-
1
-
-
0033661617
-
A proposal of three distinct subtypes of Type 1 diabetes mellitus based on clinical and pathological evidence
-
Imagawa A, Hanafusa T, Miyagawa J, Matsuzawa Y. A proposal of three distinct subtypes of Type 1 diabetes mellitus based on clinical and pathological evidence. Ann.s Med. 32(8), 539-543 (2000).
-
(2000)
Ann.S Med.
, vol.32
, Issue.8
, pp. 539-543
-
-
Imagawa, A.1
Hanafusa, T.2
Miyagawa, J.3
Matsuzawa, Y.4
-
2
-
-
84864381301
-
Fall in C-peptide during first 2 years from diagnosis: Evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data
-
Greenbaum CJ, Beam CA, Boulware D et al. Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data. Diabetes 61(8), 2066-2073 (2012).
-
(2012)
Diabetes
, vol.61
, Issue.8
, pp. 2066-2073
-
-
Greenbaum, C.J.1
Beam, C.A.2
Boulware, D.3
-
3
-
-
36448978896
-
Type 1 diabetes as a relapsing-remitting disease?
-
Von Herrath M, Sanda S, Herold K. Type 1 diabetes as a relapsing-remitting disease? Nat. Rev. Immunol. 7(12), 988-994 (2007).
-
(2007)
Nat. Rev. Immunol.
, vol.7
, Issue.12
, pp. 988-994
-
-
Von Herrath, M.1
Sanda, S.2
Herold, K.3
-
4
-
-
84876089704
-
Progress in immune-based therapies for Type 1 diabetes
-
Von Herrath M, Peakman M, Roep B. Progress in immune-based therapies for Type 1 diabetes. Clin. Exp. Immunol. 172(2), 186-202 (2013).
-
(2013)
Clin. Exp. Immunol.
, vol.172
, Issue.2
, pp. 186-202
-
-
Von Herrath, M.1
Peakman, M.2
Roep, B.3
-
5
-
-
84855525638
-
The problems and promises of research into human immunology and autoimmune disease
-
Roep BO, Buckner J, Sawcer S, Toes R, Zipp F. The problems and promises of research into human immunology and autoimmune disease. Nat. Med. 18(1), 48-53 (2012).
-
(2012)
Nat. Med.
, vol.18
, Issue.1
, pp. 48-53
-
-
Roep, B.O.1
Buckner, J.2
Sawcer, S.3
Toes, R.4
Zipp, F.5
-
6
-
-
84884170714
-
Infectious tolerance as candidate therapy for Type 1 diabetes: Transfer of immunoregulatory properties from human regulatory T cells to other T cells and proinflammatory dendritic cells
-
Kleijwegt FS, Roep BO. Infectious tolerance as candidate therapy for Type 1 diabetes: transfer of immunoregulatory properties from human regulatory T cells to other T cells and proinflammatory dendritic cells. Crit. Rev. Immunol. 33(5), 415-434 (2013).
-
(2013)
Crit. Rev. Immunol.
, vol.33
, Issue.5
, pp. 415-434
-
-
Kleijwegt, F.S.1
Roep, B.O.2
-
7
-
-
84856564903
-
GAD65 antigen therapy in recently diagnosed Type 1 diabetes mellitus
-
Ludvigsson J, Krisky D, Casas R et al. GAD65 antigen therapy in recently diagnosed Type 1 diabetes mellitus. N. Engl. J. Med. 366(5), 433-442 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, Issue.5
, pp. 433-442
-
-
Ludvigsson, J.1
Krisky, D.2
Casas, R.3
-
8
-
-
79960743608
-
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset Type 1 diabetes: A randomised double-blind trial
-
Wherrett DK, Bundy B, Becker DJ et al. Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset Type 1 diabetes: a randomised double-blind trial. Lancet 378(9788), 319-327 (2011).
-
(2011)
Lancet
, vol.378
, Issue.9788
, pp. 319-327
-
-
Wherrett, D.K.1
Bundy, B.2
Becker, D.J.3
-
9
-
-
84887052291
-
Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset Type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders
-
Herold KC, Gitelman SE, Ehlers MR et al. Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset Type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes 62(11), 3766-3774 (2013).
-
(2013)
Diabetes
, vol.62
, Issue.11
, pp. 3766-3774
-
-
Herold, K.C.1
Gitelman, S.E.2
Ehlers, M.R.3
-
10
-
-
84887025288
-
Anti-CD3 clinical trials in Type 1 diabetes mellitus
-
Daifotis AG, Koenig S, Chatenoud L, Herold KC. Anti-CD3 clinical trials in Type 1 diabetes mellitus. Clin. Immunol. 149(3), 268-278 (2013).
-
(2013)
Clin. Immunol.
, vol.149
, Issue.3
, pp. 268-278
-
-
Daifotis, A.G.1
Koenig, S.2
Chatenoud, L.3
Herold, K.C.4
-
11
-
-
84872018209
-
Recent lessons learned from prevention and recent-onset Type 1 diabetes immunotherapy trials
-
Staeva TP, Chatenoud L, Insel R, Atkinson MA. Recent lessons learned from prevention and recent-onset Type 1 diabetes immunotherapy trials. Diabetes 62(1), 9-17 (2013).
-
(2013)
Diabetes
, vol.62
, Issue.1
, pp. 9-17
-
-
Staeva, T.P.1
Chatenoud, L.2
Insel, R.3
Atkinson, M.A.4
-
12
-
-
84903721001
-
GAD-treatment of children and adolescents with recent-onset Type 1 diabetes preserves residual insulin secretion after 30 months
-
Ludvigsson J, Cheramy M, Axelsson S et al. GAD-treatment of children and adolescents with recent-onset Type 1 diabetes preserves residual insulin secretion after 30 months. Diabetes Metab. Res. Rev. 30(5), 405-414 (2014).
-
(2014)
Diabetes Metab. Res. Rev.
, vol.30
, Issue.5
, pp. 405-414
-
-
Ludvigsson, J.1
Cheramy, M.2
Axelsson, S.3
-
13
-
-
18144391496
-
Effects of oral insulin in relatives of patients with Type 1 diabetes: The Diabetes Prevention Trial - Type 1
-
Skyler JS, Krischer JP, Wolfsdorf J et al. Effects of oral insulin in relatives of patients with Type 1 diabetes: the Diabetes Prevention Trial - Type 1. Diabetes Care 28(5), 1068-1076 (2005).
-
(2005)
Diabetes Care
, vol.28
, Issue.5
, pp. 1068-1076
-
-
Skyler, J.S.1
Krischer, J.P.2
Wolfsdorf, J.3
-
14
-
-
84891812006
-
Acceleration of the loss of the first-phase insulin response during the progression to Type 1 diabetes in Diabetes Prevention Trial-Type 1 participants
-
Sosenko JM, Skyler JS, Beam CA et al. Acceleration of the loss of the first-phase insulin response during the progression to Type 1 diabetes in Diabetes Prevention Trial-Type 1 participants. Diabetes 62(12), 4179-4183 (2013).
-
(2013)
Diabetes
, vol.62
, Issue.12
, pp. 4179-4183
-
-
Sosenko, J.M.1
Skyler, J.S.2
Beam, C.A.3
-
15
-
-
84908632192
-
Blood and islet phenotypes indicate immunological heterogeneity in Type 1 diabetes
-
Arif S, Leete P, Nguyen V et al. Blood and islet phenotypes indicate immunological heterogeneity in Type 1 diabetes. Diabetes 63(11), 3835-3845 (2014).
-
(2014)
Diabetes
, vol.63
, Issue.11
, pp. 3835-3845
-
-
Arif, S.1
Leete, P.2
Nguyen, V.3
-
16
-
-
43049150180
-
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation
-
Huurman VA, Hilbrands R, Pinkse GG et al. Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. PLoS ONE 3(6), e2435 (2008).
-
(2008)
PLoS ONE
, vol.3
, Issue.6
, pp. e2435
-
-
Huurman, V.A.1
Hilbrands, R.2
Pinkse, G.G.3
-
17
-
-
84897052535
-
Immune modulation in humans: Implications for Type 1 diabetes mellitus
-
Roep BO, Tree TI. Immune modulation in humans: implications for Type 1 diabetes mellitus. Nat. Rev. Endocrinol. 10(4), 229-242 (2014).
-
(2014)
Nat. Rev. Endocrinol.
, vol.10
, Issue.4
, pp. 229-242
-
-
Roep, B.O.1
Tree, T.I.2
-
18
-
-
0033004632
-
Immunological abnormalities in islets at diagnosis paralleled further deterioration of glycaemic control in patients with recent-onset Type I (insulin-dependent) diabetes mellitus
-
Imagawa A, Hanafusa T, Itoh N et al. Immunological abnormalities in islets at diagnosis paralleled further deterioration of glycaemic control in patients with recent-onset Type I (insulin-dependent) diabetes mellitus. Diabetologia 42(5), 574-578 (1999).
-
(1999)
Diabetologia
, vol.42
, Issue.5
, pp. 574-578
-
-
Imagawa, A.1
Hanafusa, T.2
Itoh, N.3
-
19
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329(14), 977-986 (1993).
-
(1993)
N. Engl. J. Med.
, vol.329
, Issue.14
, pp. 977-986
-
-
-
20
-
-
84861913103
-
Metabolic memory for vascular disease in diabetes
-
Aschner PJ, Ruiz AJ. Metabolic memory for vascular disease in diabetes. Diabetes Technol. Ther. 14(Suppl. 1), S68-S74 (2012).
-
(2012)
Diabetes Technol. Ther.
, vol.14
, pp. S68-S74
-
-
Aschner, P.J.1
Ruiz, A.J.2
-
21
-
-
80051959785
-
Persistence of individual variations in glycated hemoglobin: Analysis of data from the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Randomized Trial
-
Wilson DM, Xing D, Cheng J et al. Persistence of individual variations in glycated hemoglobin: analysis of data from the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Randomized Trial. Diabetes Care 34(6), 1315-1317 (2011).
-
(2011)
Diabetes Care
, vol.34
, Issue.6
, pp. 1315-1317
-
-
Wilson, D.M.1
Xing, D.2
Cheng, J.3
-
22
-
-
34249820806
-
Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed Type 1 diabetes: A randomised, double-blind Phase II study
-
Lazar L, Ofan R, Weintrob N et al. Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed Type 1 diabetes: a randomised, double-blind Phase II study. Diabetes Metab. Res. Rev. 23(4), 286-291 (2007).
-
(2007)
Diabetes Metab. Res. Rev.
, vol.23
, Issue.4
, pp. 286-291
-
-
Lazar, L.1
Ofan, R.2
Weintrob, N.3
-
24
-
-
84855872623
-
Contribution of antibodies against IA-2beta and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age
-
Vermeulen I, Weets I, Asanghanwa M et al. Contribution of antibodies against IA-2beta and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age. Diabetes Care 34(8), 1760-1765 (2011).
-
(2011)
Diabetes Care
, vol.34
, Issue.8
, pp. 1760-1765
-
-
Vermeulen, I.1
Weets, I.2
Asanghanwa, M.3
-
25
-
-
0035928391
-
Type 1 diabetes: New perspectives on disease pathogenesis and treatment
-
Atkinson MA, Eisenbarth GS. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358(9277), 221-229 (2001).
-
(2001)
Lancet
, vol.358
, Issue.9277
, pp. 221-229
-
-
Atkinson, M.A.1
Eisenbarth, G.S.2
-
26
-
-
67349199566
-
Genome-wide association study and meta-analysis find that over 40 loci affect risk of Type 1 diabetes
-
Barrett JC, Clayton DG, Concannon P et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of Type 1 diabetes. Nature Genet. 41(6), 703-707 (2009).
-
(2009)
Nature Genet.
, vol.41
, Issue.6
, pp. 703-707
-
-
Barrett, J.C.1
Clayton, D.G.2
Concannon, P.3
-
27
-
-
34249786263
-
Effect of heat shock protein peptide DiaPep277 on beta-cell function in paediatric and adult patients with recent-onset diabetes mellitus Type 1: Two prospective, randomized, double-blind Phase II trials
-
Schloot NC, Meierhoff G, Lengyel C et al. Effect of heat shock protein peptide DiaPep277 on beta-cell function in paediatric and adult patients with recent-onset diabetes mellitus Type 1: two prospective, randomized, double-blind Phase II trials. Diabetes Metab. Res. Rev. 23(4), 276-285 (2007).
-
(2007)
Diabetes Metab. Res. Rev.
, vol.23
, Issue.4
, pp. 276-285
-
-
Schloot, N.C.1
Meierhoff, G.2
Lengyel, C.3
-
28
-
-
84891763324
-
Multiple HLA epitopes contribute to Type 1 diabetes susceptibility
-
Roark CL, Anderson KM, Simon LJ, Schuyler RP, Aubrey MT, Freed BM. Multiple HLA epitopes contribute to Type 1 diabetes susceptibility. Diabetes 63(1), 323-331 (2014).
-
(2014)
Diabetes
, vol.63
, Issue.1
, pp. 323-331
-
-
Roark, C.L.1
Anderson, K.M.2
Simon, L.J.3
Schuyler, R.P.4
Aubrey, M.T.5
Freed, B.M.6
-
29
-
-
4344648997
-
Genotype effects and epistasis in Type 1 diabetes and HLA-DQ trans dimer associations with disease
-
Koeleman BP, Lie BA, Undlien DE et al. Genotype effects and epistasis in Type 1 diabetes and HLA-DQ trans dimer associations with disease. Genes Immun. 5(5), 381-388 (2004).
-
(2004)
Genes Immun.
, vol.5
, Issue.5
, pp. 381-388
-
-
Koeleman, B.P.1
Lie, B.A.2
Undlien, D.E.3
-
30
-
-
0027263221
-
Immunogenetic and clinical characterization of slowly progressive IDDM
-
Kobayashi T, Tamemoto K, Nakanishi K et al. Immunogenetic and clinical characterization of slowly progressive IDDM. Diabetes Care 16, 780-788 (1993).
-
(1993)
Diabetes Care
, vol.16
, pp. 780-788
-
-
Kobayashi, T.1
Tamemoto, K.2
Nakanishi, K.3
-
31
-
-
0028674264
-
Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
-
Harrison LC, Honeyman MC, De Aizpurua HJ et al. Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. J. Endocrinol. Invest. 17, 581-581 (1994).
-
(1994)
J. Endocrinol. Invest.
, vol.17
, pp. 581-581
-
-
Harrison, L.C.1
Honeyman, M.C.2
De Aizpurua, H.J.3
-
32
-
-
0030051666
-
HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus
-
Roep BO, Duinkerken G, Schreuder GM, Kolb H, De VR, Martin S. HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus. Eur. J. Immunol. 26(6), 1285-1289 (1996).
-
(1996)
Eur. J. Immunol.
, vol.26
, Issue.6
, pp. 1285-1289
-
-
Roep, B.O.1
Duinkerken, G.2
Schreuder, G.M.3
Kolb, H.4
De, V.R.5
Martin, S.6
-
33
-
-
34249665017
-
GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for Type 1 diabetes
-
Mayr A, Schlosser M, Grober N et al. GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for Type 1 diabetes. Diabetes 56(6), 1527-1533 (2007).
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1527-1533
-
-
Mayr, A.1
Schlosser, M.2
Grober, N.3
-
34
-
-
0035807589
-
Development of Type 1 diabetes despite severe hereditary B-lymphocyte deficiency
-
Martin S, Wolf-Eichbaum D, Duinkerken G et al. Development of Type 1 diabetes despite severe hereditary B-lymphocyte deficiency. N. Engl. J. Med. 345(14), 1036-1040 (2001).
-
(2001)
N. Engl. J. Med.
, vol.345
, Issue.14
, pp. 1036-1040
-
-
Martin, S.1
Wolf-Eichbaum, D.2
Duinkerken, G.3
-
35
-
-
4344690190
-
Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to Type 1 diabetes
-
Achenbach P, Koczwara K, Knopff A, Naserke H, Ziegler AG, Bonifacio E. Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to Type 1 diabetes. J. Clin. Invest. 114(4), 589-597 (2004).
-
(2004)
J. Clin. Invest.
, vol.114
, Issue.4
, pp. 589-597
-
-
Achenbach, P.1
Koczwara, K.2
Knopff, A.3
Naserke, H.4
Ziegler, A.G.5
Bonifacio, E.6
-
36
-
-
84901452215
-
GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial
-
Krause S, Landherr U, Agardh CD et al. GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial. Diabetes Care 37(6), 1675-1680 (2014).
-
(2014)
Diabetes Care
, vol.37
, Issue.6
, pp. 1675-1680
-
-
Krause, S.1
Landherr, U.2
Agardh, C.D.3
-
37
-
-
34548397755
-
Screening for insulitis in adult autoantibody-positive organ donors
-
In't VP, Lievens D, De GJ et al. Screening for insulitis in adult autoantibody-positive organ donors. Diabetes 56(9), 2400-2404 (2007).
-
(2007)
Diabetes
, vol.56
, Issue.9
, pp. 2400-2404
-
-
In'T, V.P.1
Lievens, D.2
De, G.J.3
-
38
-
-
80053416976
-
Evidence that HLA class I and II associations with Type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct
-
Howson JM, Stevens H, Smyth DJ et al. Evidence that HLA class I and II associations with Type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct. Diabetes 60(10), 2635-2644 (2011).
-
(2011)
Diabetes
, vol.60
, Issue.10
, pp. 2635-2644
-
-
Howson, J.M.1
Stevens, H.2
Smyth, D.J.3
-
39
-
-
0035140996
-
Proposed guidelines on screening for risk of Type 1 diabetes
-
Bingley PJ, Bonifacio E, Ziegler AG, Schatz DA, Atkinson MA, Eisenbarth GS. Proposed guidelines on screening for risk of Type 1 diabetes. Diabetes Care 24(2), 398 (2001).
-
(2001)
Diabetes Care
, vol.24
, Issue.2
, pp. 398
-
-
Bingley, P.J.1
Bonifacio, E.2
Ziegler, A.G.3
Schatz, D.A.4
Atkinson, M.A.5
Eisenbarth, G.S.6
-
40
-
-
84879114358
-
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children
-
Ziegler AG, Rewers M, Simell O et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 309(23), 2473-2479 (2013).
-
(2013)
JAMA
, vol.309
, Issue.23
, pp. 2473-2479
-
-
Ziegler, A.G.1
Rewers, M.2
Simell, O.3
-
41
-
-
79960912796
-
Co-stimulation modulation with abatacept in patients with recent-onset Type 1 diabetes: A randomised, double-blind, placebo-controlled trial
-
Orban T, Bundy B, Becker DJ et al. Co-stimulation modulation with abatacept in patients with recent-onset Type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet 378(9789), 412-419 (2011).
-
(2011)
Lancet
, vol.378
, Issue.9789
, pp. 412-419
-
-
Orban, T.1
Bundy, B.2
Becker, D.J.3
-
42
-
-
84897851090
-
Costimulation modulation with abatacept in patients with recent-onset Type 1 diabetes: Follow-up 1 year after cessation of treatment
-
Orban T, Bundy B, Becker DJ et al. Costimulation modulation with abatacept in patients with recent-onset Type 1 diabetes: follow-up 1 year after cessation of treatment. Diabetes Care 37(4), 1069-1075 (2014).
-
(2014)
Diabetes Care
, vol.37
, Issue.4
, pp. 1069-1075
-
-
Orban, T.1
Bundy, B.2
Becker, D.J.3
-
43
-
-
34249825219
-
Therapy with the hsp60 peptide DiaPep277 in C-peptide positive Type 1 diabetes patients
-
Huurman VA, Decochez K, Mathieu C, Cohen IR, Roep BO. Therapy with the hsp60 peptide DiaPep277 in C-peptide positive Type 1 diabetes patients. Diabetes Metab. Res. Rev. 23(4), 269-275 (2007).
-
(2007)
Diabetes Metab. Res. Rev.
, vol.23
, Issue.4
, pp. 269-275
-
-
Huurman, V.A.1
Decochez, K.2
Mathieu, C.3
Cohen, I.R.4
Roep, B.O.5
-
44
-
-
43349090939
-
Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical Type I diabetes
-
Huurman VA, Van Der Meide PE, Duinkerken G et al. Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical Type I diabetes. Clin. Exp. Immunol. 152(3), 488-497 (2008).
-
(2008)
Clin. Exp. Immunol.
, vol.152
, Issue.3
, pp. 488-497
-
-
Huurman, V.A.1
Van Der Meide, P.E.2
Duinkerken, G.3
-
45
-
-
34249812097
-
Treatment of new-onset Type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: Extension of a randomized, double-blind, Phase II trial
-
Raz I, Avron A, Tamir M et al. Treatment of new-onset Type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomized, double-blind, Phase II trial. Diabetes Metab. Res. Rev. 23(4), 292-298 (2007).
-
(2007)
Diabetes Metab. Res. Rev.
, vol.23
, Issue.4
, pp. 292-298
-
-
Raz, I.1
Avron, A.2
Tamir, M.3
-
46
-
-
55249110198
-
GAD treatment and insulin secretion in recent-onset Type 1 diabetes
-
Ludvigsson J, Faresjo M, Hjorth M et al. GAD treatment and insulin secretion in recent-onset Type 1 diabetes. N. Engl. J. Med. 359(18), 1909-1920 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, Issue.18
, pp. 1909-1920
-
-
Ludvigsson, J.1
Faresjo, M.2
Hjorth, M.3
-
47
-
-
79953756466
-
Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset Type 1 diabetes: A randomised controlled trial
-
Ludvigsson J, Hjorth M, Cheramy M et al. Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset Type 1 diabetes: a randomised controlled trial. Diabetologia 54(3), 634-640 (2011).
-
(2011)
Diabetologia
, vol.54
, Issue.3
, pp. 634-640
-
-
Ludvigsson, J.1
Hjorth, M.2
Cheramy, M.3
-
48
-
-
84887055430
-
Teplizumab preserves C-peptide in recent-onset Type 1 diabetes: Two-year results from the randomized, placebo-controlled Protege trial
-
Hagopian W, Ferry RJ Jr, Sherry N et al. Teplizumab preserves C-peptide in recent-onset Type 1 diabetes: two-year results from the randomized, placebo-controlled Protege trial. Diabetes 62(11), 3901-3908 (2013).
-
(2013)
Diabetes
, vol.62
, Issue.11
, pp. 3901-3908
-
-
Hagopian, W.1
Ferry, R.J.2
Sherry, N.3
-
49
-
-
80051471700
-
Teplizumab for treatment of Type 1 diabetes (Protege study): 1-year results from a randomised, placebo-controlled trial
-
Sherry N, Hagopian W, Ludvigsson J et al. Teplizumab for treatment of Type 1 diabetes (Protege study): 1-year results from a randomised, placebo-controlled trial. Lancet 378(9790), 487-497 (2011).
-
(2011)
Lancet
, vol.378
, Issue.9790
, pp. 487-497
-
-
Sherry, N.1
Hagopian, W.2
Ludvigsson, J.3
-
50
-
-
70449480577
-
Rituximab, B-lymphocyte depletion, and preservation of beta-cell function
-
Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H et al. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. N. Engl. J. Med. 361(22), 2143-2152 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, Issue.22
, pp. 2143-2152
-
-
Pescovitz, M.D.1
Greenbaum, C.J.2
Krause-Steinrauf, H.3
-
51
-
-
55749104546
-
Nasal insulin to prevent Type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: A double-blind, randomised controlled trial
-
Nanto-Salonen K, Kupila A, Simell S et al. Nasal insulin to prevent Type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial. Lancet 372(9651), 1746-1755 (2008).
-
(2008)
Lancet
, vol.372
, Issue.9651
, pp. 1746-1755
-
-
Nanto-Salonen, K.1
Kupila, A.2
Simell, S.3
-
52
-
-
78149475225
-
Dietary intervention in infancy and later signs of beta-cell autoimmunity
-
Knip M, Virtanen SM, Seppa K et al. Dietary intervention in infancy and later signs of beta-cell autoimmunity. N. Engl. J. Med. 363(20), 1900-1908 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, Issue.20
, pp. 1900-1908
-
-
Knip, M.1
Virtanen, S.M.2
Seppa, K.3
-
53
-
-
84887625697
-
Immune intervention therapy in Type 1 diabetes: Safety first
-
Roep BO. Immune intervention therapy in Type 1 diabetes: safety first. Lancet Diabetes Endocrinol. 1(4), 263-265 (2013).
-
(2013)
Lancet Diabetes Endocrinol.
, vol.1
, Issue.4
, pp. 263-265
-
-
Roep, B.O.1
-
54
-
-
84887625676
-
Low-dose interleukin 2 in patients with Type 1 diabetes: A Phase 1/2 randomised, double-blind, placebo-controlled trial
-
Hartemann A, Bensimon G, Payan CA et al. Low-dose interleukin 2 in patients with Type 1 diabetes: a Phase 1/2 randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol. 1(4), 295-305 (2013).
-
(2013)
Lancet Diabetes Endocrinol.
, vol.1
, Issue.4
, pp. 295-305
-
-
Hartemann, A.1
Bensimon, G.2
Payan, C.A.3
-
55
-
-
84865478468
-
Rapamycin/IL-2 combination therapy in patients with Type 1 diabetes augments Tregs yet transiently impairs beta-cell function
-
Long SA, Rieck M, Sanda S et al. Rapamycin/IL-2 combination therapy in patients with Type 1 diabetes augments Tregs yet transiently impairs beta-cell function. Diabetes 61(9), 2340-2348 (2012).
-
(2012)
Diabetes
, vol.61
, Issue.9
, pp. 2340-2348
-
-
Long, S.A.1
Rieck, M.2
Sanda, S.3
-
57
-
-
77950649733
-
Group I-JTDCTA: Developing combination immunotherapies for Type 1 diabetes: Recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
-
Matthews JB, Staeva TP, Bernstein PL, Peakman M, Von Herrath M. Group I-JTDCTA: developing combination immunotherapies for Type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin. Exp. Immunol. 160(2), 176-184 (2010).
-
(2010)
Clin. Exp. Immunol.
, vol.160
, Issue.2
, pp. 176-184
-
-
Matthews, J.B.1
Staeva, T.P.2
Bernstein, P.L.3
Peakman, M.4
Von Herrath, M.5
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