Naringin Attenuates the Development of Carrageenan-Induced Acute Lung Inflammation Through Inhibition of NF-κb, STAT3 and Pro-Inflammatory Mediators and Enhancement of IκBα and Anti-Inflammatory Cytokines

Inflammation

Volumn 38, Issue 2, 2015, Pages 846-857

  Ahmad, Sheikh Fayaz ^a   Attia, Sabry M ^a,b   Bakheet, Saleh A ^a   Zoheir, Khairy M A ^a,c   Ansari, Mushtaq Ahmad ^a   Korashy, Hesham M ^a   Abdel Hamied, Hala E ^d   Ashour, Abdelkader E ^a   Abd Allah, Adel R A ^a,b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Al Azhar University   (Egypt)

^c NATIONAL RESEARCH CENTRE   (Egypt)

^d AL AZHAR UNIVERSITY   (Egypt)

Author keywords

Carrageenan; Inflammatory mediators; Naringin; NF B p65; STAT3

Indexed keywords

AURANTIIN; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; PROSTAGLANDIN E2; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ANTIINFLAMMATORY AGENT; AUTACOID; CARRAGEENAN; CHUK PROTEIN, MOUSE; CYTOKINE; FLAVANONE DERIVATIVE; I KAPPA B KINASE; STAT3 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARRAGEENAN-INDUCED PLEURISY; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; LUNG PARENCHYMA; MOUSE; NONHUMAN; PLEURA FLUID; PROTEIN EXPRESSION; SINGLE DRUG DOSE; TH1 CELL; TH2 CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DOSE RESPONSE; METABOLISM; PLEURISY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRAGEENAN; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAVANONES; I-KAPPA B KINASE; INFLAMMATION MEDIATORS; MICE; MICE, INBRED BALB C; NF-KAPPA B; PLEURISY; STAT3 TRANSCRIPTION FACTOR;

EID: 84923845679     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9994-y     Document Type: Article

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