Continuous ultrafiltration membrane reactor coupled with nanofiltration for the enzymatic synthesis and purification of galactosyl-oligosaccharides

Separation and Purification Technology

Volumn 144, Issue , 2015, Pages 70-79

  Ren, Hengfei ^a   Fei, Junjie ^a   Shi, Xinchi ^a   Zhao, Ting ^a   Cheng, Hao ^a   Zhao, Nan ^a   Chen, Yong ^a   Ying, Hanjie ^a  

^a NANJING TECH UNIVERSITY   (China)

Author keywords

Continuous diafiltration; Galactosyl oligosaccharides; Nanofiltration; Ultrafiltration membrane reactor; galactosidase

Indexed keywords

BIOREACTORS; NANOFILTRATION; NANOFILTRATION MEMBRANES; OLIGOSACCHARIDES; SUBSTRATES; SUGARS; ULTRAFILTRATION;

AVERAGE RESIDENCE TIME; CONTINUOUS PRODUCTION; CONTINUOUS ULTRAFILTRATION; DIAFILTRATION; ENZYMATIC PRODUCTION; GALACTOSIDASES; GALACTOSYL-OLIGOSACCHARIDES; ULTRA-FILTRATION MEMBRANES;

COUPLED CIRCUITS;

EID: 84923790597     PISSN: 13835866     EISSN: 18733794     Source Type: Journal    
DOI: 10.1016/j.seppur.2015.02.020     Document Type: Article

References (41)

1. E. Betoret, N. Betoret, D. Vidal, and P. Fito Functional foods development: trends and technologies Trends Food Sci. Technol. 22 9 2011 498 508
2. S. Salminen, C. Bouley, M.C. Boutron, J.H. Cummings, A. Franck, G.R. Gibson, E. Isolauri, M.C. Moreau, M. Roberfroid, and I. Rowland Functional food science and gastrointestinal physiology and function Brit. J. Nutr. 80 S1 1998 S147 S171
3. L.J. Fooks, R. Fuller, and G.R. Gibson Prebiotics, probiotics and human gut microbiology Int. Dairy J. 9 1 1999 53 61
4. R.G. Gibson, and M.B. Roberfroid Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics J. Nutr. 125 1995 1401 1412
5. D. Granato, G.F. Branco, F. Nazzaro, A.G. Cruz, and J.A. Faria Functional foods and nondairy probiotic food development: trends, concepts, and products Compr. Rev. Food Sci. F. 9 3 2010 292 302
6. G.R. Gibson, P.B. Ottaway, and R.A. Rastall Prebiotics: New Developments in Functional Foods 2000 Chandos Oxford, UK
7. M.B. Roberfroid Prebiotics and probiotics: are they functional foods? Am. J. Clin. Nutr. 71 6 2000 1682s 1687s
8. H.C. Schoterman Galacto-oligosaccharides: properties and health aspects Adv. Dietary Fibre Technol. 42 2001 494 502
9. H. Tomomatsu Health effects of oligosaccharides Food Technol. 48 10 1994 61 65
10. T. Sako, K. Matsumoto, and R. Tanaka Recent progress on research and applications of nondigestible galacto-oligosaccharides Int. Dairy J. 9 1 1999 69 80
11. M.A. Boon, A.E.M. Janssen, and K. van't Riet Effect of temperature and enzyme origin on the enzymatic synthesis of oligosaccharides Enzyme Microbial Technol. 26 2 2000 271 281
12. T. Murata, and T. Usui Enzymatic synthesis of oligosaccharides and neoglycoconjugates Biosci. Biotechnol. Biochem. 70 5 2006 1049 1059
13. B.A. Rabiu, A.J. Jay, G.R. Gibson, and R.A. Rastall Synthesis and fermentation properties of novel galacto-oligosaccharides by β-galactosidases from Bifidobacterium species Appl. Environ. Microbiol. 67 6 2000 2526 2530
14. S.I. Mussatto, and I.M. Mancilha Non-digestible oligosaccharides: a review Carbohyd. Polym. 68 3 2007 587 597
15. S. Chockchaisawasdee, V.I. Athanasopoulos, K. Niranjan, and R.A. Rastall Synthesis of galacto-oligosaccharide from lactose using β-galactosidase from Kluyveromyces lactis: studies on batch and continuous UF membrane-fitted bioreactors Biotechnol. Bioeng. 89 4 2005 434 443
16. D.P. Torres, M.D.P.F. Gonçalves, J.A. Teixeira, and L.R. Rodrigues Galacto-oligosaccharides: production, properties, applications, and significance as prebiotics Compr. Rev. Food Sci. F. 9 5 2010 438 454
17. J.E. Prenosil, E. Stuker, and J.R. Bourne Formation of oligosaccharides during enzymatic lactose hydrolysis and their importance in a whey hydrolysis process: Part II: experimental Biotechnol. Bioeng. 30 9 1987 1026 1031
18. C.J. Zhou, and X.D. Chen Effects of temperature and pH on the catalytic activity of the immobilized β-galactosidase from Kluyveromyces lactis Biochem. Eng. J. 9 1 2001 33 40
19. Q.Z. Zhou, X.D. Chen, and X. Li Kinetics of lactose hydrolysis by β-galactosidase from Kluyveromyces lactis immobilized on cotton fabric Biotechnol. Bioeng. 81 2 2003 127 133
20. D.F. Neri, V.M. Balcão, M.G. Carneiro-da-Cunha, L.B. Carvalho Jr., and J.A. Teixeira Immobilization of β-galactosidase from Kluyveromyces lactis onto a polysiloxane-polyvinyl alcohol magnetic (mPOS-PVA) composite for lactose hydrolysis Catal. Commun. 9 14 2008 2334 2339
21. M.I. Foda, and M. LoÍpez-Leiva Continuous production of oligosaccharides from whey using a membrane reactor Process Biochem. 35 6 2000 581 587
22. L. Engel, M. Ebrahimi, and P. Czermak Membrane chromatography reactor system for the continuous synthesis of galactosyl-oligosaccharides Desalination 224 1 2008 46 51
23. R.D. Appel, A. Bairoch, and D.F. Hochstrasser A new generation of information retrieval tools for biologists: the example of the ExPASy WWW server Trends Biochem. Sci. 19 6 1994 258 260
24. M. Cheryan Ultrafiltration and Microfiltration Handbook 1998 CRC Press Boca Raton, Florida
25. P.Y. Pontalier, A. Ismail, and M. Ghoul Specific model for nanofiltration J. Food Eng. 40 3 1999 145 151
26. A.S. Grandison Separation processes in the food and biotechnology industries 1996 CRC Press
27. J. Kilduff, and W.J. Weber Jr Transport and separation of organic macromolecules in ultrafiltration processes Environ. Sci. Technol. 26 3 1992 569 577
28. W.Y. Li, J.D. Li, T.Q. Chen, and C.X. Chen Study on nanofiltration for purifying fructo-oligosaccharides, I. Operation modes J. Membr. Sci. 245 1 2004 123 129
29. N.J. Kruger The Bradford method for protein quantitation Basic Protein and Peptide Protocols vol. 32 1994 Humana Press Totowa, NJ 9 15
30. A. Gosling, G.W. Stevens, A.R. Barber, S.E. Kentish, and S.L. Gras Effect of the substrate concentration and water activity on the yield and rate of the transfer reaction of β-galactosidase from Bacillus circulans J. Agr. Food Chem. 59 7 2011 3366 3372
31. V.A. Botelho-Cunha, M. Mateus, J.C. Petrus, and M.N. vde Pinho Tailoring the enzymatic synthesis and nanofiltration fractionation of galacto-oligosaccharides Biochem. Eng. J. 50 1 2010 29 36
32. S.S. Kulkarni, E.W. Funk, and N.N. Li Ultrafiltration: membranes Membrane Handbook 1992 Van Nostrand Reinhold New York 408 431
33. A.K. Goulas, P.G. Kapasakalidis, H.R. Sinclair, R.A. Rastall, and A.S. Grandison Purification of oligosaccharides by nanofiltration J. Membr Sci. 209 1 2002 321 335
34. Y.M. Feng, X.L. Chang, W.H. Wang, and R.Y. Ma Separation of galacto-oligosaccharides mixture by nanofiltration J. Taiwan Inst. Chem. Eng. 40 3 2009 326 332
35. N. Aydogan, T. Gurkan, and L. Yilmaz Effect of operating parameters on the separation of sugars by nanofiltration Sep. Sci. Technol. 33 1998 1767 1785
36. L. Xu, S.Y. Wang, and X.Y. Zeng The maltitol purification and concentration by nanofiltration Desalination 184 1 2005 295 303
37. W.R. Bowen, and J.S. Welfoot Modelling of membrane nanofiltration - pore size distribution effects Chem. Eng. Sci. 57 8 2002 1393 1407
38. A.S. Grandison, and M.J. Lewis Separation Processes in the Food and Biotechnology Industries 1996 Woodhead Publishing Ltd Cambridge
39. A. Goulas, G. Tzortzis, and G.R. Gibson Development of a process for the production and purification of α- and β-galactooligosaccharides from Bifidobacterium bifidum NCIMB 41171 Int. Dairy J. 17 6 2007 648 656
40. A.K. Goulas, A.S. Grandison, and R.A. Rastall Fractionation of oligosaccharides by nanofiltration J. Sci. Food. Agric. 83 7 2003 675 680
41. J.E. Prenosil, E. Stuker, and J.R. Bourne Formation of oligosaccharides during enzymatic lactose. Part I. State of art Biotechnol. Bioeng. 30 9 1987 1019 1025