Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells

International Journal of Molecular Medicine

Volumn 35, Issue 4, 2015, Pages 1011-1016

  Song, Young Chan ^a   Lee, Yonghee ^a   Kim, Hyeong Mi ^a   Hyun, Moo Yeol ^a   Lim, Yun Young ^a   Song, Kye Yong ^a   Kim, Beom Joon ^a  

^a Chung Ang University College of Medicine   (South Korea)

Author keywords

B16F10 melanoma cells; Extracellular signal regulated kinases; Glycogen synthase kinase 3 ; Melanin synthesis; Microphthalmia associated transcription factor; Phosphotidyl inositol 3 kinase AKT; Tyrosinase

Indexed keywords

ALPHA INTERMEDIN; BERBERINE; GLYCOGEN SYNTHASE KINASE 3BETA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MONOPHENOL MONOOXYGENASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MELANIN;

ARTICLE; CELL FREE SYSTEM; CELL LYSATE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MELANOGENESIS; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SKIN PIGMENTATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; DRUG EFFECTS; EXPERIMENTAL MELANOMA; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; BERBERINE; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCOGEN SYNTHASE KINASE 3; MELANINS; MELANOMA, EXPERIMENTAL; MONOPHENOL MONOOXYGENASE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84923699864     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2113     Document Type: Article

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