Non-invasive screening for Alzheimer's disease by sensing salivary sugar using Drosophila cells expressing gustatory receptor (Gr5a) immobilized on an extended gate ion-sensitive field-effect transistor (EG-ISFET) biosensor

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Lau, Hui Chong ^a   Lee, In Kyu ^b   Ko, Pan Woo ^c   Lee, Ho Won ^a   Huh, Jeung Soo ^a   Cho, Won Ju ^b   Lim, Jeong Ok ^a  

^a Kyungpook National University   (South Korea)

^b Kwangwoon University   (South Korea)

^c Daegu Medical Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GUSTATORY RECEPTOR 5A; RECEPTOR; TREHALOSE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; GUSTATORY RECEPTOR, DROSOPHILA;

AGED; ALZHEIMER DISEASE; ARTICLE; BIOSENSOR; CLINICAL ARTICLE; CONTROLLED STUDY; DROSOPHILA; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTENDED GATE ION SENSITIVE FIELD EFFECT TRANSISTOR; FEMALE; FIELD EFFECT TRANSISTOR; HUMAN; MALE; MEASUREMENT ACCURACY; NON INVASIVE MEASUREMENT; PARKINSON DISEASE; PH; RELIABILITY; SALIVA ANALYSIS; SCREENING TEST; SENSITIVITY ANALYSIS; ANIMAL; CARBOHYDRATE METABOLISM; CASE CONTROL STUDY; CELL LINE; GENE EXPRESSION; GENETIC PROCEDURES; GENETICS; METABOLISM; MIDDLE AGED; SALIVA; SENSITIVITY AND SPECIFICITY;

AGED; ALZHEIMER DISEASE; ANIMALS; BIOMARKERS; BIOSENSING TECHNIQUES; CARBOHYDRATE METABOLISM; CASE-CONTROL STUDIES; CELL LINE; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; RECEPTORS, CELL SURFACE; SALIVA; SENSITIVITY AND SPECIFICITY; TREHALOSE;

EID: 84923869675     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117810     Document Type: Article

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