Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses

American Journal of Respiratory and Critical Care Medicine

Volumn 191, Issue 5, 2015, Pages 547-556

  Dijkstra, Akkelies E ^a   Postma, Dirkje S ^a   van Ginneken, Bram ^b,c   Wielpütz, Mark O ^d,e,f   Schmidt, Michael ^c   Becker, Nikolaus ^f   Owsijewitsch, Michael ^d,e,f   Kauczor, Hans Ulrich ^d,e   De Koning, Harry J ^g   Lammers, Jan W ^h   Oudkerk, Matthijs ^a   Brandsma, Corry Anke ^a   Bossé, Yohan ⁱ   Nickle, David C ^j   Sin, Don D ^k   Hiemstra, Pieter S ^l   Wijmenga, Ciska ^a   Smolonska, Joanna ^a   Zanen, Pieter ^h   Vonk, Judith M ^a,m   Van Den Berge, Maarten ^a   Boezen, H Marike ^a,m   Groen, Harry J M ^a   more..

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c FRAUNHOFER MEVIS   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e German Center for Lung Research   (Germany)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g ERASMUS MEDICAL CENTER   (Netherlands)

^h UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

ⁱ LAVAL UNIVERSITY   (Canada)

^j MERCK RESEARCH LABORATORIES   (United States)

^k UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^l LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^m UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

more..

Author keywords

Airway wall thickening; COPD; CT scan; Genetics; Smoking

Indexed keywords

ADULT; AIRWAY WALL THICKNESS; ARTICLE; BRONCHUS BIOPSY; CANCER SCREENING; CHROMOSOME 10Q; CHROMOSOME 2Q; CHRONIC OBSTRUCTIVE LUNG DISEASE; COHORT ANALYSIS; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; EMPHYSEMA; ENVIRONMENTAL FACTOR; GENE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEREDITY; HUMAN; HUMAN TISSUE; LIMIT OF QUANTITATION; LOW ENERGY RADIATION; LUNG CANCER; LUNG FUNCTION; LUNG VOLUME; MAGI2 GENE; MAJOR CLINICAL STUDY; MALE; NT5C3B GENE; OPEN READING FRAME; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RESPIRATORY TRACT PARAMETERS; SERPINE2 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; THICKNESS; AGED; AIRWAY REMODELING; CHROMOSOME 10; CHROMOSOME 2; FEMALE; GENETIC PREDISPOSITION; GENETICS; LUNG EMPHYSEMA; MIDDLE AGED;

5' NUCLEOTIDASE; CARRIER PROTEIN; GLYCOPROTEIN; MAGI2 PROTEIN, HUMAN; NT5C3 PROTEIN, HUMAN; PROTEASE NEXIN I; SERPINE2 PROTEIN, HUMAN;

5'-NUCLEOTIDASE; AGED; AIRWAY REMODELING; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 2; FEMALE; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GLYCOPROTEINS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; SERPIN E2; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84923875674     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201405-0840OC     Document Type: Article

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