Surgical models of Roux-en-Y gastric bypass surgery and sleeve gastrectomy in rats and mice

Nature Protocols

Volumn 10, Issue 3, 2015, Pages 495-507

  Bruinsma, Bote G ^a   Uygun, Korkut ^a   Yarmush, Martin L ^a   Saeidi, Nima ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ARTICLE; BODY WEIGHT; FOOD INTAKE; FOOD PREFERENCE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; INTESTINE FLORA; MOUSE MODEL; NONHUMAN; OPERATION DURATION; PRIORITY JOURNAL; RAT MODEL; ROUX Y ANASTOMOSIS; SLEEVE GASTRECTOMY; STOMACH BYPASS; SURGICAL TECHNIQUE; ANIMAL; ANIMAL MODEL; GASTRECTOMY; GASTRIC BYPASS SURGERY; MOUSE; PROCEDURES; RAT;

ANIMALIA; MUS; RATTUS;

ANIMALS; GASTRECTOMY; GASTRIC BYPASS; MICE; MODELS, ANIMAL; RATS;

EID: 84923779876     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2015.027     Document Type: Article

References (37)

1. Ng, M. et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384, 766-781 (2014
2. Flegal, K.M., Carroll, M.D., Ogden, C.L. & Curtin, L.R. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 303, 235-241 (2010
3. Lenz, M., Richter, T. & Muhlhauser, I. The morbidity and mortality associated with overweight and obesity in adulthood: a systematic review. Dtsch. Arztebl. Int. 106, 641-648 (2009
4. Centers for Disease Control and Prevention. National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States, 2014 (US Department of Health and Human Services, 2014
5. Ogden, C.L., Carroll, M.D., Kit, B.K. & Flegal, K.M. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 311, 806-814 (2014
6. Buchwald, H. et al. Bariatric surgery: a systematic review and meta-Analysis. JAMA 292, 1724-1737 (2004
7. Sjostrom, L. et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N. Engl. J. Med. 351, 2683-2693 (2004
8. Stefater, M.A., Wilson-Perez, H.E., Chambers, A.P., Sandoval, D.A. & Seeley, R.J. All bariatric surgeries are not created equal: insights from mechanistic comparisons. Endocr. Rev. 33, 595-622 (2012
9. Mingrone, G. et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N. Engl. J. Med. 366, 1577-1585 (2012
10. Pories, W.J. et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann. Surg. 222, 339-350; discussion 350-352 (1995
11. Schauer, P.R. et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N. Engl. J. Med. 366, 1567-1576 (2012
12. Laferrere, B. Do we really know why diabetes remits after gastric bypass surgery? Endocrine 40, 162-167 (2011
13. Deitel, M. A brief history of the surgery for obesity to the present, with an overview of nutritional implications. J. Am. Coll. Nutr. 32, 136-142 (2013
14. Barnett, S.J. Surgical management of adolescent obesity. Adv. Pediatr. 60, 311-325 (2013
15. Bueter, M., Abegg, K., Seyfried, F., Lutz, T.A. & le Roux, C.W. Roux-en-Y gastric bypass operation in rats. J. Vis. Exp. 64, e3940 (2012
16. Buchwald, H., Estok, R., Fahrbach, K., Banel, D. & Sledge, I. Trends in mortality in bariatric surgery: a systematic review and meta-Analysis. Surgery 142, 621-632; discussion 632-635, (2007
17. John, S. & Hoegerl, C. Nutritional deficiencies after gastric bypass surgery. J. Am. Osteopath. Assoc. 109, 601-604 (2009
18. Chang, S.H. et al. The effectiveness and risks of bariatric surgery: an updated systematic review and meta-Analysis, 2003-2012. JAMA Surg. 149, 275-287 (2014
19. Schauer, P.R. et al. Bariatric surgery versus intensive medical therapy for diabetes-3-year outcomes. N. Engl. J. Med. 370, 2002-2013 (2014
20. Carlin, A.M. et al. The comparative effectiveness of sleeve gastrectomy, gastric bypass, and adjustable gastric banding procedures for the treatment of morbid obesity. Ann. Surg. 257, 791-797 (2013
21. Stylopoulos, N., Hoppin, A.G. & Kaplan, L.M. Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats. Obesity 17, 1839-1847 (2009
22. Zheng, H. et al. Meal patterns, satiety, and food choice in a rat model of Roux-en-Y gastric bypass surgery. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297, R1273-1282 (2009
23. Bueter, M. et al. Gastric bypass increases energy expenditure in rats. Gastroenterology 138, 1845-1853 (2010
24. Meguid, M.M. et al. A surgical rat model of human Roux-en-Y gastric bypass. J. Gastrointest. Surg. 8, 621-630 (2004
25. Patrikakos, P. et al. A surgical rat model of sleeve gastrectomy with staple technique: long-term weight loss results. Obes. Surg. 19, 1586-1590 (2009
26. Saeidi, N. et al. Sleeve gastrectomy and Roux-en-Y gastric bypass exhibit differential effects on food preferences, nutrient absorption and energy expenditure in obese rats. Int. J. Obes. 36, 1396-1402 (2012
27. Schlager, A. et al. A mouse model for sleeve gastrectomy: applications for diabetes research. Microsurgery 31, 66-71 (2011
28. Ye, J. et al. GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents. Am. J. Physiol. Regul. Integr. Comp. Physiol. 306, R352-R362 (2014
29. Hao, Z., Zhao, Z., Berthoud, H.R. & Ye, J. Development and verification of a mouse model for Roux-en-Y gastric bypass surgery with a small gastric pouch. PloS ONE 8, e52922 (2013
30. Wilson-Perez, H.E. et al. The effect of vertical sleeve gastrectomy on food choice in rats. Int. J. Obes. 37, 288-295 (2013
31. Chambers, A.P. et al. Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. Physiol. Behav. 105, 120-123 (2011
32. Saeidi, N. et al. Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass. Science 341, 406-410 (2013
33. Kucharczyk, J., Nestoridi, E., Kvas, S., Andrews, R. & Stylopoulos, N. Probing the mechanisms of the metabolic effects of weight loss surgery in humans using a novel mouse model system. J. Surg. Res. 179, e91-e98 (2013
34. Hariri, N. & Thibault, L. High-fat diet-induced obesity in animal models. Nutr. Res. Rev. 23, 270-299 (2010
35. Chambers, A.P. et al. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology 141, 950-958 (2011
36. Wickremesekera, K., Miller, G., Naotunne, T.D., Knowles, G. & Stubbs, R.S. Loss of insulin resistance after Roux-en-Y gastric bypass surgery: a time course study. Obes. Surg. 15, 474-481 (2005
37. Rizzello, M. et al. Early postoperative insulin-resistance changes after sleeve gastrectomy. Obes. Surg. 20, 50-55 (2010