26
    • 0037590600 scopus 로고    scopus 로고
    • Differential vulnerability of male versus female rats to long-term effects of birth insult on brain catecholamine levels
    • El-Khodor BF, Boksa P. Differential vulnerability of male versus female rats to long-term effects of birth insult on brain catecholamine levels. Exp Neurol 2003; 182(1): 208-19.
    • (2003) Exp Neurol , vol.182 , Issue.1 , pp. 208-219
    • El-Khodor, B.F.1    Boksa, P.2
  • 27
    • 0033793772 scopus 로고    scopus 로고
    • Perinatal asphyxia results in changes in presynaptic bouton number in striatum and cerebral cortex-a stereological and behavioral analysis
    • Van de Berg WD, Blokland A, Cuello AC, et al. Perinatal asphyxia results in changes in presynaptic bouton number in striatum and cerebral cortex-a stereological and behavioral analysis. J Chem Neuroanat 2000; 20(1): 71-82.
    • (2000) J Chem Neuroanat , vol.20 , Issue.1 , pp. 71-82
    • Van de Berg, W.D.1    Blokland, A.2    Cuello, A.C.3
  • 28
    • 43649083732 scopus 로고    scopus 로고
    • A combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats
    • Strackx E, Van den Hove DLA, Steinbusch HP, et al. A combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats. Exp Neurol 2008; 211(2): 413-22.
    • (2008) Exp Neurol , vol.211 , Issue.2 , pp. 413-422
    • Strackx, E.1    Van den Hove, D.L.A.2    Steinbusch, H.P.3
  • 29
    • 11844300345 scopus 로고    scopus 로고
    • Design-based stereology in neuroscience
    • Schmitz C, Hof PR. Design-based stereology in neuroscience. Neuroscience 2005; 130(4): 813-31.
    • (2005) Neuroscience , vol.130 , Issue.4 , pp. 813-831
    • Schmitz, C.1    Hof, P.R.2
  • 30
    • 77549085911 scopus 로고    scopus 로고
    • Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood
    • Strackx E, Zoer B, Van den Hove D, et al. Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood. Behav Brain Res 2010; 208(2): 343-51.
    • (2010) Behav Brain Res , vol.208 , Issue.2 , pp. 343-351
    • Strackx, E.1    Zoer, B.2    Van den Hove, D.3
  • 31
    • 0034895231 scopus 로고    scopus 로고
    • Molecular and biochemical mechanisms of perinatal injury
    • Vexler ZS, Ferriero DM. Molecular and biochemical mechanisms of perinatal injury. Semin Neonatol 2001; 6: 99-108.
    • (2001) Semin Neonatol , vol.6 , pp. 99-108
    • Vexler, Z.S.1    Ferriero, D.M.2
  • 32
    • 79952989816 scopus 로고    scopus 로고
    • A clinically relevant model of perinatal global ischemic brain damage in rats
    • Yang T, Zhuang L, Terrando N, et al. A clinically relevant model of perinatal global ischemic brain damage in rats. Brain Res 2011; 1383: 317-23.
    • (2011) Brain Res , vol.1383 , pp. 317-323
    • Yang, T.1    Zhuang, L.2    Terrando, N.3
  • 33
    • 0032875254 scopus 로고    scopus 로고
    • Inflammatory responses in the cerebral cortex after ischemia in the P7 neonatal Rat
    • Benjelloun N, Renolleau S, Represa A, Ben-Ari Y, Charriaut-Marlangue C. Inflammatory responses in the cerebral cortex after ischemia in the P7 neonatal Rat. Stroke 1999; 30(9): 1916-23.
    • (1999) Stroke , vol.30 , Issue.9 , pp. 1916-1923
    • Benjelloun, N.1    Renolleau, S.2    Represa, A.3    Ben-Ari, Y.4    Charriaut-Marlangue, C.5
  • 34
    • 80052271909 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein as a biomarker for neonatal hypoxic-ischemic encephalopathy treated with whole-body cooling
    • Ennen CS, Huisman TAGM, Savage WJ, et al. Glial fibrillary acidic protein as a biomarker for neonatal hypoxic-ischemic encephalopathy treated with whole-body cooling. Am J Obstet Gynecol 2011; 205(251): e1-7.
    • (2011) Am J Obstet Gynecol , vol.205 , Issue.251 , pp. e1-e7
    • Ennen, C.S.1    Huisman, T.A.G.M.2    Savage, W.J.3
  • 35
    • 66149094966 scopus 로고    scopus 로고
    • Activation of NF-{kappa}B is a critical element in the anti-apoptotic effect of anesthetic preconditioning
    • Lu X, Liu H, Wang L, Schaefer S. Activation of NF-{kappa}B is a critical element in the anti-apoptotic effect of anesthetic preconditioning. Am J Physiol Heart Circ Physiol 2009; 296(5): H1296-304.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , Issue.5 , pp. H1296-H1304
    • Lu, X.1    Liu, H.2    Wang, L.3    Schaefer, S.4
  • 36
    • 34147109855 scopus 로고    scopus 로고
    • Global gene expression in the developing rat brain after hypoxic preconditioning: Involvement of apoptotic mechanisms?
    • Gustavsson M, Wilson MA, Mallard C, Rousset C, Johnston MV, Hagberg H. Global gene expression in the developing rat brain after hypoxic preconditioning: involvement of apoptotic mechanisms? Pediatr Res 2007; 61(4): 444-50.
    • (2007) Pediatr Res , vol.61 , Issue.4 , pp. 444-450
    • Gustavsson, M.1    Wilson, M.A.2    Mallard, C.3    Rousset, C.4    Johnston, M.V.5    Hagberg, H.6
  • 37
    • 9144257446 scopus 로고    scopus 로고
    • cAMP response element-binding protein activation in ligation preconditioning in neonatal brain
    • Lee HT, Chang YC, Wang LY, Wang ST, Huang CC, Ho CJ. cAMP response element-binding protein activation in ligation preconditioning in neonatal brain. Ann Neurol 2004; 56(5): 611-23.
    • (2004) Ann Neurol , vol.56 , Issue.5 , pp. 611-623
    • Lee, H.T.1    Chang, Y.C.2    Wang, L.Y.3    Wang, S.T.4    Huang, C.C.5    Ho, C.J.6
  • 38
    • 0033389206 scopus 로고    scopus 로고
    • Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning
    • Gidday JM, Shah AR, Maceren RG, et al. Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning. J Cereb Blood Flow Metab 1999; 19(3): 331-40.
    • (1999) J Cereb Blood Flow Metab , vol.19 , Issue.3 , pp. 331-340
    • Gidday, J.M.1    Shah, A.R.2    Maceren, R.G.3
  • 39
    • 27744465414 scopus 로고    scopus 로고
    • Prenatal hypoxia-induced adaptation and neuroprotection that is inducible nitric oxide synthase-dependent
    • Zhao P, Zuo Z. Prenatal hypoxia-induced adaptation and neuroprotection that is inducible nitric oxide synthase-dependent. Neurobiol Dis 2005; 20(3): 871-80.
    • (2005) Neurobiol Dis , vol.20 , Issue.3 , pp. 871-880
    • Zhao, P.1    Zuo, Z.2
  • 40
    • 0034607776 scopus 로고    scopus 로고
    • Reduced nitric oxide is involved in prenatal ischemia-induced tolerance to neonatal hypoxic-ischemic brain injury in rats
    • Xiao F, Fratkin JD, Rhodes PG, Cai Z. Reduced nitric oxide is involved in prenatal ischemia-induced tolerance to neonatal hypoxic-ischemic brain injury in rats. Neurosci Lett 2000; 285(1): 5-8.
    • (2000) Neurosci Lett , vol.285 , Issue.1 , pp. 5-8
    • Xiao, F.1    Fratkin, J.D.2    Rhodes, P.G.3    Cai, Z.4
  • 41
    • 84858004799 scopus 로고    scopus 로고
    • Ischemic tolerance in the brain: Endogenous adaptive machinery against ischemic stress
    • Kitagawa K. Ischemic tolerance in the brain: endogenous adaptive machinery against ischemic stress. J Neurosci Res 2012; 90: 1043-54.
    • (2012) J Neurosci Res , vol.90 , pp. 1043-1054
    • Kitagawa, K.1
  • 43
    • 0025786082 scopus 로고
    • Glial changes following an excitotoxic lesion in the CNS-II. Astrocytes
    • Dusart I, Marty S, Peschanski M. Glial changes following an excitotoxic lesion in the CNS-II. Astrocytes. Neuroscience 1991; 45(3): 541-9.
    • (1991) Neuroscience , vol.45 , Issue.3 , pp. 541-549
    • Dusart, I.1    Marty, S.2    Peschanski, M.3
  • 44
    • 0027486952 scopus 로고
    • Control of astrocytosis by interleukin-1 and transforming growth factor-beta 1 in human brain
    • da Cunha A, Jefferson JJ, Tyor WR, Glass JD, Jannotta FS, Vitkovic L. Control of astrocytosis by interleukin-1 and transforming growth factor-beta 1 in human brain. Brain Res 1993; 631(1): 39-45.
    • (1993) Brain Res , vol.631 , Issue.1 , pp. 39-45
    • da Cunha, A.1    Jefferson, J.J.2    Tyor, W.R.3    Glass, J.D.4    Jannotta, F.S.5    Vitkovic, L.6
  • 45
    • 0035964780 scopus 로고    scopus 로고
    • Changes in reactive oxygen species (ROS) production in rat brain during global perinatal asphyxia: An ESR study
    • Capani F, Loidl CF, Aguirre F, et al. Changes in reactive oxygen species (ROS) production in rat brain during global perinatal asphyxia: an ESR study. Brain Res 2001; 914(1-2): 204-7.
    • (2001) Brain Res , vol.914 , Issue.1-2 , pp. 204-207
    • Capani, F.1    Loidl, C.F.2    Aguirre, F.3
  • 46
    • 0030972777 scopus 로고    scopus 로고
    • Astrogliosis in the neonatal and adult murine brain post-trauma: Elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma
    • Rostworowski M, Balasingam V, Chabot S, Owens T, Yong VW. Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma. J Neurosci 1997; 17(10): 3664-74.
    • (1997) J Neurosci , vol.17 , Issue.10 , pp. 3664-3674
    • Rostworowski, M.1    Balasingam, V.2    Chabot, S.3    Owens, T.4    Yong, V.W.5
  • 47
    • 20344394152 scopus 로고    scopus 로고
    • Neuroprotective role of astrocytes in cerebral ischemia: Focus on ischemic preconditioning
    • Trendelenburg G, Dirnagl U. Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning. Glia 2005; 51: 307-20.
    • (2005) Glia , vol.51 , pp. 307-320
    • Trendelenburg, G.1    Dirnagl, U.2
  • 48
    • 34247168615 scopus 로고    scopus 로고
    • The origins of the developmental origins theory
    • Barker DJ. The origins of the developmental origins theory. J Intern Med 2007; 261(5): 412-7.
    • (2007) J Intern Med , vol.261 , Issue.5 , pp. 412-417
    • Barker, D.J.1
  • 49
    • 77549085911 scopus 로고    scopus 로고
    • Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood
    • Strackx E, Van den Hove DL, Prickaerts J, et al. Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood. Behav Brain Res 2010; 208(2): 343-51.
    • (2010) Behav Brain Res , vol.208 , Issue.2 , pp. 343-351
    • Strackx, E.1    Van den Hove, D.L.2    Prickaerts, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.