Tuberculosis in children

Cold Spring Harbor Perspectives in Medicine

Volumn 4, Issue 9, 2014, Pages

  Marais, Ben J ^a   Schaaf, H Simon ^b  

^a University of Sydney   (Australia)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHILD; CHILDHOOD MORTALITY; CLINICAL EVALUATION; DISEASE COURSE; GROUPS BY AGE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LABORATORY; LABORATORY TEST; LUNG TUBERCULOSIS; LYMPHADENITIS; LYMPHADENOPATHY; PERICARDIAL EFFUSION; PLEURA EFFUSION; POVERTY; SOCIAL ASPECT; TUBERCULOSIS; TUBERCULOUS MENINGITIS; HEALTH; MORBIDITY; TRENDS;

HUMAN IMMUNODEFICIENCY VIRUS;

CHILD; GLOBAL HEALTH; HUMANS; MORBIDITY; POVERTY; TUBERCULOSIS;

EID: 84923899650     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a017855     Document Type: Article

References (67)

1. Abubakar I, Ford N, Cox H. 2013. The rising tide of drugresistant tuberculosis—Time for visionary political leadership. Lancet Infect Dis 13: 529–539.
2. Amanullah F, Ashfaq M, Khowaja S, Parekh A, Salahuddin N, Lotia-Farrukh I, Khan A, Becerra MC. 2014. High tuberculosis prevalence in children exposed at home to drug-resistant tuberculosis. Int J Tuberc Lung Dis 18: 520–527.
3. Andronikou S, van Hoenacker FM, de Backer AI. 2009. Advances in imaging chest tuberculosis: Blurring-of-differencesbetween-children-and-adults. Clin Chest Med 30: 717–744.
4. Bates M, Mudenda V, Mwaba P, Zumla A. 2013. Deaths due to respiratory tract infections in Africa: A review of autopsy studies. Curr Opin Pulm Med 19: 229–237.
5. Blanc FX, Sok T, Laureillard D, Borand L, Rekacewicz C, Nerrienet E, Madec Y, Marcy O, Chan S, Prak N, et al. 2011. Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis. N Engl JMed 365: 1471–1481.
6. Cotton MF, Schaaf HS, Lottering G, Wever HL, Coetzee J,Nachman S. 2008. Tuberculosis exposure in HIV-exposed infants in a high-prevalence setting. Int J Tuberc Lung Dis 12: 225–227.
7. Du Preez K, Schaaf HS, Dunbar R, Swartz A, Bissell K, Enarson DA, Hessling AC. 2011. Incomplete registration and reporting of culture-confirmed childhood tuberculosis diagnosed in hospital. Public Health Action 1: 19-24.
8. Edwards DJ, Kitelele F, van Rie A. 2007. Agreement between clinical scoring systems used for the diagnosis of tuberculosis in the HIVera. Int J Tuberc Lung 11: 263–269.
9. Ettehad D, Schaaf HS, Seddon JA, Cooke G, Ford N. 2012. Treatment outcomes for children with multi-drug resistant tuberculosis: A systematic review and meta-analysis. Lancet Infect Dis 12: 449–456.
10. Gie RP. 2003. Diagnostic atlas of intrathoracic tuberculosis in children: A guide for low income countries. IUATLD, Paris. http://www.theunion.org/download/clh/diagnostic_atlas_intrathoraric_tuberculosis_child.pdf.
11. Graham SM, Sismanidis C, Menzies HJ, Marais BJ, Detjen AK, Black RE. 2014. Importance of tuberculosis control to address child survival. Lancet 383: 1605–1607.
12. Hesseling AC, Schaaf HS, Gie RP, Starke JR, Beyers N. 2002. A critical review of diagnostic approaches used in the diagnosis of childhood tuberculosis. Int J Tuberc Lung Dis 6: 1038–1045.
13. Hesseling AC, Marais BJ, Gie RP, Schaaf HS, Fine PEM, Godfrey-Faussett P, Beyers N. 2007. The risk of disseminated bacilli Calmette–Gue´rin (BCG) disease in HIVinfected children. Vaccine 25: 14–18.
14. Hesseling AC, Cotton MF, Jennings T, Whitelaw A, Johnson LF, Eley B, Roux P, Godfrey-Faussett P, Schaaf HS. 2009. High incidence of tuberculosis among HIV-infected infants: Evidence from a South African population-based study highlights the need for improved tuberculosis control strategies. Clin Infect Dis 48: 108–114.
15. Hill PC, Rutherford ME, Audas R, van Crevel R, Graham SM. 2011. Closing the policy-practice gap in the management of child contacts of tuberculosis in developing countries. PLoS Med 8: 10001105.
16. IUATLD. 2010. Desk-guide for the diagnosis and management of TB in children. www.theunion.org/index.php/en/resources/scientific-publications/tuberculosis/item/193-desk-guide-for-diagnosis-and-managementof-tb-in-children.
17. Jenkins HE, Tolman AW, Yuen CM, Parr JB, Keshavjee S, Perez-Velez CM, Pagano M, Becerra MC, Cohen T. 2014. Incidence of multidrug-resistant tuberculosis disease in children: Systematic review and global estimates. Lancet 383: 1572–1579.
18. Källenius G. 2014. Tuberculosis and HIV coinfections. Cold Spring Harb Perspect Med doi: 10.1101/cshperspect.a017871.
19. Lawn SD, Bekker LG, Middelkoop K, Myer L, Wood R. 2006. Impact of HIV infection on the epidemiology of tuberculosis in a peri-urban community in South Africa: The need for age-specific interventions. Clin Infect Dis 42: 1040–1047.
20. Lincoln EM, Sewell EM. 1963. Tuberculosis in children. McGraw-Hill, New York.
21. Marais BJ, Pai M. 2006. Specimen collection methods in the diagnosis of childhood tuberculosis. Indian J Med Microbiol 24: 249–251.
22. Marais BJ, Gie RP, Schaaf HS, Hesseling AC, Obihara CC, Starke JJ, Enarson DA, Donald PR, Beyers N. 2004a. The natural history of childhood intra-thoracic tuberculosis:A critical review of literature from the pre-chemotherapy era. Int J Tuberc Lung Dis 8: 392–402.
23. Marais BJ, Gie RP, Schaaf HS, Starke JR, Hesseling AC, Donald PR, Beyers N. 2004b. A proposed radiologic classification of childhood intra-thoracic tuberculosis. Pediatr Rad 33: 886–894.
24. Marais BJ, Donald PR, Gie RP, Schaaf HS, Beyers N. 2005a. Diversity of disease manifestations in childhood pulmonary tuberculosis. Ann Trop Paed 25: 79–86.
25. Marais BJ, Obihara CC, Warren RM, Schaaf HS, Gie RP, Donald PR. 2005b. The burden of childhood tubercuosis: A public health perspective. Int J Tuberc Lung Dis 9: 1305–1313.
26. Marais BJ, Gie RP, Schaaf HS, Hesseling AC, Enarson DA, Beyers N. 2006a. The spectrum of disease in children treated for tuberculosis in a highly endemic area. Int J Tuberc Lung Dis 10: 732–738.
27. Marais BJ, Wright CA, Schaaf HS, Gie RP, Hesseling AC, Enarson DA, Beyers N. 2006b. Tuberculous lymphadenitis as a cause of persistent cervical lymphadenopathy in children from a tuberculosis-endemic area. Pediatr Inf Dis J 25: 142–146.
28. Marais BJ, Gie RP, Hesseling AC, Schaaf HS, Lombard C, Enarson DA, Beyers N. 2006c. A refined symptom-based approach to diagnose pulmonary tuberculosis in children. Pediatrics 118: e1350–e1359.
29. Marais BJ, Ayles H, Graham SM, Godfrey-Faussett P. 2009. Screening and preventive therapy for tuberculosis. Chest Clin N Am 30: 827–846.
30. Marais B, Graham S, Maeurer M, Zumla A. 2013a. Progress and challenges in childhood tuberculosis. Lancet Infect Dis 13: 287–289.
31. Marais BJ, Mlambo CK, Rastogi N, Zozio T, Duse AG,Victor TC, Marais E, Warren RM. 2013b. Epidemic spread of multidrug-resistant (MDR) tuberculosis in Johannesburg, South Africa. J Clin Microbiol 51: 1818–1825.
32. Marais S, Meintjes G, Pepper DJ, Dodd LE, Schutz C, Ismail Z, Wilkinson KA, Wilkinson RJ. 2013c. Frequency, severity, and prediction of tuberculous meningitis immune reconstitution inflammatory syndrome. Clin Infect Dis 56: 450–460.
33. Meintjes G, Rabie H, Wilkinson RJ, Cotton MF. 2009. Tuberculosis associated immune reconstitution inflammatory syndrome and unmasking of tuberculosis by antiretroviral therapy. Clin Chest Med 30: 797–810.
34. MMWR. 2010. Updated guidelines for using interferon gamma release assays to detect Mycobacterium tuberculosis infection—United States. MMWR 59: 1–25.
35. Muñoz FM, Ong LT, Seavy D, Medina D, Correa A, Starke JR. 2002. Tuberculosis among adult visitors of children with suspected tuberculosis and employees at a children’s hospital. Infect Control Hosp Epidemiol 23: 568–572.
36. Newton SM, Brent AJ, Anderson S, Whittaker E, Kampmann B. 2008. Paediatric tuberculosis. Lancet Infect Dis 8: 499–510.
37. Nicol MP, Zar HJ. 2011. New specimens and laboratory diagnostics for childhood pulmonary TB: Progress and prospects. Paediatr Respir Rev 12: 16–21.
38. Nicol MP, Workman L, Isaacs W, Munro J, Eley B, Boehme CC, Zemanay W, Zar HJ. 2011. Accuracy of the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in children admitted to hospital in Cape Town, South Africa: A descriptive study. Lancet Infect Dis 11: 819–824.
39. Nicol MP, Spiers K,Workman L, IsaacsW,Munro J, Black F, Zemanay W, Zar HJ. 2013. Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children. Clin Infect Dis 57: e18–e21.
40. Perez-Velez CM, Marais BJ. 2012. Tuberculosis in children. N Engl J Med 367: 348–361.
41. Perez-Velez CM, Wilches-Luna EC, Hernández-Sarmiento JM, Casanova-Reynolds AL, Hernández N, Moreno-Ortega SP, Atehortuá-Muñoz SL, Rozo-Anaya JC, Mejĺa GI, Gómez V, et al. 2010. Preliminary results of a comparative yield study of induced sputum, string test, and gastric aspirate for the microbiological diagnosis of pulmonary tuberculosis in children. Am J Respir Crit Care Med 181: A1775.
42. Pienaar M, Andronikou S, van Toorn R. 2009. MRI to demonstrate diagnostic features and complications of TBM not seen with CT. Child Nerv Syst 25: 941–947.
43. Rabie H, Violari A, Duong T, Madhi SA, Josipovic D, Innes S, Dobbels E, Lazarus E, Panchia R, Babiker AG, et al. 2011. Early antiretroviral treatment reduces risk of bacille Calmette–Gue´rin immune reconstitution adenitis. Int J Tuberc Lung Dis 15: 1194–1200.
44. Rachow A, Clowes P, Saathoff E, Mtafya B, Ntinginya EN, Kowour D, Rojas-Ponce G, Kroidl A, Maboko L, Heinrich N, et al. 2012. Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: A prospective cohort study. Clin Infect Dis 54: 1388–1396.
45. Rose PC, Schaaf HS, du Preez K, Seddon JA, Garcia-Prass AJ, Zimri K, Dunbar R, Hesseling AC. 2013. Completeness and accuracy of paediatric electronic drug-resistant tuberculosis registration in Cape Town, South Africa. Public Health Action 3: 214–219.
46. Schaaf HS, Van Rie A, Gie RP, Beyers N, Victor TC, Van Helden PD, Donald PR. 2000. Transmission of multirug resistant tuberculosis. Pediatr Infect Dis J 19: 695-699.
47. Schaaf HS, Marais BJ, Whitelaw A, Hesseling AC, Eley B, Hussey GD, Donald PR. 2007. Culture-confirmed childhood tuberculosis in Cape Town, South Africa: A review of 596 cases. BMC Infect Dis 7: 140.
48. Schaaf HS, Collins A, Bekker A, Davies PDO. 2010. Tuberculosis at the extremes of age. Respirology 15: 747–763.
49. Schaaf HS, Cotton MF, Boon GPG, Jeena PM. 2013. Isoniazid preventive therapy in HIV-infected and uninfected children (0–14 years). S Afr Med J 103: 714–715.
50. Seddon JA, Furin JJ, Gale M, Del Castillo Barrientos H, Hurtado RM, Amanullah F, Ford N, Starke JR, Schaaf HS, Sentinel Project on Pediatric Drug-Resistant Tuberculosis. 2012. Caring for children with drug-resistant tuberculosis: Practice-based recommendations. AmJ Respir Crit Care Med 186: 953–964.
51. Seddon JA, Hesseling AC, Finlayson H, Fielding K, Cox H, Hughes J, Godfrey-Faussett P, Schaaf HS. 2013. Preventive therapy for child contacts of multidrug-resistant tuberculosis: A prospective cohort study. Clin Infect Dis 57: 1676–1684.
52. Seung KJ, Rich M, Keshavjee S. 2014. MDR and XDR tuberculosis. Cold Spring Harb Perspect Med doi: 10.1101/cshperspect.a017863.
53. Siberry GK, Abzug MJ, Nachman S, the Panel on Opportunistic Infections in HIV-Exposed and HIV-Infected Children. 2013. Guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children: Recommendations from theNational Institutes of Health, Centers for Disease Control and Prevention, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics. Pediatr Infect Dis J 32.
54. Spyridis NP, Spyridis PG, Gelesme A, Sypsa V, Valianatou M, Metsou F, Gourgiotis D, Tsolia MN. 2007. The effectiveness of a 9-month regimen of isoniazid alone versus 3-and 4-month regimens of isoniazid plus rifampin for treatment of latent tuberculosis infection in children: Results of an 11-year randomized study. Clin Infect Dis 45: 715–722.
55. Sterling TR, Villarino ME, Borisov AS, Shang N, Gordin F, Bliven-Sizemore E, Hackman J, Hamilton CD, Menzies D, et al. 2011. Three months of rifapentine and isoniazid for latent tuberculosis infection. N Eng J Med 365: 2155–2166.
56. Thwaites GE, van Toorn R, Schoeman J. 2013. Tuberculous meningitis: More questions, still too few answers. Lancet Neurol 12: 999–1010.
57. Török ME, Yen NT, Chau TT, Mai NT, Phu NH, Mai PP, Dung NT, Chau NV, Bang ND, Tien NA, et al. 2011. Timing of initiation of antiretroviral therapy in human immunodeficiency virus (HIV)-associated tuberculous meningitis. Clin Infect Dis 52: 1374–1383.
58. Trunz BB, Fine P, Dye C. 2006. Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: A meta-analysis and assessment of costeffectiveness. Lancet 367: 1173–1180.
59. Violari A, Cotton MF, Gibb DM, Babiker AG, Steyn J, Madhi SA, Jean-Philippe P, McIntyre JA, CHER Study Team. 2008. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 359: 2233-2244.
60. Wallgren A. 1948. The time-table of tuberculosis. Tubercle 29: 245–251.
61. WHO Press. 2014. Guidance for national tuberculosis programmes on the management of tuberculosis in children, 2nd ed. Geneva, Switzerland (WHO/HTM/TB/2014.03).
62. WorldHealth Organization. 2007. Revised BCG vaccination guideline for infants at risk of HIV infection. Wkly Edimiol Rev 82: 193.
63. World Health Organization. 2011a. Use of tuberculosis interferon-g release assays (IGRAs) in low and middle income countries: Policy statement. Geneva, WHO Press.
64. World Health Organization. 2011. Guidelines for intensified TB case-finding and INH preventive therapy for people living with HIV in resource-constrained settings: Annexes. WHO Press, Geneva. http://whqlibdoc.who.int/publications/2011/9789241500708_annexes_eng.pdf.
65. World Health Organization. 2013. Global Tuberculosis Report 2013. World Health Organisation, Geneva. WHO/HTM/TB/2013.
66. Wright CA, Warren RW, Marais BJ. 2009. Fine needle aspiration biopsy: An undervalued diagnostic modality in pediatric mycobacterial disease. Int J Tuberc Lung Dis 13: 1467–1475.
67. Zignol M, Sismanidis C, Falzon D, Glaziou P, Dara M, Floyd K. 2013. Multidrug-resistant tuberculosis in children: Evidence from global surveillance. Eur Respir J 42: 701–707.