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Volumn 15, Issue 1, 2015, Pages

Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer

Author keywords

Bevacizumab; Locally advanced; Rectal cancer

Indexed keywords

BEVACIZUMAB; CAPECITABINE; FLUOROURACIL; OXALIPLATIN; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN A; ANTINEOPLASTIC AGENT;

EID: 84924066421     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1052-0     Document Type: Article
Times cited : (20)

References (26)
  • 1
    • 0027404137 scopus 로고
    • Mesorectal excision for rectal cancer
    • MacFarlane JK, Ryall RD, Heald RJ. Mesorectal excision for rectal cancer. Lancet. 1993;341:457-60.
    • (1993) Lancet , vol.341 , pp. 457-460
    • MacFarlane, J.K.1    Ryall, R.D.2    Heald, R.J.3
  • 2
    • 0029152186 scopus 로고
    • Total mesorectal excision in the operative treatment of carcinoma of the rectum
    • Enker WE, Thaler HT, Cranor ML, Polyak T. Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg. 1995;181:335-46.
    • (1995) J Am Coll Surg , vol.181 , pp. 335-346
    • Enker, W.E.1    Thaler, H.T.2    Cranor, M.L.3    Polyak, T.4
  • 3
    • 0033180254 scopus 로고    scopus 로고
    • Improved survival and local control after total mesorectal excision or D3 lymphadenectomy in the treatment of primary rectal cancer: an international analysis of 1411 patients
    • Havenga K, Enker WE, Norstein J, Moriya Y, Heald RJ, van Houwelingen HC, et al. Improved survival and local control after total mesorectal excision or D3 lymphadenectomy in the treatment of primary rectal cancer: an international analysis of 1411 patients. Eur J Surg Oncol. 1999;25:368-74.
    • (1999) Eur J Surg Oncol , vol.25 , pp. 368-374
    • Havenga, K.1    Enker, W.E.2    Norstein, J.3    Moriya, Y.4    Heald, R.J.5    Houwelingen, H.C.6
  • 5
    • 33644842988 scopus 로고    scopus 로고
    • Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer
    • Rödel C, Martus P, Papadoupolos T, Füzesi L, Klimpfinger M, Fietkau R, et al. Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer. J Clin Oncol. 2005;23:8688-96.
    • (2005) J Clin Oncol , vol.23 , pp. 8688-8696
    • Rödel, C.1    Martus, P.2    Papadoupolos, T.3    Füzesi, L.4    Klimpfinger, M.5    Fietkau, R.6
  • 6
    • 77956185901 scopus 로고    scopus 로고
    • Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
    • Maas M, Nelemans PJ, Valentini V, Das P, Rödel C, Kuo L-J, et al. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. Lancet Oncol. 2010;11:835-44.
    • (2010) Lancet Oncol , vol.11 , pp. 835-844
    • Maas, M.1    Nelemans, P.J.2    Valentini, V.3    Das, P.4    Rödel, C.5    Kuo, L.-J.6
  • 7
    • 77950495945 scopus 로고    scopus 로고
    • Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2
    • Gérard J-P, Azria D, Gourgou-Bourgade S, Martel-Laffay I, Hennequin C, Etienne P-L, et al. Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2. J Clin Oncol. 2010;28:1638-44.
    • (2010) J Clin Oncol , vol.28 , pp. 1638-1644
    • Gérard, J.-P.1    Azria, D.2    Gourgou-Bourgade, S.3    Martel-Laffay, I.4    Hennequin, C.5    Etienne, P.-L.6
  • 8
    • 79960242791 scopus 로고    scopus 로고
    • Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial
    • Aschele C, Cionini L, Lonardi S, Pinto C, Cordio S, Rosati G, et al. Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial. J Clin Oncol. 2011;29:2773-80.
    • (2011) J Clin Oncol , vol.29 , pp. 2773-2780
    • Aschele, C.1    Cionini, L.2    Lonardi, S.3    Pinto, C.4    Cordio, S.5    Rosati, G.6
  • 9
    • 84886675563 scopus 로고    scopus 로고
    • Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease
    • Goel S, Wong AH-K, Jain RK. Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease. Cold Spring Harb Perspect Med. 2012;2:a006486.
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. a006486
    • Goel, S.1    Wong, A.H.-K.2    Jain, R.K.3
  • 10
    • 67649921334 scopus 로고    scopus 로고
    • Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study
    • Willett CG, Duda DG, di Tomaso E, Boucher Y, Ancukiewicz M, Sahani DV, et al. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol. 2009;27:3020-6.
    • (2009) J Clin Oncol , vol.27 , pp. 3020-3026
    • Willett, C.G.1    Duda, D.G.2    Tomaso, E.3    Boucher, Y.4    Ancukiewicz, M.5    Sahani, D.V.6
  • 11
    • 30944452436 scopus 로고    scopus 로고
    • Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients
    • Willett CG, Boucher Y, Duda DG, di Tomaso E, Munn LL, Tong RT, et al. Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients. J Clin Oncol. 2005;23:8136-9.
    • (2005) J Clin Oncol , vol.23 , pp. 8136-8139
    • Willett, C.G.1    Boucher, Y.2    Duda, D.G.3    Tomaso, E.4    Munn, L.L.5    Tong, R.T.6
  • 12
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989;10:1-10.
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 15
    • 83255194188 scopus 로고    scopus 로고
    • Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: a phase II trial
    • Kennecke H, Berry S, Wong R, Zhou C, Tankel K, Easaw J, et al. Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: a phase II trial. Eur J Cancer. 2012;48:37-45.
    • (2012) Eur J Cancer , vol.48 , pp. 37-45
    • Kennecke, H.1    Berry, S.2    Wong, R.3    Zhou, C.4    Tankel, K.5    Easaw, J.6
  • 16
    • 76049088643 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer
    • Crane CH, Eng C, Feig BW, Das P, Skibber JM, Chang GJ, et al. Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2010;76:824-30.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 824-830
    • Crane, C.H.1    Eng, C.2    Feig, B.W.3    Das, P.4    Skibber, J.M.5    Chang, G.J.6
  • 17
  • 18
    • 79956268951 scopus 로고    scopus 로고
    • Addition of bevacizumab to XELOX induction therapy plus concomitant capecitabine-based chemoradiotherapy in magnetic resonance imaging-defined poor-prognosis locally advanced rectal cancer: the AVACROSS study
    • Nogué M, Salud A, Vicente P, Arriví A, Roca JM, Losa F, et al. Addition of bevacizumab to XELOX induction therapy plus concomitant capecitabine-based chemoradiotherapy in magnetic resonance imaging-defined poor-prognosis locally advanced rectal cancer: the AVACROSS study. Oncologist. 2011;16:614-20.
    • (2011) Oncologist , vol.16 , pp. 614-620
    • Nogué, M.1    Salud, A.2    Vicente, P.3    Arriví, A.4    Roca, J.M.5    Losa, F.6
  • 19
    • 80052180910 scopus 로고    scopus 로고
    • Neoadjuvant capecitabine, radiotherapy, and bevacizumab (CRAB) in locally advanced rectal cancer: results of an open-label phase II study
    • Velenik V, Ocvirk J, Music M, Bracko M, Anderluh F, Oblak I, et al. Neoadjuvant capecitabine, radiotherapy, and bevacizumab (CRAB) in locally advanced rectal cancer: results of an open-label phase II study. Radiat Oncol. 2011;6:105.
    • (2011) Radiat Oncol , vol.6 , pp. 105
    • Velenik, V.1    Ocvirk, J.2    Music, M.3    Bracko, M.4    Anderluh, F.5    Oblak, I.6
  • 21
    • 84861569197 scopus 로고    scopus 로고
    • A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer
    • Gasparini G, Torino F, Ueno T, Cascinu S, Troiani T, Ballestrero A, et al. A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer. Angiogenesis. 2012;15:141-50.
    • (2012) Angiogenesis , vol.15 , pp. 141-150
    • Gasparini, G.1    Torino, F.2    Ueno, T.3    Cascinu, S.4    Troiani, T.5    Ballestrero, A.6
  • 22
    • 84455191894 scopus 로고    scopus 로고
    • Austrian Breast and Colorectal Cancer Study Group: Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer-a two stage phase II clinical trial
    • Resch G, De Vries A, Öfner D, Eisterer W, Rabl H, Jagoditsch M, et al. Austrian Breast and Colorectal Cancer Study Group: Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer-a two stage phase II clinical trial. Radiother Oncol. 2012;102:10-3.
    • (2012) Radiother Oncol , vol.102 , pp. 10-13
    • Resch, G.1    Vries, A.2    Öfner, D.3    Eisterer, W.4    Rabl, H.5    Jagoditsch, M.6
  • 23
    • 84861545747 scopus 로고    scopus 로고
    • Phase II study of bevacizumab and chemoradiation in the preoperative or adjuvant treatment of patients with stage II/III rectal cancer
    • Spigel DR, Bendell JC, McCleod M, Shipley DL, Arrowsmith E, Barnes EK, et al. Phase II study of bevacizumab and chemoradiation in the preoperative or adjuvant treatment of patients with stage II/III rectal cancer. Clin Colorectal Cancer. 2012;11:45-52.
    • (2012) Clin Colorectal Cancer , vol.11 , pp. 45-52
    • Spigel, D.R.1    Bendell, J.C.2    McCleod, M.3    Shipley, D.L.4    Arrowsmith, E.5    Barnes, E.K.6
  • 24
    • 84876030092 scopus 로고    scopus 로고
    • Phase 2 study of preoperative radiation with concurrent capecitabine, oxaliplatin, and bevacizumab followed by surgery and postoperative 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX), and bevacizumab in patients with locally advanced rectal cancer: ECOG 3204
    • Landry JC, Feng Y, Cohen SJ, Staley 3rd CA, Whittington R, Sigurdson ER, et al. Phase 2 study of preoperative radiation with concurrent capecitabine, oxaliplatin, and bevacizumab followed by surgery and postoperative 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX), and bevacizumab in patients with locally advanced rectal cancer: ECOG 3204. Cancer. 2013;119:1521-7.
    • (2013) Cancer , vol.119 , pp. 1521-1527
    • Landry, J.C.1    Feng, Y.2    Cohen, S.J.3    Staley, C.A.4    Whittington, R.5    Sigurdson, E.R.6
  • 25
    • 0032812135 scopus 로고    scopus 로고
    • Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90-01 randomized trial
    • Francois Y, Nemoz CJ, Baulieux J, Vignal J, Grandjean JP, Partensky C, et al. Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90-01 randomized trial. J Clin Oncol. 1999;17:2396.
    • (1999) J Clin Oncol , vol.17 , pp. 2396
    • Francois, Y.1    Nemoz, C.J.2    Baulieux, J.3    Vignal, J.4    Grandjean, J.P.5    Partensky, C.6
  • 26
    • 77955042029 scopus 로고    scopus 로고
    • A safety and survival analysis of neoadjuvant bevacizumab with standard chemoradiation in a phase I/II study compared with standard chemoradiation in locally advanced rectal cancer
    • Willett CG, Duda DG, Ancukiewicz M, Shah M, Czito BG, Bentley R, et al. A safety and survival analysis of neoadjuvant bevacizumab with standard chemoradiation in a phase I/II study compared with standard chemoradiation in locally advanced rectal cancer. Oncologist. 2010;15:845-51.
    • (2010) Oncologist , vol.15 , pp. 845-851
    • Willett, C.G.1    Duda, D.G.2    Ancukiewicz, M.3    Shah, M.4    Czito, B.G.5    Bentley, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.